Blast performed on February-12-2007
BLASTP 2.2.13 [Nov-27-2005]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Database: nr_env 
           5,549,519 sequences; 1,762,256,069 total letters

Query= EG11910 pflD 
         (765 letters)

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|NP_418386.1|  predicted formate acetyltransferase 2 (pyr...  1522   0.0   
ref|ZP_00707894.1|  COG1882: Pyruvate-formate lyase [Escheri...  1517   0.0   
ref|ZP_00736216.1|  COG1882: Pyruvate-formate lyase [Escheri...  1516   0.0   
ref|ZP_00701955.1|  COG1882: Pyruvate-formate lyase [Escheri...  1516   0.0   
ref|NP_709751.1|  formate acetyltransferase 2 [Shigella flex...  1514   0.0   
ref|ZP_00714537.1|  COG1882: Pyruvate-formate lyase [Escheri...  1513   0.0   
ref|ZP_00722395.1|  COG1882: Pyruvate-formate lyase [Escheri...  1513   0.0   
ref|ZP_00709599.1|  COG1882: Pyruvate-formate lyase [Escheri...  1511   0.0   
ref|YP_543485.1|  formate acetyltransferase 2 [Escherichia c...  1509   0.0   
ref|ZP_00921230.1|  COG1882: Pyruvate-formate lyase [Shigell...  1507   0.0   
ref|ZP_00724288.1|  COG1882: Pyruvate-formate lyase [Escheri...  1507   0.0   
ref|ZP_00696787.1|  COG1882: Pyruvate-formate lyase [Shigell...  1505   0.0   
ref|NP_756764.1|  Formate acetyltransferase 2 [Escherichia c...  1505   0.0   
ref|NP_290588.1|  formate acetyltransferase 2 [Escherichia c...  1504   0.0   
ref|YP_405222.1|  formate acetyltransferase 2 [Shigella dyse...  1498   0.0   
ref|NP_462994.1|  putative pyruvate formate lyase II [Salmon...  1409   0.0   
ref|YP_878969.1|  pyruvate formate-lyase [Clostridium novyi ...   627   e-178 
ref|ZP_00910118.1|  Pyruvate formate-lyase [Clostridium beij...   607   e-172 
pdb|1R8W|A  Chain A, Native Structure Of The B12-Independent...   604   e-171 
ref|YP_878877.1|  pyruvate formate-lyase [Clostridium novyi ...   602   e-170 
ref|YP_877303.1|  pyruvate formate-lyase [Clostridium novyi ...   596   e-168 
ref|NP_781591.1|  formate acetyltransferase 2 [Clostridium t...   593   e-167 
ref|YP_356813.1|  glycerol dehydratase [Pelobacter carbinoli...   590   e-166 
ref|ZP_00813776.1|  Pyruvate formate-lyase [Shewanella putre...   573   e-161 
gb|ABC25539.1|  glycerol dehydratase [Roseburia inulinivorans]    560   e-158 
ref|YP_425991.1|  Pyruvate formate-lyase [Rhodospirillum rub...   545   e-153 
ref|ZP_00907194.1|  Pyruvate formate-lyase [Clostridium beij...   543   e-152 
ref|YP_531045.1|  pyruvate formate-lyase [Rhodopseudomonas p...   521   e-146 
ref|ZP_01352562.1|  pyruvate formate-lyase [Clostridium phyt...   517   e-144 
ref|ZP_01372386.1|  pyruvate formate-lyase [Desulfitobacteri...   509   e-142 
ref|NP_070278.1|  pyruvate formate-lyase 2 (pflD) [Archaeogl...   496   e-138 
ref|NP_756397.1|  hypothetical protein c4537 [Escherichia co...   480   e-133 
ref|ZP_01362669.1|  Pyruvate formate-lyase [Clostridium sp. ...   477   e-132 
ref|ZP_00365816.1|  COG1882: Pyruvate-formate lyase [Strepto...   476   e-132 
ref|ZP_01476143.1|  hypothetical protein VEx2w_02001343 [Vib...   476   e-132 
ref|NP_801077.1|  putative pyruvate formate lyase [Vibrio pa...   476   e-132 
ref|YP_601373.1|  Formate acetyltransferase [Streptococcus p...   475   e-132 
ref|YP_281195.1|  formate acetyltransferase [Streptococcus p...   474   e-132 
ref|ZP_00722160.1|  COG1882: Pyruvate-formate lyase [Escheri...   474   e-132 
ref|NP_269993.1|  putative pyruvate formate-lyase 2 [Strepto...   474   e-131 
ref|ZP_00925323.1|  COG1882: Pyruvate-formate lyase [Escheri...   474   e-131 
ref|NP_608068.1|  putative pyruvate formate-lyase 2 [Strepto...   473   e-131 
ref|YP_407215.1|  putative formate acetyltransferase [Shigel...   473   e-131 
ref|NP_665553.1|  putative pyruvate formate-lyase [Streptoco...   473   e-131 
ref|ZP_00698439.1|  COG1882: Pyruvate-formate lyase [Shigell...   473   e-131 
ref|YP_599421.1|  Formate acetyltransferase [Streptococcus p...   472   e-131 
ref|NP_687365.1|  formate acetyltransferase [Streptococcus a...   472   e-131 
ref|ZP_00780073.1|  pyruvate formate-lyase [Streptococcus ag...   471   e-131 
ref|ZP_01588855.1|  pyruvate formate-lyase [Enterobacter sp....   471   e-131 
ref|YP_603331.1|  Formate acetyltransferase [Streptococcus p...   471   e-131 
ref|YP_539843.1|  putative formate acetyltransferase 3 [Esch...   471   e-131 
ref|YP_061061.1|  Formate acetyltransferase [Streptococcus p...   471   e-131 
ref|YP_309787.1|  putative formate acetyltransferase [Shigel...   471   e-131 
ref|NP_752838.1|  Putative formate acetyltransferase 3 [Esch...   471   e-130 
ref|NP_455377.1|  putative formate acetyltransferase 3 [Salm...   470   e-130 
ref|ZP_00908945.1|  Pyruvate formate-lyase [Clostridium beij...   470   e-130 
ref|ZP_00703131.1|  COG1882: Pyruvate-formate lyase [Escheri...   470   e-130 
ref|ZP_00720244.1|  COG1882: Pyruvate-formate lyase [Escheri...   470   e-130 
ref|ZP_00710729.1|  COG1882: Pyruvate-formate lyase [Escheri...   470   e-130 
gb|EAY48848.1|  pyruvate formate-lyase [Escherichia coli B]       469   e-130 
ref|NP_786017.1|  formate C-acetyltransferase [Lactobacillus...   469   e-130 
ref|ZP_00784845.1|  pyruvate formate-lyase [Streptococcus ag...   469   e-130 
ref|YP_283106.1|  formate acetyltransferase [Streptococcus p...   469   e-130 
ref|NP_286587.1|  Pyruvate-formate lyase [Escherichia coli O...   469   e-130 
ref|NP_706700.1|  putative formate acetyltransferase [Shigel...   469   e-130 
ref|YP_688342.1|  putative formate acetyltransferase [Shigel...   468   e-130 
ref|NP_459820.1|  putative pyruvate formate lyase [Salmonell...   468   e-130 
ref|ZP_00705044.1|  COG1882: Pyruvate-formate lyase [Escheri...   468   e-130 
ref|ZP_00789518.1|  pyruvate formate-lyase [Streptococcus ag...   468   e-130 
ref|ZP_00735320.1|  COG1882: Pyruvate-formate lyase [Escheri...   468   e-130 
ref|YP_001004997.1|  putative formate acetyltransferase [Yer...   467   e-129 
ref|YP_215825.1|  putative pyruvate formate lyase [Salmonell...   467   e-129 
ref|YP_402437.1|  putative formate acetyltransferase [Shigel...   467   e-129 
ref|NP_415344.1|  predicted pyruvate formate lyase [Escheric...   467   e-129 
ref|ZP_00924764.1|  COG1882: Pyruvate-formate lyase [Escheri...   467   e-129 
ref|YP_151135.1|  putative formate acetyltransferase 3 [Salm...   466   e-129 
ref|ZP_00825734.1|  COG1882: Pyruvate-formate lyase [Yersini...   464   e-129 
ref|ZP_01258449.1|  putative pyruvate formate lyase [Vibrio ...   462   e-128 
ref|ZP_00831656.1|  COG1882: Pyruvate-formate lyase [Yersini...   462   e-128 
ref|ZP_00823788.1|  COG1882: Pyruvate-formate lyase [Yersini...   461   e-128 
ref|ZP_01534560.1|  pyruvate formate-lyase [Serratia proteam...   460   e-127 
ref|ZP_01149311.1|  Pyruvate formate-lyase [Desulfotomaculum...   460   e-127 
ref|NP_720932.1|  formate acetyltransferase (pyruvate format...   460   e-127 
ref|ZP_00874721.1|  Pyruvate formate-lyase [Streptococcus su...   455   e-126 
ref|YP_857360.1|  pyruvate formate-lyase [Aeromonas hydrophi...   453   e-125 
ref|ZP_00833020.1|  COG1882: Pyruvate-formate lyase [Yersini...   452   e-125 
ref|YP_815753.1|  pyruvate formate-lyase [Streptococcus pneu...   450   e-124 
ref|NP_357826.1|  Formate acetyltransferase 3 [Streptococcus...   450   e-124 
ref|NP_344790.1|  formate acetyltransferase, putative [Strep...   450   e-124 
ref|ZP_00799753.1|  Formate C-acetyltransferase [Alkaliphilu...   440   e-121 
ref|ZP_01635825.1|  hypothetical protein CdifQ_03001213 [Clo...   439   e-121 
emb|CAJ67970.1|  glycerol dehydratase [Clostridium difficile...   437   e-121 
ref|NP_953150.1|  formate acetyltransferase [Geobacter sulfu...   437   e-121 
ref|ZP_01360821.1|  Formate C-acetyltransferase [Clostridium...   437   e-120 
ref|YP_855870.1|  pyruvate formate-lyase [Aeromonas hydrophi...   434   e-119 
ref|NP_782070.1|  formate acetyltransferase 2 [Clostridium t...   434   e-119 
ref|ZP_00801006.1|  Formate C-acetyltransferase [Alkaliphilu...   433   e-119 
ref|ZP_01352245.1|  Formate C-acetyltransferase [Clostridium...   430   e-118 
ref|YP_543898.1|  hypothetical protein UTI89_C4964 [Escheric...   428   e-118 
ref|ZP_00726050.1|  COG1882: Pyruvate-formate lyase [Escheri...   428   e-118 
ref|ZP_00800234.1|  Pyruvate formate-lyase [Alkaliphilus met...   425   e-117 
ref|ZP_01149160.1|  Formate C-acetyltransferase [Desulfotoma...   421   e-116 
ref|ZP_00800648.1|  Formate C-acetyltransferase [Alkaliphilu...   421   e-115 
ref|YP_389771.1|  Formate C-acetyltransferase [Desulfovibrio...   418   e-115 
ref|YP_065559.1|  Pyruvate formate-lyase 2 [Desulfotalea psy...   416   e-114 
ref|YP_356360.1|  pyruvate-formate lyase [Pelobacter carbino...   412   e-113 
ref|YP_051857.1|  putative formate acetyltransferase [Erwini...   412   e-113 
ref|YP_064352.1|  formate C-acetyltransferase [Desulfotalea ...   410   e-112 
ref|YP_521239.1|  pyruvate-formate lyase [Desulfitobacterium...   409   e-112 
ref|ZP_01371837.1|  pyruvate formate-lyase, PFL [Desulfitoba...   409   e-112 
ref|YP_389528.1|  Formate C-acetyltransferase [Desulfovibrio...   407   e-111 
emb|CAJ70179.1|  putative formate acetyltransferase [Clostri...   404   e-111 
ref|ZP_01633320.1|  hypothetical protein CdifQ_03003829 [Clo...   404   e-110 
ref|YP_182702.1|  pyruvate-formate lyase [Thermococcus kodak...   398   e-109 
ref|YP_965941.1|  Formate C-acetyltransferase [Desulfovibrio...   390   e-106 
ref|YP_012036.1|  formate acetyltransferase [Desulfovibrio v...   387   e-105 
ref|YP_387769.1|  Formate C-acetyltransferase [Desulfovibrio...   384   e-104 
gb|AAG55195.1|AE005263_4  putative pyruvate formate-lyase 2 ...   384   e-104 
ref|YP_066763.1|  similar to formate acetyltransferase [Desu...   384   e-104 
ref|ZP_01673292.1|  Formate C-acetyltransferase [Candidatus ...   377   e-102 
ref|ZP_01150365.1|  Formate C-acetyltransferase [Desulfotoma...   376   e-102 
ref|ZP_01371428.1|  pyruvate formate-lyase, PFL [Desulfitoba...   365   6e-99 
ref|YP_516649.1|  pyruvate-formate lyase [Desulfitobacterium...   363   3e-98 
ref|YP_011485.1|  formate acetyltransferase, putative [Desul...   348   9e-94 
ref|YP_966427.1|  Formate C-acetyltransferase [Desulfovibrio...   345   5e-93 
ref|YP_389544.1|  Formate C-acetyltransferase [Desulfovibrio...   318   6e-85 
ref|ZP_01674863.1|  Formate C-acetyltransferase [Candidatus ...   315   9e-84 
ref|YP_597484.1|  formate acetyltransferase [Streptococcus p...   311   7e-83 
dbj|GAA02540.1|  unnamed protein product [Pelotomaculum ther...   288   9e-76 
dbj|BAB34323.1|  hypothetical protein [Escherichia coli O157...   286   3e-75 
emb|CAJ66973.1|  4-hydroxyphenylacetate decarboxylase, catal...   277   2e-72 
emb|CAD65889.1|  HpdB protein [Clostridium difficile]             277   2e-72 
ref|ZP_01636619.1|  hypothetical protein CdifQ_03000177 [Clo...   241   1e-61 
ref|YP_101655.1|  putative pyruvate formate-lyase [Bacteroid...   241   2e-61 
ref|YP_213746.1|  putative formate acetyltransferase (pyruva...   240   3e-61 
gb|ABB05046.1|  4-hydroxyphenylacetate decarboxylase glycyl ...   236   4e-60 
gb|AAK50372.1|  alpha subunit of benzylsuccinate synthase [A...   224   2e-56 
dbj|BAC05501.1|  BssA [Thauera sp. DNT-1]                         223   3e-56 
gb|AAC38454.1|  TutD [Thauera aromatica]                          221   2e-55 
ref|ZP_01388334.1|  Formate C-acetyltransferase [Geobacter s...   219   4e-55 
ref|YP_158060.1|  alpha-Subunit of benzylsuccinate synthase ...   218   1e-54 
gb|EAG35428.1|  unknown [environmental sequence]                  214   2e-53 
emb|CAA05052.1|  benzylsuccinate synthase alpha subunit [Tha...   211   1e-52 
ref|YP_384498.1|  Formate C-acetyltransferase glycine radica...   211   2e-52 
dbj|BAD42366.1|  putative benzylsuccinate synthase alpha sub...   211   2e-52 
ref|ZP_01388342.1|  Formate C-acetyltransferase [Geobacter s...   209   7e-52 
gb|EAJ21838.1|  unknown [environmental sequence]                  201   1e-49 
ref|NP_811867.1|  formate acetyltransferase 2 [Bacteroides t...   189   4e-46 
ref|YP_519249.1|  putative pyruvate-formate lyase [Desulfito...   187   3e-45 
ref|YP_849619.1|  formate acetyltransferase [Listeria welshi...   175   1e-41 
ref|NP_470779.1|  pyruvate formate-lyase [Listeria innocua C...   174   2e-41 
ref|YP_014023.1|  formate acetyltransferase [Listeria monocy...   174   2e-41 
ref|NP_464931.1|  pyruvate formate-lyase [Listeria monocytog...   174   2e-41 
ref|NP_275489.1|  formate acetyltransferase 2 [Methanothermo...   173   3e-41 
ref|YP_079294.1|  putative formate C-acetyltransferase [Baci...   169   5e-40 
emb|CAF04129.1|  pyruvate formate-lyase [Chlamydomonas reinh...   167   3e-39 
ref|ZP_01150368.1|  Formate C-acetyltransferase [Desulfotoma...   165   1e-38 
ref|YP_878524.1|  formate acetyltransferase [Clostridium nov...   164   1e-38 
ref|YP_073944.1|  pyruvate formate-lyase [Symbiobacterium th...   164   2e-38 
ref|NP_681780.1|  formate acetyltransferase [Thermosynechoco...   163   3e-38 
ref|NP_830328.1|  Formate acetyltransferase [Bacillus cereus...   163   4e-38 
ref|ZP_01181225.1|  Formate acetyltransferase [Bacillus cere...   163   4e-38 
sp|Q46266|PFL_CLOPA  Formate acetyltransferase (Pyruvate for...   162   6e-38 
gb|EAY44467.1|  formate acetyltransferase [Bacillus coagulan...   162   9e-38 
ref|ZP_00799914.1|  Formate acetyltransferase [Alkaliphilus ...   162   9e-38 
ref|ZP_00237990.1|  formate acetyltransferase [Bacillus cere...   161   2e-37 
ref|ZP_01149762.1|  Formate acetyltransferase [Desulfotomacu...   160   2e-37 
ref|NP_976890.1|  formate acetyltransferase [Bacillus cereus...   160   3e-37 
ref|ZP_01183234.1|  Formate acetyltransferase [Bacillus weih...   160   3e-37 
ref|YP_034774.1|  formate C-acetyltransferase (formate acety...   160   4e-37 
ref|YP_082029.1|  formate C-acetyltransferase (formate acety...   160   4e-37 
ref|NP_843045.1|  formate acetyltransferase [Bacillus anthra...   160   4e-37 
ref|YP_893348.1|  formate acetyltransferase [Bacillus thurin...   159   5e-37 
ref|YP_698491.1|  formate acetyltransferase [Clostridium per...   159   5e-37 
ref|NP_562069.1|  formate acetyltransferase [Clostridium per...   159   5e-37 
ref|ZP_00740300.1|  Formate acetyltransferase [Bacillus thur...   159   5e-37 
ref|ZP_00134205.1|  COG1882: Pyruvate-formate lyase [Actinob...   159   5e-37 
ref|YP_476506.1|  formate acetyltransferase [Synechococcus s...   159   6e-37 
ref|ZP_01573978.1|  formate acetyltransferase [Clostridium c...   159   8e-37 
ref|ZP_01388034.1|  Formate C-acetyltransferase [Geobacter s...   157   2e-36 
ref|ZP_01636259.1|  hypothetical protein CdifQ_03000835 [Clo...   157   2e-36 
ref|YP_473958.1|  formate acetyltransferase [Synechococcus s...   157   2e-36 
ref|ZP_00911783.1|  Formate acetyltransferase [Clostridium b...   157   2e-36 
emb|CAJ67593.1|  formate acetyltransferase [Clostridium diff...   157   2e-36 
ref|NP_873480.1|  formate acetyltransferase [Haemophilus duc...   157   3e-36 
ref|YP_597483.1|  formate acetyltransferase [Streptococcus p...   156   4e-36 
ref|ZP_00538854.1|  Formate acetyltransferase [Exiguobacteri...   156   5e-36 
ref|NP_347616.1|  Pyruvate-formate lyase [Clostridium acetob...   155   9e-36 
ref|YP_753731.1|  Formate C-acetyltransferase [Syntrophomona...   155   9e-36 
gb|AAF18275.1|  formate acetyltransferase [Zymomonas mobilis]     155   1e-35 
ref|NP_370750.1|  formate acetyltransferase [Staphylococcus ...   154   2e-35 
ref|YP_087593.1|  PflD protein [Mannheimia succiniciproducen...   154   2e-35 
ref|ZP_01189783.1|  Formate acetyltransferase [Halothermothr...   154   3e-35 
ref|ZP_01667164.1|  formate acetyltransferase [Thermosinus c...   153   3e-35 
ref|YP_536763.1|  Formate acetyltransferase [Lactobacillus s...   153   3e-35 
ref|YP_098622.1|  formate acetyltransferase [Bacteroides fra...   153   3e-35 
ref|ZP_01590023.1|  formate acetyltransferase [Enterobacter ...   153   4e-35 
ref|YP_163305.1|  formate acetyltransferase [Zymomonas mobil...   153   4e-35 
ref|YP_206100.1|  formate acetyltransferase [Vibrio fischeri...   152   6e-35 
ref|ZP_00701192.1|  COG1882: Pyruvate-formate lyase [Escheri...   152   6e-35 
ref|NP_813649.1|  formate acetyltransferase [Bacteroides the...   152   7e-35 
ref|YP_454668.1|  formate acetyltransferase 1 [Sodalis gloss...   152   7e-35 
ref|YP_530963.1|  formate acetyltransferase [Rhodopseudomona...   152   7e-35 
ref|YP_532844.1|  formate acetyltransferase [Rhodopseudomona...   152   1e-34 
ref|NP_755739.1|  Keto-acid formate acetyltransferase [Esche...   151   1e-34 
ref|NP_457629.1|  probable formate acetyltransferase [Salmon...   151   1e-34 
ref|ZP_01115043.1|  formate acetyltransferase [Reinekea sp. ...   151   1e-34 
ref|YP_542526.1|  Keto-acid formate acetyltransferase [Esche...   151   2e-34 
ref|YP_404793.1|  probable formate acetyltransferase 3 [Shig...   151   2e-34 
ref|YP_152253.1|  probable formate acetyltransferase [Salmon...   151   2e-34 
ref|YP_428082.1|  Formate acetyltransferase [Rhodospirillum ...   151   2e-34 
ref|ZP_00724752.1|  COG1882: Pyruvate-formate lyase [Escheri...   151   2e-34 
ref|NP_462155.1|  pyruvate formate-lyase 4/2-ketobutyrate fo...   150   2e-34 
ref|ZP_00510887.1|  Formate acetyltransferase [Clostridium t...   150   2e-34 
ref|YP_409319.1|  probable formate acetyltransferase 3 [Shig...   150   3e-34 
ref|YP_312082.1|  probable formate acetyltransferase 3 [Shig...   150   3e-34 
ref|NP_708918.1|  probable formate acetyltransferase 3 [Shig...   150   3e-34 
ref|YP_026205.1|  pyruvate formate-lyase 4/2-ketobutyrate fo...   150   3e-34 
gb|AAM34597.1|AF441130_1  benzylsuccinate synthase alpha sub...   150   4e-34 
ref|ZP_00911781.1|  Formate acetyltransferase [Clostridium b...   150   4e-34 
ref|ZP_00735753.1|  COG1882: Pyruvate-formate lyase [Escheri...   150   4e-34 
ref|ZP_00833599.1|  COG1882: Pyruvate-formate lyase [Yersini...   150   4e-34 
ref|ZP_00698762.1|  COG1882: Pyruvate-formate lyase [Shigell...   150   4e-34 
gb|EAY49539.1|  formate acetyltransferase [Escherichia coli B]    149   5e-34 
ref|ZP_01573891.1|  formate acetyltransferase [Clostridium c...   149   5e-34 
ref|YP_690516.1|  probable formate acetyltransferase 3 [Shig...   149   6e-34 
emb|CAA76352.1|  formate C-acetyltransferase [Piromyces sp. E2]   149   6e-34 
ref|YP_218174.1|  pyruvate formate-lyase 4/ 2-ketobutyrate f...   149   6e-34 
ref|NP_289686.1|  probable formate acetyltransferase 3 [Esch...   149   6e-34 
ref|NP_928902.1|  formate acetyltransferase I (pyruvate form...   149   8e-34 
ref|YP_001004717.1|  keto-acid formate acetyltransferase [Ye...   148   1e-33 
ref|ZP_00834662.1|  COG1882: Pyruvate-formate lyase [Yersini...   147   2e-33 
ref|ZP_01536329.1|  formate acetyltransferase [Serratia prot...   147   3e-33 
ref|YP_782018.1|  formate acetyltransferase [Rhodopseudomona...   147   3e-33 
ref|YP_719348.1|  formate acetyltransferase [Haemophilus som...   147   3e-33 
ref|YP_856472.1|  formate acetyltransferase [Aeromonas hydro...   146   4e-33 
ref|YP_001005827.1|  formate acetyltransferase 1 [Yersinia e...   146   5e-33 
ref|NP_763769.1|  formate acetyltransferase [Staphylococcus ...   146   5e-33 
ref|YP_189914.1|  formate acetyltransferase [Staphylococcus ...   145   7e-33 
ref|ZP_00830378.1|  COG1882: Pyruvate-formate lyase [Yersini...   145   7e-33 
ref|ZP_00826899.1|  COG1882: Pyruvate-formate lyase [Yersini...   145   7e-33 
ref|ZP_00822360.1|  COG1882: Pyruvate-formate lyase [Yersini...   145   7e-33 
ref|ZP_00132347.1|  COG1882: Pyruvate-formate lyase [Haemoph...   145   7e-33 
gb|AAS06904.1|  pyruvate formate lyase [Neocallimastix front...   145   9e-33 
ref|ZP_01451264.1|  formate C-acetyltransferase [Mariprofund...   144   2e-32 
ref|NP_245012.1|  PflB [Pasteurella multocida subsp. multoci...   144   2e-32 
ref|NP_901082.1|  formate C-acetyltransferase [Chromobacteri...   144   3e-32 
ref|NP_670091.1|  formate acetyltransferase 1 [Yersinia pest...   143   3e-32 
ref|NP_404976.1|  formate acetyltransferase 1 [Yersinia pest...   143   3e-32 
ref|YP_215914.1|  pyruvate formate lyase I, induced anaerobi...   143   5e-32 
ref|NP_455460.1|  formate acetyltransferase 1 [Salmonella en...   143   5e-32 
gb|ABM92936.1|  benzylsuccinate synthase alpha subunit [Geob...   142   6e-32 
gb|ABM92938.1|  benzylsuccinate synthase alpha subunit [Geob...   142   6e-32 
ref|YP_050688.1|  formate acetyltransferase [Erwinia carotov...   142   6e-32 
ref|ZP_01233506.1|  formate acetyltransferase [Vibrio angust...   142   8e-32 
ref|ZP_01262811.1|  formate acetyltransferase [Vibrio algino...   141   1e-31 
ref|YP_576212.1|  formate acetyltransferase [Nitrobacter ham...   141   1e-31 
ref|NP_438348.1|  formate acetyltransferase 1-like protein [...   141   1e-31 
ref|ZP_00154701.2|  COG1882: Pyruvate-formate lyase [Haemoph...   141   1e-31 
ref|ZP_00716415.1|  COG1882: Pyruvate-formate lyase [Escheri...   141   2e-31 
gb|AAD52103.1|AF108502_1  pyruvate formate-lyase Pfl [Aeromo...   140   2e-31 
pdb|2PFL|A  Chain A, Crystal Structure Of Pfl From E.Coli >g...   140   2e-31 
ref|NP_415423.1|  pyruvate formate lyase I [Escherichia coli...   140   2e-31 
ref|ZP_01588955.1|  formate acetyltransferase [Enterobacter ...   140   3e-31 
ref|ZP_01064750.1|  formate acetyltransferase [Vibrio sp. ME...   140   3e-31 
ref|ZP_00698348.1|  COG1882: Pyruvate-formate lyase [Shigell...   140   3e-31 
ref|NP_286778.1|  formate acetyltransferase 1 [Escherichia c...   140   4e-31 
ref|ZP_00718775.1|  COG1882: Pyruvate-formate lyase [Escheri...   140   4e-31 
ref|NP_706821.1|  formate acetyltransferase 1 [Shigella flex...   139   5e-31 
ref|ZP_01159295.1|  Formate acetyltransferase [Photobacteriu...   139   5e-31 
ref|ZP_00920601.1|  COG1882: Pyruvate-formate lyase [Shigell...   139   5e-31 
ref|ZP_00992496.1|  formate acetyltransferase [Vibrio splend...   139   7e-31 
ref|ZP_01220863.1|  putative formate acetyltransferase [Phot...   139   9e-31 
ref|YP_285309.1|  Formate acetyltransferase [Dechloromonas a...   138   1e-30 
pdb|1CM5|A  Chain A, Crystal Structure Of C418a,C419a Mutant...   138   1e-30 
ref|NP_231500.1|  formate acetyltransferase [Vibrio cholerae...   137   2e-30 
ref|ZP_01476030.1|  hypothetical protein VEx2w_02001394 [Vib...   137   2e-30 
ref|ZP_00756626.1|  COG1882: Pyruvate-formate lyase [Vibrio ...   137   2e-30 
ref|ZP_01677078.1|  formate acetyltransferase [Vibrio choler...   137   2e-30 
ref|YP_944593.1|  formate acetyltransferase [Psychromonas in...   137   2e-30 
ref|ZP_01260420.1|  formate acetyltransferase [Vibrio algino...   137   2e-30 
ref|ZP_01541719.1|  formate acetyltransferase [Shewanella wo...   137   3e-30 
gb|AAA57918.1|  ORF_f746 [Escherichia coli]                       136   4e-30 
ref|NP_603169.1|  Formate acetyltransferase [Fusobacterium n...   136   4e-30 
ref|ZP_00144711.1|  Formate acetyltransferase [Fusobacterium...   136   4e-30 
ref|YP_130924.1|  putative formate acetyltransferase [Photob...   136   6e-30 
ref|ZP_01483064.1|  hypothetical protein VchoR_02001028 [Vib...   136   6e-30 
ref|ZP_01215356.1|  formate acetyltransferase 1 [Psychromona...   135   7e-30 
ref|NP_797373.1|  formate acetyltransferase [Vibrio parahaem...   135   7e-30 
ref|ZP_00604736.1|  Formate acetyltransferase [Enterococcus ...   135   7e-30 
ref|ZP_01235148.1|  formate acetyltransferase [Vibrio angust...   134   2e-29 
ref|YP_204973.1|  formate acetyltransferase [Vibrio fischeri...   134   2e-29 
ref|NP_760959.1|  Formate acetyltransferase [Vibrio vulnific...   134   3e-29 
ref|XP_001228851.1|  hypothetical protein CHGG_02335 [Chaeto...   133   4e-29 
ref|YP_927375.1|  Formate C-acetyltransferase [Shewanella am...   133   4e-29 
ref|ZP_00583942.1|  Formate acetyltransferase [Shewanella ba...   133   4e-29 
ref|NP_786563.1|  formate C-acetyltransferase [Lactobacillus...   133   5e-29 
emb|CAL52534.1|  formate acetyltransferase (ISS) [Ostreococc...   132   6e-29 
ref|ZP_00838821.1|  Formate acetyltransferase [Shewanella sp...   131   1e-28 
ref|YP_563409.1|  formate acetyltransferase [Shewanella deni...   131   2e-28 
gb|EAK68528.1|  unknown [environmental sequence]                  130   2e-28 
ref|ZP_01605299.1|  formate acetyltransferase [Shewanella pe...   130   2e-28 
ref|YP_869195.1|  formate acetyltransferase [Shewanella sp. ...   130   2e-28 
ref|NP_815326.1|  formate acetyltransferase [Enterococcus fa...   130   4e-28 
gb|ABM92939.1|  benzylsuccinate synthase alpha subunit [sulf...   129   7e-28 
ref|YP_395585.1|  Formate C-acetyltransferase (Pyruvate form...   129   7e-28 
ref|ZP_00814263.1|  Formate acetyltransferase [Shewanella pu...   128   1e-27 
ref|YP_806630.1|  Pyruvate-formate lyase [Lactobacillus case...   127   2e-27 
ref|NP_718482.1|  formate acetyltransferase [Shewanella onei...   127   2e-27 
ref|YP_733629.1|  formate acetyltransferase [Shewanella sp. ...   127   2e-27 
ref|YP_737616.1|  formate acetyltransferase [Shewanella sp. ...   127   3e-27 
gb|EAJ33078.1|  unknown [environmental sequence]                  127   3e-27 
ref|YP_751156.1|  formate acetyltransferase [Shewanella frig...   127   3e-27 
ref|ZP_01150038.1|  formate acetyltransferase [Desulfotomacu...   121   1e-25 
ref|ZP_01160203.1|  formate acetyltransferase [Photobacteriu...   120   4e-25 
ref|NP_519667.1|  hypothetical protein RSc1546 [Ralstonia so...   119   9e-25 
ref|ZP_00944923.1|  Formate acetyltransferase [Ralstonia sol...   118   2e-24 
ref|ZP_00517067.1|  Formate C-acetyltransferase [Crocosphaer...   115   1e-23 
ref|ZP_01352739.1|  formate acetyltransferase [Clostridium p...   115   1e-23 
gb|ABM92935.1|  benzylsuccinate synthase alpha subunit [Desu...   111   2e-22 
gb|EAG02837.1|  unknown [environmental sequence]                  110   3e-22 
sp|P37836|PFL_CHLRE  Formate acetyltransferase (Pyruvate for...   108   1e-21 
gb|EAH39453.1|  unknown [environmental sequence]                  105   1e-20 
gb|EAI39905.1|  unknown [environmental sequence]                  100   3e-19 
ref|NP_696127.1|  formate acetyltransferase [Bifidobacterium...    96   6e-18 
gb|AAG55196.1|AE005263_5  orf; Unknown function [Escherichia...    96   6e-18 
ref|ZP_00121554.2|  COG1882: Pyruvate-formate lyase [Bifidob...    96   6e-18 
ref|YP_909855.1|  formate acetyltransferase [Bifidobacterium...    94   4e-17 
gb|EAH21988.1|  unknown [environmental sequence]                   92   2e-16 
gb|EAG80484.1|  unknown [environmental sequence]                   91   3e-16 
gb|EAH22348.1|  unknown [environmental sequence]                   87   5e-15 
gb|AAY34226.1|  glycerol dehydratase [Clostridium sp. IBUN 22A]    80   4e-13 
pdb|1QHM|A  Chain A, Escherichia Coli Pyruvate Formate Lyase...    80   6e-13 
ref|NP_720850.1|  pyruvate formate-lyase [Streptococcus muta...    76   7e-12 
gb|EAH13415.1|  unknown [environmental sequence]                   75   1e-11 
dbj|BAA09085.1|  Pyruvate formate-lyase [Streptococcus mutans]     73   6e-11 
gb|ABM66441.1|  benzylsuccinate synthase [uncultured bacterium]    73   8e-11 
ref|NP_266820.1|  pyruvate-formate lyase [Lactococcus lactis...    72   1e-10 
gb|ABM66440.1|  benzylsuccinate synthase [uncultured bacterium]    70   4e-10 
sp|O32799|PFL_LACLC  Formate acetyltransferase (Pyruvate for...    70   4e-10 
ref|YP_808678.1|  Pyruvate-formate lyase [Lactococcus lactis...    70   6e-10 
gb|EAJ06673.1|  unknown [environmental sequence]                   69   1e-09 
gb|AAA92439.1|  formate acetyltransferase                          69   1e-09 
ref|NP_736206.1|  hypothetical protein gbs1772 [Streptococcu...    69   1e-09 
ref|NP_688717.1|  formate acetyltransferase [Streptococcus a...    69   1e-09 
ref|NP_665400.1|  putative pyruvate formate-lyase [Streptoco...    67   3e-09 
ref|YP_599245.1|  Formate acetyltransferase [Streptococcus p...    67   4e-09 
ref|YP_060899.1|  Formate acetyltransferase [Streptococcus p...    67   4e-09 
ref|NP_269846.1|  putative pyruvate formate-lyase [Streptoco...    67   4e-09 
ref|ZP_00874531.1|  Formate acetyltransferase [Streptococcus...    66   9e-09 
ref|YP_850140.1|  formate acetyltransferase [Listeria welshi...    64   4e-08 
ref|NP_471365.1|  pflA [Listeria innocua Clip11262] >gi|1641...    64   5e-08 
gb|ABM92934.1|  benzylsuccinate synthase alpha subunit [Desu...    63   6e-08 
gb|ABM91877.1|  benzylsuccinate synthase alpha subunit [uncu...    63   6e-08 
ref|YP_014539.1|  formate acetyltransferase [Listeria monocy...    62   1e-07 
ref|NP_465441.1|  hypothetical protein lmo1917 [Listeria mon...    62   1e-07 
ref|ZP_01352737.1|  Formate C-acetyltransferase glycine radi...    61   3e-07 
dbj|BAA28614.1|  pyruvate formate-lyase [Streptococcus bovis]      61   3e-07 
gb|ABM91880.1|  benzylsuccinate synthase alpha subunit [uncu...    60   7e-07 
gb|ABM91881.1|  benzylsuccinate synthase alpha subunit [uncu...    59   1e-06 
gb|ABM91885.1|  benzylsuccinate synthase alpha subunit [uncu...    58   3e-06 
emb|CAA04876.1|  keto acid formate-lyase [Escherichia coli W...    57   3e-06 
gb|ABM91883.1|  benzylsuccinate synthase alpha subunit [uncu...    57   4e-06 
gb|ABM91884.1|  benzylsuccinate synthase alpha subunit [uncu...    57   6e-06 
gb|ABM91882.1|  benzylsuccinate synthase alpha subunit [uncu...    57   6e-06 
gb|EAI72901.1|  unknown [environmental sequence]                   56   1e-05 
ref|YP_140075.1|  pyruvate formate-lyase [Streptococcus ther...    55   2e-05 
gb|EAG86458.1|  unknown [environmental sequence]                   55   2e-05 
gb|EAE34872.1|  unknown [environmental sequence]                   55   2e-05 
gb|ABM91878.1|  benzylsuccinate synthase alpha subunit [uncu...    52   1e-04 
ref|YP_006884.1|  putative acetyltransferase-related protein...    52   1e-04 
emb|CAE53183.1|  hypothetical protein [Enterobacteria phage ...    52   1e-04 
emb|CAE53209.1|  hypothetical protein [Bacteriophage 5]            52   1e-04 
ref|YP_205498.1|  formate acetyltransferase [Vibrio fischeri...    51   2e-04 
ref|ZP_01236398.1|  putative formate acetyl transferase-rela...    51   3e-04 
ref|ZP_01159094.1|  putative formate acetyl transferase-rela...    51   3e-04 
ref|NP_668605.1|  formate acetyltransferase [Yersinia pestis...    50   4e-04 
ref|NP_406222.1|  hypothetical protein YPO2705 [Yersinia pes...    50   4e-04 
gb|ABG89173.1|  hypothetical protein mh0741 [Mannheimia haem...    50   7e-04 
gb|ABM91894.1|  benzylsuccinate synthase alpha subunit [uncu...    49   9e-04 
ref|YP_051377.1|  hypothetical protein ECA3288 [Erwinia caro...    49   9e-04 
ref|YP_942707.1|  formate C-acetyltransferase glycine radica...    49   0.001 
ref|ZP_01217096.1|  threonine synthase [Psychromonas sp. CNP...    49   0.001 
gb|AAR90897.1|  Vs.6 conserved hypothetical protein [Aeromon...    49   0.001 
ref|YP_001005336.1|  hypothetical protein YE1003 [Yersinia e...    49   0.002 
gb|ABM26901.1|  hypothetical protein [Serratia marcescens]         49   0.002 
ref|ZP_01591129.1|  formate C-acetyltransferase glycine radi...    49   0.002 
ref|ZP_01535962.1|  formate C-acetyltransferase glycine radi...    49   0.002 
ref|YP_803062.1|  hypothetical protein RB32ORF120c [Bacterio...    49   0.002 
ref|YP_690043.1|  putative formate acetyltransferase [Shigel...    49   0.002 
ref|YP_404356.1|  putative formate acetyltransferase [Shigel...    49   0.002 
ref|NP_754984.1|  Protein yfiD [Escherichia coli CFT073] >gi...    49   0.002 
ref|YP_455476.1|  hypothetical protein SG1796 [Sodalis gloss...    49   0.002 
ref|NP_838151.1|  putative formate acetyltransferase [Shigel...    49   0.002 
ref|NP_289137.1|  putative formate acetyltransferase [Escher...    49   0.002 
ref|NP_457121.1|  hypothetical protein STY2839 [Salmonella e...    49   0.002 
ref|NP_245001.1|  hypothetical protein PM0064 [Pasteurella m...    49   0.002 
sp|P18953|GRCA_SERLI  Autonomous glycyl radical cofactor >gi...    49   0.002 
ref|ZP_01065704.1|  formate acetyl transferase-related prote...    49   0.002 
ref|ZP_00992008.1|  formate acetyltransferase [Vibrio splend...    49   0.002 
ref|ZP_00833850.1|  COG3445: Acid-induced glycyl radical enz...    49   0.002 
ref|ZP_00830274.1|  COG3445: Acid-induced glycyl radical enz...    49   0.002 
ref|ZP_00827174.1|  COG3445: Acid-induced glycyl radical enz...    49   0.002 
ref|ZP_00822631.1|  COG3445: Acid-induced glycyl radical enz...    49   0.002 
ref|ZP_00721437.1|  COG3445: Acid-induced glycyl radical enz...    49   0.002 
ref|ZP_00132434.1|  COG3445: Acid-induced glycyl radical enz...    49   0.002 
ref|NP_311472.1|  putative formate acetyltransferase [Escher...    49   0.002 
ref|ZP_01221164.1|  putative formate acetyl transferase-rela...    48   0.002 
ref|NP_861810.1|  Vs.6 conserved hypothetical protein [Enter...    48   0.002 
ref|YP_239057.1|  Vs.6 [Enterobacteria phage RB43] >gi|62288...    48   0.002 
sp|Q6LUP6|GRCA_PHOPR  Autonomous glycyl radical cofactor           48   0.002 
ref|YP_128781.1|  putative formate acetyl transferase-relate...    48   0.002 
ref|NP_873546.1|  Putative formate acetyltransferase [Haemop...    48   0.002 
ref|NP_049730.1|  Vs.6 conserved hypothetical protein [Enter...    48   0.002 
gb|EAY40095.1|  glycine radical signiture protein [Vibrio ch...    48   0.003 
ref|NP_933446.1|  acid-induced glycyl radical enzyme [Vibrio...    48   0.003 
ref|NP_796876.1|  formate acetyl transferase-related protein...    48   0.003 
ref|NP_759532.1|  Acid-induced glycyl radical enzyme [Vibrio...    48   0.003 
ref|ZP_01261451.1|  formate acetyl transferase-related prote...    48   0.003 
ref|ZP_01481404.1|  hypothetical protein VchoR_02002712 [Vib...    48   0.003 
ref|NP_231991.1|  formate acetyl transferase-related protein...    48   0.003 
emb|CAI05898.1|  putative formate acetyltransferase [Orpinom...    47   0.003 
ref|YP_247680.1|  conserved hypothetical acid-induced glycyl...    47   0.003 
ref|YP_087564.1|  hypothetical protein MS0372 [Mannheimia su...    47   0.003 
ref|NP_438190.1|  hypothetical protein HI0017 [Haemophilus i...    47   0.003 
gb|EAJ19896.1|  unknown [environmental sequence]                   47   0.004 
ref|YP_857643.1|  autonomous glycyl radical cofactor [Aeromo...    47   0.004 
ref|YP_238845.1|  similar to NP_932473.1 [Aeromonas phage 31...    47   0.004 
ref|NP_932473.1|  Vs.6 [Bacteriophage 44RR2.8t] >gi|34732899...    47   0.004 
ref|ZP_00135653.1|  COG3445: Acid-induced glycyl radical enz...    47   0.004 
gb|ABM91903.1|  benzylsuccinate synthase alpha subunit [uncu...    45   0.017 
gb|ABM91899.1|  benzylsuccinate synthase alpha subunit [uncu...    45   0.017 
gb|ABM91895.1|  benzylsuccinate synthase alpha subunit [uncu...    45   0.022 
gb|ABM91897.1|  benzylsuccinate synthase alpha subunit [uncu...    45   0.022 
gb|ABM91905.1|  benzylsuccinate synthase alpha subunit [uncu...    45   0.022 
gb|ABM91896.1|  benzylsuccinate synthase alpha subunit [uncu...    45   0.022 
ref|ZP_00516106.1|  Formate C-acetyltransferase [Crocosphaer...    45   0.022 
gb|EAD13898.1|  unknown [environmental sequence]                   44   0.029 
gb|ABM91908.1|  benzylsuccinate synthase alpha subunit [uncu...    44   0.029 
gb|ABM91888.1|  benzylsuccinate synthase alpha subunit [uncu...    44   0.029 
gb|ABM91898.1|  benzylsuccinate synthase alpha subunit [uncu...    44   0.038 
ref|NP_943917.1|  Vs.6 conserved hypothetical protein [Bacte...    44   0.038 
ref|NP_891670.1|  Vs.6 conserved hypothetical protein [Enter...    44   0.038 
gb|ABM91893.1|  benzylsuccinate synthase alpha subunit [uncu...    44   0.049 

