GenePage for the abgA gene of Escherichia coli K-12

Primary Gene Name: abgA
EcoGene Accession Number: EG13352
K-12 Gene Accession Number: ECK1334
MG1655 Gene Identifier: b1338
Gene Name Mnemonic: Aminobenzoyl-glutamate
Alternate Gene Symbols: ydaJ
Description: p-Aminobenzoyl-glutamate hydrolase, A subunit; PGH; manganese-dependent; required for p-aminobenzoyl-glutamate utilization
  # bp Upstream # bp Downstream
Verified Start MW: 46588.22 ---------436 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 1403255
Left Intergenic Region

Name: abgB_abgA

Length: 1 bp overlap

Orientation: Codirectional-

Left_end: 1403255

Right_end: 1403255

Centisome: 30.23

Genomic Address
Counterclockwise
Minute or Centisome (%) = 30.23
Right End: 1404565
Right Intergenic Region

Name: abgA_abgR

Length: 175 bp gap

Orientation: Divergent

Left_end: 1404566

Right_end: 1404740

Centisome: 30.26

abgAB expression is required for catabolism to feed p-aminobenzoate auxotrophs (Hussein, 1998; Carter, 2007). AbgAB (PGH) catalyzes the hydrolysis of folate metabolite p-aminobenzoyl-glutamate to p-aminobenzoate (Carter, 2007; Green, 2010). The abg operon is silent and an AbgR inducer has not been found (Hussein, 1998; Carter, 2007). AbgA is a member of the M20 peptidase family. abgA and abgB are paralogs. AbgABT does not degrade dipeptides; the physiological role of abgABT should be clarified when the inducer for AbgR is elucidated (Green, 2010).

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BamHI EcoRI HindIII