GenePage for the arnF gene of Escherichia coli K-12

Primary Gene Name: arnF
EcoGene Accession Number: EG14094
K-12 Gene Accession Number: ECK2252
MG1655 Gene Identifier: b2258
Gene Name Mnemonic: ara4N (4-amino-4-deoxy-L-arabinose)
Alternate Gene Symbols: pbgE3(S.t.); pmrM(S.t.); yfbJ
Description: Undecaprenyl phosphate-alpha-L-ara4N exporter; flippase ArnEF subunit
  # bp Upstream # bp Downstream
MW: 14085.19 ---------128 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2372892
Left Intergenic Region

Name: arnE_arnF

Length: 1 bp overlap

Orientation: Codirectional+

Left_end: 2372892

Right_end: 2372892

Centisome: 51.12

Genomic Address
Clockwise
Minute or Centisome (%) = 51.12
Right End: 2373278
Right Intergenic Region

Name: arnF_pmrD

Length: 7 bp overlap

Orientation: Convergent

Left_end: 2373272

Right_end: 2373278

Centisome: 51.13

Export via ArnEF is required for the modification of lipid A phosphates with aminoarabinose that is needed for polymyxin B and cationic antimicrobial peptide resistance (Yan, 2007). ArnEF is also known as the probable 4-amino-4-deoxy-L-arabinose(Ara4N)-phosphoundecaprenol flippase. ArnF(YfbJ) has been reported to be required for swarming phenotype (Inoue, 2007). The arnBCADTEF operon promoter region binds FNR and arnBCADTEF expression is repressed by FNR (Federowicz, 2014).

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BamHI EcoRI HindIII