>ref|NP_418386.1| predicted formate acetyltransferase 2 (pyruvate formate lyase II)
           [Escherichia coli K12]
 ref|AP_003859.1| predicted formate acetyltransferase 2 [Escherichia coli W3110]
 sp|P32674|PFLD_ECOLI Formate acetyltransferase 2 (Pyruvate formate-lyase 2)
 gb|AAC43057.1| ORF_o765 [Escherichia coli]
 gb|AAC76933.1| predicted formate acetyltransferase 2 (pyruvate formate lyase II)
           [Escherichia coli K12]
 dbj|BAE77360.1| predicted formate acetyltransferase 2 [Escherichia coli W3110]
          Length = 765

 Score = 1522 bits (3941), Expect = 0.0
 Identities = 765/765 (100%), Positives = 765/765 (100%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00707894.1| COG1882: Pyruvate-formate lyase [Escherichia coli HS]
 ref|ZP_00924841.1| COG1882: Pyruvate-formate lyase [Escherichia coli 101-1]
 gb|EAY48782.1| pyruvate formate-lyase [Escherichia coli B]
          Length = 765

 Score = 1517 bits (3927), Expect = 0.0
 Identities = 762/765 (99%), Positives = 764/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VF+QQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFDQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00736216.1| COG1882: Pyruvate-formate lyase [Escherichia coli 53638]
          Length = 765

 Score = 1516 bits (3924), Expect = 0.0
 Identities = 761/765 (99%), Positives = 764/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALF+NTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFSNTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VF+QQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFDQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00701955.1| COG1882: Pyruvate-formate lyase [Escherichia coli E24377A]
          Length = 765

 Score = 1516 bits (3924), Expect = 0.0
 Identities = 762/765 (99%), Positives = 764/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICL+ENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLYENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|NP_709751.1| formate acetyltransferase 2 [Shigella flexneri 2a str. 301]
 ref|NP_838933.1| formate acetyltransferase 2 [Shigella flexneri 2a str. 2457T]
 ref|YP_691327.1| formate acetyltransferase 2 [Shigella flexneri 5 str. 8401]
 gb|AAN45458.1| formate acetyltransferase 2 [Shigella flexneri 2a str. 301]
 gb|AAP18744.1| formate acetyltransferase 2 [Shigella flexneri 2a str. 2457T]
 gb|ABF06022.1| formate acetyltransferase 2 [Shigella flexneri 5 str. 8401]
          Length = 765

 Score = 1514 bits (3921), Expect = 0.0
 Identities = 761/765 (99%), Positives = 761/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLR FTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRVFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00714537.1| COG1882: Pyruvate-formate lyase [Escherichia coli B7A]
 ref|ZP_00729526.1| COG1882: Pyruvate-formate lyase [Escherichia coli E22]
          Length = 765

 Score = 1513 bits (3917), Expect = 0.0
 Identities = 760/765 (99%), Positives = 762/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00722395.1| COG1882: Pyruvate-formate lyase [Escherichia coli E110019]
          Length = 765

 Score = 1513 bits (3916), Expect = 0.0
 Identities = 760/765 (99%), Positives = 761/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELL IAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLIIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00709599.1| COG1882: Pyruvate-formate lyase [Escherichia coli B171]
          Length = 765

 Score = 1511 bits (3911), Expect = 0.0
 Identities = 759/765 (99%), Positives = 761/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKG GHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGPGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|YP_543485.1| formate acetyltransferase 2 [Escherichia coli UTI89]
 ref|YP_859543.1| putative formate acetyltransferase 2 [Escherichia coli APEC O1]
 gb|ABE09954.1| formate acetyltransferase 2 [Escherichia coli UTI89]
 gb|ABJ03419.1| putative formate acetyltransferase 2 [Escherichia coli APEC O1]
          Length = 765

 Score = 1509 bits (3907), Expect = 0.0
 Identities = 756/765 (98%), Positives = 762/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVI+RRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVIMRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAA+CTD QRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAASCTDGQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           +F+QQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 IFDQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00921230.1| COG1882: Pyruvate-formate lyase [Shigella dysenteriae 1012]
          Length = 765

 Score = 1507 bits (3901), Expect = 0.0
 Identities = 758/765 (99%), Positives = 760/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFAN  EISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANICEISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGEDAAFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDAAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPE EKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEDEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00724288.1| COG1882: Pyruvate-formate lyase [Escherichia coli F11]
 ref|YP_672021.1| formate acetyltransferase 2 [Escherichia coli 536]
 gb|ABG72120.1| formate acetyltransferase 2 [Escherichia coli 536]
          Length = 765

 Score = 1507 bits (3901), Expect = 0.0
 Identities = 755/765 (98%), Positives = 761/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVI+RRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVIMRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAA+CTD  RREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAASCTDGPRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           +F+QQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 IFDQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|ZP_00696787.1| COG1882: Pyruvate-formate lyase [Shigella boydii BS512]
 ref|YP_410249.1| formate acetyltransferase 2 [Shigella boydii Sb227]
 gb|ABB68421.1| formate acetyltransferase 2 [Shigella boydii Sb227]
          Length = 765

 Score = 1505 bits (3897), Expect = 0.0
 Identities = 757/765 (98%), Positives = 759/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYA LAETMAANCTDAQRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAVLAETMAANCTDAQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQD QGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDEQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TL EAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLWEAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|NP_756764.1| Formate acetyltransferase 2 [Escherichia coli CFT073]
 gb|AAN83338.1|AE016770_138 Formate acetyltransferase 2 [Escherichia coli CFT073]
          Length = 765

 Score = 1505 bits (3896), Expect = 0.0
 Identities = 754/765 (98%), Positives = 760/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVI+RRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVIMRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAA+CTD  RREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAASCTDGPRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           +F+QQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 IFDQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|NP_290588.1| formate acetyltransferase 2 [Escherichia coli O157:H7 EDL933]
 ref|NP_312907.1| formate acetyltransferase 2 [Escherichia coli O157:H7 str. Sakai]
 gb|AAG59153.1|AE005626_8 formate acetyltransferase 2 [Escherichia coli O157:H7 EDL933]
 dbj|BAB38303.1| formate acetyltransferase 2 [Escherichia coli O157:H7 str. Sakai]
          Length = 765

 Score = 1504 bits (3895), Expect = 0.0
 Identities = 756/765 (98%), Positives = 760/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLLKEL QFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELGQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAA+CTDAQRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAASCTDAQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VF+QQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEV NISAELLRHYCKE
Sbjct: 541 VFDQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVGNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|YP_405222.1| formate acetyltransferase 2 [Shigella dysenteriae Sd197]
 gb|ABB63731.1| formate acetyltransferase 2 [Shigella dysenteriae Sd197]
          Length = 765

 Score = 1498 bits (3879), Expect = 0.0
 Identities = 754/765 (98%), Positives = 758/765 (99%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MTNRISRLKTALFANTREISLERA LYTASHRQTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTNRISRLKTALFANTREISLERARLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVK RAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE
Sbjct: 61  EELIAGNRTVKLRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAAT+TQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC
Sbjct: 121 KRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           QQQPENHFYQAALLLLEASQKHILRYAELAETMAA+CTDAQRREELLTIAEISRHNA+HK
Sbjct: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAASCTDAQRREELLTIAEISRHNAEHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ SLTQGED AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFLMKTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV
Sbjct: 361 NLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VF+QQRLSFDELLSVLKANFAT EGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE
Sbjct: 541 VFDQQRLSFDELLSVLKANFATLEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQD QGPTA
Sbjct: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDTQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|NP_462994.1| putative pyruvate formate lyase II [Salmonella typhimurium LT2]
 gb|AAL22953.1| putative pyruvate formate lyase II [Salmonella typhimurium LT2]
          Length = 765

 Score = 1409 bits (3647), Expect = 0.0
 Identities = 707/765 (92%), Positives = 730/765 (95%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MT+RI RLK ALF N REISLERALLYTASH+QTEGEPVILRRAKATAYILEHVEISIRD
Sbjct: 1   MTHRIQRLKAALFQNHREISLERALLYTASHQQTEGEPVILRRAKATAYILEHVEISIRD 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELIAGNRTVKPRAGIMSPEMDPYWLL ELD+FPTRPQDRF ISEEDKR+YRE LFPYWE
Sbjct: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLNELDRFPTRPQDRFDISEEDKRLYREVLFPYWE 120

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           KRSMKDFINGQMTDEVKAA +TQIFSINQTDKGQGHIIIDYPRLLN+GLGEL AQM+  C
Sbjct: 121 KRSMKDFINGQMTDEVKAAVSTQIFSINQTDKGQGHIIIDYPRLLNNGLGELAAQMRARC 180

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
           +QQPEN FYQAALLLLEASQ+HILRYA LAE  A  C DA+RR+ELLTIA  SRHNAQHK
Sbjct: 181 EQQPENDFYQAALLLLEASQRHILRYAVLAEQQAERCPDARRRQELLTIAANSRHNAQHK 240

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESL 300
           PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG+D AFLKELLESL
Sbjct: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGDDPAFLKELLESL 300

Query: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQP 360
           WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTE+GRSAVNVLSFLCLDAYQSVQLPQP
Sbjct: 301 WVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTESGRSAVNVLSFLCLDAYQSVQLPQP 360

Query: 361 NLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCV 420
           NLGVRTNALIDTPFL+KTAETIR GTGIPQIFNDEVVVPAFLNRGVSLEDARDY+VVGCV
Sbjct: 361 NLGVRTNALIDTPFLLKTAETIRLGTGIPQIFNDEVVVPAFLNRGVSLEDARDYAVVGCV 420

Query: 421 ELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS 480
           ELSIPGRTYGLHDIAMFNLLKVMEI L+ENEGN  LTYE LL  IRAKISHYITLMVEGS
Sbjct: 421 ELSIPGRTYGLHDIAMFNLLKVMEISLYENEGNDTLTYEALLAHIRAKISHYITLMVEGS 480

Query: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGM 540
           NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHAL G+
Sbjct: 481 NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALNGL 540

Query: 541 VFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKE 600
           VF+QQRLSFD LLS+LK NFATPEGEK+RARLINRFEKYGNDID VDNISAELLR+YCKE
Sbjct: 541 VFDQQRLSFDALLSILKNNFATPEGEKIRARLINRFEKYGNDIDNVDNISAELLRYYCKE 600

Query: 601 VEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTA 660
           VEKYQNPRGG FTPGSYTVSAHVPLG+VVGATPDGRFAGEQLADGGLSPMLGQD QGPTA
Sbjct: 601 VEKYQNPRGGQFTPGSYTVSAHVPLGAVVGATPDGRFAGEQLADGGLSPMLGQDMQGPTA 660

Query: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720
           VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
Sbjct: 661 VLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD 720

Query: 721 TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           TLREAQ RPQD+AGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
Sbjct: 721 TLREAQLRPQDFAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765



>ref|YP_878969.1| pyruvate formate-lyase [Clostridium novyi NT]
 gb|ABK62487.1| pyruvate formate-lyase [Clostridium novyi NT]
          Length = 850

 Score =  627 bits (1617), Expect = e-178
 Identities = 349/841 (41%), Positives = 487/841 (57%), Gaps = 85/841 (10%)

Query: 4   RISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEEL 63
           RI+ L   L++ T EI  +RA+L T S ++TE  P+++RRAKA   IL  + I IRD EL
Sbjct: 16  RINILIEDLYSVTPEIEADRAVLITESFKETESMPMVIRRAKALEKILSEMPIVIRDSEL 75

Query: 64  IAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRS 123
           I GN T KPRA  + PE    WLL E D+   R  D F ISE+ K   RE +F YW+ ++
Sbjct: 76  IVGNLTKKPRAAQIFPEFSNKWLLDEFDRLANRKGDVFLISEDTKDKLRE-VFKYWDGKT 134

Query: 124 MKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQ 182
             +F    M DE K A +  +F++ N    G GHI +DY ++L+ G   ++ ++Q+  ++
Sbjct: 135 TNEFATEIMFDETKEAMDEGVFTVGNYYFNGVGHICVDYAKVLSKGFNGIIQEVQEERKK 194

Query: 183 QPE--------NHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISR 234
             +        + F  +  +  +A+ K   R+ E A+T+A+   D++RREELL IA    
Sbjct: 195 ADKGDPNYIKKDQFLTSVEITCKAAVKFAKRFGEEAKTLASRTMDSKRREELLQIA---- 250

Query: 235 HNAQHKP----QTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-D 289
           HN +  P    + F++A Q FW++  I+Q ESN  S+S  RFDQYM P+++  +  G  D
Sbjct: 251 HNCEWVPANPARNFYEALQAFWFVQAIIQIESNGHSISPMRFDQYMYPYFKNDIESGRID 310

Query: 290 AAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCL 349
            +  +ELL+ LWVK ND+  +R   S + F G+P     ++GG T  G  A N LSF+CL
Sbjct: 311 MSRAQELLDCLWVKFNDVNKVRDEGSTKAFGGYPMFQNLIVGGQTIYGEDATNELSFMCL 370

Query: 350 DAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLE 409
           +A    +LPQP++ +R         L K AE  R G G+P  +NDEV++P+ LNRG+S+E
Sbjct: 371 EATAHTKLPQPSISIRGWNKTPDELLFKAAEVSRLGLGMPAYYNDEVIIPSLLNRGLSME 430

Query: 410 DARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAAL------------T 457
           DARDY ++GCVE    G+T G HD A FN+ KV+EI ++    N               +
Sbjct: 431 DARDYGIIGCVEPQKGGKTEGWHDAAFFNMAKVLEITMNNGMSNGKQLGPKTGDVTLFNS 490

Query: 458 YEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARY 517
           +E  +   R ++ +++ L+    N  D+ H   AP+P LSS + DC+ KG+ + +GGA Y
Sbjct: 491 FEEFMNAYREQMKYFVKLLANADNCVDVAHGMRAPLPFLSSMVYDCIGKGKSLQEGGAHY 550

Query: 518 NFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFA---------------- 561
           NF+G QG+G+AN +DSL  +K +VFE++ +S  +L   L  NF                 
Sbjct: 551 NFTGPQGVGVANTADSLEVIKKLVFEERLVSMGDLKEALDTNFGECNSSNSLNLNSINNI 610

Query: 562 TPEG-------------------------------------EKVRARLINRFEKYGNDID 584
            PE                                      E +R  LINR  KYGNDID
Sbjct: 611 NPENLNRETIMAVIEKLLFKESNISVNNLNSNINLGNYQGKESLRQMLINRAPKYGNDID 670

Query: 585 EVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLAD 644
           EVDN++ E    YCKEVEKY NPR G F PG Y VSA+VP+G+  GATPDGR AGE LAD
Sbjct: 671 EVDNLAREAALIYCKEVEKYTNPRNGKFQPGLYPVSANVPMGAQTGATPDGRKAGEPLAD 730

Query: 645 GGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAF 704
            G+SP+ G+D  GPTA + SV+KLD+ + SNGTL N KF P+ L+GEAGLR L+  +R F
Sbjct: 731 -GVSPVSGRDQNGPTAAVNSVAKLDHAIASNGTLFNQKFHPSALQGEAGLRNLSALVRTF 789

Query: 705 TQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQ 764
            + K  H+QFNVV+ + L +AQ+ P+ Y  LVVRVAGYSA F  L K IQDDII+RT HQ
Sbjct: 790 FENKGMHVQFNVVSREMLLDAQKNPEKYKSLVVRVAGYSAHFTSLDKSIQDDIIKRTEHQ 849

Query: 765 L 765
           L
Sbjct: 850 L 850



>ref|ZP_00910118.1| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052]
 gb|EAP59277.1| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052]
          Length = 795

 Score =  607 bits (1565), Expect = e-172
 Identities = 334/786 (42%), Positives = 488/786 (62%), Gaps = 33/786 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           M+ RI  LK  + +  R  S+E+AL+ T ++++ E +PVI++RA A    L  +EI + D
Sbjct: 17  MSQRIKNLKQKMLSEKRYASIEQALIITETYKENEDKPVIIKRALALKNSLSKLEIGVDD 76

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELI GNRT   R G++ PE    W+ KE +  PTRPQD+F ++  D   +R+ + PYW+
Sbjct: 77  EELIVGNRTKGVRYGVVFPESGSSWIDKEFESLPTRPQDKFNVNLNDIETFRKVIKPYWD 136

Query: 121 KRSMKDFIN---GQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGEL----V 173
             S++D I    G+  DE+      ++  INQ D  QGHI  +    L  G   +    +
Sbjct: 137 GHSLEDVIRQRYGKEIDEI-----AKVVKINQKDHAQGHICPNCREWLALGPEGIKQRAI 191

