GenePage for the dinB gene of Escherichia coli K-12

Primary Gene Name: dinB
EcoGene Accession Number: EG13141
K-12 Gene Accession Number: ECK0232
MG1655 Gene Identifier: b0231
Gene Name Mnemonic: Damage inducible
Alternate Gene Symbols: dinP
Description: DNA polymerase IV, capable of translesion synthesis; overexpression enhances mutagenesis; mediates targeted mutagenesis by 4-NQO; intrinsic AP lyase activity
  # bp Upstream # bp Downstream
MW: 39515.92 ---------351 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 250898
Left Intergenic Region

Name: lafU_dinB

Length: 70 bp gap

Orientation: Codirectional+

Left_end: 250828

Right_end: 250897

Centisome: 5.40

Genomic Address
Clockwise
Minute or Centisome (%) = 5.41
Right End: 251953
Right Intergenic Region

Name: dinB_yafN

Length: 51 bp gap

Orientation: Codirectional+

Left_end: 251954

Right_end: 252004

Centisome: 5.43

DinB and YafP reduce 4-nitroquinoline-1-oxide-induced mutagenicity (Gutierrez, 2011). Part of dinB-yafNOP operon. LexA regulon. The phenotype of some dinB alleles to reduce spontaneous mutations may be due to polarity effects.

Go to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePageGo to GenePage

BamHI EcoRI HindIII