GenePage for the hofB gene of Escherichia coli K-12

Primary Gene Name: hofB
EcoGene Accession Number: EG12106
K-12 Gene Accession Number: ECK0106
MG1655 Gene Identifier: b0107
Gene Name Mnemonic: Homologous to fim
Alternate Gene Symbols: hopB
Description: T2SE family predicted protein secretion protein; predicted P-loop ATPase, function unknown
  # bp Upstream # bp Downstream
MW: 50615.33 ---------461 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 115714
Left Intergenic Region

Name: hofC_hofB

Length: 11 bp overlap

Orientation: Codirectional-

Left_end: 115714

Right_end: 115724

Centisome: 2.49

Genomic Address
Counterclockwise
Minute or Centisome (%) = 2.49
Right End: 117099
Right Intergenic Region

Name: hofB_ppdD

Length: 9 bp gap

Orientation: Codirectional-

Left_end: 117100

Right_end: 117108

Centisome: 2.52

HofB(HopB) has GspE-like N-terminal T2SE-Nter (PF05157) and central T2SE (PF00437) domains; HofB also has a conserved Pfam-B 498 C-terminal domain (PB000498). An unrelated hopB gene (for host function of plasmid maintenance) mappng near but not in gyrB is defective in stable maintenance of the mini-F plasmid, has not yet been mapped to a coding region, and has sometimes been confused with this hopB gene (Niki, 1988; Ogura, 1990). gspE, hofB and yggR are paralogs.

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BamHI EcoRI HindIII