Query: 174 AQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEIS 233
            +M+   ++  E  FY++ ++++E +Q+ ++RY +L +  A +  + +   ++L +AEI 
Sbjct: 192 EKMKNSTKESKE--FYESVIIVMEGAQEFMMRYHDLMKEKAESICEEELVADMLQVAEIC 249

Query: 234 RHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-DAAF 292
           ++ ++   QTF +A Q  W++ +IL  ESNASS S GR D+++ P+Y+  +  G  D   
Sbjct: 250 KNISRRPAQTFHEAVQAIWFLFVILHMESNASSFSPGRMDEFLYPYYKRDIHLGNIDDKK 309

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
             E++E LW+K N+IV LR++ SA++FAGFP G+   +GG  E      N LSFL L A 
Sbjct: 310 ALEIIECLWLKFNEIVYLRNSHSAKFFAGFPIGFNIAIGGQDEKSNDFSNELSFLFLKAQ 369

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
           + + LPQPNL VR +       L ++ + +  G+G+PQ FNDE VVP+ ++ G+  +DAR
Sbjct: 370 EHLGLPQPNLSVRLHKNTSEKLLKESIKVVAKGSGMPQFFNDESVVPSMIDLGIKEKDAR 429

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLH------------ENEGNAAL--TY 458
           DY++VGCVEL+  G   G  D AMFNL KV+EI L+            ++ GN      Y
Sbjct: 430 DYAIVGCVELTTQGNNLGWSDAAMFNLNKVLEITLNGGKCLISGDSLSQDLGNLTTYEKY 489

Query: 459 EGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYN 518
           E L E    +I ++I  M+      +  H D  P P LSS I DC+EKG D+T GGA YN
Sbjct: 490 EDLEEAFAKQIDYFIDRMILACEQVEKAHIDVLPSPFLSSVIDDCIEKGVDVTAGGAVYN 549

Query: 519 FSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEG-EKVRARLINRFE 577
            SG+Q I +ANL+DSL A+K +V++++R+S +ELL  L+ NF   EG E +RA L+NR  
Sbjct: 550 LSGIQMIQVANLADSLAAIKLLVYDEKRISKEELLKALQNNF---EGYEVIRAMLLNRAP 606

Query: 578 KYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRF 637
           KYGNDI  VD I A+  R++  +++ Y N RGG +  G YTVSAHVP+G  VGA+ DGR+
Sbjct: 607 KYGNDIQWVDEIGAKWARYFNGKLKSYTNYRGGKYHTGMYTVSAHVPMGENVGASADGRY 666

Query: 638 AGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKL 697
           A   LADGG+SP+ G+D  GPTAVLKSVSKLDN L +NG LLN+KF P   + E G  K 
Sbjct: 667 AKAPLADGGMSPVYGRDIAGPTAVLKSVSKLDNVLTTNGGLLNMKFLPEFFKHEIGRDKF 726

Query: 698 ADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDI 757
           A FLR F  L++ HIQFNV+  + L  AQ+ P++Y  L VRVAGY+A+F EL+ E+Q++I
Sbjct: 727 ARFLRTFVDLEIPHIQFNVLRKEDLLAAQKDPENYRSLTVRVAGYTAYFTELAGELQNEI 786

Query: 758 IRRTAH 763
           I RT++
Sbjct: 787 IARTSY 792



>pdb|1R8W|A Chain A, Native Structure Of The B12-Independent Glycerol
           Dehydratase From Clostridium Butyricum
 pdb|1R8W|B Chain B, Native Structure Of The B12-Independent Glycerol
           Dehydratase From Clostridium Butyricum
 pdb|1R9D|A Chain A, Glycerol Bound Form Of The B12-Independent Glycerol
           Dehydratase From Clostridium Butyricum
 pdb|1R9D|B Chain B, Glycerol Bound Form Of The B12-Independent Glycerol
           Dehydratase From Clostridium Butyricum
 pdb|1R9E|A Chain A, Structure Of The B12-Independent Glycerol Dehydratase With
           1,2-Propanediol Bound
 pdb|1R9E|B Chain B, Structure Of The B12-Independent Glycerol Dehydratase With
           1,2-Propanediol Bound
 gb|AAM54728.1| glycerol dehydratase [Clostridium butyricum]
          Length = 787

 Score =  604 bits (1558), Expect = e-171
 Identities = 319/783 (40%), Positives = 482/783 (61%), Gaps = 28/783 (3%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T RI+ LK  +      +  ERA+L T S +QTEG+P ILRRA A  +ILE++ I+IRD+
Sbjct: 10  TERINILKAQILNAKPCVESERAILITESFKQTEGQPAILRRALALKHILENIPITIRDQ 69

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+ T +PR+  + PE    WL  ELD+   R  D F ISEE K   ++ +F YW  
Sbjct: 70  ELIVGSLTKEPRSSQVFPEFSNKWLQDELDRLNKRTGDAFQISEESKEKLKD-VFEYWNG 128

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           ++  +     MT+E + A N  +F++ N    G GH+ +DY ++L  G   ++ + ++  
Sbjct: 129 KTTSELATSYMTEETREAVNCDVFTVGNYYYNGVGHVSVDYGKVLRVGFNGIINEAKEQL 188

Query: 181 QQQ--------PENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
           ++          +  F  + ++  EA+  ++ RYA+ A+ +A N +DA+R+ EL  IA+I
Sbjct: 189 EKNRSIDPDFIKKEKFLNSVIISCEAAITYVNRYAKKAKEIADNTSDAKRKAELNEIAKI 248

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
               +    ++F++ACQLFW+++ I+  ESN  S+S  RFDQYM P+Y+      +   F
Sbjct: 249 CSKVSGEGAKSFYEACQLFWFIHAIINIESNGHSISPARFDQYMYPYYENDKNITDK--F 306

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +EL++ +W+K NDI  +R   S ++F G+P     ++GG    G+ A N +S++ L+A 
Sbjct: 307 AQELIDCIWIKLNDINKVRDEISTKHFGGYPMYQNLIVGGQNSEGKDATNKVSYMALEAA 366

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V+LPQP+L VR        FL++ AE  R G G+P  +NDEV++PA ++RG++LEDAR
Sbjct: 367 VHVKLPQPSLSVRIWNKTPDEFLLRAAELTREGLGLPAYYNDEVIIPALVSRGLTLEDAR 426

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN-EGNAAL-----------TYEG 460
           DY ++GCVE   PG+T G HD A FNL +++E+ ++   + N  +           +++ 
Sbjct: 427 DYGIIGCVEPQKPGKTEGWHDSAFFNLARIVELTINSGFDKNKQIGPKTQNFEEMKSFDE 486

Query: 461 LLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFS 520
            ++  +A++ +++  M    N  DI H + AP+P LSS + +C+ KG+ + DGGA YNFS
Sbjct: 487 FMKAYKAQMEYFVKHMCCADNCIDIAHAERAPLPFLSSMVDNCIGKGKSLQDGGAEYNFS 546

Query: 521 GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYG 580
           G QG+G+AN+ DSL A+K +VF++ +++  EL   L  +F     E+++A L+    K+G
Sbjct: 547 GPQGVGVANIGDSLVAVKKIVFDENKITPSELKKTLNNDF--KNSEEIQA-LLKNAPKFG 603

Query: 581 NDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGE 640
           NDIDEVDN++ E    YC+EV KY NPRGG F PG Y  S +V  GS+ GATPDGR +G+
Sbjct: 604 NDIDEVDNLAREGALVYCREVNKYTNPRGGNFQPGLYPSSINVYFGSLTGATPDGRKSGQ 663

Query: 641 QLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADF 700
            LAD G+SP  G D  GPTA   SVSKLD+ + SNGTL N KF P+ L+G+ GL  L+  
Sbjct: 664 PLAD-GVSPSRGCDVSGPTAACNSVSKLDHFIASNGTLFNQKFHPSALKGDNGLMNLSSL 722

Query: 701 LRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRR 760
           +R++   K  H+QFNV++   L  AQ+ P+ Y  L+VRVAGYSA F+ L K IQ+DII R
Sbjct: 723 IRSYFDQKGFHVQFNVIDKKILLAAQKNPEKYQDLIVRVAGYSAQFISLDKSIQNDIIAR 782

Query: 761 TAH 763
           T H
Sbjct: 783 TEH 785



>ref|YP_878877.1| pyruvate formate-lyase [Clostridium novyi NT]
 gb|ABK62429.1| pyruvate formate-lyase [Clostridium novyi NT]
          Length = 803

 Score =  602 bits (1552), Expect = e-170
 Identities = 323/798 (40%), Positives = 487/798 (61%), Gaps = 40/798 (5%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T R+ +LK  + + T  I +ERA L T S ++TE +P+I+R+AKA   IL  + I IR+ 
Sbjct: 12  TKRVEKLKEQILSATPCIEVERARLLTESFKETENQPIIIRKAKALEKILNEMPIVIREG 71

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+ T   R+  + PE    WL++E ++ P R  D F ISEE K    + +F YWE 
Sbjct: 72  ELIVGSLTKNSRSAQVFPEFSNKWLVEEFEKLPKRTSDSFQISEEVKSELID-IFKYWEG 130

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHG----LGELVAQM 176
           +++ +     M  E   A   ++F++ N    G GHI +DY ++L  G    + E+ A+M
Sbjct: 131 KTVSELATSYMPKETLEAMGAKVFTVANYYFNGLGHISVDYKKVLELGFKGIIEEIKAKM 190

Query: 177 QQHCQQQPE----NHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
               +  PE      F++A ++  EA+  +  RYA+LA+ ++ N  D +R+EELL IAEI
Sbjct: 191 DSADKSDPEYIKKRTFWEAVIISCEAAIDYARRYAKLAKELSENTEDCKRKEELLKIAEI 250

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSL-----TQG 287
                ++   TF++ACQ FW++  I+  ESN  ++S  RFDQYM P++++ +     T+ 
Sbjct: 251 CSKVPENPATTFYEACQSFWFVQAIISLESNGHAISPARFDQYMYPYFKSDVDNNVVTKE 310

Query: 288 EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFL 347
           E+    +E+L+ LWVK ND+  +R  ++ + F+G+      ++GG TE G+ A N LS++
Sbjct: 311 EN----REILQCLWVKFNDLTKVRDETTTKAFSGYSMFQNLIVGGQTEEGKDATNELSYM 366

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
           CLDA  S++LPQP+L VR  +     FL++T E  R GTG+P  +NDEV++P  +N G++
Sbjct: 367 CLDATGSLKLPQPSLSVRIWSKTPEEFLIRTCELTRLGTGLPAFYNDEVIIPMLVNNGMT 426

Query: 408 LEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE------------NEGNAA 455
           LEDARDY++VGCVE   PG+T G +D A FNL +++++ +               E    
Sbjct: 427 LEDARDYAIVGCVEPQKPGKTDGWYDAAFFNLAQILKLTIDNGKMDGKQVGPKTGEFEEF 486

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
              + ++E  + ++ +++  MV   N  DI HR+ AP+P LS+ + DC+ KG+ I +GG 
Sbjct: 487 KDIDEVIEAYKKQMEYFVAQMVSADNCVDIAHRERAPLPFLSAMLDDCIAKGKSIQEGGG 546

Query: 516 RYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK-------- 567
            Y FSG  G+GIAN+ DS  A+K +VF+ ++++ D+L   L  NF   E ++        
Sbjct: 547 HYRFSGPLGVGIANVGDSFMAIKKLVFDDEKITLDKLKQALDGNFGKDEKDEGKKNELQG 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGS 627
           ++  L++R  K+GNDIDEVD  + E    YC EV K+ N RGG F PG Y VS +V LGS
Sbjct: 607 IKQMLLHRAPKFGNDIDEVDEFTREGALIYCNEVLKHFNQRGGKFLPGLYPVSNNVHLGS 666

Query: 628 VVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPAT 687
           +VGATPDGR A + +AD G+SP  G D  GPTA   SV+KL++    +GTL N KF P++
Sbjct: 667 LVGATPDGREAYQPIAD-GVSPTRGADVNGPTAAANSVAKLEHYAAPSGTLFNQKFNPSS 725

Query: 688 LEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
           L+G+ GLR L   +R++   K  HIQFNVV+ + L +AQ+ P+ Y  L+VRVAGYSA F+
Sbjct: 726 LKGDNGLRNLGTLIRSYFDHKGMHIQFNVVDKNVLLDAQKHPEKYRDLIVRVAGYSAQFI 785

Query: 748 ELSKEIQDDIIRRTAHQL 765
            L+KEIQDDII+RT  +L
Sbjct: 786 CLNKEIQDDIIKRTEQEL 803



>ref|YP_877303.1| pyruvate formate-lyase [Clostridium novyi NT]
 gb|ABK60580.1| pyruvate formate-lyase [Clostridium novyi NT]
          Length = 790

 Score =  596 bits (1536), Expect = e-168
 Identities = 318/784 (40%), Positives = 474/784 (60%), Gaps = 26/784 (3%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T R+ +L+  +      +  ERALL T S+++TE +P+ILRRA A   IL ++ I IR+ 
Sbjct: 9   TERVKKLRAQILDVVPCVETERALLITESYKETEEKPMILRRALALKKILNNLPIVIREG 68

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+ T +PR+  + PE    WL  ELD+   R  D F I+EEDK+  +E +F YW+ 
Sbjct: 69  ELIVGSLTKRPRSSQVFPEFSNKWLQDELDRLDKRKGDVFEIAEEDKKKLKE-VFEYWDG 127

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           ++  +     M+ E   A N+ IF++ N    G GHI ++Y ++L  G   ++ + ++  
Sbjct: 128 KTTHELATSYMSKETIDAMNSDIFTVGNYYFNGVGHISVNYGKVLAVGFNGIIEEAKKSL 187

Query: 181 QQQPEN--------HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
           +   +          F  + ++  EA+  +  RY++ A+ +A   +D  R+ EL  IA I
Sbjct: 188 ESSDKTSPSYIKKEQFLNSVIISCEAAIDYAKRYSDEAKKLADKTSDPIRKSELNEIARI 247

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA- 291
                +    +F++ACQ FW+++ I+  ESN  S+S  RFDQYM P+Y+  + +G+    
Sbjct: 248 CSKVPKEGASSFYEACQAFWFVHAIINVESNGHSISPTRFDQYMYPYYKKDMDEGKITQD 307

Query: 292 FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDA 351
           F +EL++ +W+K NDI  +R   S +YF G+P     ++GG    G+   N LS++ L+A
Sbjct: 308 FAQELVDCIWIKLNDINKVRDEISTKYFGGYPMYQNLIVGGQNFEGKDVTNELSYMALEA 367

Query: 352 YQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDA 411
              V+LPQP+L VR        FL++  E  R G G+P  +NDEV++PA + RGV+LEDA
Sbjct: 368 SAHVRLPQPSLSVRIWNKTPDEFLLRACELTREGLGLPAYYNDEVIIPALVARGVTLEDA 427

Query: 412 RDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE------------NEGNAALTYE 459
           R Y V+GCVE   PG+T G HD A FNL +++E+ +H              E     +++
Sbjct: 428 RSYGVIGCVEPQCPGKTEGWHDSAFFNLARIVELAIHSGKDKGVQIGPKTKEFTEMKSFD 487

Query: 460 GLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNF 519
             +E  +A++ +++  M    N  DI H + AP+P LSS + +C+  G+ + +GGA YNF
Sbjct: 488 EFMEAYKAQMEYFVKHMCVADNCIDIAHAERAPLPFLSSMVENCISVGKSLQEGGAHYNF 547

Query: 520 SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKY 579
           SG QG+G+AN+ DSL A+K +VFE ++++ ++L   L +NF   +  +V+  L  +  KY
Sbjct: 548 SGPQGVGVANVGDSLMAIKKLVFEDEKITKEQLKEALDSNF--EKYPEVKQILSKQAPKY 605

Query: 580 GNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAG 639
           GNDIDEVD ++      Y KEV KY NPRGG F PG Y  S +V  GS+ GATPDGR A 
Sbjct: 606 GNDIDEVDELARVGALVYSKEVNKYTNPRGGQFQPGLYPSSINVYFGSLTGATPDGRSAE 665

Query: 640 EQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLAD 699
           E LAD G+SP  G+D  GPTA   SV+KLD+ + SNGTL N KF PA L+G+ GL+ LA 
Sbjct: 666 EPLAD-GVSPSRGKDVSGPTAAGNSVAKLDHFIASNGTLFNQKFHPAALKGDKGLQNLAA 724

Query: 700 FLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIR 759
            +R++   K  H+Q+NV++ DTL +AQQ+P+DY  L+VRVAGYSA F+ L K IQDDII+
Sbjct: 725 VVRSYFDQKGMHVQYNVIDRDTLIKAQQKPEDYRDLIVRVAGYSAQFISLDKTIQDDIIK 784

Query: 760 RTAH 763
           RT H
Sbjct: 785 RTEH 788



>ref|NP_781591.1| formate acetyltransferase 2 [Clostridium tetani E88]
 gb|AAO35528.1| formate acetyltransferase 2 [Clostridium tetani E88]
          Length = 803

 Score =  593 bits (1529), Expect = e-167
 Identities = 311/790 (39%), Positives = 479/790 (60%), Gaps = 32/790 (4%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T+R+ RLK  +F+    +  +RA+L T S ++TE +P+I+R+AKA   IL  + I IRD 
Sbjct: 12  TDRVKRLKEQIFSAVPCVEADRAILLTESFKETEDQPIIIRKAKALEKILNEIPIVIRDG 71

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+ T  PR+  + PE    WL++E D+   R  D F IS+E K     E+F YWE 
Sbjct: 72  ELIVGSLTKNPRSAQVFPEFSNKWLVEEFDKLNKRTSDAFEISDEAKS-QLIEVFKYWEG 130

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           +++ +     MTD+   A N ++F++ N    G GHI +DY ++L  G   ++ ++ +  
Sbjct: 131 KTVSELATSYMTDDTIDAMNAKVFTVANYHFNGLGHISVDYEKVLKKGFSGIIKEVNETI 190

Query: 181 QQQPENH--------FYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
               +N+        F+ A ++  EA+  +  RY++LA+ +A   T+A R++ELL I++I
Sbjct: 191 NNADKNNPEYIKQRRFWDAIIISCEAAISYAKRYSQLAKELAQKETNATRKDELLNISKI 250

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLT-QGEDAA 291
                +    TF +ACQ FW++  I+  ESN  ++S  RFDQYM P+++  +    ++  
Sbjct: 251 CEKVPEKPATTFQEACQSFWFVQAIISLESNGHAISPARFDQYMYPYFKHDIDLHPKNRE 310

Query: 292 FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDA 351
             +E+L  LWVK ND+  +R  ++ + F+G+      ++GG T  G+ A N LS++C+DA
Sbjct: 311 SAREILHCLWVKFNDLTKVRDETTTKAFSGYSMFQNLIVGGQTPEGKDATNELSYMCMDA 370

Query: 352 YQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDA 411
             ++ LPQP+L VR  +     FL+++ E  R GTG+P  +NDEV++P  +N G++LEDA
Sbjct: 371 TGTLMLPQPSLSVRIWSKAPEEFLIRSCELTRLGTGLPAFYNDEVIIPMLVNHGLTLEDA 430

Query: 412 RDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE------------NEGNAALTYE 459
           RDY++VGCVE   PG+T G +D A FN+ KV+E+ ++              E  +    +
Sbjct: 431 RDYAIVGCVEPQKPGKTDGWYDAAFFNMAKVLEMTINNGKVDGKQIGPKTGEFTSFSNID 490

Query: 460 GLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNF 519
             +E  + +  ++++ MV   N  DI H + AP+P LS  + DC+ KG+ I +GG  Y F
Sbjct: 491 EFIEAYKKQTEYFVSYMVSADNCVDIAHAERAPLPFLSCMLDDCISKGKSIQEGGGHYRF 550

Query: 520 SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFA----TPEG----EKVRAR 571
           SG  G+GIAN+ DS  A+K +VF++++L+ +E+   +  N+      PE     + ++  
Sbjct: 551 SGPLGVGIANIGDSFMAIKKLVFDEKKLTLNEIKEAIDTNYGEFEENPEKKIKYKDIQQM 610

Query: 572 LINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGA 631
           L+NR  K+GNDIDEVD  +      YCKEVEK+ N RGG F PG Y VS +V LG++V A
Sbjct: 611 LLNRAPKFGNDIDEVDEYTRLGALIYCKEVEKHTNQRGGQFIPGLYPVSNNVHLGTLVSA 670

Query: 632 TPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGE 691
           TPDGR A + LAD G+SP  G D  GPTA   SV+KL++    +GTL N KF+P++L+G+
Sbjct: 671 TPDGRGAKKPLAD-GVSPTRGVDVNGPTAAANSVAKLEHFCAPSGTLFNQKFSPSSLQGD 729

Query: 692 AGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSK 751
            GL+ LA  +R++   K  H+QFNVV+ + L +AQ+RP+ Y  L+VRVAGYSA F+ L  
Sbjct: 730 NGLKNLASLIRSYFDQKGMHMQFNVVDKNVLIDAQKRPEQYRDLIVRVAGYSAQFICLDN 789

Query: 752 EIQDDIIRRT 761
            IQDDII+RT
Sbjct: 790 AIQDDIIKRT 799



>ref|YP_356813.1| glycerol dehydratase [Pelobacter carbinolicus DSM 2380]
 gb|ABA88643.1| glycerol dehydratase [Pelobacter carbinolicus DSM 2380]
          Length = 799

 Score =  590 bits (1520), Expect = e-166
 Identities = 317/783 (40%), Positives = 461/783 (58%), Gaps = 27/783 (3%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T R+ ++K    A T EI  ERA L T S+++TEG+P+ +RRAKA   IL  + + I D+
Sbjct: 17  TERVEKIKARFLATTPEICAERAKLITESYKETEGQPMSIRRAKALEKILLEMSVYIDDD 76

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI GN+   PR+  + PE    W+  ELD+   R  D F ISE+ K+  RE++FPYW+ 
Sbjct: 77  ELIVGNQCSMPRSAPIYPEFSCEWVEDELDRLAKRSADVFLISEDVKKTLREDVFPYWKG 136

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQ-- 178
           ++  +     M  E   A N  ++++ N    G GHI  +Y +++N GL  ++A+ +   
Sbjct: 137 KTNHEIATALMKQEAIDAGNAVVYTVGNYYFNGVGHISANYGKVMNQGLNSVIAKAEAAK 196

Query: 179 ------HCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
                    Q    HF ++ ++  +A      R+A+ AE++AA   +A R+ ELL IA I
Sbjct: 197 EKFDFADAHQMKSLHFLESTIIANKAVIAFANRFADEAESLAAAEKNAARKAELLEIARI 256

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
            R       +TF +A Q FW++++++Q ESN  S+S  RFDQY  PFY  S     D   
Sbjct: 257 CRKVPAEPAETFQEAVQAFWFIHLVIQIESNGHSISPMRFDQYCYPFYAASKNSLSDEK- 315

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +E+L+ LW+K N +  +R  +S   FAG+P     ++GG+   G+ A N LS + L   
Sbjct: 316 AQEMLDLLWLKFNGLNKVRDENSTMAFAGYPMFMNIIVGGVDREGKDATNELSLMLLQCA 375

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
            + +L  P+L +R +        MK AE  R G G+P  FND  ++PA L+RG++LEDAR
Sbjct: 376 ANTKLYAPSLSIRVHEGTPDVLYMKAAEVSRMGLGVPAYFNDRTIIPALLSRGLTLEDAR 435

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE--------------NEGNAALTY 458
           DY ++GCVE  + G+T G HD A FN+ KV+E+ L+                +     ++
Sbjct: 436 DYGIIGCVEPQVGGKTEGWHDAAFFNMAKVVELTLNNGYDKRTEMQVGPKTGDVTEMKSF 495

Query: 459 EGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYN 518
           + ++     ++ +++ LM    N+ D+ H    P+P LSS + DC+ +G+ + +GGA YN
Sbjct: 496 DDVMAAYAKQMEYFVGLMCHADNMVDLAHGQNVPLPFLSSLVEDCIGRGKSLQEGGAIYN 555

Query: 519 FSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEK 578
           FSG QG+G+AN  DSL A+K + F+ + +S  EL  VL  +FA    E++R  +INR  K
Sbjct: 556 FSGPQGVGVANAGDSLTAIKKLCFDDKVISLPELKEVLDKDFA--GAEEIRQMVINRAPK 613

Query: 579 YGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFA 638
           YGND D  D I+ E    YC EV KY+NPRGG F PG Y  SA+VP G VV ATPDGR  
Sbjct: 614 YGNDDDYADEIAVESANIYCAEVNKYRNPRGGQFQPGLYPASANVPFGGVVEATPDGRKK 673

Query: 639 GEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLA 698
           G  LAD G+SP+ G D  GPTA + SV+KLD+ + SNGTLLN KF P  ++GE GLR L 
Sbjct: 674 GTPLAD-GVSPIGGADISGPTATVNSVAKLDHEVTSNGTLLNQKFHPNAVKGEEGLRNLI 732

Query: 699 DFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDII 758
                + +    H+Q+NV++ +TL +AQ++P+D+ GLVVRVAGYSAFF  L K +QDDII
Sbjct: 733 AVTETYFKNGGFHVQYNVIDRNTLLDAQKKPEDFKGLVVRVAGYSAFFTALDKSLQDDII 792

Query: 759 RRT 761
            RT
Sbjct: 793 SRT 795



>ref|ZP_00813776.1| Pyruvate formate-lyase [Shewanella putrefaciens CN-32]
 ref|YP_961832.1| pyruvate formate-lyase [Shewanella sp. W3-18-1]
 gb|EAO94943.1| Pyruvate formate-lyase [Shewanella putrefaciens CN-32]
 gb|ABM23278.1| pyruvate formate-lyase [Shewanella sp. W3-18-1]
          Length = 847

 Score =  573 bits (1478), Expect = e-161
 Identities = 335/839 (39%), Positives = 469/839 (55%), Gaps = 82/839 (9%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T+RI  L+  +   T  I  +RA L T S+++TE  P+I+RRAKA   IL  + ++IR  
Sbjct: 12  TDRIRALREQILDTTPCIETDRARLITESYKETESLPMIIRRAKALEKILAELPVTIRAG 71

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+ TV P +  + PE    WL  E D+   R  DRF I++E K+   + +F YWE 
Sbjct: 72  ELIVGSLTVTPHSTQIYPEYSNRWLQDEFDRLNLRKGDRFTITDEAKQ-QLDSVFGYWEG 130

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHG----LGELVAQM 176
           ++  +     M  E        +F++ N    G GHI +DY R+L  G    + ++VA M
Sbjct: 131 KTTNELATSYMLPETLDCMAENVFTVGNYYFNGVGHIAVDYARVLARGYKGIIQDVVAAM 190

Query: 177 QQHCQQQP----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
               ++ P    +  FY+A ++   A+     RYA  A T+A   +   R++ELL IAEI
Sbjct: 191 ASADKKDPAFLKKESFYKAVIISCNAAINFAHRYAVKARTLAEQASPV-RKKELLKIAEI 249

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
                ++    F++ACQ FW+ + I+Q ESN  S+S  RFDQYM P+ +   +  E+ A 
Sbjct: 250 CDKVPENGASNFYEACQSFWFAHAIIQLESNGHSISPARFDQYMYPYLEKDSSLSEEQA- 308

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +ELL+ LW+K ND+  +R   S + F G+P     ++GG T  G+ A N LSF+ + A 
Sbjct: 309 -QELLDCLWLKFNDVNKVRDEGSTKGFGGYPMFQNLIVGGQTSGGQDATNRLSFMAMTAT 367

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V+L +P+L VR  +      L+K  E  R G GIP  +NDEVV+PA +NRG++LEDAR
Sbjct: 368 AHVRLHEPSLSVRVWSKSPDDLLLKACEVSRLGMGIPAYYNDEVVIPALINRGLTLEDAR 427

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN------------EGNAALTYEG 460
           +Y ++GCVE   PG+T G HD A +N+ KV+EI L+              E ++  + E 
Sbjct: 428 EYGIIGCVEPQRPGKTEGWHDAAFYNMSKVLEITLNNGRCGDKQLGPKTGELDSFQSIED 487

Query: 461 LLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFS 520
           ++E  R +  +++  +    N  D+ H + AP+P LS  + DC+ +G+ + +GGA YNF+
Sbjct: 488 IIEAYRKQNEYFVYHLAMADNSVDLAHMERAPLPFLSCMVDDCISRGKSVQEGGAHYNFT 547

Query: 521 GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANF---------------ATPE- 564
           G QG+G+AN+ DSL A+K +VFE+ +LS   L   L ANF               +TP+ 
Sbjct: 548 GPQGVGVANVGDSLMAIKRLVFEEGQLSLGHLKEALDANFGVSGGIEKPDTIATESTPKQ 607

Query: 565 ---------------GEK-------------------------VRARLINRFEKYGNDID 584
                          GE                          VR  LIN   K+GNDID
Sbjct: 608 DATYELVLEAVKKVLGESGALALTSLNSNPPEPVKGANAGLTAVRQLLINGAPKFGNDID 667

Query: 585 EVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLAD 644
           EVD ++      YC+EVEKY NPRGG F  G Y VSA+V LG  VGATPDGR AG+ L D
Sbjct: 668 EVDMLARTGAEIYCREVEKYTNPRGGLFQAGLYPVSANVALGESVGATPDGRLAGQPLPD 727

Query: 645 GGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAF 704
           G +SP  G D +GPTA   SV+KLD+ L SNGTL N KF PA L+G+ GL  LA  LR +
Sbjct: 728 G-VSPSRGMDTKGPTAAANSVAKLDHFLASNGTLFNQKFHPAALKGDEGLYHLAALLRGY 786

Query: 705 TQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAH 763
              K  H+QFNV++ +TL  AQ+ P+ Y  LVVRVAGYSA FV L K +QDDII RT H
Sbjct: 787 FDQKGMHVQFNVIDRNTLLAAQKEPEKYRDLVVRVAGYSAQFVSLDKSVQDDIILRTEH 845



>gb|ABC25539.1| glycerol dehydratase [Roseburia inulinivorans]
          Length = 843

 Score =  560 bits (1444), Expect = e-158
 Identities = 320/829 (38%), Positives = 464/829 (55%), Gaps = 72/829 (8%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           ++RI RL   L+A   EI   RA L T S + TEG+PV++R+A+A  +IL+++ I IR E
Sbjct: 12  SDRIKRLVDHLYAKMPEIEAARAELITESFKATEGQPVVMRKARAFEHILKNLPIIIRPE 71

