GenePage for the dedA gene of Escherichia coli K-12

Primary Gene Name: dedA
EcoGene Accession Number: EG10216
K-12 Gene Accession Number: ECK2311
MG1655 Gene Identifier: b2317
Gene Name Mnemonic: Downstream E. coli DNA
Alternate Gene Symbols: None
Description: DedA family inner membrane protein, function unknown
  # bp Upstream # bp Downstream
MW: 24510.25 ---------219 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 2434082
Left Intergenic Region

Name: accD_dedA

Length: 155 bp gap

Orientation: Codirectional-

Left_end: 2433927

Right_end: 2434081

Centisome: 52.44

Genomic Address
Counterclockwise
Minute or Centisome (%) = 52.44
Right End: 2434741
Right Intergenic Region

Name: dedA_truA

Length: 82 bp gap

Orientation: Codirectional-

Left_end: 2434742

Right_end: 2434823

Centisome: 52.45

DedA superfamily proteins YqjA and YghB likely have redundant functions since only a double mutant has defects; DedA superfamily members yabI or yohD can complement the yqjA yghB double mutant when overproduced, but a dedA clone cannot complement (Thompkins, 2008). The E. coli K-12 DedA superfamily (SNARE associated Golgi protein/PF09335) has eight paralogs in two families, the COG0586 DedA/YghB family (including the DedA/YabI/YohD subfamily and the general envelope maintenance protein YghB/YqjA subfamily) and the YdjX family (including the COG0398 YdjX/YdjZ subfamily and the COG1238 YqaA subfamily) (Doerrler, 2013; K.E.R.).

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BamHI EcoRI HindIII