GenePage for the kup gene of Escherichia coli K-12

Primary Gene Name: kup
EcoGene Accession Number: EG11541
K-12 Gene Accession Number: ECK3741
MG1655 Gene Identifier: b3747
Gene Name Mnemonic: K+ UPtake
Alternate Gene Symbols: trkD
Description: Major constitutive K+ uptake permease at acidic pH; also transports Cs+ and Rb+
  # bp Upstream # bp Downstream
MW: 69294.13 ---------622 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3931316
Left Intergenic Region

Name: ravA_kup

Length: 222 bp gap

Orientation: Divergent

Left_end: 3931094

Right_end: 3931315

Centisome: 84.69

Genomic Address
Clockwise
Minute or Centisome (%) = 84.70
Right End: 3933184
Right Intergenic Region

Name: kup_rbsD

Length: 166 bp gap

Orientation: Codirectional+

Left_end: 3933185

Right_end: 3933350

Centisome: 84.74

Unlike the other potassium transporters, Kup transports Cs+ and Rb+ as well as K+; this finding corrects an earlier report of Rb+ ion discrimination by Kup, from the same lab (Rhoads, 1977; Bossemeyer, 1989). The kup-ravA,viaA divergent operon promoter region binds FNR (Federowicz, 2014).

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BamHI EcoRI HindIII