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDK-RIYREELFPYWE 120
           ELI G+ T+ PR     PE    WL  E +   TR  D F ISEE K R+   +   YW+
Sbjct: 72  ELIVGSTTIAPRGCQTYPEFSYEWLEAEFETVETRSADPFYISEETKKRLLAADA--YWK 129

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLG---ELVAQM 176
            ++  +     M  E   A     F+  N    G GH+ + Y  +L  GL    E V + 
Sbjct: 130 GKTTSELATSYMAPETLRAMKHNFFTPGNYFYNGVGHVTVQYETVLAIGLNGVKEKVRKE 189

Query: 177 QQHCQQQPENH-----FYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
            ++C     ++     F ++ L+  +A   +  RYA++AE MA   TDA RR+ELLTIA 
Sbjct: 190 MENCHFGDADYSTKMCFLESILISCDAVITYANRYAKMAEEMAEKETDAARRQELLTIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-DA 290
           + ++  +   ++F +ACQ FW++  +LQ ES+  S+S GRFDQYM P+Y+  L +G    
Sbjct: 250 VCKNVPEFPAESFQEACQSFWFIQQVLQIESSGHSISPGRFDQYMYPYYEKDLKEGSLTR 309

Query: 291 AFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
            + +EL++ +WVK ND+   R  +SA  FAG+      ++GG T  GR A N LSF+C+ 
Sbjct: 310 EYAQELIDCIWVKLNDLNKCRDAASAEGFAGYSLFQNLIVGGQTVQGRDATNDLSFMCIT 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           A + V LP P+L +R         LM+ AE  R G G+P  +NDEV++PA ++RG ++++
Sbjct: 370 ASEHVFLPMPSLSIRVWHGSSKALLMRAAELTRTGIGLPAYYNDEVIIPALVHRGATMDE 429

Query: 411 ARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAAL------------TY 458
           AR+Y+++GCVE  +PG+T G HD A FN+ + +E+       N  +            ++
Sbjct: 430 ARNYNIIGCVEPQVPGKTDGWHDAAFFNMCRPLEMVFSNGYDNGEIASIQTGNVESFQSF 489

Query: 459 EGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYN 518
           +  +E  R ++ + I LMV   N  D  H   AP+P  S  + DC+++G    +GGA YN
Sbjct: 490 DEFMEAYRKQMLYNIELMVNADNAIDYAHAKLAPLPFESCLVDDCIKRGMSAQEGGAIYN 549

Query: 519 FSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANF-----ATPEG-------- 565
           F+G QG GIAN++DSL+ +K +VFE++R++  EL   L+ N+     AT  G        
Sbjct: 550 FTGPQGFGIANVADSLYTIKKLVFEEKRITMGELKKALEMNYGKGLDATTAGDIAMQVAK 609

Query: 566 ---------------------------EKVRAR------LINRFEKYGNDIDEVDNISAE 592
                                      E VR R      +I    KYGNDIDEVD ++ E
Sbjct: 610 GLKDAGQEVGPDVIANTIRQVLEMELPEDVRKRYEEIHEMILELPKYGNDIDEVDELARE 669

Query: 593 LLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLG 652
               Y + +E ++NPRGG +  G Y VSA+VPLG+  GATPDGR A   +AD G+ P  G
Sbjct: 670 AAYFYTRPLETFKNPRGGMYQAGLYPVSANVPLGAQTGATPDGRLAHTPVAD-GVGPTSG 728

Query: 653 QDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHI 712
            D  GPTA   SV+KLD+ + SNGTL N+K  P  + GE GL      +R +   +  H+
Sbjct: 729 FDISGPTASCNSVAKLDHAIASNGTLFNMKMHPTAMAGEKGLESFISLIRGYFDQQGMHM 788

Query: 713 QFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRT 761
           QFNVV+  TL +AQ  P+ Y+GL+VRVAGYSA F  LSK +QDDII+RT
Sbjct: 789 QFNVVDRATLLDAQAHPEKYSGLIVRVAGYSALFTTLSKSLQDDIIKRT 837



>ref|YP_425991.1| Pyruvate formate-lyase [Rhodospirillum rubrum ATCC 11170]
 gb|ABC21704.1| Pyruvate formate-lyase [Rhodospirillum rubrum ATCC 11170]
          Length = 846

 Score =  545 bits (1404), Expect = e-153
 Identities = 313/841 (37%), Positives = 460/841 (54%), Gaps = 81/841 (9%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T+R+ RLK  +      +  ERA+L T ++++TEG P ILRRAKA   I  ++ ++IR++
Sbjct: 10  TDRVMRLKNEILNAKPYVESERAVLVTEAYKETEGLPAILRRAKAAEKIFNNLPVTIRND 69

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G  T  PR+  + PE    W+ KE D   TR  D F I +E  +   +  F YW  
Sbjct: 70  ELIVGAITKNPRSTEICPEFSYDWVEKEFDTMATRLADPFLIPKETAKELHDA-FLYWPG 128

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHG----LGELVAQM 176
           ++  D  +  M+ E K    + +F++ N    G GH+ +DY ++L  G    + E+V  M
Sbjct: 129 KTTSDLASSYMSQEAKDCIASGVFTVGNYFYGGVGHVCVDYGKVLKIGFRGIITEVVQAM 188

Query: 177 QQHCQQQPE----NHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
           ++  +  P+      FY A ++   A+     RYA  A  +A N  +  R+ ELL IA+ 
Sbjct: 189 EKMDRMDPDYIKKQQFYNAVIIAYTAAINFAHRYAAKALELAQNEANPTRKAELLQIAQN 248

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
                ++   TF++ACQ FW++  +LQ ES+  S+S GRFDQYM PF      +  D  F
Sbjct: 249 CARVPENGATTFYEACQSFWFVQCLLQIESSGHSISPGRFDQYMYPFLCAD--KSIDKGF 306

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +EL++ +W+K ND+   R   SA+ FAG+       +GG TE G  A N +S++C++A 
Sbjct: 307 AQELVDCIWIKLNDVNKTRDEVSAQAFAGYAVFQNLCVGGQTEGGLDATNEISYMCMEAT 366

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V+LP P+  +R        FL +  E +R G G+P ++NDEV+VPA  NRGV+L DAR
Sbjct: 367 AHVRLPAPSFSIRVWQGTPDDFLHRACEVVRLGLGVPAMYNDEVIVPALQNRGVTLHDAR 426

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN------------EGNAALTYEG 460
           +Y +VGCVE     +T G HD A FN+ KV+EI L+              E  +    + 
Sbjct: 427 NYGIVGCVEPQCIHKTEGWHDAAFFNVAKVLEITLNNGKAGGKQLGPVTGEFTSFRNMDD 486

Query: 461 LLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFS 520
           L    + ++++++  +VE  N  D+ H +  P+P +S+ + DC+ +G+ + +GGA YNF+
Sbjct: 487 LYAAFQKQMAYFVHYLVEADNCVDLAHGERCPLPFVSALVDDCIGRGKSLQEGGAIYNFT 546

Query: 521 GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATP----------------- 563
           G Q  G+A+  DS++A++  VFE ++++  E+   L ANF  P                 
Sbjct: 547 GPQAFGVADTGDSVYAIQKNVFEDKKITLAEMKEALDANFGLPVGGSAPSAGGDFTEEQV 606

Query: 564 -------------------EGEKVRA--------------------RLINRFEKYGNDID 584
                              +GE  R                     RL++    +GNDID
Sbjct: 607 FAAVRKVLSSNGSMDVSALKGEVYRTLSGQAAPAAGGSSTKYDAIRRLLDASPAFGNDID 666

Query: 585 EVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLAD 644
           +VD ++ E    YC+EVEKY NPRGG F  G Y VSA+V  G  V A PDGR A   LAD
Sbjct: 667 DVDMVARECALIYCREVEKYTNPRGGQFQAGIYPVSANVLFGKDVAALPDGRLAKAPLAD 726

Query: 645 GGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAF 704
           G +SP  GQD +GPTA   SV+KLD+ + SNGTL N KF P+ L G+AGL+  A  +R++
Sbjct: 727 G-VSPRPGQDVKGPTAAANSVAKLDHFIASNGTLYNQKFLPSALAGDAGLQNFASLVRSY 785

Query: 705 TQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQ 764
              K  H+QFNV++  TL +AQ  P+ +  LVVRVAGYSA FV L+KE+QDDII RT   
Sbjct: 786 FDHKGMHVQFNVIDRQTLLDAQLEPEKHNDLVVRVAGYSAQFVVLAKEVQDDIISRTEQT 845

Query: 765 L 765
           L
Sbjct: 846 L 846



>ref|ZP_00907194.1| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052]
 gb|EAP62168.1| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052]
          Length = 844

 Score =  543 bits (1400), Expect = e-152
 Identities = 309/839 (36%), Positives = 458/839 (54%), Gaps = 79/839 (9%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T R+ RLK  +      +  ERA+L T S+++TEG   ILRRAKA   I  ++ I+IR++
Sbjct: 10  TERVERLKRMIVDAIPYVESERAVLVTESYKETEGLSPILRRAKAVEKIFNNLPITIRED 69

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           EL+ G  T  PR+  + PE    W+ KE D    R  D F I +E       E F YW+ 
Sbjct: 70  ELVVGAITKNPRSTEICPEFSYDWVAKEFDTMGARVADPFQIPKETAAEL-SEAFKYWDG 128

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHG----LGELVAQM 176
           ++     +  M+ E K      +F++ N    G GHI +DY ++L  G    + E++  M
Sbjct: 129 KTTSALADSYMSQEAKDCMANGVFTVGNYFYGGVGHICVDYGKILRKGFKGIIAEVIEAM 188

Query: 177 QQHCQQQPE----NHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
            +  ++ P+      FY A ++   A+     RYA+ A  MAA   +  R+ ELL IA  
Sbjct: 189 SKMDKKDPDYIKKQQFYNAVVISYSAAINFAHRYAQKARDMAAAELNPTRKAELLQIAAN 248

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
                ++    F++ACQ FW++ I++Q ESN  S+S GRFDQYM P+ +      ++  F
Sbjct: 249 CERVPENGATNFYEACQSFWFIQIMVQIESNGHSISPGRFDQYMYPYLKEDKNISKE--F 306

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +EL++ +W+K NDI   R   SA+ FAG+       +GG  E G  A N +S++C+DA 
Sbjct: 307 AQELVDCIWIKLNDINKTRDEISAQAFAGYAVFQNLCVGGQNEEGLDATNEISYMCMDAT 366

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V+LP P+  +R        FL++  E  R G G+P ++NDEV++PA +NRGV+L DAR
Sbjct: 367 AHVKLPAPSFSIRVWQGTPDEFLLRACEVARLGLGVPAMYNDEVIIPALVNRGVTLRDAR 426

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENE-GNAAL-----------TYEG 460
           +Y ++GCVE   P +T G HD A FN+ KV+EI L+  + GN  L           + + 
Sbjct: 427 NYCIIGCVEPQCPNKTEGWHDAAFFNVAKVLEITLNNGKVGNKQLGPITGDITTFKSIDD 486

Query: 461 LLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFS 520
                + ++ +++  +VE  N  D  H + AP+P LS+ + DC+ +G+ + +GGA YNF+
Sbjct: 487 FYAAFKKQMEYFVYYLVEADNCVDYAHAERAPLPFLSAMVDDCIGRGKSVQEGGAIYNFT 546

Query: 521 GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANF-------------------- 560
           G Q  GIA+  DS++A++  VFE + +  D+L + L ANF                    
Sbjct: 547 GPQAFGIADTGDSVYAIQKHVFEDKTIEMDQLKAALDANFGHTGVNTVSTSNNNADVTEM 606

Query: 561 -------------ATPEGEKVRARLINRFEK---------------------YGNDIDEV 586
                         + +  ++++R+ + F                       +GNDIDEV
Sbjct: 607 QIYEAVKRILSNSGSIDISEIQSRISSEFTSPKTTVSGDFDNIRRLLESTPCFGNDIDEV 666

Query: 587 DNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGG 646
           D ++ +  + YC EVEKY NPRGG F  G Y VSA+V  G  V A PDGR A   LAD G
Sbjct: 667 DMVARKCAQIYCFEVEKYTNPRGGQFQAGVYPVSANVLFGKDVAALPDGRLAKTPLAD-G 725

Query: 647 LSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQ 706
           +SP  G+D  GPTA   SV+KLD+ + SNGTL N KF P+ + G+ GL+  A  +R++  
Sbjct: 726 VSPRAGKDCAGPTAAANSVAKLDHFVASNGTLYNQKFLPSAVAGDTGLQNFASVIRSYFD 785

Query: 707 LKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
            K  H+QFNV++   L +AQ+ P++Y  LVVRVAGYSA F  L+KE+QDDII RT H L
Sbjct: 786 HKGMHVQFNVIDKQLLLDAQKHPENYKDLVVRVAGYSAQFTVLAKEVQDDIINRTEHSL 844



>ref|YP_531045.1| pyruvate formate-lyase [Rhodopseudomonas palustris BisB18]
 gb|ABD86726.1| pyruvate formate-lyase [Rhodopseudomonas palustris BisB18]
          Length = 847

 Score =  521 bits (1343), Expect = e-146
 Identities = 310/843 (36%), Positives = 453/843 (53%), Gaps = 84/843 (9%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T R+ RLK  +      +  ERA+L T ++++TEG P ILRRAKA   I  ++ ++IR +
Sbjct: 10  TERVMRLKNVILNAKPFVESERAVLVTDAYKETEGLPAILRRAKAAEKIFNNLPVTIRAD 69

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G  T +PR+  + PE    W+ KE +   TR  D F I +E      E  F YW  
Sbjct: 70  ELIVGAITKRPRSTEICPEFSFDWVEKEFETMATRVADPFQIPKETAAELHEA-FKYWPG 128

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHG----LGELVAQM 176
           ++  D  +  M+ E K      +F++ N    G GH+ +DY ++L  G    + E+V  M
Sbjct: 129 KTTSDLASSYMSQEAKDCIAAGVFTVGNYFYGGVGHVCVDYGKVLKIGFRGIITEVVLAM 188

Query: 177 QQHCQQQP----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
           ++  +  P    +  FY A ++   A+     RYA  AE +A   ++A R+ ELL IA+ 
Sbjct: 189 EKLDRMDPGYIKKQQFYNAVIISYTAAINFAHRYAVKAEELAQTESNATRKAELLQIAKN 248

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
                ++    F++ACQ FW++  +LQ ES+  S+S GRFDQYM PF     +   +  F
Sbjct: 249 CARVPEYGASNFYEACQSFWFLQALLQIESSGHSISPGRFDQYMYPFLAADKSISRE--F 306

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +EL++ +W+K ND+   R   SA+ FAG+       +GG TE G  A N +SF+C++A 
Sbjct: 307 AQELIDCIWIKLNDVNKTRDGGSAQAFAGYAVFQNLCVGGQTEEGLDATNDVSFMCMEAT 366

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V LP P+  +R        FL +  E +R G G+P ++NDEV+VP+  NRGVSL DAR
Sbjct: 367 AHVALPAPSFSIRVWQGTPDDFLYRACEVVRLGLGVPAMYNDEVIVPSLQNRGVSLRDAR 426

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENE---------GNAALTY---EG 460
           DY +VGCVE     +T G HD A FN+ KV+EI L+                L++   + 
Sbjct: 427 DYGIVGCVEPQAIHKTEGWHDAAFFNVAKVLEITLNNGRVGDKQVGPASGELLSFRCIDD 486

Query: 461 LLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFS 520
           +    + +I +++  +VE  N  D+ H +  P+P +S+ + DC+ +G+ + +GGA YNF+
Sbjct: 487 VFAAFQKQIEYFVRYLVEADNCVDLAHGERCPLPFVSALVEDCIGRGKSLQEGGALYNFT 546

Query: 521 GVQGIGIANLSDSL----------------------------------HALKGMVFEQQR 546
           G Q  G+A+  DS+                                  HA  G  + +++
Sbjct: 547 GPQAFGVADTGDSVYAIQKNVFEDKKITLGELKAALDANFGRPVGESAHADAGTNYTEEQ 606

Query: 547 LSFDELLSVLKANFATP----EGEKVRA--------------------RLINRFEKYGND 582
           + F  +  VL ++ +T     +G+   A                    RL+     +GND
Sbjct: 607 V-FAAVKKVLNSSGSTDVSALKGKVYSALAGANGAKSGGASSSYDALHRLLEATPAFGND 665

Query: 583 IDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQL 642
           I EVD ++    + YC EVEKY NPRGG F  G Y VSA+V  G  V A PDGRFA   L
Sbjct: 666 IHEVDMVARRCAQIYCLEVEKYTNPRGGQFQAGIYPVSANVLFGKDVAALPDGRFAKAPL 725

Query: 643 ADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLR 702
           ADG +SP  G+D  GPTA   SV+KLD+ + SNGTL N KF PA L G++GL+  A  +R
Sbjct: 726 ADG-VSPRQGKDVNGPTAAANSVAKLDHFIASNGTLYNQKFLPAALAGDSGLQNFASLVR 784

Query: 703 AFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTA 762
           ++   K  H+QFNVV+  TL +AQ+ P+ +  LVVRVAGYSA FV L+KE+QDDII RT 
Sbjct: 785 SYFDHKGMHVQFNVVDRQTLLDAQREPEKHNDLVVRVAGYSAQFVVLAKEVQDDIISRTE 844

Query: 763 HQL 765
             L
Sbjct: 845 QTL 847



>ref|ZP_01352562.1| pyruvate formate-lyase [Clostridium phytofermentans ISDg]
 gb|EAT24085.1| pyruvate formate-lyase [Clostridium phytofermentans ISDg]
          Length = 867

 Score =  517 bits (1331), Expect = e-144
 Identities = 307/852 (36%), Positives = 453/852 (53%), Gaps = 96/852 (11%)

Query: 4   RISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEEL 63
           RI +L  AL+    EI  +RA+L T S++QTEGEP+I RR+KA  +I++++ + IR+ EL
Sbjct: 14  RIQKLMDALYEKMPEIESKRAVLITESYQQTEGEPIISRRSKAFEHIVKNLPVVIRENEL 73

Query: 64  IAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRS 123
           I G+ TV  R     PE    WL+ ELD   TR  D F ISEE K+  R+ +  YW+ ++
Sbjct: 74  IVGSATVAERGCQTFPEFSFDWLIAELDTVATRTADPFYISEEAKKELRK-VHSYWKGKT 132

Query: 124 MKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLN---HGLGELVAQMQQH 179
             +  +  M  E K A    +F+  N    G GHI + Y +++     G+ + V   ++ 
Sbjct: 133 TSELADYYMAPETKLAMEHNVFTPGNYFYNGVGHITVQYDKVIAIGYEGIKDEVLSRKKE 192

Query: 180 CQQQPENH-----FYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISR 234
                 ++     FY A +   +++  +  RYA  A+ +A +C D +RR+ELL I+    
Sbjct: 193 LHLGDADYASRLTFYDAVIRSCDSAILYAKRYAAEAKRLALSCQDEKRRQELLMISSNCE 252

Query: 235 HNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-DAAFL 293
                   TF++ACQ FW++ ++LQ E++  S+S GRFDQY+  +Y+     G       
Sbjct: 253 RVPAKGANTFYEACQAFWFVQLLLQIEASGHSISPGRFDQYLYSYYKADREAGRITGEQA 312

Query: 294 KELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQ 353
           +E+++ ++VK NDI   R  +SA  FAG+      ++GG   NGR A N LSF+ L+A  
Sbjct: 313 QEIIDCIFVKLNDINKCRDAASAEGFAGYGMFQNMIVGGQDSNGRDATNELSFMILEASI 372

Query: 354 SVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARD 413
              LPQP+L +R         L+K AE  R G G+P  +NDEV++PA +N+G +LE+AR+
Sbjct: 373 HTMLPQPSLSIRVWNGSPHDLLIKAAEVTRTGIGLPAYYNDEVIIPAMMNKGATLEEARN 432

Query: 414 YSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAAL------------TYEGL 461
           Y+++GCVE  +PG+T G HD A FN+ + +E+       N  L            T+E  
Sbjct: 433 YNIIGCVEPQVPGKTDGWHDAAFFNMCRPLEMVFSSGYENGKLVGAPTGSVENFTTFEAF 492

Query: 462 LEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSG 521
            +  + ++ ++I+L+V   N  DI H    P+P  SS + DC+ +G  + +GGA+YNF+G
Sbjct: 493 YDAYKTQMEYFISLLVNADNSIDIAHAKLCPLPFESSMVEDCIGRGLCVQEGGAKYNFTG 552

Query: 522 VQG----------------------IGIANLSDSLHALKGMVF------EQQRLSFDELL 553
            QG                      + I  L ++L    GM        E   LS D +L
Sbjct: 553 PQGFGIANMTDSLYAIKKLVYEEGKVSITELKEALLHNFGMTTKNAGLKESSHLSIDIIL 612

Query: 554 S--------------------------------VLKANFATPEGEKVRA----------- 570
           +                                  K N  +P   +V             
Sbjct: 613 AQQITVQIVKELKERGKEPSEKEIEQILKTVLEAKKENTESPISTRVSENTSNHSRYQEI 672

Query: 571 -RLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVV 629
            ++I    KYGNDI E+D  + E+   Y K ++KY+NPRGG F  G Y VSA+VPLG   
Sbjct: 673 LQMIEVLPKYGNDILEIDEFAREIAYTYTKPLQKYKNPRGGVFQAGLYPVSANVPLGEQT 732

Query: 630 GATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLE 689
           GATPDGR A   +ADG + P  G+D +GPTA   SV++LD+   +NGTL N KF P+ L+
Sbjct: 733 GATPDGRLANTPIADG-VGPAPGRDTKGPTAAANSVARLDHMDATNGTLYNQKFHPSALQ 791

Query: 690 GEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVEL 749
           G  GL K    +RAF   K  H+QFNVV+ +TL +AQ+ P++Y  LVVRVAGYSA F  L
Sbjct: 792 GRGGLEKFVALIRAFFDQKGMHVQFNVVSRETLLDAQKHPENYKHLVVRVAGYSALFTTL 851

Query: 750 SKEIQDDIIRRT 761
           S+ +QDDII RT
Sbjct: 852 SRSLQDDIINRT 863



>ref|ZP_01372386.1| pyruvate formate-lyase [Desulfitobacterium hafniense DCB-2]
 gb|EAT49340.1| pyruvate formate-lyase [Desulfitobacterium hafniense DCB-2]
          Length = 796

 Score =  509 bits (1312), Expect = e-142
 Identities = 283/785 (36%), Positives = 443/785 (56%), Gaps = 30/785 (3%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           ++ RI  L+  + A   EI ++RALL T S+ +T G   I RRAKA   +L +++I I D
Sbjct: 17  VSERIRALREEIVATVPEIFMDRALLVTESYEETFGSSYIYRRAKALEKVLLNMDICIND 76

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G+   KPR   + PE D  +L+ E+D+F  R  D+F ISE++K I R+ ++  W+
Sbjct: 77  KELIVGSYAGKPRGCQVFPEYDMKFLVDEMDEFALRQADKFTISEDNKAIARQ-IYEKWK 135

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQ-- 178
             ++ D       +E   A+   IF +     G GH++++Y +++  GL   + ++++  
Sbjct: 136 GNTITDQALNLFPEEAAKASQQLIFLLTCLGSGIGHMLVNYEKVIQKGLAGFMLEIEELE 195

Query: 179 ------HCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
                   +   +  +YQ+  ++ +A  K   R++ LA   A    D QR+EELL IAE 
Sbjct: 196 NGLDICDPEYNDKKTYYQSLTIVCQAVCKFAGRFSLLALAQAEKTADPQRKEELLQIAEN 255

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
            R       Q FWQA Q  W++ ++L  ESN  S+S GRFDQYM P+Y        D   
Sbjct: 256 CRRVPAQPAQNFWQALQALWFVQLVLHLESNGHSVSPGRFDQYMYPYYAAET----DKDA 311

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +ELL  LW+K  ++  +R+  S+  F G+P     ++GG   NG SAVN LS LCL+A 
Sbjct: 312 CEELLHCLWLKFFELNKIRNKVSSVVFGGYPMFQNIVVGGQNANGESAVNELSHLCLEAT 371

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V LPQP+L VR        F+    E + +GTG+P +FNDEV++P  L  G ++E+AR
Sbjct: 372 AKVHLPQPSLSVRWFYGCPEEFIRHALEVVSYGTGMPALFNDEVIIPNMLQLGYTIEEAR 431

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEG--------------NAALTY 458
           DY+++GC E+++P +T         N+LK++E+ + +                  +  T+
Sbjct: 432 DYAIIGCTEMNVPHKTEPFLTGGFLNILKILELTIFDGFDPVSQTQQAFQSGCVESFTTF 491

Query: 459 EGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYN 518
           E   +    ++S+Y+   V   NI D  H    P P  S  +SDCLE G+   +GGARYN
Sbjct: 492 EEFQKAYYEQLSYYLRQHVTCDNILDALHGKICPTPFESMLLSDCLENGKSNLEGGARYN 551

Query: 519 FSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEK 578
            + +Q +G+AN++DSL  +K +++ ++ L++++L + L+ N+   + E +R R+IN   K
Sbjct: 552 TTTLQLVGMANVADSLATIKKLIYVEKSLTWNQLKAALQNNY--EDDELLRQRIINHVPK 609

Query: 579 YGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFA 638
           YGND D VD +  +++ H C+E  KY++PR G +    YT++ +V   S VGATPDGR  
Sbjct: 610 YGNDHDFVDRLGRDVVYHCCREAAKYRSPRNGTYNIAVYTLATNVLWASKVGATPDGRKM 669

Query: 639 GEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLA 698
           G  LADGG+S   G D  G TA+  SV K+D        LLN++ +P++   E   +K  
Sbjct: 670 GSVLADGGVSCSHGMDKNGLTALFNSVRKIDPYKPLGSALLNIRLSPSSF-NETDFQKTV 728

Query: 699 DFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDII 758
           D +++F   K QH+QFNV + + LR+AQ+ P+ Y  L+VRVAG+S  F  +   +Q+DII
Sbjct: 729 DVVKSFFMNKGQHVQFNVFDVNALRDAQKNPEKYPLLMVRVAGFSVLFTTIETILQEDII 788

Query: 759 RRTAH 763
            RT H
Sbjct: 789 NRTLH 793



>ref|NP_070278.1| pyruvate formate-lyase 2 (pflD) [Archaeoglobus fulgidus DSM 4304]
 pdb|2F3O|A Chain A, Crystal Structure Of A Glycyl Radical Enzyme From
           Archaeoglobus Fulgidus
 pdb|2F3O|B Chain B, Crystal Structure Of A Glycyl Radical Enzyme From
           Archaeoglobus Fulgidus
 gb|AAB89800.1| pyruvate formate-lyase 2 (pflD) [Archaeoglobus fulgidus DSM 4304]
          Length = 776

 Score =  496 bits (1277), Expect = e-138
 Identities = 283/764 (37%), Positives = 434/764 (56%), Gaps = 33/764 (4%)

Query: 19  ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAGIMS 78
           +S+ER  LYT S +QTEGEP+I+R+AKA  ++LE++ I I D ELI G     P   I+ 
Sbjct: 19  LSVERCRLYTESMKQTEGEPMIIRQAKALKHVLENIPIQILDSELIVGTMLPNPPGAIIF 78

Query: 79  PEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKA 138
           PE     ++ ELD  P R  +R  + EED ++ REE+ PYW++++++ F    M D ++ 
Sbjct: 79  PEGVGLRIINELDSLPNRETNRLMVDEEDAKVLREEIAPYWQRKTIEAFAFPLMPDIMQI 138

Query: 139 ATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQQPEN--------HFYQ 190
                +F + +   G  H+ ++YP LL  G    + + ++  +   E+         FYQ
Sbjct: 139 LYTGSVFVLTEI-AGISHVAVNYPYLLRRGFRWFLEESERRIRALEESGVYEGEKYSFYQ 197

Query: 191 AALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQACQL 250
           AA ++ EA   + LRY++LAE +A +  D +RREELL IAEI R     KP+TFW+A Q 
Sbjct: 198 AAKIVSEAVINYGLRYSKLAEELAES-EDGERREELLKIAEICRKVPAEKPETFWEAVQF 256

Query: 251 FWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG---EDAAFLKELLESLWVKCNDI 307
            W +   L  E+   ++S+GR DQY+ PF++  + +G    + AF  ++L +LW+K N+I
Sbjct: 257 VWLVQSALHQENYEQAISMGRIDQYLYPFFKKDIGEGRINRELAF--DILANLWIKTNEI 314

Query: 308 VLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTN 367
           V    +   +YF+G  T     +GG    G  A N L++L L+    ++L QPN+ VR N
Sbjct: 315 VPAFDSLLEQYFSGQATNQAVTIGGCDIYGNDATNELTYLMLEVTDRLRLRQPNVHVRIN 374

Query: 368 ALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGR 427
                 FL + AE I  G     +F D+  V A  N  V   DA +Y+  GCVE++  G 
Sbjct: 375 KGSPESFLKRLAEAISSGCNNLALFFDDAAVKALKNAEVDDRDALNYTTDGCVEIAPFGN 434

Query: 428 TYGLHDIAMFNLLKVMEICLHEN-----------EGNAALTYEGLLEQIRAKISHYITLM 476
           ++   D A+ N+ K +E  L+E            +       E LLE++R ++SH + L+
Sbjct: 435 SFTSSDAALINVAKALEYALNEGVDLQFGYEFGAKTEKPKFLEDLLEKLREQVSHIVKLV 494

Query: 477 VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHA 536
           V GSN+    + +  P PLLS  + DC EKG D++ GGARYNF+G+Q +GIA++ DSL A
Sbjct: 495 VRGSNVLSYANAEVKPTPLLSLCVEDCFEKGVDVSRGGARYNFTGIQAVGIADVGDSLVA 554

Query: 537 LKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRH 596
           ++G +      S D+++   + NF    G +   +L+ +  KYGND D  D  +  +L  
Sbjct: 555 IEGAL--NAGYSMDDIVEACRKNFV---GYEKLHKLLLQSPKYGNDDDAADKYTKMVLEW 609

Query: 597 YCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQ 656
           YC+EV +++N RGG F  G Y ++ +V  G    A P GR +GE L + G+SP  G D +
Sbjct: 610 YCEEVNRHRNFRGGKFAAGCYPMTTNVGFGFFTSALPSGRKSGEPL-NPGVSPSTGMDRE 668

Query: 657 GPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNV 716
           G TAV+ S SKL    L NG  L +  +   L GE G   +   +++  +L + H+QFN+
Sbjct: 669 GVTAVINSASKLSYENLPNGASLTINLSSDVL-GEKGDAVIEALIKSSMELGVMHVQFNI 727

