GenePage for the clpP gene of Escherichia coli K-12

Primary Gene Name: clpP
EcoGene Accession Number: EG10158
K-12 Gene Accession Number: ECK0431
MG1655 Gene Identifier: b0437
Gene Name Mnemonic: Caseinolytic protease
Alternate Gene Symbols: lopP; wseA
Description: Proteolytic subunit of ClpXP and ClpAP ATP-dependent proteases; protease Ti
  # bp Upstream # bp Downstream
Verified Start MW: 23186.65 ---------207 aa Pre-Run BlastP UniProt
Pre-Run BlastP NR+Env
Left End: 456677
Left Intergenic Region

Name: tig_clpP

Length: 245 bp gap

Orientation: Codirectional+

Left_end: 456432

Right_end: 456676

Centisome: 9.83

Genomic Address
Clockwise
Minute or Centisome (%) = 9.84
Right End: 457300
Right Intergenic Region

Name: clpP_clpX

Length: 125 bp gap

Orientation: Codirectional+

Left_end: 457301

Right_end: 457425

Centisome: 9.85

ClpP can simultaneously bind ClpX and ClpA to form a heteromeric complex. Binds TrxA (Kumar, 2004). ClpP is required for MazF-mediated cell death after either DNA damage or inhibition of translation (Amitai, 2009). The first 14 aa of ClpP are proteolytically processed in trans by another ClpP molecule (Maurizi, 1990).

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BamHI EcoRI HindIII