EcoGene

GenePage for the nrdR gene of Escherichia coli K-12

Primary Gene Name: nrdR
EcoGene Accession Number: EG11320
K-12 Gene Accession Number: ECK0407
MG1655 Gene Identifier: b0413

Abasic site:C binding

Common Core

CommonCore-5

Structure2Function Project

Y-synonyms

Gene Name Mnemonic: Nucleotide reductase

Alternate Gene Symbols: ribX, ybaD

Description:
Nrd regulon repressor

Pre-Run BlastP UniProt

Protein Sequence: ------------ MW: 17228.89------149 aa ------------ Pre-Run BlastP NR+Env

Genomic Address
Left End: 432226 ----------------- Clockwise ----------------- Right End: 432675
Left Inter Gene Info Minute or Centisome (%) = 9.32 Right Inter Gene Info

PDF EcoMap

Curator or user-submitted Comments:

NrdR has been shown to regulate all three Nrd systems and to bind to the predicted NrdR binding sites (Torrents, 2007). Homologous to S. coelicolor NrdR (Borovok, 2004). Predicted binding sites has been reported for the nrdAB, nrdDG, and nrdHIEF operons (Rodionova, 2005). This corresponds to putative TF Binding SIte Cluster E581 for nrdD and nrdA (Qin, 2003). Binds TrxA (Kumar, 2004). First gene in putative nrdR-ribDE-nusB operon. Also refered to as nrdR in an unpublished comparative analysis (Borovok, 2005, in GenBank AM076828).