Query: 717 VNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRR 760
           +  D LR+AQQ P+ Y  L+VRVAG+SA+FVELS+ +Q+++IRR
Sbjct: 728 LKEDLLRKAQQEPEKYRWLLVRVAGWSAYFVELSRPVQEEVIRR 771



>ref|NP_756397.1| hypothetical protein c4537 [Escherichia coli CFT073]
 ref|YP_859768.1| putative pyruvate formate-lyase [Escherichia coli APEC O1]
 gb|AAN82971.1|AE016769_86 Putative conserved protein [Escherichia coli CFT073]
 gb|ABJ03644.1| putative pyruvate formate-lyase [Escherichia coli APEC O1]
          Length = 850

 Score =  480 bits (1236), Expect = e-133
 Identities = 291/846 (34%), Positives = 441/846 (52%), Gaps = 88/846 (10%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T+R+ RL+  +      +  ERA+L T ++++TE  P I+RRAK    I   + ++IR +
Sbjct: 10  TDRVVRLRNMILTAKPYVESERAVLATEAYKETEQLPAIMRRAKVVEKIFNQLPVTIRPD 69

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G  T+ PR+  + PE    W+ KE +    R  D F I ++  +   E  F YW  
Sbjct: 70  ELIVGAVTINPRSTEICPEFSYDWVEKEFETMEHRIADPFVIPKKTAQELHEA-FKYWPG 128

Query: 122 RSMKDFINGQMTDEVKAATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
           ++        M++  K +  + +F++ N    G GH+ +DY ++L  G   ++ ++ +  
Sbjct: 129 KTTSALAASYMSEGTKESMASGVFTVGNYFFGGVGHVSVDYGKVLKIGFRGIINEVSRAL 188

Query: 181 QQ----QP----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEI 232
           +     +P    +  FY A L+   A+ +   RYAE A  +A   ++  R+ EL  IA+ 
Sbjct: 189 ESLDRTEPGYIKKEQFYNAVLISYNAAIRFAHRYAEEASRLAQQESNPTRKRELEQIAQN 248

Query: 233 SRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAF 292
                ++   TFW+ACQ FW++  +LQ ES+  S+S GRFDQYM P+ ++  +   +  F
Sbjct: 249 CTRVPEYGATTFWEACQTFWFIQSMLQIESSGHSISPGRFDQYMYPYLESDKSISRE--F 306

Query: 293 LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAY 352
            +EL++  W+K NDI   R   SA+ FAG+        GG TE+GR A N LS++C++A 
Sbjct: 307 AQELVDCCWIKLNDINKTRDEVSAQAFAGYAVFQNLCCGGQTEDGRDATNDLSYMCMEAT 366

Query: 353 QSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDAR 412
             V+LPQP+  +R        FL +  E +R G G+P ++NDEV++PA  NRG+SL DAR
Sbjct: 367 AHVRLPQPSFSIRVWQGTPDEFLYRACELVRMGLGVPAMYNDEVIIPALQNRGISLRDAR 426

Query: 413 DYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENE-GNAAL-----------TYEG 460
           DY ++GCVE   P RT G HD A FN+ KV+EI L+    GN  L           + E 
Sbjct: 427 DYCIIGCVEPQAPHRTEGWHDAAFFNVAKVLEITLNNGRVGNKQLGPVTGELTQFTSMED 486

Query: 461 LLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFS 520
                + +++H++  +VE  N  DI H +  P+P LS+ + DC+ +G+ + +GGA YNF+
Sbjct: 487 FYTAFQKQMAHFVHQLVEACNSVDIAHGERCPLPFLSALVDDCIGRGKSLQEGGAIYNFT 546

Query: 521 GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYG 580
           G Q  G+A+  DS++A++  VFE ++LS  EL S L ANF  P G           +   
Sbjct: 547 GPQAFGVADTGDSVYAIQKQVFEDRKLSLSELKSALDANFGYPVGANPHTPAA---KSSL 603

Query: 581 NDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSY------TVSAHVPLGSVVGATP- 633
           N+ D  D +   + +H   +    +N      T GS       T+S H  +  ++  TP 
Sbjct: 604 NEQDIYDVVKRIIEQHGALDPAAIKNEVYRQLTSGSAAPVQSGTMSRHEEIRRILENTPC 663

Query: 634 ------------------------------DGRFAG---------------EQLADG--- 645
                                          G+F                   L DG   
Sbjct: 664 FGNDIDDVDLVARKCALIYCQEVEKYTNPRGGQFQAGIYPVSANVLFGKDVAALPDGRLA 723

Query: 646 ------GLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLAD 699
                 G+SP  G+D  GPTA   SV+KLD+ + SNGTL N KF P++L GE GLR  + 
Sbjct: 724 KEPLADGVSPRQGKDTLGPTAAANSVAKLDHFIASNGTLYNQKFLPSSLAGENGLRNFSG 783

Query: 700 FLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIR 759
            +R +   K  H+QFNV++ +TL EAQ+ P+ +  LVVRVAGYSA +V L+KE+QDDII 
Sbjct: 784 LIRHYFDKKGMHVQFNVIDRNTLIEAQKNPEQHQDLVVRVAGYSAQWVVLAKEVQDDIIS 843

Query: 760 RTAHQL 765
           RT  QL
Sbjct: 844 RTEQQL 849



>ref|ZP_01362669.1| Pyruvate formate-lyase [Clostridium sp. OhILAs]
 gb|EAT29715.1| Pyruvate formate-lyase [Clostridium sp. OhILAs]
          Length = 789

 Score =  477 bits (1227), Expect = e-132
 Identities = 295/795 (37%), Positives = 461/795 (57%), Gaps = 44/795 (5%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T RI++LK +       I +ERA+ +T SH++TEGE +ILRRAKA   + + V ++I D+
Sbjct: 3   TERIAQLKKSYINTKPSICVERAIAFTNSHKKTEGEAMILRRAKAFKEVCKAVPVTIFDQ 62

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G   +  R+G + PE    W+ KE+D F  R QD + I EE K I + ++FPYW  
Sbjct: 63  ELIVGTPGIYKRSGFICPEFSWQWVEKEMDDFQNRSQDAYLIGEEQKEILKNDIFPYWVG 122

Query: 122 RSMKDFINGQMTDEV-KAATNTQIFSINQTDKGQ-GHIIIDYPRLLN-HGLGELVAQMQQ 178
           +S+++    ++ +E  K A +T I   +   +   G I  DY  ++   G G + A+  +
Sbjct: 123 KSLEEAFLSRIPEETRKIAVDTGIVDNDSKWRSAVGEITPDYQDIIFVKGFGGIRAEAME 182

Query: 179 HCQQ-QPEN-------HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
             ++ +P +       +FYQA +   +       RY++ A  MA    D +R+EEL+ I 
Sbjct: 183 KLRKLEPLSAEALEKINFYQAIIESCDGIINLAKRYSKKALEMAEAEKDVKRKEELIRIH 242

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG--- 287
           ++ ++  ++ P++F++A Q+ W++ +      N+ +L+LGRFDQYM PFY+  L  G   
Sbjct: 243 QVCKNIPENPPRSFYEAIQMVWFVQLGSILSENSLALNLGRFDQYMYPFYEKDLKDGKIK 302

Query: 288 EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFL 347
           E+ A  +EL+E+LW+K ++ V   S ++A+YFAG+ +     +GG   +G  A N +S++
Sbjct: 303 EEEA--QELIEALWLKLSEWVWAISKNTAQYFAGYNSFQNLTVGGRKRDGSDATNTISYM 360

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
            L A ++V+  QP L VR +      FL+   + IR GTG P + ND +     L  G+S
Sbjct: 361 ALKASKNVKTHQPGLSVRIHPDSPQEFLIAVCDLIREGTGFPAVHNDRIGSQMLLAAGLS 420

Query: 408 LEDARDYSVVGCVELSIPG-RTYGLHDIAM-FNLLKVMEICLHENEGNAALTYE--GLLE 463
            EDARD+S  GCV   +P  R  G    A+  NL   +E  L  N G + +T E  GL E
Sbjct: 421 PEDARDWSNCGCV---VPHFRKVGEWTSAVNINLAAALEYAL--NSGKSRITKEQMGLKE 475

Query: 464 Q--------------IRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
           +                 ++S+ I   V  S I    H +  P P LS+ +  C++KG D
Sbjct: 476 ENHLGMNSFKDIKDHFYRQLSNLIKHGVISSVIAQQIHTEMVPRPFLSTLVDGCMDKGVD 535

Query: 510 ITDGGARYNFSGV-QGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
           ++ GGA YN   V  GIGIA++++SL A+K +V+E ++++ ++L S L  N+   + E +
Sbjct: 536 LSKGGAFYNIGPVLTGIGIADVANSLMAIKKLVYEDKKITLNQLNSALNNNWE--DQEDL 593

Query: 569 RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
           R   +N   KYGNDIDEVD I+ E+   Y KE++KY++  G  F      +S ++P GSV
Sbjct: 594 RKEALN-CPKYGNDIDEVDQIAVEISDFYNKEIKKYKDYFGVPFNSAFMGISNYIPAGSV 652

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
           +GATPDGR +G+ L +G +SP  G D   PTA ++S +K+++ + + GTLLNVK +P  L
Sbjct: 653 IGATPDGRRSGDPLTEG-VSPHAGTDLTSPTAAMRSAAKINHDIHTGGTLLNVKLSPELL 711

Query: 689 EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
           + +  L  LA  +RA+ +L   H+QFNV++ DTLR+AQ+ P+ Y  L+VRVAGYS  FV 
Sbjct: 712 KTDKSLVNLASLIRAYFELGAFHVQFNVISVDTLRKAQENPEAYRDLLVRVAGYSTQFVN 771

Query: 749 LSKEIQDDIIRRTAH 763
           LSKE+QD II+RT +
Sbjct: 772 LSKEVQDAIIQRTTY 786



>ref|ZP_00365816.1| COG1882: Pyruvate-formate lyase [Streptococcus pyogenes M49 591]
          Length = 805

 Score =  476 bits (1226), Expect = e-132
 Identities = 304/798 (38%), Positives = 442/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A   +  +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAETAS-TERQAELLEIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG-EDA 290
           I          TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G E  
Sbjct: 250 ICDKVPYEPAATFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 291 AFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
           A + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 ASIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ RL+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGRLTPEELWHALESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ  P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQNHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|ZP_01476143.1| hypothetical protein VEx2w_02001343 [Vibrio sp. Ex25]
          Length = 807

 Score =  476 bits (1225), Expect = e-132
 Identities = 305/805 (37%), Positives = 450/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALF-ANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +  RI   K+AL    T  I  ERA  YT +++  E +PVI++RA A    L    I I+
Sbjct: 6   LPERIKAHKSALVNIVTPPICTERAEAYTRAYQANEDKPVIVQRALALQEHLSTRTIWIK 65

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  K RA  + PE    W+  E+D+   RP   FA+SEEDK+     + PYW
Sbjct: 66  HDELIVGNQASKVRAAPIFPEYTVRWIEAEIDELADRPGAGFAVSEEDKQSIHA-ITPYW 124

Query: 120 EKRSMKDFINGQMTDEVKAA-TNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE +    +T I +      G  H+ +D  ++L  G+  L+ +++Q
Sbjct: 125 RGKTVQDRCYGLFTDEQQEILASTIIKAEGNMTSGDAHLAVDNEKILKVGMNGLLDEVRQ 184

Query: 179 HCQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
           H             +  FY++  ++L A Q+HI+ YA+LA  MA N T  +R+ EL TIA
Sbjct: 185 HRANNDVSTYEGLKKEQFYKSVEIVLLAIQEHIVSYADLALEMAQNETRPERKAELETIA 244

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-D 289
           E  RH A H P  FWQA QL +++ ++LQ ESN  S+S GR DQ++  +Y   L  G  +
Sbjct: 245 ENCRHVAFHAPTNFWQALQLSYFVQLMLQIESNGHSVSFGRMDQFLNDYYVRDLESGAMN 304

Query: 290 AAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG--LTENGR--SAVNVLS 345
            AF  ELL+S W+K  ++  +RS + ++  AG P      +GG  L ENG    AVN LS
Sbjct: 305 KAFALELLQSCWLKLLEVNKIRSGAHSKASAGSPLYQNVCIGGQKLNENGEPEDAVNPLS 364

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +  ++  FLM   E I+ G G+P   NDE+V+P F+  G
Sbjct: 365 WAILESCGQLRSTQPNLSVRYHEGLNQEFLMGCIEVIKCGFGMPAFNNDEIVIPEFIKLG 424

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHEN----EGNAALTYEG 460
           V  EDA +Y+ +GC+E ++PG+  Y    ++  N  +++   L+E      G A L ++ 
Sbjct: 425 VEKEDAYNYASIGCIETAVPGKWGYRCTGMSFINFARILLAALNEGVDATTGKAFLPHDK 484

Query: 461 LL--------EQIRA----KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
            L        +Q+ A    +I +Y    +E   + D      A     SS + DCL +G+
Sbjct: 485 SLAKGNFESFDQVTASWAEQIRYYTRKSIEIDTVVDSVLEQQAQDIFCSSLVDDCLARGK 544

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            + +GGA+Y++ SG+Q +GIANL +SL A+K +VFE+ ++S  EL   L+ +F   E E+
Sbjct: 545 TVKEGGAKYDWVSGLQ-VGIANLGNSLAAIKHLVFEEAQISQTELAKALEEDFDGIENEQ 603

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A+  + Y  E+ ++ N      P GG +  G+ ++SA
Sbjct: 604 LRQRLINFAPKYGNDDDYVDQLLADAYQVYIDELAQFVNTRHGRGPIGGGYYAGTSSISA 663

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  SV K+    +  G LLN 
Sbjct: 664 NVPFGASTMATPDGRKAKTPLAEGA-SPASGSDRLGPTAVYNSVGKIQANKILGGVLLNQ 722

Query: 682 KFTPATLEGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K +PA +  E    KL+  +R  F   K  H+Q+N+V+  TL  A++ P+ Y  LVVRVA
Sbjct: 723 KLSPAAVASEGDKLKLSMLIRTFFNHHKGWHVQYNIVSRKTLLAAKKNPEQYRDLVVRVA 782

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H+L
Sbjct: 783 GYSAFFTALSPDAQDDIIARTEHEL 807



>ref|NP_801077.1| putative pyruvate formate lyase [Vibrio parahaemolyticus RIMD
           2210633]
 dbj|BAC62910.1| putative pyruvate formate lyase [Vibrio parahaemolyticus RIMD
           2210633]
          Length = 807

 Score =  476 bits (1224), Expect = e-132
 Identities = 304/805 (37%), Positives = 451/805 (56%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALF-ANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +  RI   K+AL    T  I  ERA  YT +++  E +PVI++RA A    L    I I+
Sbjct: 6   LPERIKAHKSALVNIVTPPICTERAEAYTRAYQANEDKPVIVQRALALQEHLRTRTIWIK 65

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  K RA  + PE    W+  E+D+   RP   F++SEEDK+     + PYW
Sbjct: 66  HDELIVGNQASKVRAAPIFPEYTVRWIEAEIDELADRPGAGFSVSEEDKQSIHA-ITPYW 124

Query: 120 EKRSMKDFINGQMTDEVKAA-TNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE +    +T I +      G  H+ +D  ++L  G+  L+ +++Q
Sbjct: 125 RGKTVQDRCYGLFTDEQQEILASTIIKAEGNMTSGDAHLAVDNEKILKIGMNGLLNEVRQ 184

Query: 179 HCQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
           H             +  FY+A  ++L A Q+H++ YA+LA  MA N T  +R+ EL TIA
Sbjct: 185 HRANNDVSTYEGLKKEQFYKAVEIVLLAIQEHMVSYADLALEMAQNETRPERKAELETIA 244

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-D 289
           E  RH A H P  FWQA QL +++ ++LQ ESN  S+S GR DQ++  +Y   L  G  +
Sbjct: 245 ENCRHVAFHAPTNFWQALQLSYFVQLMLQIESNGHSVSFGRMDQFLNDYYVRGLESGAMN 304

Query: 290 AAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG--LTENGR--SAVNVLS 345
            AF  ELL+S W+K  ++  +RS + ++  AG P      +GG  L ENG    AVN LS
Sbjct: 305 KAFALELLQSCWLKLLEVNKIRSGAHSKASAGSPLYQNVCIGGQKLNENGEPEDAVNPLS 364

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +  ++  FLM   E I+ G G+P   NDE+V+P F+  G
Sbjct: 365 WAILESCGQLRSTQPNLSVRYHEGLNQEFLMGCIEVIKCGFGMPAFNNDEIVIPEFIKLG 424

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHEN----EGNAALTYEG 460
           V   DA +Y+ +GC+E ++PG+  Y    ++  N  +++   L+E      G A L+++ 
Sbjct: 425 VEKADAYNYASIGCIETAVPGKWGYRCTGMSFINFARILLAALNEGVDATTGKAFLSHDK 484

Query: 461 LL--------EQIRA----KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
            L        EQ+ A    +I +Y    +E   + D      A     SS + DCL +G+
Sbjct: 485 SLAKGNFESFEQVTASWAEQIRYYTRKSIEIDTVVDSVLEQQAQDIFCSSLVDDCLARGK 544

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            + +GGA+Y++ SG+Q +GIANL +SL A+K +VFE+ ++S  EL   L+ +F   E E+
Sbjct: 545 TVKEGGAKYDWVSGLQ-VGIANLGNSLAAIKHLVFEEAQISQTELAKALEEDFDGIENEQ 603

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A+  + Y  E+ ++ N      P GG +  G+ ++SA
Sbjct: 604 LRQRLINFAPKYGNDDDYVDQLLADAYQVYIDELAQFVNTRHGRGPIGGGYYAGTSSISA 663

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  SV K+    +  G LLN 
Sbjct: 664 NVPFGASTMATPDGRKAKTPLAEGA-SPASGSDRLGPTAVYNSVGKIQANKILGGVLLNQ 722

Query: 682 KFTPATLEGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K +PA +  E    KL+  +R  F   K  H+Q+N+V+ +TL  A++ P+ Y  LVVRVA
Sbjct: 723 KLSPAAVASEGDKLKLSMLIRTFFNHHKGWHVQYNIVSRETLLAAKKNPEQYRDLVVRVA 782

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H+L
Sbjct: 783 GYSAFFTALSPDAQDDIIARTEHEL 807



>ref|YP_601373.1| Formate acetyltransferase [Streptococcus pyogenes MGAS2096]
 gb|ABF36829.1| Formate acetyltransferase [Streptococcus pyogenes MGAS2096]
          Length = 805

 Score =  475 bits (1223), Expect = e-132
 Identities = 303/798 (37%), Positives = 443/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A      +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG-EDA 290
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G E  
Sbjct: 250 ICDKVPYEPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 291 AFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
           A + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 ASIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ +L+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGQLTPEELWQALESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|YP_281195.1| formate acetyltransferase [Streptococcus pyogenes MGAS6180]
 gb|AAX72840.1| formate acetyltransferase [Streptococcus pyogenes MGAS6180]
          Length = 805

 Score =  474 bits (1220), Expect = e-132
 Identities = 302/798 (37%), Positives = 442/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMAHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A      +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DTIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ RL+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGRLTPEELWHALESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|ZP_00722160.1| COG1882: Pyruvate-formate lyase [Escherichia coli F11]
 ref|YP_668754.1| putative formate acetyltransferase 3 [Escherichia coli 536]
 gb|ABG68855.1| putative formate acetyltransferase 3 [Escherichia coli 536]
          Length = 810

 Score =  474 bits (1220), Expect = e-132
 Identities = 309/807 (38%), Positives = 442/807 (54%), Gaps = 47/807 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            + H      +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLTIA
Sbjct: 188 RRSHINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQ 464
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L    G  A + +  L Q
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEG--GRDATSGKVFLPQ 485

Query: 465 IRA------------------KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEK 506
            +A                  +I +Y    +E   + D    +     L S+ + DC+E+
Sbjct: 486 AKALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIER 545

Query: 507 GRDITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEG 565
            + I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     
Sbjct: 546 AKSIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTH 604

Query: 566 EKVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTV 619
           E++R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++
Sbjct: 605 EQLRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPIGGNYYAGTSSI 664

Query: 620 SAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLL 679
           SA+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LL
Sbjct: 665 SANVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLL 723

Query: 680 NVKFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVR 738
           N K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVR
Sbjct: 724 NQKLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVR 783

Query: 739 VAGYSAFFVELSKEIQDDIIRRTAHQL 765
           VAGYSAFF  LS + QDDII RT H L
Sbjct: 784 VAGYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_269993.1| putative pyruvate formate-lyase 2 [Streptococcus pyogenes M1 GAS]
 gb|AAK34714.1| putative pyruvate formate-lyase 2 [Streptococcus pyogenes M1 GAS]
          Length = 805

 Score =  474 bits (1219), Expect = e-131
 Identities = 302/798 (37%), Positives = 441/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A      +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DTIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ RL+ +EL   L+++FA   GE +R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGRLTPEELWKALESDFAGERGEDIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|ZP_00925323.1| COG1882: Pyruvate-formate lyase [Escherichia coli 101-1]
          Length = 832

 Score =  474 bits (1219), Expect = e-131
 Identities = 287/829 (34%), Positives = 433/829 (52%), Gaps = 88/829 (10%)

Query: 19  ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAGIMS 78
           +  ERA+L T ++++TE  P I+RRAK    I   + ++IR +ELI G  T+ PR+  + 
Sbjct: 9   VESERAVLATEAYKETEQLPAIMRRAKVVEKIFNQLPVTIRPDELIVGAVTINPRSTEIC 68

Query: 79  PEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKA 138
           PE    W+ KE +    R  D F I ++  +   E  F YW  ++        M++  K 
Sbjct: 69  PEFSYDWVEKEFETMEHRIADPFVIPKKTAQELHEA-FKYWPGKTTSALAASYMSEGTKE 127

Query: 139 ATNTQIFSI-NQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQ----QP----ENHFY 189
           +  + +F++ N    G GH+ +DY ++L  G   ++ ++ +  +     +P    +  FY
Sbjct: 128 SMASGVFTVGNYFFGGVGHVSVDYGKVLKIGFRGIINEVSRALESLDRTEPGYIKKEQFY 187

Query: 190 QAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQACQ 249
            A L+   A+ +   RYAE A  +A   ++  R+ EL  IA+      ++   TFW+ACQ
Sbjct: 188 NAVLISYNAAIRFAHRYAEEASRLAQQESNPTRKRELEQIAQNCTRVPEYGATTFWEACQ 247

Query: 250 LFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLKELLESLWVKCNDIVL 309
            FW++  +LQ ES+  S+S GRFDQYM P+ ++  +   +  F +EL++  W+K NDI  
Sbjct: 248 TFWFIQSMLQIESSGHSISPGRFDQYMYPYLESDKSISRE--FAQELVDCCWIKLNDINK 305

Query: 310 LRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNAL 369
            R   SA+ FAG+        GG TE+GR A N LS++C++A   V+LPQP+  +R    
Sbjct: 306 TRDEVSAQAFAGYAVFQNLCCGGQTEDGRDATNDLSYMCMEATAHVRLPQPSFSIRVWQG 365

Query: 370 IDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTY 429
               FL +  E +R G G+P ++NDEV++PA  NRG+SL DARDY ++GCVE   P RT 
Sbjct: 366 TPDEFLYRACELVRMGLGVPAMYNDEVIIPALQNRGISLRDARDYCIIGCVEPQAPHRTE 425

Query: 430 GLHDIAMFNLLKVMEICLHENE-GNAAL-----------TYEGLLEQIRAKISHYITLMV 477
           G HD A FN+ KV+EI L+    GN  L           + E      + +++H++  +V
Sbjct: 426 GWHDAAFFNVAKVLEITLNNGRVGNKQLGPVTGELTQFTSMEDFYTAFQKQMAHFVHQLV 485

Query: 478 EGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHAL 537
           E  N  DI H +  P+P LS+ + DC+ +G+ + +GGA YNF+G Q  G+A+  DS++A+
Sbjct: 486 EACNSVDIAHGERCPLPFLSALVDDCIGRGKSLQEGGAIYNFTGPQAFGVADTGDSVYAI 545

Query: 538 KGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAELLRHY 597
           +  VFE ++LS  EL S L ANF  P G           +   N+ D  D +   + +H 
Sbjct: 546 QKQVFEDRKLSLSELKSALDANFGYPVGANPHTPAA---KSSLNEQDIYDVVKRIIEQHG 602

Query: 598 CKEVEKYQNPRGGYFTPGSY------TVSAHVPLGSVVGATP------------------ 633
             +    +N      T GS       T+S H  +  ++  TP                  
Sbjct: 603 ALDPAAIKNEVYRQLTSGSAAPVQSGTMSRHEEIRRILENTPCFGNDIDDVDLVARKCAL 662

Query: 634 -------------DGRFAG---------------EQLADG---------GLSPMLGQDAQ 656
                         G+F                   L DG         G+SP  G+D  
Sbjct: 663 IYCQEVEKYTNPRGGQFQAGIYPVSANVLFGKDVAALPDGRLAKEPLADGVSPRQGKDTL 722

Query: 657 GPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNV 716
           GPTA   SV+KLD+ + SNGTL N KF P++L GE GLR  +  +R +   K  H+QFNV
Sbjct: 723 GPTAAANSVAKLDHFIASNGTLYNQKFLPSSLAGENGLRNFSGLIRHYFDKKGMHVQFNV 782

Query: 717 VNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           ++ +TL EAQ+ P+ +  LVVRVAGYSA +V L+KE+QDDII RT  QL
Sbjct: 783 IDRNTLIEAQKNPEQHQDLVVRVAGYSAQWVVLAKEVQDDIISRTEQQL 831



>ref|NP_608068.1| putative pyruvate formate-lyase 2 [Streptococcus pyogenes MGAS8232]
 gb|AAL98567.1| putative pyruvate formate-lyase 2 [Streptococcus pyogenes MGAS8232]
          Length = 805

 Score =  473 bits (1218), Expect = e-131
 Identities = 302/798 (37%), Positives = 442/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A   +  +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAQLARELAETASP-ERQAELLDIAC 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I          TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAATFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DTIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ RL+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGRLTPEELWQALESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|YP_407215.1| putative formate acetyltransferase [Shigella boydii Sb227]
 gb|ABB65387.1| putative formate acetyltransferase [Shigella boydii Sb227]
          Length = 810

 Score =  473 bits (1217), Expect = e-131
 Identities = 307/805 (38%), Positives = 440/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL IA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT---ENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG T        AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQTLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLH----ENEGNAAL---- 456
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L        GN  L    
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGNVFLPQEK 487

Query: 457 --------TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
                    ++ +++    +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_665553.1| putative pyruvate formate-lyase [Streptococcus pyogenes MGAS315]
 ref|NP_803009.1| putative pyruvate formate-lyase 2 [Streptococcus pyogenes SSI-1]
 gb|AAM80356.1| putative pyruvate formate-lyase [Streptococcus pyogenes MGAS315]
 dbj|BAC64842.1| putative pyruvate formate-lyase 2 [Streptococcus pyogenes SSI-1]
          Length = 805

 Score =  473 bits (1217), Expect = e-131
 Identities = 301/798 (37%), Positives = 442/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A      +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DSIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ +L+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGQLTPEELWQALESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|ZP_00698439.1| COG1882: Pyruvate-formate lyase [Shigella boydii BS512]
          Length = 810

 Score =  473 bits (1217), Expect = e-131
 Identities = 307/805 (38%), Positives = 440/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL IA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT---ENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG T        AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQTLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLH----ENEGNAAL---- 456
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L        GN  L    
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGNVFLPQEK 487

Query: 457 --------TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
                    ++ +++    +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGTIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|YP_599421.1| Formate acetyltransferase [Streptococcus pyogenes MGAS10270]
 gb|ABF34877.1| Formate acetyltransferase [Streptococcus pyogenes MGAS10270]
          Length = 805

 Score =  472 bits (1214), Expect = e-131
 Identities = 301/798 (37%), Positives = 441/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMAHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A      +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DTIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ +L+ +EL   L+++FA   GE +R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGQLTPEELWHALESDFAGERGEDIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|NP_687365.1| formate acetyltransferase [Streptococcus agalactiae 2603V/R]
 ref|NP_734788.1| hypothetical protein gbs0319 [Streptococcus agalactiae NEM316]
 ref|YP_329053.1| formate acetyltransferase 2 [Streptococcus agalactiae A909]
 ref|ZP_00782093.1| pyruvate formate-lyase [Streptococcus agalactiae H36B]
 ref|ZP_00786930.1| pyruvate formate-lyase [Streptococcus agalactiae CJB111]
 gb|AAM99237.1|AE014206_17 formate acetyltransferase [Streptococcus agalactiae 2603V/R]
 emb|CAD45964.1| unknown [Streptococcus agalactiae NEM316]
 gb|ABA45174.1| formate acetyltransferase 2 [Streptococcus agalactiae A909]
 gb|EAO74236.1| pyruvate formate-lyase [Streptococcus agalactiae CJB111]
 gb|EAO79199.1| pyruvate formate-lyase [Streptococcus agalactiae H36B]
          Length = 818

 Score =  472 bits (1214), Expect = e-131
 Identities = 304/798 (38%), Positives = 444/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+   +  +      I  ERA+L T ++++ + +P +L+RA     ILE + I I D
Sbjct: 25  LTERMYSYRDKVLDKKPFIDAERAILVTEAYQKHQEKPNVLKRAYMLQNILEKMTIYIDD 84

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +I GN+    +   + PE    +++ ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 85  ETMIVGNQASSDKDAPIFPEYTLEFVVNELDLFEKRDGDVFYITEETKEQIRN-IAPFWE 143

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL  GL     + ++ 
Sbjct: 144 NNNLRARAGVMLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEEGLIGFEKKARKA 203

Query: 180 CQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                  +PE+    HFY + L+ +EA + +  R+A LA+  A    +A+RR+ELL IA 
Sbjct: 204 KADLDLTKPESIDKYHFYDSILITIEAVKTYAERFAILAKKQAKTA-NAKRRQELLDIAS 262

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I      +  +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ ++ L  G +  
Sbjct: 263 ICERVPYYPAETFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKSDLEAGRETE 322

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T +   AVN LSFL L 
Sbjct: 323 DSIVERLTNLWIKTITINKVRSQAHTFSSAGSPLYQNVTIGGQTRHKEDAVNPLSFLVLK 382

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GVS ED
Sbjct: 383 SVAQTHLPQPNLTVRYHANLDKSFMNEAIEVMKLGFGMPAFNNDEIIIPSFIKKGVSEED 442

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I +++    A+             +
Sbjct: 443 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKVLLITMNDGIDPASGKRFAPSYGHFTQM 502

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
           T    L++   K   Y+T M V   N  DI      P  L S+   DC+ +G+ + +GGA
Sbjct: 503 TSYKELKEAWDKTLRYLTRMSVIVENAIDISLEREVPDILCSALTDDCIGRGKHLKEGGA 562

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE++RL+  E+   L++++A P GE++R  LIN
Sbjct: 563 VYDYISGLQ-VGIANLSDSLAALKKLVFEEKRLTTLEVWQALQSDYAGPRGEEIRQMLIN 621

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y +E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 622 EAPKYGNDDDYADSLVRECYDVYVEEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 681

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 682 TLATPDGRHAGTPLAE-GCSPSHNMDKKGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 740

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E   +KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 741 AKEEDKQKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 800

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 801 VLSKATQDDIIARTEHAL 818



>ref|ZP_00780073.1| pyruvate formate-lyase [Streptococcus agalactiae 18RS21]
 gb|EAO63315.1| pyruvate formate-lyase [Streptococcus agalactiae 18RS21]
          Length = 818

 Score =  471 bits (1213), Expect = e-131
 Identities = 304/798 (38%), Positives = 444/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+   +  +      I  ERA+L T ++++ + +P +L+RA     ILE + I I D
Sbjct: 25  LTERMYSYRDKVLDKKPFIDAERAILVTEAYQKHQEKPNVLKRAYMLQNILEKMTIYIDD 84

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +I GN+    +   + PE    +++ ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 85  ETMIVGNQASSDKDAPIFPEYTLEFVVNELDLFEKRDGDVFYITEETKEQIRN-IAPFWE 143

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL  GL     + ++ 
Sbjct: 144 NNNLRARAGVMLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEEGLIGFEKKARKA 203

Query: 180 CQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                  +PE+    HFY + L+ +EA + +  R+A LA+  A    +A+RR+ELL IA 
Sbjct: 204 KADLDLTKPESIDKYHFYDSILITIEAVKTYAERFAILAKKQAKTA-NAKRRQELLDIAS 262

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I      +  +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ ++ L  G +  
Sbjct: 263 ICERVPYYPAETFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKSDLEAGRETE 322

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T +   AVN LSFL L 
Sbjct: 323 DSIVERLTNLWIKTITINKVRSQAHTFSSAGSPLYQNVTIGGQTRHKEDAVNPLSFLVLK 382

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GVS ED
Sbjct: 383 SVAQTHLPQPNLTVRYHANLDKSFMNEAIEVMKLGFGMPAFNNDEIIIPSFIKKGVSEED 442

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I +++    A+             +
Sbjct: 443 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKVLLITMNDGIDPASGKRFAPSYGHFTQM 502

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
           T    L++   K   Y+T M V   N  DI      P  L S+   DC+ +G+ + +GGA
Sbjct: 503 TSYKELKEAWDKTLRYLTRMSVIVENAIDISLEREVPDILCSALTDDCIGRGKHLKEGGA 562

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE++RL+  E+   L++++A P GE++R  LIN
Sbjct: 563 VYDYISGLQ-VGIANLSDSLAALKKLVFEEKRLTTLEVWQALQSDYAGPRGEEIRQMLIN 621

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y +E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 622 EAPKYGNDDDYADSLVRECYDVYVEEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 681

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 682 TLATPDGRHAGTPLAE-GCSPSHNMDKKGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 740

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E   +KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 741 AKEEDKQKLIALLRTFFNRLYGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 800

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 801 VLSKATQDDIIARTEHAL 818



>ref|ZP_01588855.1| pyruvate formate-lyase [Enterobacter sp. 638]
 gb|EAV84823.1| pyruvate formate-lyase [Enterobacter sp. 638]
          Length = 810

 Score =  471 bits (1212), Expect = e-131
 Identities = 300/805 (37%), Positives = 445/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +T+RI   KTAL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L    + I+
Sbjct: 9   LTDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHMDKPIPVRRALALAHHLAKRTLWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  + + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHD-ICPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL  + A++ +
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLETGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGMRAKVAE 187

Query: 179 H--------CQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
                          + F +A  ++L+A   HI R+A LA  MA+N     RR+ELL +A
Sbjct: 188 RRTRINLTVLDDLHGDQFLKAIDIVLDAVSLHIQRFASLAREMASNEIRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   P+TFWQA QL +++ +ILQ ESN  S+S  R DQY+ PFY+    L Q  
Sbjct: 248 ENCDVIAHQPPKTFWQALQLCYFIQLILQIESNGHSVSFARMDQYLYPFYRRDVELDQSL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           +     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 NREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLVNGEAMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+  F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVISEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           V  EDA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L +++
Sbjct: 428 VEKEDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAAMEGGRDATSGKVFLPQDK 487

Query: 452 GNAALTY---EGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +   E ++E    +I +Y    +E   + D    +  P  L SS + DC+E+ +
Sbjct: 488 ALSAGNFDNFEQVMESWDNQIRYYTRKSIEIEYVVDTMLEENVPDILCSSLVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I +GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  ++     E+
Sbjct: 548 SIKEGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGTIGQQQLAAALADDYEGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y +E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDSVDLLLARAYQTYIEELKQYHNPRYGRGPIGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAATMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTEAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE ++  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENDSDRQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKRHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHTL 810



>ref|YP_603331.1| Formate acetyltransferase [Streptococcus pyogenes MGAS10750]
 gb|ABF38787.1| Formate acetyltransferase [Streptococcus pyogenes MGAS10750]
          Length = 805

 Score =  471 bits (1212), Expect = e-131
 Identities = 301/798 (37%), Positives = 441/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A      +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIAR 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DSIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ + VS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKDVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGYGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ RL+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGRLTPEELWQSLESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|YP_539843.1| putative formate acetyltransferase 3 [Escherichia coli UTI89]
 ref|YP_851915.1| putative formate acetyltransferase 3 [Escherichia coli APEC O1]
 gb|ABE06312.1| putative formate acetyltransferase 3 [Escherichia coli UTI89]
 gb|ABJ00201.1| putative formate acetyltransferase 3 [Escherichia coli APEC O1]
          Length = 810

 Score =  471 bits (1212), Expect = e-131
 Identities = 306/805 (38%), Positives = 443/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLTIA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPIGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|YP_061061.1| Formate acetyltransferase [Streptococcus pyogenes MGAS10394]
 gb|AAT87878.1| Formate acetyltransferase [Streptococcus pyogenes MGAS10394]
          Length = 805

 Score =  471 bits (1212), Expect = e-131
 Identities = 301/798 (37%), Positives = 442/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R++  + A+      I  ERA+L T ++++ + +P  L+RA     ILE++ I I D
Sbjct: 12  LTDRMTHYREAVLDKKPYIDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIED 71

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 72  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWE 130

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL HGL     + +  
Sbjct: 131 NNNLRARCGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAA 190

Query: 180 CQQQ----PEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                   PEN    HFY +  ++++A + +  RYA+LA  +A   +  +R+ ELL IA 
Sbjct: 191 KAALDLTIPENIDKYHFYDSVFIVIDAVKTYAKRYAKLARELAETASP-ERQAELLDIAC 249

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I          TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 250 ICDKVPYEPAATFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 309

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T + + AVN LS+L L 
Sbjct: 310 DTIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLR 369

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +    +LPQPNL VR +  +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS ED
Sbjct: 370 SVAQTKLPQPNLTVRYHKGLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEED 429

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I +++    A+              
Sbjct: 430 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDM 489

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L     A +     + V   N  D+G     P  L S+   DC+ +G+ + +GGA
Sbjct: 490 TSYEELKAAWDATLREITRMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGA 549

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE+ +L+ +EL   L+++FA   GE++R  LIN
Sbjct: 550 VYDYISGLQ-VGIANLSDSLAALKKLVFEEGQLTPEELWHALESDFAGERGEEIRQMLIN 608

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 609 DAPKYGNDDDYADSLVVEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKG 668

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 669 TLATPDGRHAGTPLAE-GCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTL 727

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 728 AKEEDKLKLMALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 787

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 788 VLSKATQDDIIERTEHTL 805



>ref|YP_309787.1| putative formate acetyltransferase [Shigella sonnei Ss046]
 gb|AAZ87552.1| putative formate acetyltransferase [Shigella sonnei Ss046]
          Length = 810

 Score =  471 bits (1212), Expect = e-131
 Identities = 307/805 (38%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL IA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT---ENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG T        AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQTLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_752838.1| Putative formate acetyltransferase 3 [Escherichia coli CFT073]
 gb|AAN79381.1|AE016757_285 Putative formate acetyltransferase 3 [Escherichia coli CFT073]
          Length = 810

 Score =  471 bits (1211), Expect = e-130
 Identities = 306/805 (38%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  + Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYHQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLTIA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPIGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_455377.1| putative formate acetyltransferase 3 [Salmonella enterica subsp.
           enterica serovar Typhi str. CT18]
 ref|NP_805809.1| putative formate acetyltransferase 3 [Salmonella enterica subsp.
           enterica serovar Typhi Ty2]
 pir||AG0602 formate C-acetyltransferase (EC 2.3.1.54) - Salmonella enterica
           subsp. enterica serovar Typhi (strain CT18)
 emb|CAD05289.1| putative formate acetyltransferase 3 [Salmonella enterica subsp.
           enterica serovar Typhi]
 gb|AAO69669.1| putative formate acetyltransferase 3 [Salmonella enterica subsp.
           enterica serovar Typhi Ty2]
          Length = 810

 Score =  470 bits (1210), Expect = e-130
 Identities = 305/805 (37%), Positives = 445/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   KTAL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L    I I+
Sbjct: 9   LSDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLAERTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   F++SEE+KRI  + + P+W
Sbjct: 69  HDELIVGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFSVSEENKRILHD-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL---VAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL +L   VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDDLRDKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L+A  +HI R+A LA  MA   +   RR+ELLTIA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLDAVSQHITRFAALARQMAGEESRESRRKELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCEVIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTE-NGR--SAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG    NG+   AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLINGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMAAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGVIGQQQLAAALADDFDGLPHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDSVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAATMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTGSILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  P TLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL +A++ P  Y  LVVRVA
Sbjct: 726 KLNPTTLENESDKQKLMVLLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|ZP_00908945.1| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052]
 gb|EAP60376.1| Pyruvate formate-lyase [Clostridium beijerincki NCIMB 8052]
          Length = 801

 Score =  470 bits (1210), Expect = e-130
 Identities = 292/799 (36%), Positives = 444/799 (55%), Gaps = 38/799 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R+   +  L      +S+ERA L T S+++   +P++LRRA     IL+++ I I D
Sbjct: 7   LTDRMHNFREELLNAKSMVSVERARLTTESYKEHADKPMVLRRALCLENILKNMTIFIED 66

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
             +IAGN+    R+  + PE    W++ ELD+F  R  D F I+EE K + RE + P+WE
Sbjct: 67  NSIIAGNQAESNRSAPIFPEYAMDWVINELDEFEKREGDIFYITEESKNVLRE-IAPFWE 125

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
            +++KD     M  E +   +  I         G  HI ++Y  +LN GL     + ++ 
Sbjct: 126 HKTLKDRGLAGMPAESRIFYDLGIIKAEGNITSGDAHIAVNYETVLNLGLINYKERTEKK 185

Query: 180 CQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
            ++          +++FY+A L++L+A      RYA+LA  +A   +D  R+EELL ++ 
Sbjct: 186 LKELDLTDYRNLNKSYFYRAILIVLDAVAAFAKRYADLALELAEKESDVNRKEELLEMSR 245

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG---E 288
           I      +  +TF +A Q  W ++++LQ ESN  SLS GR DQY+ PFY+  L  G   E
Sbjct: 246 ILNKVPYYPAETFHEAVQSLWIIHLVLQIESNGHSLSYGRMDQYLNPFYEKDLKLGKITE 305

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLC 348
           D+A   ELL +LW+K   I  +RS S  R+ AG P      +GG T + +  VN LS+L 
Sbjct: 306 DSA--TELLTNLWLKTFTINKIRSWSHTRFSAGSPLYQNVTVGGQTVDKKDEVNPLSYLI 363

Query: 349 LDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSL 408
           L +    +LPQPNL VR +  +   F+ +  E +R G G+P   +DEV++P+F+ +GV  
Sbjct: 364 LKSVAQTKLPQPNLTVRYHKGLSDDFMKECIEVVRLGFGMPAFNSDEVIIPSFIEKGVDE 423

Query: 409 EDARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHEN---EGNAAL-------- 456
           +DA +YS +GCVE+++PG+  Y    ++  N  K + I L++    E    L        
Sbjct: 424 KDAYNYSAIGCVEVAVPGKWGYRCTGMSFLNFPKSLLIALNDGVDPESGTKLCEGVGHFK 483

Query: 457 ---TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDG 513
              T++ +++     I  +    V   +  D+   +     L S+   DC+E+G ++ +G
Sbjct: 484 DMTTFDEVMKAWDKIIREFTRHSVIIDSCADLAIEEVTADVLCSALTDDCIERGLNLKEG 543

Query: 514 GARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLI 573
           GA Y+F     +GIANL DSL A+K  VFE +  +  ++   L  NF   +G++++  L+
Sbjct: 544 GAVYDFISDLQVGIANLGDSLAAIKKCVFEDKSFTQAQVWDALLNNFEGEDGKRIQDILL 603

Query: 574 NRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGS 627
           N   KYGND D +D +  E    Y  E++KY+N      P GG +  G+ ++SA+VP G+
Sbjct: 604 NDAPKYGNDDDYIDLLLREAYEIYIDEIKKYKNTRYGRGPIGGCYYAGTSSISANVPQGA 663

Query: 628 VVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPAT 687
              ATPDGR AGE LA+ G SP    D  GPTAV KSVSKL    ++ G LLN K TP  
Sbjct: 664 GTLATPDGRKAGEPLAE-GCSPSHAMDKNGPTAVFKSVSKLPTHDITGGVLLNQKVTPQM 722

Query: 688 LEGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFF 746
           L  E+   KL   +R  F +L+  H+Q+NVV+ DTL +AQ+ P+++  L+VRVAGYSAFF
Sbjct: 723 LSKESDREKLILLIRTFFNRLEGFHVQYNVVSRDTLLDAQKHPEEHRDLIVRVAGYSAFF 782

Query: 747 VELSKEIQDDIIRRTAHQL 765
             LSK+ QDDII RT   L
Sbjct: 783 NVLSKQTQDDIIERTEQVL 801



>ref|ZP_00703131.1| COG1882: Pyruvate-formate lyase [Escherichia coli E24377A]
          Length = 810

 Score =  470 bits (1210), Expect = e-130
 Identities = 304/805 (37%), Positives = 440/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-MCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLT+A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLH----ENEGNAAL---- 456
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L        G   L    
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 457 --------TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
                    ++ +++    +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEIMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|ZP_00720244.1| COG1882: Pyruvate-formate lyase [Escherichia coli E110019]
          Length = 810

 Score =  470 bits (1209), Expect = e-130
 Identities = 305/805 (37%), Positives = 443/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLT+A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATRGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|ZP_00710729.1| COG1882: Pyruvate-formate lyase [Escherichia coli B171]
 ref|ZP_00717142.1| COG1882: Pyruvate-formate lyase [Escherichia coli B7A]
 ref|ZP_00729076.1| COG1882: Pyruvate-formate lyase [Escherichia coli E22]
          Length = 810

 Score =  470 bits (1209), Expect = e-130
 Identities = 305/805 (37%), Positives = 443/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLT+A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>gb|EAY48848.1| pyruvate formate-lyase [Escherichia coli B]
          Length = 810

 Score =  469 bits (1207), Expect = e-130
 Identities = 306/805 (38%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL IA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELKQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFEGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDMLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_786017.1| formate C-acetyltransferase [Lactobacillus plantarum WCFS1]
 emb|CAD64868.1| formate C-acetyltransferase [Lactobacillus plantarum WCFS1]
          Length = 814

 Score =  469 bits (1207), Expect = e-130
 Identities = 297/798 (37%), Positives = 429/798 (53%), Gaps = 36/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T  + RL+ ++      +  ERA+L T ++RQ + E V + RAK   ++L+ + I I D
Sbjct: 20  LTPMMDRLRDSIIDAKPYVDPERAILTTETYRQHQDEQVDILRAKMLEHVLDKMSIFIED 79

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           + LI GN+  + R   + PE    W++ ELD F  RP D F I+E+ K   R  + P+W+
Sbjct: 80  DTLIVGNQARQNRWAPVFPEYSMNWVIDELDTFEKRPGDVFYITEKSKEELRA-IAPFWK 138

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++D       +  +   +  I   +     G GHI +DY  ++N GL     +++  
Sbjct: 139 HNTLEDRGYASFPEASRIFYDLGIIGADGNITSGDGHIAVDYKNVVNKGLKWYEDRIKTA 198

Query: 180 C--------QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                     QQ + +FY+A L++++A      RYA+LA   A N T A R+ +L  IA+
Sbjct: 199 LANLDLTDFNQQKQYYFYKAGLIVIDAIHNFAKRYAQLASKQAQNTTSATRKAQLEKIAQ 258

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-DA 290
           I          +F++A Q  W +++ LQ ESN  S+S GR DQY+ PFY+  L  G  DA
Sbjct: 259 ILNKVPYEPANSFYEAIQAVWLVHLTLQIESNGHSVSYGRLDQYLAPFYEHDLKTGAIDA 318

Query: 291 AFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
               ELL +L +K   I  +RS     + AG P      +GG T +G+ AVN  S+L L 
Sbjct: 319 NGATELLTNLCLKTLTINKVRSWQHTEFSAGSPLYQNITIGGQTPDGKDAVNPTSYLILR 378

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           A     LPQPNL VR +  +   F+ +  E I+ G G+P   NDE+++P+F+ RGV  ED
Sbjct: 379 AIAQAHLPQPNLTVRYHHGLSDKFMRECVEVIKQGLGMPAFNNDEIIIPSFIRRGVKKED 438

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFN----LLKVMEICLHENEGNAAL--------- 456
           A +YS +GCVE +IPG+  Y    ++  N    LL +M   +    G   L         
Sbjct: 439 AYNYSAIGCVETAIPGKWGYRCTGMSFINFPRVLLLIMNGGIDPESGKRLLPDYGKFTDM 498

Query: 457 -TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +++ L+      +       V   N CD+      P  L S    DC+ +G+ I +GGA
Sbjct: 499 TSFDQLMTAWDKALREMTRQSVIIENSCDLALEQNYPDILCSVLTDDCIGRGKTIKEGGA 558

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y+F SG+Q +GIANL+DSL A+K +VFE+++L+  +L   L  +FA  +GEK+R  LIN
Sbjct: 559 VYDFISGLQ-VGIANLADSLAAIKKLVFEEKKLTTTQLWHALTTDFADEDGEKIRQMLIN 617

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D VD++  E  + Y  E+ KY+N      P GG    G+ ++SA+V  G  
Sbjct: 618 DAPKYGNDDDYVDDLIVEAYKPYIDEIAKYKNTRYGRGPIGGLRYAGTSSISANVGQGHS 677

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR A   LA+ G SP    D  GPTAV KSVSKL    ++ G LLN K +P  L
Sbjct: 678 TLATPDGRHARTPLAE-GCSPEHAMDTDGPTAVFKSVSKLSTKDITGGVLLNQKMSPQIL 736

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             +    KL   LR  F +L   H+Q+N+V+ DTL +AQ  P  +  L+VRVAGYSAFFV
Sbjct: 737 RSDESCMKLVALLRTFFNRLHGYHVQYNIVSRDTLIDAQNHPDKHRDLIVRVAGYSAFFV 796

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSKE QDDII RT   L
Sbjct: 797 GLSKETQDDIIERTEQSL 814



>ref|ZP_00784845.1| pyruvate formate-lyase [Streptococcus agalactiae COH1]
 gb|EAO76404.1| pyruvate formate-lyase [Streptococcus agalactiae COH1]
          Length = 818

 Score =  469 bits (1207), Expect = e-130
 Identities = 303/798 (37%), Positives = 441/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+   +  +      I  ERA+L T ++++ + +P +L+RA     ILE + I I D
Sbjct: 25  LTERMYSYRDKVLDKKPFIDAERAILVTEAYQKHQEKPNVLKRAYMLQNILEKMTIYIDD 84

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +I GN+    +   + PE    +++ ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 85  ETMIVGNQASSDKDAPIFPEYTLEFVVNELDLFEKRDGDVFYITEETKEQIRN-IAPFWE 143

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL  GL     + ++ 
Sbjct: 144 NNNLRARAGVMLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEEGLIGFEKKARKA 203

Query: 180 CQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                  +PE+    HFY + L+ +EA + +  R+A LA+  A    + +RR+ELL IA 
Sbjct: 204 KADLDLTKPESIDKYHFYDSILITIEAVKTYAERFAILAKKQAKTA-NTKRRQELLDIAS 262

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I      +  +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 263 ICERVPYYPAETFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 322

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T +   AVN LSFL L 
Sbjct: 323 DSIVERLTNLWIKTITINKVRSQAHTFSSAGSPLYQNVTIGGQTRHKEDAVNPLSFLVLK 382

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GVS ED
Sbjct: 383 SVAQTHLPQPNLTVRYHANLDKSFMNEAIEVMKLGFGMPAFNNDEIIIPSFIKKGVSEED 442

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I ++     A+             +
Sbjct: 443 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKVLLITMNNGIDPASGKRFAPSYGHFTQM 502

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
           T    L++   K   Y+T M V   N  DI      P  L S+   DC+ +G+ + +GGA
Sbjct: 503 TSYKELKEAWDKTLRYLTRMSVIVENAIDISLEREVPDILCSALTDDCIGRGKHLKEGGA 562

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE++RL+  E+   L++++A P GE++R  LIN
Sbjct: 563 VYDYISGLQ-VGIANLSDSLAALKKLVFEEKRLTTLEVWQALQSDYAGPRGEEIRQMLIN 621

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y +E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 622 EAPKYGNDDDYADSLVRECYDVYVEEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 681

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 682 TLATPDGRHAGTPLAE-GCSPSHNMDKKGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 740

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E   +KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 741 AKEEDKQKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 800

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 801 VLSKATQDDIIARTEHAL 818



>ref|YP_283106.1| formate acetyltransferase [Streptococcus pyogenes MGAS5005]
 gb|AAZ52361.1| formate acetyltransferase [Streptococcus pyogenes MGAS5005]
          Length = 790

 Score =  469 bits (1206), Expect = e-130
 Identities = 299/780 (38%), Positives = 432/780 (55%), Gaps = 37/780 (4%)

Query: 19  ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAGIMS 78
           I  ERA+L T ++++ + +P  L+RA     ILE++ I I DE LIAGN+    +   + 
Sbjct: 15  IDAERAILATEAYQKHQNKPANLKRAYMLQTILENMTIYIEDESLIAGNQASSNKDAPIF 74

Query: 79  PEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKA 138
           PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE  +++      + +EV+ 
Sbjct: 75  PEYTLEFVLNELDLFEKRDGDVFYITEETKQQLRD-IAPFWENNNLRARCGVLLPEEVQV 133

Query: 139 ATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQQ----PEN----HFY 189
              T  F +  + + G  H+ ++Y +LL HGL     + +          PEN    HFY
Sbjct: 134 YMETGFFGMEGKMNSGDAHLAVNYQKLLEHGLKGFEERARAAKAALDLTIPENIDKYHFY 193

Query: 190 QAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQACQ 249
            +  ++++A + +  RYA+LA  +A      +R+ ELL IA I         +TF +A Q
Sbjct: 194 DSVFIVIDAVKTYAKRYAKLARELAKTAKP-ERQAELLDIARICDKVPYEPAKTFAEAVQ 252

Query: 250 LFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA-FLKELLESLWVKCNDIV 308
             W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +    + E L +LW+K   I 
Sbjct: 253 SVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETEDTIVERLTNLWIKTLTIN 312

Query: 309 LLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNA 368
            +RS +     AG P      +GG T + + AVN LS+L L +    +LPQPNL VR + 
Sbjct: 313 KVRSQAHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLRSVAQTKLPQPNLTVRYHK 372

Query: 369 LIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGR- 427
            +D  F+ +  E ++ G G+P + NDE+++P+F+ +GVS EDA DYS +GCVE ++PG+ 
Sbjct: 373 GLDNTFMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVSEEDAYDYSAIGCVETAVPGKW 432

Query: 428 TYGLHDIAMFNLLKVMEICLHENEGNAA--------------LTYEGLLEQIRAKISHYI 473
            Y    ++  N  K++ I +++    A+               +YE L     A +    
Sbjct: 433 GYRCTGMSYINFPKILLITMNDGIDPASGKRFAKGHGHFKDMTSYEELKAAWDATLREIT 492

Query: 474 TLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNF-SGVQGIGIANLSD 532
            + V   N  D+G     P  L S+   DC+ +G+ + +GGA Y++ SG+Q +GIANLSD
Sbjct: 493 RMSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQ-VGIANLSD 551

Query: 533 SLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVDNISAE 592
           SL ALK +VFE+ RL+ +EL   L+++FA   GE +R  LIN   KYGND D  D++  E
Sbjct: 552 SLAALKKLVFEEGRLTPEELWKALESDFAGERGEDIRQMLINDAPKYGNDDDYADSLVVE 611

Query: 593 LLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGG 646
               Y  E+ KY N      P GG    G+ ++SA+V  G    ATPDGR AG  LA+ G
Sbjct: 612 AYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPLAE-G 670

Query: 647 LSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRA-FT 705
            SP    D +GPT+VLKSV+KL    +  G LLN K  P TL  E    KL   LR  F 
Sbjct: 671 CSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKLKLMALLRTFFN 730

Query: 706 QLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF  LSK  QDDII RT H L
Sbjct: 731 RLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSKATQDDIIERTEHTL 790



>ref|NP_286587.1| Pyruvate-formate lyase [Escherichia coli O157:H7 EDL933]
          Length = 810

 Score =  469 bits (1206), Expect = e-130
 Identities = 305/805 (37%), Positives = 443/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL +A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALARAMAATETRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA +Y+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYNYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +S  +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAISQQQLAAALANDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_706700.1| putative formate acetyltransferase [Shigella flexneri 2a str. 301]
 ref|NP_836477.1| putative formate acetyltransferase [Shigella flexneri 2a str.
           2457T]
 gb|AAN42407.1| putative formate acetyltransferase [Shigella flexneri 2a str. 301]
 gb|AAP16283.1| putative formate acetyltransferase [Shigella flexneri 2a str.
           2457T]
          Length = 810

 Score =  469 bits (1206), Expect = e-130
 Identities = 305/805 (37%), Positives = 441/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL +A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIMLVAVSEHIERFAALARAMAATETRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL      IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVHVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|YP_688342.1| putative formate acetyltransferase [Shigella flexneri 5 str. 8401]
 gb|ABF03037.1| putative formate acetyltransferase [Shigella flexneri 5 str. 8401]
          Length = 810

 Score =  468 bits (1205), Expect = e-130
 Identities = 305/805 (37%), Positives = 441/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL +A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALARAMAATETRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL      IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVHVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|NP_459820.1| putative pyruvate formate lyase [Salmonella typhimurium LT2]
 gb|AAL19779.1| putative pyruvate formate lyase [Salmonella typhimurium LT2]
          Length = 810

 Score =  468 bits (1205), Expect = e-130
 Identities = 302/805 (37%), Positives = 443/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   KTAL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L    I I+
Sbjct: 9   LSDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLAERTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   F++SEE+KRI  + + P+W
Sbjct: 69  HDELIVGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFSVSEENKRILHD-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLN---HGLGELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL    +GL + VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLYGLRDKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L+A  +HI R+A LA  MA   +   RR+ELLTIA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLDAVSQHITRFAALARQMAGEESRESRRKELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCEVIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLINGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMAAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGVIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAATMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTGSILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  P TLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL +A++ P  Y  LVVRVA
Sbjct: 726 KLNPTTLENESDKQKLMVLLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|ZP_00705044.1| COG1882: Pyruvate-formate lyase [Escherichia coli HS]
          Length = 810

 Score =  468 bits (1205), Expect = e-130
 Identities = 305/805 (37%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL IA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQML 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           +     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 EREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLIDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLAQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|ZP_00789518.1| pyruvate formate-lyase [Streptococcus agalactiae 515]
 gb|EAO71753.1| pyruvate formate-lyase [Streptococcus agalactiae 515]
          Length = 818

 Score =  468 bits (1205), Expect = e-130
 Identities = 303/798 (37%), Positives = 442/798 (55%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+   +  +      I  ERA+L T ++++ + +P +L+RA     ILE + I I D
Sbjct: 25  LTERMYSYRDKVLDKKPFIDAERAILVTEAYQKHQEKPNVLKRAYMLQNILEKMTIYIDD 84

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +I GN+    +   + PE    +++ ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 85  ETMIVGNQASSDKDAPIFPEYTLEFVVNELDLFEKRDGDVFYITEETKEQIRN-IAPFWE 143

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + +EV+    T  F +  + + G  H+ ++Y +LL  GL     + ++ 
Sbjct: 144 NNNLRARAGVMLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLEEGLIGFEKKARKA 203

Query: 180 CQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                  +PE+    HFY + L+ +EA + +  R+A LA+  A    +A+RR+ELL IA 
Sbjct: 204 KADLDLTKPESIDKYHFYDSILITIEAVKTYAERFAILAKKQAKTA-NAKRRQELLDIAS 262

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I      +  +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 263 ICERVPYYPAKTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 322

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T +   AVN LSFL L 
Sbjct: 323 DSIVERLTNLWIKTITINKVRSQAHTFSSAGSPLYQNVTIGGQTRHKEDAVNPLSFLVLK 382

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GVS ED
Sbjct: 383 SVAQTHLPQPNLTVRYHANLDKSFMNEAIEVMKLGFGMPAFNNDEIIIPSFIKKGVSEED 442

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I ++     A+             +
Sbjct: 443 AYDYSAIGCVETAVPGKWGYRCTGMSYINFPKVLLITMNNGIDPASGKRFAPSYGHFTQM 502

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
           T    L++   K   Y+T M V   N  DI      P  L S+   +C+ +G+ + +GGA
Sbjct: 503 TSYKELKEAWDKTLRYLTRMSVIVENAIDISLEREVPDILCSALTDNCIGRGKHLKEGGA 562

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL ALK +VFE++RL+  E+   L++++A P GE++R  LIN
Sbjct: 563 VYDYISGLQ-VGIANLSDSLAALKKLVFEEKRLTTLEVWQALQSDYAGPRGEEIRQMLIN 621

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D++  E    Y +E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 622 EAPKYGNDDDYADSLVRECYDVYVEEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 681

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D +GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 682 TLATPDGRHAGTPLAE-GCSPSHNMDKKGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 740

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E   +KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 741 AKEEDKQKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 800

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 801 VLSKATQDDIIARTEHAL 818



>ref|ZP_00735320.1| COG1882: Pyruvate-formate lyase [Escherichia coli 53638]
          Length = 810

 Score =  468 bits (1203), Expect = e-130
 Identities = 304/805 (37%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELLT+A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLTMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
                 A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ANCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|YP_001004997.1| putative formate acetyltransferase [Yersinia enterocolitica subsp.
           enterocolitica 8081]
 emb|CAL10757.1| putative formate acetyltransferase [Yersinia enterocolitica subsp.
           enterocolitica 8081]
          Length = 810

 Score =  467 bits (1202), Expect = e-129
 Identities = 302/808 (37%), Positives = 445/808 (55%), Gaps = 49/808 (6%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           ++ R  + K AL    +  +  ERA+ YT  ++Q + +P+ +RRA A A+ L+   I I+
Sbjct: 9   LSERTKQHKNALIHIVKPPVCTERAVHYTEVYQQHQDKPLSVRRALALAHHLQQRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           ++ELI GN+  + RA  + PE    W+  E+D+   RP   F++SEEDK +  + L P+W
Sbjct: 69  NDELIIGNQASQLRAAPIFPEYTVSWIESEIDELADRPGAGFSVSEEDKAVLHQ-LCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE KA   T I         G  H+ +++P LL  GL  L +++  
Sbjct: 128 RGQTVQDRCYGMFTDEQKALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRSKVTS 187

Query: 179 HCQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
              +          +  F +A  + L A  +HI RYA +A  MA   T   RR EL  IA
Sbjct: 188 RRSRLQLTDWSDLHKEQFLKAIDISLAALSEHIERYAAVARQMAQEETRDWRRVELQKIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSL----TQ 286
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+  +    T 
Sbjct: 248 ENCELIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRLDQYLYPWYRRDVELENTL 307

Query: 287 GEDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT-ENGRS--AVNV 343
             + A   E+L S W+K  ++  +RS S ++  AG P      +GG     G+S  AVN 
Sbjct: 308 SREQAI--EMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLVQGKSIDAVNP 365

Query: 344 LSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLN 403
           LS+  L++   ++  QPNL VR +A I   FL    + IR G G+P   NDE+V+P F+ 
Sbjct: 366 LSYAVLESCGRLRSTQPNLSVRYHAGISDDFLDACVQVIRCGFGMPAFNNDEIVIPEFIK 425

Query: 404 RGVSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHE------------- 449
            GV  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L +             
Sbjct: 426 LGVEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEQGRDATSGQVFLPQ 485

Query: 450 ----NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLE 505
               ++GN +  +  ++ Q  A+I +Y    +E   + D    + A   + S+ + DC+E
Sbjct: 486 EQGLSKGNFS-DFSQVMAQWDAQIRYYTRKSIEIECVVDTVLEENAHDIVCSALVDDCIE 544

Query: 506 KGRDITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPE 564
           +G+ I  GGARY++ SG+Q +GIANL +SL A++ +VFEQQ +S  +L + L  +FA   
Sbjct: 545 RGKSIKQGGARYDWVSGLQ-VGIANLGNSLAAVRKLVFEQQLISQQQLATALANDFAGLN 603

Query: 565 GEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYT 618
           GE++R  LIN   KYGND+D+VD +     + Y  E+++Y N      P GG +  G+ +
Sbjct: 604 GEQLRQHLINSAPKYGNDVDDVDQLLVRAYQTYIDELKQYHNTRFGRGPIGGTYYAGTSS 663

Query: 619 VSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTL 678
           +SA+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  S+SKL    +  G L
Sbjct: 664 ISANVPFGAATMATPDGRKAHSPLAEGA-SPASGTDHLGPTAVFNSLSKLPTASILGGVL 722

Query: 679 LNVKFTPATLEGEAGLRKLADFLRAFTQLKL-QHIQFNVVNADTLREAQQRPQDYAGLVV 737
           LN K  P+TL+      KL   LR F +  L  H+Q+N+V+ +TL EA+Q P  Y  LVV
Sbjct: 723 LNQKLNPSTLDNPRDREKLMMMLRTFFEEYLGWHVQYNIVSRETLLEAKQHPDRYRDLVV 782

Query: 738 RVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           RVAGYSAFF  LS + QDDII RT H L
Sbjct: 783 RVAGYSAFFTALSPDAQDDIIARTEHTL 810



>ref|YP_215825.1| putative pyruvate formate lyase [Salmonella enterica subsp.
           enterica serovar Choleraesuis str. SC-B67]
 gb|AAX64744.1| putative pyruvate formate lyase [Salmonella enterica subsp.
           enterica serovar Choleraesuis str. SC-B67]
          Length = 810

 Score =  467 bits (1202), Expect = e-129
 Identities = 305/805 (37%), Positives = 443/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   KTAL    +  +  ERA  YT  ++Q   +P  +RRA A A+ L    I I+
Sbjct: 9   LSDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHLDKPTPVRRALALAHHLAERTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   F++SEE+KRI  + + P+W
Sbjct: 69  HDELIVGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFSVSEENKRILHD-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL---VAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL  L   VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRDKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L+A  +HI R+A LA  MA   +   RR+ELLTIA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLDAVSQHITRFAALARQMAGEESRESRRKELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCEVIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTE-NGR--SAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG    NG+   AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLINGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMAAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGVIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAATMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTGSILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  P TLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL +A++ P  Y  LVVRVA
Sbjct: 726 KLNPTTLENESDKQKLMVLLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|YP_402437.1| putative formate acetyltransferase [Shigella dysenteriae Sd197]
 gb|ABB60948.1| putative formate acetyltransferase [Shigella dysenteriae Sd197]
          Length = 810

 Score =  467 bits (1201), Expect = e-129
 Identities = 305/805 (37%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL +A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELKQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGVIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL EA++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS E Q+DII RT H L
Sbjct: 786 GYSAFFTALSPEAQNDIIARTEHML 810



>ref|NP_415344.1| predicted pyruvate formate lyase [Escherichia coli K12]
 ref|AP_001454.1| predicted pyruvate formate lyase [Escherichia coli W3110]
 sp|P75793|PFLF_ECOLI Putative formate acetyltransferase 3 (Pyruvate formate-lyase 3)
 gb|AAC73910.1| predicted pyruvate formate lyase [Escherichia coli K12]
 dbj|BAA35504.2| predicted pyruvate formate lyase [Escherichia coli W3110]
          Length = 810

 Score =  467 bits (1201), Expect = e-129
 Identities = 301/805 (37%), Positives = 441/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL  L  ++ +
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREEVAE 187

Query: 179 H--------CQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
                     +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL +A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL +A++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|ZP_00924764.1| COG1882: Pyruvate-formate lyase [Escherichia coli 101-1]
          Length = 810

 Score =  467 bits (1201), Expect = e-129
 Identities = 303/805 (37%), Positives = 442/805 (54%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   K AL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L +  I I+
Sbjct: 9   LSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   FA+SEE+KR+  E + P+W
Sbjct: 69  HDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHE-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL    E VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L A  +HI R+A LA  MAA  T   RR+ELL +A
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           D     E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 DREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLAQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAQTMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  PATLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL +A++ P  Y  LVVRVA
Sbjct: 726 KLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT H L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTEHML 810



>ref|YP_151135.1| putative formate acetyltransferase 3 [Salmonella enterica subsp.
           enterica serovar Paratyphi A str. ATCC 9150]
 gb|AAV77823.1| putative formate acetyltransferase 3 [Salmonella enterica subsp.
           enterica serovar Paratyphi A str. ATCC 9150]
          Length = 810

 Score =  466 bits (1200), Expect = e-129
 Identities = 304/805 (37%), Positives = 444/805 (55%), Gaps = 43/805 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI   KTAL    +  +  ERA  YT  ++Q   +P+ +RRA A A+ L    I I+
Sbjct: 9   LSDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLAERTIWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  + RA  + PE    W+ KE+D    RP   F++SEE+KRI  + + P+W
Sbjct: 69  HDELIVGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFSVSEENKRILHD-VCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL---VAQ 175
             ++++D   G  TDE K    T I         G  H+ +++P LL  GL  L   VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRDKVAE 187

Query: 176 MQQHC-----QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +        +      F +A  ++L+A  +HI R+A LA  MA   +   RR+ELLTIA
Sbjct: 188 RRSRINLTVLEDLHGEQFLKAIDIVLDAVSQHITRFAALARQMAGEKSRESRRKELLTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L Q  
Sbjct: 248 ENCEVIAHEPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTE-NGR--SAVNVLS 345
           D     ELL S W+K  ++  +RS S ++  AG P      +GG    NG+   AVN LS
Sbjct: 308 DREHAIELLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLINGQPMDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A +   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVM-------------EICLHENE 451
           +  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM             ++ L + +
Sbjct: 428 IEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEK 487

Query: 452 GNAALTYEGLLEQIRA---KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             +A  +    E + A   +I +Y    +E   + D    +     L S+ + DC+E+ +
Sbjct: 488 ALSAGNFNNFDEVMAAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAK 547

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
            I  GGA+Y++ SG+Q +GIANL +SL A+K +VFEQ  +   +L + L  +F     E+
Sbjct: 548 SIKQGGAKYDWVSGLQ-VGIANLGNSLAAVKKLVFEQGVIGQQQLAAALANDFDGLTHEQ 606

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPR------GGYFTPGSYTVSA 621
           +R RLIN   KYGND D VD + A   + Y  E+++Y NPR      GG +  G+ ++SA
Sbjct: 607 LRQRLINGAPKYGNDDDSVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISA 666

Query: 622 HVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNV 681
           +VP G+   ATPDGR A   LA+G  SP  G D  GPTAV+ SV KL    +  G LLN 
Sbjct: 667 NVPFGAATMATPDGRKAHTPLAEGA-SPASGTDHLGPTAVIGSVGKLPTGSILGGVLLNQ 725

Query: 682 KFTPATLEGEAGLRKLADFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA 740
           K  P TLE E+  +KL   LR F ++ K  HIQ+N+V+ +TL +A++ P  Y  LVVRVA
Sbjct: 726 KLNPTTLENESDKQKLMVLLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVA 785

Query: 741 GYSAFFVELSKEIQDDIIRRTAHQL 765
           GYSAFF  LS + QDDII RT + L
Sbjct: 786 GYSAFFTALSPDAQDDIIARTENML 810



>ref|ZP_00825734.1| COG1882: Pyruvate-formate lyase [Yersinia mollaretii ATCC 43969]
          Length = 810

 Score =  464 bits (1194), Expect = e-129
 Identities = 297/806 (36%), Positives = 443/806 (54%), Gaps = 45/806 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +++RI + K AL    +  +  ERA  YT +++Q + +P+ +RRA A A+ L+   + I+
Sbjct: 9   LSDRIKQHKNALIHIVKPPVCTERARHYTEAYQQHQDKPLPVRRALALAHHLQQRTVWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           ++ELI GN+  + RA  + PE    W+  E+D+   RP   F++SEEDK +  + + P+W
Sbjct: 69  NDELIIGNQASQLRAAPIFPEYTVGWIESEIDELADRPGAGFSVSEEDKAVLHQ-ICPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL---VAQ 175
             ++++D   G  TDE KA   T I         G  H+ +++P LL  GL  L   VA+
Sbjct: 128 RGQTVQDRCYGMFTDEQKALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRTKVAR 187

Query: 176 MQQHCQQQP-----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            ++  Q        +  F +A  + L A  +HI RYA +A  MA   +   RR ELL IA
Sbjct: 188 RRERLQLTDWSDLHKEQFLKAIDISLVALSEHIERYAAVARQMAQEESRDWRRTELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQTFWQA QL +++ ++LQ ESN  S+S GR DQY+ P+Y+    L    
Sbjct: 248 ENCALIAHQPPQTFWQALQLCYFIQLMLQIESNGHSVSFGRLDQYLYPWYRRDVELENSL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
                 E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 SREQAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLVQGKAIDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A I   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAVLESCGRLKSTQPNLSVRYHAGISDDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHE--------------- 449
           V  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L +               
Sbjct: 428 VEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEQGRDATSGQVFLPQEQ 487

Query: 450 --NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKG 507
             ++GN    ++ ++ Q   +I +Y    +E   + D    + A   + S+ + DC+E+G
Sbjct: 488 GLSKGNFT-DFDQVMAQWDQQIRYYTRKSIEIECVVDTVLEENAHDIVCSALVDDCIERG 546

Query: 508 RDITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE 566
           + I  GGARY++ SG+Q +GIANL +SL A++ +VFEQQ +   +L + L  +FA   GE
Sbjct: 547 KSIKQGGARYDWVSGLQ-VGIANLGNSLAAVRKLVFEQQLIGQQQLATALSNDFAGLNGE 605

Query: 567 KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVS 620
           ++R  LIN   KYGND+D+VD +     + Y  E+++Y N      P GG +  G+ ++S
Sbjct: 606 QLRQHLINSAPKYGNDVDDVDQLLVRAYQTYIDELKQYHNTRFGRGPIGGTYYAGTSSIS 665

Query: 621 AHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLN 680
           A+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  S+SKL    +  G LLN
Sbjct: 666 ANVPFGAATMATPDGRKAHSPLAEGA-SPASGTDHLGPTAVFNSLSKLPTASILGGVLLN 724

Query: 681 VKFTPATLEGEAGLRKLADFLRAFTQLKL-QHIQFNVVNADTLREAQQRPQDYAGLVVRV 739
            K  P+TL+      KL   LR F +  L  H+Q+N+V+ +TL +A+Q P  Y  LVVRV
Sbjct: 725 QKLNPSTLDNPRDREKLMMMLRTFFEEYLGWHVQYNIVSRETLVDAKQHPDRYRDLVVRV 784

Query: 740 AGYSAFFVELSKEIQDDIIRRTAHQL 765
           AGYSAFF  LS + QDDII RT H L
Sbjct: 785 AGYSAFFTALSPDAQDDIIARTEHTL 810



>ref|ZP_01258449.1| putative pyruvate formate lyase [Vibrio alginolyticus 12G01]
 gb|EAS78259.1| putative pyruvate formate lyase [Vibrio alginolyticus 12G01]
          Length = 812

 Score =  462 bits (1189), Expect = e-128
 Identities = 299/810 (36%), Positives = 445/810 (54%), Gaps = 48/810 (5%)

Query: 1   MTNRISRLKTALF-ANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           +  RI   K+AL    T  +  ERA  YT +++  E +PVI++RA A    L    I I+
Sbjct: 6   LPERIKAHKSALVNIVTPPVCTERAEAYTRAYQANEDKPVIVQRALALQEHLRTRTIWIK 65

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
            +ELI GN+  K RA  + PE    W+  E+D+   RP   FA++EEDK+     + PYW
Sbjct: 66  HDELIVGNQASKVRAAPIFPEYTVRWIEAEIDELADRPGAGFAVTEEDKQSIHS-ITPYW 124

Query: 120 EKRSMKDFINGQMTDEVKAA-TNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE +    +T I +      G  H+ +D  ++L  G+  L+  ++Q
Sbjct: 125 RGKTVQDRCYGLFTDEQQEILASTIIKAEGNMTSGDAHLAVDNEKILKLGMNGLLEDVRQ 184

Query: 179 HCQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
           H             +  FY++  ++L A Q H++ YAELA  MA   T   R+ EL +IA
Sbjct: 185 HRANNDVSTFEGLKKEQFYKSVEIVLLAIQDHMVSYAELAAKMALEETRPLRKAELESIA 244

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-D 289
              RH A H P+ FWQA QL +++ ++LQ ESN  S+S GR DQ++  FY   +  G  +
Sbjct: 245 ANCRHVANHAPENFWQALQLSYFVQLMLQIESNGHSVSFGRMDQFLNEFYVRDIENGAIE 304

Query: 290 AAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG--LTENG--RSAVNVLS 345
             F  ELL+S W+K  ++  +RS + ++  AG P      +GG  L E G    AVN LS
Sbjct: 305 KDFALELLQSCWLKLLEVNKIRSGAHSKASAGSPLYQNVCIGGQKLNEKGEPEDAVNPLS 364

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +  ++  FLM   E I+ G G+P   NDE+V+P F+  G
Sbjct: 365 WAILESCGQLRSTQPNLSVRYHEGLNQEFLMGCIEVIKCGFGMPAFNNDEIVIPEFIKLG 424

Query: 406 VSLEDARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHE----NEGNAALTYEG 460
           V  EDA +Y+ +GC+E ++PG+  Y    ++  N  +++   L+E      G A L ++ 
Sbjct: 425 VEKEDAYNYASIGCIETAVPGKWGYRCTGMSFINFARILLASLNEGVDATTGKAFLPHDK 484

Query: 461 LL--------EQIRA----KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
            L        EQ+ A    +I +Y    +E   + D      A     S+ + DCL +G+
Sbjct: 485 SLAKGNFENFEQVTASWAEQIRYYTRKSIEIDTVVDSVLEQQAQDIFCSTLVDDCLARGK 544

Query: 509 DITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFE-----QQRLSFDELLSVLKANFAT 562
            + +GGA+Y++ SG+Q +GIANL +SL A+K +VF+     Q  +S  +L   L  +F  
Sbjct: 545 TVKEGGAKYDWVSGLQ-VGIANLGNSLAAIKHLVFDDAQITQPLISQQQLAKALAEDFDG 603

Query: 563 PEGEKVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGS 616
            E E++R RLIN   KYGND D VD + A+  + Y  E+E++ N      P GG +  G+
Sbjct: 604 MENEQLRQRLINFAPKYGNDDDAVDQLLADAYQVYIDELEQFVNTRHGRGPIGGGYYAGT 663

Query: 617 YTVSAHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNG 676
            ++SA+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  SV K+    +  G
Sbjct: 664 SSISANVPFGASTMATPDGRKAKMPLAEGA-SPSSGSDRLGPTAVYNSVGKIQANKILGG 722

Query: 677 TLLNVKFTPATLEGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGL 735
            LLN K +PA +E E    KL+  +R  F   K  H+Q+N+V+ +TL  A++ P+ Y  L
Sbjct: 723 VLLNQKLSPAAVESEGDKLKLSMLIRTFFNHHKGWHVQYNIVSRETLLAAKKNPEQYRDL 782

Query: 736 VVRVAGYSAFFVELSKEIQDDIIRRTAHQL 765
           VVRVAGYSAFF  LS + QDDII RT H+L
Sbjct: 783 VVRVAGYSAFFTALSPDAQDDIIARTEHEL 812



>ref|ZP_00831656.1| COG1882: Pyruvate-formate lyase [Yersinia frederiksenii ATCC 33641]
          Length = 810

 Score =  462 bits (1189), Expect = e-128
 Identities = 296/806 (36%), Positives = 441/806 (54%), Gaps = 45/806 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           ++ R  + K AL    +  +  ERA  YT +++Q + +P+ +RRA A A+ L+   + I+
Sbjct: 9   LSERTKQHKNALIHIVKPPVCTERAQHYTEAYQQHQDKPLPVRRALALAHHLQQRTVWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           ++ELI GN+  + RA  + PE    W+  E+D+   RP   F++SE+DK +  + + P+W
Sbjct: 69  NDELIIGNQASQLRAAPIFPEYTVSWIENEIDELADRPGAGFSVSEQDKAVLHQ-ICPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQ 178
             ++++D   G  TDE KA   T I         G  H+ +++P LL  GL  L A++  
Sbjct: 128 RGQTVQDRCYGMFTDEQKALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRAKVTH 187

Query: 179 HCQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
              +          +  F +A  + L A  +HI RYA +A  MAA  T   RR EL TIA
Sbjct: 188 RRSRLQLTDWSDLHKEQFLKAIDISLVALSEHIERYAAVARQMAAEETREWRRIELQTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDA 290
                 A   PQTFWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+  +      
Sbjct: 248 VNCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRLDQYLYPWYRRDVELENTL 307

Query: 291 AFLK--ELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           +  K  E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 SREKAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLVQGKAIDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A I   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAVLESCGRLRSTQPNLSVRYHAGISDDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHE--------------- 449
           V  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L +               
Sbjct: 428 VEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEQGRDATSGQVFLPQKQ 487

Query: 450 --NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKG 507
             ++GN A  +  ++ Q   +I +Y    +E   + D    + A   + S+ + DC+E+G
Sbjct: 488 GLSKGNFA-DFSQVMAQWDEQIRYYTRKSIEIECVVDTVLEENAHDIVCSALVDDCIERG 546

Query: 508 RDITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE 566
           + I  GGARY++ SG+Q +GIANL +SL A++ +VFEQQ +   +L + L  +FA   GE
Sbjct: 547 KSIKQGGARYDWVSGLQ-VGIANLGNSLAAVRKLVFEQQLIGQQQLATALANDFAGLNGE 605

Query: 567 KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVS 620
           ++R  LIN   KYGND+D+VD +     + Y  E+++Y N      P GG +  G+ ++S
Sbjct: 606 QLRQHLINSAPKYGNDVDDVDQLLVRAYQTYIDELKQYHNTRFGRGPIGGTYYAGTSSIS 665

Query: 621 AHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLN 680
           A+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  S+SKL    +  G LLN
Sbjct: 666 ANVPFGAATMATPDGRKAHSPLAEGA-SPASGTDHLGPTAVFNSLSKLPTASILGGVLLN 724

Query: 681 VKFTPATLEGEAGLRKLADFLRAFTQLKL-QHIQFNVVNADTLREAQQRPQDYAGLVVRV 739
            K  P+TL+      KL   LR F +  L  H+Q+N+V+ +TL +A+Q P  Y  LVVRV
Sbjct: 725 QKLNPSTLDNPRDREKLMMMLRTFFEEYLGWHVQYNIVSRETLLDAKQHPDRYRDLVVRV 784

Query: 740 AGYSAFFVELSKEIQDDIIRRTAHQL 765
           AGYSAFF  LS + QDDII RT H L
Sbjct: 785 AGYSAFFTALSPDAQDDIIARTEHTL 810



>ref|ZP_00823788.1| COG1882: Pyruvate-formate lyase [Yersinia bercovieri ATCC 43970]
          Length = 810

 Score =  461 bits (1187), Expect = e-128
 Identities = 300/806 (37%), Positives = 440/806 (54%), Gaps = 45/806 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           ++ R  + K AL    +  +  ERAL YT +++Q + +P+ +RRA A A+ L+   + I+
Sbjct: 9   LSERTKQHKNALIHIVKPPVCTERALHYTEAYQQHQDKPLPVRRALALAHHLQQRTVWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           ++ELI GN+  + RA  + PE    W+  E+DQ   RP   F++SE DK +  + L P+W
Sbjct: 69  NDELIIGNQASQLRAAPIFPEYTVGWIESEIDQLADRPGAGFSVSEADKAVLHQ-LCPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL---VAQ 175
             ++++D   G  TDE KA   T I         G  H+ +++P LL  GL  L   VA 
Sbjct: 128 RGQTVQDRCYGMFTDEQKALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRTKVAS 187

Query: 176 MQQHCQQQP-----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            +   Q        +  F +A  + L A  +HI RY  +A+ MA   T   RR ELL IA
Sbjct: 188 RRARLQLTDWSDLHKEQFLKAIDISLVALSEHIERYGAVAQQMAEIETRDWRRAELLAIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGE 288
           E     A   PQ+FWQA QL +++ +ILQ ESN  S+S GR DQY+ P+Y+    L    
Sbjct: 248 ENCALIAHQPPQSFWQALQLCYFIQLILQIESNGHSVSFGRLDQYLYPWYRRDVELENSL 307

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT-ENGRS--AVNVLS 345
                 E+L S W+K  ++  +RS S ++  AG P      +GG     GR+  AVN LS
Sbjct: 308 SREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLVQGRAIDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A I   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAVLESCGRLKSTQPNLSVRYHAGISDDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHE--------------- 449
           V  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L +               
Sbjct: 428 VEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEQGRDATSGQVFLPQEQ 487

Query: 450 --NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKG 507
             ++GN    +  ++ Q   +I +Y    +E   + D    + A   + S+ + DC+E+G
Sbjct: 488 GLSQGNFT-DFAQVMAQWDQQIRYYTRKSIEIECVVDTVLEENAHDIVCSALVDDCIERG 546

Query: 508 RDITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE 566
           + I  GGARY++ SG+Q +GIANL +SL A++ +VFEQQ +   +L + L  +FA   GE
Sbjct: 547 KSIKQGGARYDWVSGLQ-VGIANLGNSLAAVRKLVFEQQLIGQQQLATALTNDFAGLNGE 605

Query: 567 KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVS 620
           ++R  LIN   KYGND+D+VD +     + Y  E+++Y N      P GG +  G+ ++S
Sbjct: 606 QLRQHLINSAPKYGNDVDDVDQLLVRAYQTYIDELKQYHNTRFGRGPIGGTYYAGTSSIS 665

Query: 621 AHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLN 680
           A+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  S+SKL    +  G LLN
Sbjct: 666 ANVPFGAATMATPDGRKAHSPLAEGA-SPASGTDHLGPTAVFNSLSKLPTASILGGVLLN 724

Query: 681 VKFTPATLEGEAGLRKLADFLRAFTQLKL-QHIQFNVVNADTLREAQQRPQDYAGLVVRV 739
            K  P+TL+      KL   LR F +  L  H+Q+N+V+ +TL +A+Q P  Y  LVVRV
Sbjct: 725 QKLNPSTLDNPRDREKLMMMLRTFFEEYLGWHVQYNIVSRETLVDAKQHPDRYRDLVVRV 784

Query: 740 AGYSAFFVELSKEIQDDIIRRTAHQL 765
           AGYSAFF  LS + QDDII RT H L
Sbjct: 785 AGYSAFFTALSPDAQDDIIARTEHTL 810



>ref|ZP_01534560.1| pyruvate formate-lyase [Serratia proteamaculans 568]
 gb|EAV32944.1| pyruvate formate-lyase [Serratia proteamaculans 568]
          Length = 810

 Score =  460 bits (1184), Expect = e-127
 Identities = 296/787 (37%), Positives = 430/787 (54%), Gaps = 44/787 (5%)

Query: 19  ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAGIMS 78
           +  ERA  YT +++Q   +P+ +RRA A A  L    + I ++ELI GN+  + RA  + 
Sbjct: 28  VCTERAQHYTEAYQQHLDKPLPVRRALALANHLAKRTLRIDNDELIIGNQASELRAAPIF 87

Query: 79  PEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKA 138
           PE    W+  E+DQ   RP   F+ISEE+K I    + P+W  ++++D   G  TDE +A
Sbjct: 88  PEYTVSWIEDEIDQLADRPGAGFSISEENKAILHR-ICPWWRGQTVQDRCYGMFTDEQRA 146

Query: 139 ATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH--------CQQQPENHFY 189
              T I         G  H+ +++P LL  GL  L  ++ +          Q+  +  F 
Sbjct: 147 LLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRDKVDERRSRIHLTDWQELQQEQFL 206

Query: 190 QAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQACQ 249
           +A  L LEA   HILR+AELA +MA   +   R EEL  IAE     A   PQTFWQA Q
Sbjct: 207 KAIDLTLEALSAHILRFAELARSMAQAESRHWRSEELQAIAENCELIAHRPPQTFWQALQ 266

Query: 250 LFWYMNIILQYESNASSLSLGRFDQYMLPFYQ--TSLTQGEDAAFLKELLESLWVKCNDI 307
           L +++ + LQ ESN  S+S GR DQY+ P+Y+    L Q        E+L S W+K  +I
Sbjct: 267 LCYFIQLTLQIESNGHSVSFGRLDQYLYPWYRRDVELEQTLPRERAIEMLHSCWLKLLEI 326

Query: 308 VLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLSFLCLDAYQSVQLPQPNLGV 364
             +RS S ++  AG P      +GG   +  + R AVN LS+  L++   ++  QPNL V
Sbjct: 327 NKIRSGSHSKASAGSPLYQNVTIGGQQLVDGSPRDAVNPLSYTILESCGRLRSTQPNLSV 386

Query: 365 RTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELSI 424
           R +A + + FL    + IR G G+P   NDE+V+P F+  GV  +DA DY+ +GC+E ++
Sbjct: 387 RYHAGMSSDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGVEPQDAYDYAAIGCIETAV 446

Query: 425 PGRT-YGLHDIAMFNLLKVMEICLHE-----------------NEGNAALTYEGLLEQIR 466
            G+  Y    ++  N  +V+   L +                 + GN +  ++ +L    
Sbjct: 447 GGKWGYRCTGMSFINFARVLLAALEQGRDATSGKVFLPQELALSRGNFS-HFDQVLGAWD 505

Query: 467 AKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNF-SGVQGI 525
           ++I +Y    +E   + D    + A   L S+ + DC+E+G+ I  GGA+Y++ SG+Q +
Sbjct: 506 SQIRYYTRKSIEIECVVDSVLEENAHDILCSALVDDCIERGKSIKQGGAKYDWVSGLQ-V 564

Query: 526 GIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDE 585
           GIANL +SL A++ +VFEQ  +   +L + L  +F    GE++R RL+N   KYGND+DE
Sbjct: 565 GIANLGNSLAAVRKLVFEQGAIGQQQLAAALANDFDGLSGEQLRQRLLNAAPKYGNDVDE 624

Query: 586 VDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAG 639
           VD +     + Y  E+ +Y N      P GG +  G+ ++SA+VP G+   ATPDGR A 
Sbjct: 625 VDQLLVRAYQSYIDELAQYHNTRFGRGPIGGTYYAGTSSISANVPFGAATLATPDGRKAH 684

Query: 640 EQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLAD 699
             LA+G  SP  G D  GPTAV  S+SKL    +  G LLN K  PATLE      KL  
Sbjct: 685 TPLAEGA-SPASGTDHLGPTAVFNSLSKLPTAAILGGVLLNQKLNPATLENPVDREKLML 743

Query: 700 FLRAFTQLKL-QHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDII 758
            LR F +  L  H+Q+N+V+ +TL EA+Q P  Y  LVVRVAGYSAFF  LS + QDDII
Sbjct: 744 MLRTFFETYLGWHVQYNIVSRETLLEAKQHPDQYRDLVVRVAGYSAFFTALSPDAQDDII 803

Query: 759 RRTAHQL 765
            RT H +
Sbjct: 804 ARTEHTI 810



>ref|ZP_01149311.1| Pyruvate formate-lyase [Desulfotomaculum reducens MI-1]
 gb|EAR43258.1| Pyruvate formate-lyase [Desulfotomaculum reducens MI-1]
          Length = 785

