GenePage for the ebgC gene of Escherichia coli K-12

Primary Gene Name: ebgC
EcoGene Accession Number: EG10253
K-12 Gene Accession Number: ECK3067
MG1655 Gene Identifier: b3077
Gene Name Mnemonic: Evolved beta-galactosidase
Alternate Gene Symbols: None
Description: Evolved beta-D-galactosidase, beta subunit; cupin superfamily; normal substrate and function unknown; alpha(4)beta(4) holoenzyme
  # bp Upstream # bp Downstream
MW: 17456.62 ---------149 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 3225722
Left Intergenic Region

Name: ebgA_ebgC

Length: 4 bp overlap

Orientation: Codirectional+

Left_end: 3225722

Right_end: 3225725

Centisome: 69.50

Genomic Address
Clockwise
Minute or Centisome (%) = 69.50
Right End: 3226171
Right Intergenic Region

Name: ebgC_ygjI

Length: 62 bp gap

Orientation: Codirectional+

Left_end: 3226172

Right_end: 3226233

Centisome: 69.50

EbgC is required for full activity: it has been suggested to be involved in the rate-limiting degalactosylation step and/or in electrophilic catalysis by the EbgA active site Mg(2+). EbgC is a distant homolog of YiaL, YhcH and TabA(YjgK), all four match PF04074; although homologous to the beta subunit of the EbgAC evolved beta-galactosidase, no potential EbgA-like alpha subunit partners are apparent for the other three DUF386 family paralogs.

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BamHI EcoRI HindIII