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EcogeneTopic Page
TopicPage for The Ribosome of Escherichia coli K-12
 | Protein Translation          |
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Description:
The Ribosome is comprised of rRNAs and rProteins.
Details:
The crystal structure of the ribosome is known. Recent include the following PDB structures: 2QAL, 2QAM, 2QAN, 2QAO, 2QB9, 2QBA, 2QBB, 2QBC, 2QBD, 2QBE, 2QBF, 2QBG, 2QBH, 2QBI, 2QBJ, 2QBK, 2Z4K, 2Z4L, 2Z4M, 2Z4N (Borovinskaya, 2007). A comprehensive survey and additional PDBs will be added to this page at a later date.
Bibliography (30 total) : Review Only   Up
- 2009
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Gürel G, Blaha G, Moore PB, Steitz TA (2009) U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. J Mol Biol 389:146-56
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Zundel MA, Basturea GN, Deutscher MP (2009) Initiation of ribosome degradation during starvation in Escherichia coli. RNA 15:977-83
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Scheres SH, Valle M, Grob P, Nogales E, Carazo JM (2009) Maximum likelihood refinement of electron microscopy data with normalization errors. J Struct Biol 166:234-40
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Ramaswamy P, Woodson SA (2009) S16 throws a conformational switch during assembly of 30S 5' domain. Nat Struct Mol Biol 16:438-45
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Ederth J, Mandava CS, Dasgupta S, Sanyal S (2009) A single-step method for purification of active His-tagged ribosomes from a genetically engineered Escherichia coli. Nucleic Acids Res 37:e15
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Petropoulos AD, Kouvela EC, Starosta AL, Wilson DN, Dinos GP, Kalpaxis DL (2009) Time-resolved binding of azithromycin to Escherichia coli ribosomes. J Mol Biol 385:1179-92
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Brandt F, Etchells SA, Ortiz JO, Elcock AH, Hartl FU, Baumeister W (2009) The native 3D organization of bacterial polysomes. Cell 136:261-71
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Kipper K, Hetényi C, Sild S, Remme J, Liiv A (2009) Ribosomal intersubunit bridge B2a is involved in factor-dependent translation initiation and translational processivity. J Mol Biol 385:405-22
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Dreyfus M (2009) Killer and protective ribosomes. Prog Mol Biol Transl Sci 85:423-66 Review
- 2008
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Romanowska J, Setny P, Trylska J (2008) Molecular dynamics study of the ribosomal A-site. J Phys Chem B 112:15227-43
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Noll H (2008) The discovery of polyribosomes. Bioessays 30:1220-34
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Adilakshmi T, Bellur DL, Woodson SA (2008) Concurrent nucleation of 16S folding and induced fit in 30S ribosome assembly. Nature 455:1268-72
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Lancaster L, Lambert NJ, Maklan EJ, Horan LH, Noller HF (2008) The sarcin-ricin loop of 23S rRNA is essential for assembly of the functional core of the 50S ribosomal subunit. RNA 14:1999-2012
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LeBarron J, Grassucci RA, Shaikh TR, Baxter WT, Sengupta J, Frank J (2008) Exploration of parameters in cryo-EM leading to an improved density map of the E. coli ribosome. J Struct Biol 164:24-32
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Trabuco LG, Villa E, Mitra K, Frank J, Schulten K (2008) Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics. Structure 16:673-83
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Kelly DF, Dukovski D, Walz T (2008) Monolayer purification: a rapid method for isolating protein complexes for single-particle electron microscopy. Proc Natl Acad Sci U S A 105:4703-8
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Pai RD, Zhang W, Schuwirth BS, Hirokawa G, Kaji H, Kaji A, Cate JH (2008) Structural Insights into ribosome recycling factor interactions with the 70S ribosome. J Mol Biol 376:1334-47
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Bremer H, Dennis P (2008) Feedback control of ribosome function in Escherichia coli. Biochimie 90:493-9
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Petropoulos AD, Kouvela EC, Dinos GP, Kalpaxis DL (2008) Stepwise binding of tylosin and erythromycin to Escherichia coli ribosomes, characterized by kinetic and footprinting analysis. J Biol Chem 283:4756-65
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Basu A, Samanta D, Das D, Chowdhury S, Bhattacharya A, Ghosh J, Das A, Dasgupta C (2008) In vitro protein folding by E. coli ribosome: unfolded protein splitting 70S to interact with 50S subunit. Biochem Biophys Res Commun 366:598-603
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Basu A, Samanta D, Bhattacharya A, Das A, Das D, Dasgupta C (2008) Protein folding following synthesis in vitro and in vivo: association of newly synthesized protein with 50S subunit of E. coli ribosome. Biochem Biophys Res Commun 366:592-7
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Iost I, Charollais J, Vinh J, Pflieger D (2008) Characterization of E. coli ribosomal particles : combined analysis of whole proteins by mass spectrometry and of proteolytic digests by liquid chromatography-tandem mass spectrometry. Methods Mol Biol 432:321-41
- 2007
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Marzi S, Myasnikov AG, Serganov A, Ehresmann C, Romby P, Yusupov M, Klaholz BP (2007) Structured mRNAs regulate translation initiation by binding to the platform of the ribosome. Cell 130:1019-31
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Kaczanowska M, Rydén-Aulin M (2007) Ribosome biogenesis and the translation process in Escherichia coli. Microbiol Mol Biol Rev 71:477-94 Review
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Sanders CL, Curran JF (2007) Genetic analysis of the E site during RF2 programmed frameshifting. RNA 13:1483-91
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Borovinskaya MA, Pai RD, Zhang W, Schuwirth BS, Holton JM, Hirokawa G, Kaji H, Kaji A, Cate JH (2007) Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat Struct Mol Biol 14:727-32
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Kim HM, Yeom JH, Ha HJ, Kim JM, Lee K (2007) Functional analysis of the residues C770 and G771 of E. coli 16S rRNA implicated in forming the intersubunit bridge B2c of the ribosome. J Microbiol Biotechnol 17:1204-7
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Berk V, Cate JH (2007) Insights into protein biosynthesis from structures of bacterial ribosomes. Curr Opin Struct Biol 17:302-9 Review
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Wilson DN, Nierhaus KH (2007) The weird and wonderful world of bacterial ribosome regulation. Crit Rev Biochem Mol Biol 42:187-219 Review
- 2005
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