EcoGene

GenePage for the der gene of Escherichia coli K-12

Primary Gene Name: der
EcoGene Accession Number: EG14207
K-12 Gene Accession Number: ECK2507
MG1655 Gene Identifier: b2511

Common Core

CommonCore-5

Conserved P-loop GTPases/ATPases

Essential Genes

Y-synonyms

Gene Name Mnemonic: Double ERa-like domains

Alternate Gene Symbols: engA, yfgK

Description:
Multicopy suppressor of ftsJ; depleted cells form filaments with defective chromosome segregation; GTPase

Pre-Run BlastP UniProt

Protein Sequence: ------------ MW: 55035.87------490 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 2633906 ----------------- Counterclockwise ----------------- Right End: 2635378
Left Inter Gene Info Minute or Centisome (%) = 56.77 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

Der-depletion alters ribosome stability and/or biogenesis, as evidenced by polysome profiles (Bharat, 2006). Der has two tandem GTP-binding domains. der is an essential gene.