GenePage for the bdcA gene of Escherichia coli K-12

Primary Gene Name: bdcA
EcoGene Accession Number: EG12528
K-12 Gene Accession Number: ECK4243
MG1655 Gene Identifier: b4249
Gene Name Mnemonic: Biofilm Dispersal via C-di-GMP
Alternate Gene Symbols: yjgI
Description: c-di-GMP-binding biofilm dispersal mediator protein
  # bp Upstream # bp Downstream
MW: 24598.14 ---------237 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 4473340
Left Intergenic Region

Name: yjgH_bdcA

Length: 130 bp gap

Orientation: Codirectional-

Left_end: 4473210

Right_end: 4473339

Centisome: 96.37

Genomic Address
Counterclockwise
Minute or Centisome (%) = 96.37
Right End: 4474053
Right Intergenic Region

Name: bdcA_bdcR

Length: 70 bp gap

Orientation: Divergent

Left_end: 4474054

Right_end: 4474123

Centisome: 96.39

BdcA binds c-di-GMP, reducing free c-di-GMP and causing biofilm dispersal; BdcA does not degrade c-di-GMP; a E50Q mutation increases c-di-GMP binding and increases biofilm dispersal (Ma, 2011). The divergent BdcR is a transcriptional repressor for the bdcA gene (Ma, 2011). COG1028 family

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BamHI EcoRI HindIII