GenePage for the fadM gene of Escherichia coli K-12

Primary Gene Name: fadM
EcoGene Accession Number: EG13251
K-12 Gene Accession Number: ECK0437
MG1655 Gene Identifier: b0443
Gene Name Mnemonic: Thioesterase
Alternate Gene Symbols: tesC; ybaW
Description: Long-chain acyl-CoA thioesterase III
  # bp Upstream # bp Downstream
MW: 15088.31 ---------132 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 464402
Left Intergenic Region

Name: ybaV_fadM

Length: 93 bp gap

Orientation: Codirectional+

Left_end: 464309

Right_end: 464401

Centisome: 10.00

Genomic Address
Clockwise
Minute or Centisome (%) = 10.01
Right End: 464800
Right Intergenic Region

Name: fadM_queC

Length: 51 bp gap

Orientation: Convergent

Left_end: 464801

Right_end: 464851

Centisome: 10.01

3,5-tetradecadienoyl-CoA is the preferred substrate for thioesterase III, which is induced by fatty acids, suggesting a role in beta-oxidation of fatty acids (Nie, 2008). fadM(ybaW) is part of the FadR regulon (Feng, 2009). FadM is a member of the HotDog superfamily of thioesterases and dehydratases (Pfam CL0050, PF03061; PDB 1NJK) (Dillon, 2004).

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII