GenePage for the hslO gene of Escherichia coli K-12

Primary Gene Name: hslO
EcoGene Accession Number: EG12930
K-12 Gene Accession Number: ECK3388
MG1655 Gene Identifier: b3401
Gene Name Mnemonic: Heat shock locus
Alternate Gene Symbols: yrfI
Description: Hsp33, oxidative stress-induced heat shock chaperone; C-terminal zinc-binding motif regulates Hsp33 activity
  # bp Upstream # bp Downstream
MW: 32534.48 ---------292 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3529774
Left Intergenic Region

Name: hslR_hslO

Length: 24 bp gap

Orientation: Codirectional+

Left_end: 3529750

Right_end: 3529773

Centisome: 76.05

Genomic Address
Clockwise
Minute or Centisome (%) = 76.05
Right End: 3530652
Right Intergenic Region

Name: hslO_yhgE

Length: 62 bp gap

Orientation: Convergent

Left_end: 3530653

Right_end: 3530714

Centisome: 76.06

masks the hydrophobic surfaces under reduced conditions, release of zinc during oxidative induced disulfide bond formation results in the unmasking of the hydrophobic surfaces and partial activation of chaperone function. The redox induced secondary structure changes are primarily localized in the C-terminus, leaving the N-terminus which harbors the dimerization interface largely unaltered.

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BamHI EcoRI HindIII