 Score =  460 bits (1184), Expect = e-127
 Identities = 283/792 (35%), Positives = 435/792 (54%), Gaps = 39/792 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           M  R++ LK         +S ERA L T  ++        ++RA A  Y++EH  I I D
Sbjct: 1   MKERVAALKQQSLETPPWLSTERAQLLTGFYKNAGDTSTPVKRALAFQYLMEHKTICIND 60

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
            ELI G R   P+A    PE+  +  +++L     R +  F +S++ K +YREE+ P+W+
Sbjct: 61  GELIVGERGPAPQASPTYPELCCH-SMQDLQILNDREKIPFLVSDQAKEVYREEIIPFWQ 119

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
            +SM+D I  +M++E K A    IF+     +  GH ++D  ++   G  +   ++ +  
Sbjct: 120 GKSMRDKIFQEMSEEWKQAYEHGIFTEFMEQRAPGHTVLD-DKIYRKGFLDFQREIAESL 178

Query: 181 QQ-----QPENHFYQAALLLLEASQKHILRYA----ELAETMAANCTDAQRREELLTIAE 231
           Q+      P+ ++ Q  L  +      I+R+A    E A  +A+   +A RR EL  IAE
Sbjct: 179 QKLDYYNDPKAYYKQEQLKAMRICADAIIRFAQRHAEKARELASQERNAGRRAELERIAE 238

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNA-SSLSLGRFDQYMLPFYQTSLTQG--- 287
           +  H     P+ FW+A Q +W++++ +  E N   + + GR DQ++ PFYQ  + +G   
Sbjct: 239 VCTHVPAQAPRDFWEALQSYWFVHLGVITELNTWDAFNPGRLDQHLNPFYQRGIREGTLT 298

Query: 288 EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTAL-LGGLTENGRSAVNVLSF 346
           +D A  KELL+  WVK N+             +G  T +  +  GGL  +G   VN +S+
Sbjct: 299 KDQA--KELLQCFWVKFNNQPAPPKVGVTAEESGTYTDFANINSGGLKRDGSDGVNEVSY 356

Query: 347 LCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGV 406
           L LD    ++L QP+  ++ +      FL +  + IR G G P IFN + ++   L +G 
Sbjct: 357 LVLDVIDEMRLLQPSSNIQLSKKNPDRFLKRACQIIRKGWGQPSIFNADAIIEELLRQGK 416

Query: 407 SLEDARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEG------------- 452
           ++EDAR     GCVE    G+ +Y L      NL+K++E+ L+  +              
Sbjct: 417 TIEDARAGGASGCVETGAFGKESYIL--TGYLNLVKILELVLNNGQDPRTGRQLGPATGD 474

Query: 453 -NAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDIT 511
                ++  LLE  + ++++++ + V+G+NI +  +  + P P LS  I DC+ KG+D  
Sbjct: 475 PTGFNSFGQLLEAFQQQLNYFVNIKVKGNNIIERLYATYMPAPFLSILIDDCIAKGQDYN 534

Query: 512 DGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRAR 571
           DGGARYN + +QG+G+ +L+D L ALK  +FEQ   +  +LL  L  NFA  E  KVR  
Sbjct: 535 DGGARYNTTYIQGVGLGSLTDCLSALKYHIFEQGTFTMPQLLEALNLNFAGQE--KVRQV 592

Query: 572 LINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGA 631
           L+N+  KYGND D  D I   +   + +EV    N +GG +       + HV  GSV+GA
Sbjct: 593 LLNKTPKYGNDDDFADEIMTTIFDIFYQEVNGRSNTKGGVYRINLLPTTCHVYFGSVIGA 652

Query: 632 TPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGE 691
           TPDGR A + L++G +SP+ G D QGPTAV+KS +K+D+ + + GTLLN KF P+ L G+
Sbjct: 653 TPDGRRAWQPLSEG-ISPVQGADRQGPTAVIKSAAKMDH-IRTGGTLLNQKFAPSVLAGD 710

Query: 692 AGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSK 751
            GL KL   +RA+ +L   HIQFNVV+A  LREAQ+ P+ Y  L+VRVAGYS +F  LSK
Sbjct: 711 EGLNKLTHLVRAYFKLDGHHIQFNVVDAKILREAQRNPEQYRDLIVRVAGYSDYFCNLSK 770

Query: 752 EIQDDIIRRTAH 763
            +QD+II RT H
Sbjct: 771 ALQDEIIARTEH 782



>ref|NP_720932.1| formate acetyltransferase (pyruvate formate-lyase 2) [Streptococcus
           mutans UA159]
 gb|AAN58238.1|AE014895_3 formate acetyltransferase (pyruvate formate-lyase 2) [Streptococcus
           mutans UA159]
          Length = 818

 Score =  460 bits (1183), Expect = e-127
 Identities = 294/798 (36%), Positives = 432/798 (54%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+   +  +      I  ERA+L T ++++ + +P +L+RA     ILE + + I D
Sbjct: 25  LTERMYSYRDKVLDKKPYIDAERAILATEAYKEHQEKPNVLKRAYMLKNILEKMSLYIDD 84

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +I GN+    +   + PE    ++L ELD F  R  D F I+EE K+  R+ + P+WE
Sbjct: 85  ETMIVGNQASSDKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKKQIRD-IAPFWE 143

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             +++      + DEV+    T  F +  + + G  H+ ++Y +LL  GL     + ++ 
Sbjct: 144 NNNLRARAGAMLPDEVQVYMETGFFGMEGKMNSGDAHLAVNYQKLLELGLVGFEERTREA 203

Query: 180 CQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
                        + HFY + L+ ++A + +  R+  LA+ MA     A+RR ELL IA 
Sbjct: 204 KADLDLTDPASIDKYHFYDSILVTIDAVKTYAQRFVTLAKEMAETAA-AKRRRELLEIAA 262

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I      +  +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G +  
Sbjct: 263 ICERVPYYPARTFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVKADLEAGRETE 322

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS +     AG P      +GG T   + AVN LSFL L 
Sbjct: 323 DSIVERLTNLWIKTLTINKVRSQAHTFSSAGSPLYQNVTVGGQTRAKKDAVNPLSFLVLK 382

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A ++  F+ +  E ++ G G+P   NDE+++P+F+ +GV+ ED
Sbjct: 383 SVAQTHLPQPNLTVRYHAGLNPDFMNEAIEVMKLGFGMPAFNNDEIIIPSFIAKGVAEED 442

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  K++ I ++     A+              
Sbjct: 443 AYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKILLITMNNGIDPASGKRFAPEFGHFVDM 502

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            +YE L       I +   + V   N  D+      P  L S+   DC+ +G+ + +GGA
Sbjct: 503 TSYEDLKSAWDKTIRYLTRMSVIVENAIDLSLEREVPDILCSALTDDCIGRGKHLKEGGA 562

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL A+K +VFE++RL+  EL   L++++A   G ++R  LIN
Sbjct: 563 VYDYISGLQ-VGIANLSDSLAAVKKLVFEEKRLTTAELWEALQSDYAGEHGGEIRQMLIN 621

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D +  +    Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 622 DAPKYGNDNDYADQLVCDCYDVYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 681

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D  GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 682 TLATPDGRHAGAPLAE-GCSPSHNMDKNGPTSVLKSVSKLPTAEIVGGVLLNQKVNPQTL 740

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E   +KL   LRA F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 741 SKEEDKQKLIALLRAFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 800

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 801 VLSKATQDDIIARTEHAL 818



>ref|ZP_00874721.1| Pyruvate formate-lyase [Streptococcus suis 89/1591]
 gb|EAP41130.1| Pyruvate formate-lyase [Streptococcus suis 89/1591]
          Length = 814

 Score =  455 bits (1171), Expect = e-126
 Identities = 292/798 (36%), Positives = 431/798 (54%), Gaps = 36/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T+R+++ +  +      I  ERA+L T ++++   +P +L+RA     ILE++ + I +
Sbjct: 20  LTDRMNKYREDVLDKKPYIDAERAVLATKAYQEHREKPNVLKRAYMLKEILENMTLYIEE 79

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E LIAGN+    +   + PE    ++L ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 80  ESLIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKEQLRS-IAPFWE 138

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLG---ELVAQM 176
           K +++      + +EV+    T  F +  + + G  H+ ++Y ++L  GL    E V   
Sbjct: 139 KNNLRSRAGVLLPEEVQVYMETGFFGMEGKMNSGDAHLAVNYQKVLEQGLRGFEERVRAA 198

Query: 177 QQHCQQQP-----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
           + +          + HFY +  ++++A + +  R+  LA  +A     AQRR+ELL IA 
Sbjct: 199 KANLDLTDPASIDKYHFYDSIFIIIDAVKAYANRFVALATELAEKAPTAQRRQELLEIAR 258

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I         +TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+    L  G +  
Sbjct: 259 ICAKVPYEPAETFAEAVQSVWFIQCILQIESNGHSLSYGRFDQYMYPYVNADLEAGRETE 318

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS S     AG P      +GG T + + AVN LS+L L 
Sbjct: 319 DSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLK 378

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GV  ED
Sbjct: 379 SVAQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIEKGVLEED 438

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------- 455
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I +++    A+              
Sbjct: 439 AYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPAFGHFKDM 498

Query: 456 LTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
            ++E L       + H   + V   N  DI      P  L S+   DC+ +G+ + +GGA
Sbjct: 499 KSFEELETAWEKTLRHLTRMSVIVENAIDIALEREVPDILCSALTDDCIGRGKHLKEGGA 558

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL A+K +VFE+ RL+ +EL   L+ ++A   G++++  LI 
Sbjct: 559 IYDYISGLQ-VGIANLSDSLAAIKKLVFEEGRLTPEELWHALETDYAGERGKEIQEMLIE 617

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D +       Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 618 DAPKYGNDDDYADQLVTAAYDIYIDEIAKYPNTRFGRGPIGGIRYSGTSSISANVGQGRG 677

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D  GPT+VLKSV+KL    +  G LLN K  P TL
Sbjct: 678 TLATPDGRNAGTPLAE-GCSPSHNMDKNGPTSVLKSVAKLPTHEIVGGVLLNQKVNPQTL 736

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E   +KL   LR  F +L   HIQ+NVV+ +TL +AQ  P+ +  L+VRVAGYSAFF 
Sbjct: 737 AKEEDKQKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQLHPEKHRDLIVRVAGYSAFFN 796

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LS+  QDDII RT H L
Sbjct: 797 VLSRATQDDIIGRTEHTL 814



>ref|YP_857360.1| pyruvate formate-lyase [Aeromonas hydrophila subsp. hydrophila ATCC
           7966]
 gb|ABK39354.1| pyruvate formate-lyase [Aeromonas hydrophila subsp. hydrophila ATCC
           7966]
          Length = 810

 Score =  453 bits (1166), Expect = e-125
 Identities = 293/788 (37%), Positives = 427/788 (54%), Gaps = 46/788 (5%)

Query: 19  ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAGIMS 78
           +  ERA  YT +++     P+ +RRA A A  L+   I I+ +ELI GN+  + RA  + 
Sbjct: 28  VCTERARHYTQAYQAHLARPLPVRRALALALHLKERTIWIKHDELIVGNQASQVRAAPLF 87

Query: 79  PEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKA 138
           PE    W+ KE+D+   RP   FA+SE DK +    L P+W  ++++D   G  TDE K 
Sbjct: 88  PEYTVGWIEKEIDELADRPGAGFAVSEADK-LAIHALTPFWNGQTVQDRCYGLFTDEQKG 146

Query: 139 ATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQQP--------ENHFY 189
              + I         G  H+ ++Y +LL  GL  L A++ + C +             F 
Sbjct: 147 LLESGIIKAEGNMTSGDAHLAVNYEQLLALGLDGLKAKVAERCGRLDLADWADLQREQFL 206

Query: 190 QAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQACQ 249
           QA  +  +A  +HI RYA LA  +A      +RR EL TIA    H A   P+TFWQA Q
Sbjct: 207 QAVAITFDAVSQHIERYAALARELAQQEPRPERRCELETIALNCAHIAHRPPETFWQALQ 266

Query: 250 LFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAAFLK--ELLESLWVKCNDI 307
           L +++ +ILQ ESN  S+S GR DQY+ P+Y+  +   E     +  ELL+  W+K  ++
Sbjct: 267 LCYFIQLILQIESNGHSVSFGRMDQYLYPWYRREVELSESLPRTRAIELLQGCWLKLLEV 326

Query: 308 VLLRSTSSARYFAGFPTGYTALLGGLT-ENGRS--AVNVLSFLCLDAYQSVQLPQPNLGV 364
             +RS + ++  AG P      +GG    +G++  AVN LS+  L++   ++  QPNL V
Sbjct: 327 NKIRSGTHSKASAGSPLYQNVTIGGQNWRDGKAHDAVNGLSYAILESCGQLRSTQPNLSV 386

Query: 365 RTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELSI 424
           R +A +   FL    + IR G G+P   NDEVV+P F+  GVS EDA  Y+ +GC+E ++
Sbjct: 387 RYHAGMSEDFLDACIQVIRCGFGMPAFNNDEVVIPEFIKLGVSEEDAHHYAAIGCIETAV 446

Query: 425 PGRT-YGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRA---------------- 467
           PG+  Y    ++  N  +++   L  + G  A T +  L Q ++                
Sbjct: 447 PGKWGYRCTGMSFINFARILLAAL--DGGRDATTGKVFLPQPQSLRQGTFGHFDEVMARW 504

Query: 468 --KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNF-SGVQG 524
             ++ ++    +E   + D      A   L S+ + DC+E+G+ I  GGA Y++ SG+Q 
Sbjct: 505 DEQVRYFTRKSIEIDCVVDSVLEAQAHDILCSALVDDCIERGKTIKQGGAVYDWVSGLQ- 563

Query: 525 IGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDID 584
           +GIANL +SL ALK +VFEQ  +   EL   L+ +FA  EGE++R RL +   KYGND+D
Sbjct: 564 VGIANLGNSLAALKKLVFEQGVVDQRELAEALEQDFAGLEGEQLRQRLTHAAPKYGNDLD 623

Query: 585 EVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSVVGATPDGRFA 638
           EVD +  +  + Y  E++   N      P GG +  G+ ++SA+VP G+   ATPDGR A
Sbjct: 624 EVDLLLVQAYQSYIDELKGLHNTRFGRGPIGGTYYAGTSSISANVPFGAATMATPDGRHA 683

Query: 639 GEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLA 698
              LA+G  SP  G D  GPTAV  S+ KL    +  G LLN K +PA+LE E    KL 
Sbjct: 684 RTPLAEGA-SPASGSDRLGPTAVFNSLGKLPTAAILGGVLLNQKLSPASLENERDKTKLM 742

Query: 699 DFLRAFTQL-KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDI 757
             LR F ++ K  H+Q+N+V+ +TL  A+  P  Y  LVVRVAGYSAFF  LS + QDDI
Sbjct: 743 SLLRTFFEVHKGWHVQYNIVSRETLLAAKAHPDQYRDLVVRVAGYSAFFTALSPDAQDDI 802

Query: 758 IRRTAHQL 765
           I RT H L
Sbjct: 803 IARTEHSL 810



>ref|ZP_00833020.1| COG1882: Pyruvate-formate lyase [Yersinia intermedia ATCC 29909]
          Length = 810

 Score =  452 bits (1163), Expect = e-125
 Identities = 293/806 (36%), Positives = 437/806 (54%), Gaps = 45/806 (5%)

Query: 1   MTNRISRLKTALFANTRE-ISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIR 59
           ++ R  + K AL    +  +  ERA  YT +++Q + +P+ +RRA A A+ L+   + I+
Sbjct: 9   LSERTKQHKNALIHIVKPPVCTERAQHYTEAYQQHQDKPLPVRRALALAHHLQLRTVWIK 68

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           ++ELI GN+  + RA  + PE    W+  E+D+   RP   F++S  DK +    + P+W
Sbjct: 69  NDELIIGNQASQLRAAPIFPEYTVSWIENEIDELADRPGAGFSVSAADKAVLHS-ICPWW 127

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL---VAQ 175
             ++++D   G  TDE KA   T I         G  H+ +++P LL  GL  L   VA 
Sbjct: 128 RGQTVQDRCYGMFTDEQKALLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLRSKVAS 187

Query: 176 MQQHCQQQP-----ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            ++  Q        +  F +A  + L A  +HI RYA +A  MA   +   RR EL TIA
Sbjct: 188 RRERLQLTDWSDLHKEQFLKAIDISLVALSEHIERYAAVARQMAEEESRDWRRIELHTIA 247

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDA 290
                 A   PQTFWQA QL +++ ++LQ ESN  S+S GR DQY+ P+Y+  +      
Sbjct: 248 TNCELIAHQPPQTFWQALQLCYFIQLMLQIESNGHSVSFGRLDQYLYPWYRRDVELENTL 307

Query: 291 AFLK--ELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGG---LTENGRSAVNVLS 345
           +  K  E+L S W+K  ++  +RS S ++  AG P      +GG   +      AVN LS
Sbjct: 308 SREKAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQKLVQGKAIDAVNPLS 367

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +  L++   ++  QPNL VR +A I   FL    + IR G G+P   NDE+V+P F+  G
Sbjct: 368 YAVLESCGRLRSTQPNLSVRYHAGISDDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLG 427

Query: 406 VSLEDARDYSVVGCVELSIPGRT-YGLHDIAMFNLLKVMEICLHE--------------- 449
           V  +DA DY+ +GC+E ++ G+  Y    ++  N  +VM   L +               
Sbjct: 428 VEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEQGKDATSGQVFLPQEQ 487

Query: 450 --NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKG 507
             ++GN    +  ++ Q   +I +Y    +E   + D    + A   + S+ + DC+E+G
Sbjct: 488 GLSQGNFT-DFSQVMAQWDQQIRYYTRKSIEIECVVDTVLEENAHDIVCSALVDDCIERG 546

Query: 508 RDITDGGARYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE 566
           + I  GGARY++ SG+Q +GIANL +SL A++ +VFEQQ +   +L + L  +FA   GE
Sbjct: 547 KSIKQGGARYDWVSGLQ-VGIANLGNSLAAVRKLVFEQQLIGQQQLATALANDFAGLNGE 605

Query: 567 KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVS 620
           ++R  L+N   KYGNDID+VD +     + Y  E+++Y N      P GG +  G+ ++S
Sbjct: 606 QLRQHLVNSAPKYGNDIDDVDQLLVRAYQTYIDELKQYHNTRFGRGPIGGTYYAGTSSIS 665

Query: 621 AHVPLGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLN 680
           A+VP G+   ATPDGR A   LA+G  SP  G D  GPTAV  S+SKL    +  G LLN
Sbjct: 666 ANVPFGAATMATPDGRKAHSPLAEGA-SPASGTDHLGPTAVFNSLSKLPTASILGGVLLN 724

Query: 681 VKFTPATLEGEAGLRKLADFLRAFTQLKL-QHIQFNVVNADTLREAQQRPQDYAGLVVRV 739
            K  P+TL+      KL   LR F +  L  H+Q+N+V+ +TL +A+Q P  Y  LVVRV
Sbjct: 725 QKLNPSTLDNPRDREKLMMMLRTFFEEYLGWHVQYNIVSRETLLDAKQHPDRYRDLVVRV 784

Query: 740 AGYSAFFVELSKEIQDDIIRRTAHQL 765
           AGYSAFF  LS + QDDII RT H L
Sbjct: 785 AGYSAFFTALSPDAQDDIIARTEHTL 810



>ref|YP_815753.1| pyruvate formate-lyase [Streptococcus pneumoniae D39]
 gb|ABJ53873.1| pyruvate formate-lyase [Streptococcus pneumoniae D39]
          Length = 812

 Score =  450 bits (1158), Expect = e-124
 Identities = 293/798 (36%), Positives = 433/798 (54%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+++ +  +      I  ERA+L T ++ + + +P +L+RA     ILE++ I I +
Sbjct: 19  LTERMNKYREDVLNKKPYIDAERAVLATRAYERYKEQPNVLKRAYMLKEILENMSIYIEE 78

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +IAGN+    +   + PE    ++L ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 79  ESMIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKEQLRS-IAPFWE 137

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL------- 172
             +++      + +EV     T  F +  + + G  H+ ++Y +LL  GL          
Sbjct: 138 NNNLRARAGALLPEEVSVYMETGFFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKA 197

Query: 173 -VAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
            VA          + HFY +  ++++A + +  R+  LA+++A N  + +R++ELL IA+
Sbjct: 198 KVALDLTDPASIDKYHFYDSIFIVIDAIKVYAKRFVALAKSLAENA-NPKRKKELLEIAD 256

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I          TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G++  
Sbjct: 257 ICSRVPYEPATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETE 316

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS S     AG P      +GG T + + AVN LS+L L 
Sbjct: 317 DSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLK 376

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GV  +D
Sbjct: 377 SVAQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDD 436

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I +++    A+             +
Sbjct: 437 AYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDM 496

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
                LE    K   Y+T M V   N  D+      P  L S+   DC+ +G+ + +GGA
Sbjct: 497 KNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGA 556

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL A+K +VFE++R+S  +L   L+ ++A  EG+ ++  LI+
Sbjct: 557 VYDYISGLQ-VGIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIH 615

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D +       Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 616 DAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 675

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D  GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 676 TLATPDGRNAGTPLAE-GCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 734

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 735 AKEEDKLKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 794

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 795 VLSKATQDDIIGRTEHTL 812



>ref|NP_357826.1| Formate acetyltransferase 3 [Streptococcus pneumoniae R6]
 gb|AAK99036.1| Formate acetyltransferase 3 [Streptococcus pneumoniae R6]
          Length = 815

 Score =  450 bits (1158), Expect = e-124
 Identities = 293/798 (36%), Positives = 433/798 (54%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+++ +  +      I  ERA+L T ++ + + +P +L+RA     ILE++ I I +
Sbjct: 22  LTERMNKYREDVLNKKPYIDAERAVLATRAYERYKEQPNVLKRAYMLKEILENMSIYIEE 81

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +IAGN+    +   + PE    ++L ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 82  ESMIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKEQLRS-IAPFWE 140

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL------- 172
             +++      + +EV     T  F +  + + G  H+ ++Y +LL  GL          
Sbjct: 141 NNNLRARAGALLPEEVSVYMETGFFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKA 200

Query: 173 -VAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
            VA          + HFY +  ++++A + +  R+  LA+++A N  + +R++ELL IA+
Sbjct: 201 KVALDLTDPASIDKYHFYDSIFIVIDAIKVYAKRFVALAKSLAENA-NPKRKKELLEIAD 259

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I          TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G++  
Sbjct: 260 ICSRVPYEPATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETE 319

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS S     AG P      +GG T + + AVN LS+L L 
Sbjct: 320 DSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLK 379

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GV  +D
Sbjct: 380 SVAQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDD 439

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I +++    A+             +
Sbjct: 440 AYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDM 499

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
                LE    K   Y+T M V   N  D+      P  L S+   DC+ +G+ + +GGA
Sbjct: 500 KNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGA 559

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL A+K +VFE++R+S  +L   L+ ++A  EG+ ++  LI+
Sbjct: 560 VYDYISGLQ-VGIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIH 618

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D +       Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 619 DAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 678

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D  GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 679 TLATPDGRNAGTPLAE-GCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 737

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 738 AKEEDKLKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 797

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 798 VLSKATQDDIIGRTEHTL 815



>ref|NP_344790.1| formate acetyltransferase, putative [Streptococcus pneumoniae
           TIGR4]
 ref|ZP_01409391.1| hypothetical protein SpneT_02000056 [Streptococcus pneumoniae
           TIGR4]
 gb|AAK74430.1| putative formate acetyltransferase [Streptococcus pneumoniae TIGR4]
          Length = 812

 Score =  450 bits (1157), Expect = e-124
 Identities = 293/798 (36%), Positives = 433/798 (54%), Gaps = 37/798 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+++ +  +      I  ERA+L T ++ + + +P +L+RA     ILE++ I I +
Sbjct: 19  LTERMNKYREDVLNKKPYIDAERAVLATRAYERYKEQPNVLKRAYMLKEILENMTIYIEE 78

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           E +IAGN+    +   + PE    ++L ELD F  R  D F I+EE K   R  + P+WE
Sbjct: 79  ESMIAGNQASSNKDAPIFPEYTLEFVLNELDLFEKRDGDVFYITEETKEQLRS-IAPFWE 137

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSIN-QTDKGQGHIIIDYPRLLNHGLGEL------- 172
             +++      + +EV     T  F +  + + G  H+ ++Y +LL  GL          
Sbjct: 138 NNNLRARAGALLPEEVSVYMETGFFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKA 197

Query: 173 -VAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAE 231
            VA          + HFY +  ++++A + +  R+  LA+++A N  + +R++ELL IA+
Sbjct: 198 KVALDLTDPASIDKYHFYDSIFIVIDAIKVYAKRFVALAKSLAENA-NPKRKKELLEIAD 256

Query: 232 ISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGEDAA 291
           I          TF +A Q  W++  ILQ ESN  SLS GRFDQYM P+ +  L  G++  
Sbjct: 257 ICSRVPYEPATTFAEAIQSVWFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETE 316

Query: 292 -FLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLD 350
             + E L +LW+K   I  +RS S     AG P      +GG T + + AVN LS+L L 
Sbjct: 317 DSIVERLTNLWIKTITINKVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLK 376

Query: 351 AYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLED 410
           +     LPQPNL VR +A +D  F+ +  E ++ G G+P   NDE+++P+F+ +GV  +D
Sbjct: 377 SVAQTHLPQPNLTVRYHAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDD 436

Query: 411 ARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHENEGNAA-------------L 456
           A DYS +GCVE ++PG+  Y    ++  N  KV+ I +++    A+             +
Sbjct: 437 AYDYSAIGCVETAVPGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGRFKDM 496

Query: 457 TYEGLLEQIRAKISHYITLM-VEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGA 515
                LE    K   Y+T M V   N  D+      P  L S+   DC+ +G+ + +GGA
Sbjct: 497 KNFSELENAWDKTLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGA 556

Query: 516 RYNF-SGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLIN 574
            Y++ SG+Q +GIANLSDSL A+K +VFE++R+S  +L   L+ ++A  EG+ ++  LI+
Sbjct: 557 VYDYISGLQ-VGIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIH 615

Query: 575 RFEKYGNDIDEVDNISAELLRHYCKEVEKYQN------PRGGYFTPGSYTVSAHVPLGSV 628
              KYGND D  D +       Y  E+ KY N      P GG    G+ ++SA+V  G  
Sbjct: 616 DAPKYGNDDDYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRG 675

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATPDGR AG  LA+ G SP    D  GPT+VLKSVSKL    +  G LLN K  P TL
Sbjct: 676 TLATPDGRNAGTPLAE-GCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTL 734

Query: 689 EGEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
             E    KL   LR  F +L   HIQ+NVV+ +TL +AQ+ P+ +  L+VRVAGYSAFF 
Sbjct: 735 AKEEDKLKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFN 794

Query: 748 ELSKEIQDDIIRRTAHQL 765
            LSK  QDDII RT H L
Sbjct: 795 VLSKATQDDIIGRTEHTL 812



>ref|ZP_00799753.1| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF]
 gb|EAO82242.1| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF]
          Length = 792

 Score =  440 bits (1132), Expect = e-121
 Identities = 276/777 (35%), Positives = 430/777 (55%), Gaps = 42/777 (5%)

Query: 19  ISLERALLYTASHRQTEG---EPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAG 75
           IS+ERA+L T ++ +  G   EP++  RA +  +++E+  I I D+ELI G R   P++ 
Sbjct: 25  ISIERAVLMTQAYEKYSGKVSEPML--RALSFKHLMENKTICINDDELIVGERGPTPQSA 82

Query: 76  IMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDE 135
              PE+  +  +++L+    R +  F ++ EDK+I RE++ PYW+ +S++DFI  +MT+E
Sbjct: 83  PTYPELCCH-TIEDLEMMNDREKISFTVTAEDKKIQREKIIPYWQGKSIRDFIFNEMTEE 141

Query: 136 VKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHCQQQP-----ENHFYQ 190
            K   +  IF+     +  GH + D  ++   G  +   ++ +  +        E +  Q
Sbjct: 142 WKDCYHGGIFTEFMEQRAPGHTVGD-DKIYKRGFLDFKLEIMEQLESLDYYNDIEAYEKQ 200

Query: 191 AALLLLEASQKHIL----RYAELAETMAANCTDAQRREELLTIAEISRHNAQHKPQTFWQ 246
             L  +E     I+    R+AE A+ +A N  + Q++ EL  IAE+        P  FW+
Sbjct: 201 EQLKAMEICADAIIIFAHRHAEKAKELAENEENPQKKRELEKIAEVCLRVPALPPGNFWE 260

Query: 247 ACQLFWYMNIILQYESNA-SSLSLGRFDQYMLPFYQTSLTQGE-DAAFLKELLESLWVKC 304
           A Q +W++++ +  E N   +   GR DQ++ PFYQ  +  G       KELLE  WVK 
Sbjct: 261 ALQSYWFVHLGVITELNTWDAFCPGRLDQHLHPFYQKGIEGGTLTPQGAKELLECFWVKF 320

Query: 305 NDIVLLRSTSSARYFAGFPTGYTAL-LGGLTENGRSAVNVLSFLCLDAYQSVQLPQPNLG 363
           N+             +G  T +  + +GGL  +G   VN +S+L L+    ++L QP+  
Sbjct: 321 NNQPAPPKVGITLQESGTYTDFANINIGGLKIDGSDGVNEVSYLLLEVIDEMKLLQPSSN 380

Query: 364 VRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLEDARDYSVVGCVELS 423
           ++ +      F+ K AE IR G G P +FN + VV   L +G S+EDAR     GCVE  
Sbjct: 381 IQVSKKNPDYFIKKAAEVIRKGWGQPSVFNADAVVEELLRQGKSIEDARCGGTSGCVETG 440

Query: 424 IPGRTYGLHDIAMFNLLKVMEICLHENEGNAALT----------------YEGLLEQIRA 467
             G+   +     FNL KV+EI L  N G   +T                ++ L E  + 
Sbjct: 441 AFGKESFILT-GYFNLTKVLEITL--NNGFDPVTGKKIGVQTEVVENLHSFKALFEAFKV 497

Query: 468 KISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGI 527
           +++H+I + ++G+NI +  +  + P P LS  I DC++  +D   GG RYN + +QG+GI
Sbjct: 498 QLNHFIDIKIKGNNIIEKLYAHYMPSPFLSILIDDCIKNAKDYNAGGTRYNTNYIQGVGI 557

Query: 528 ANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARLINRFEKYGNDIDEVD 587
           A+++DSL A+K  VF+ +  +  +L+  L  +F   E   +R  L+N+  +YGND D VD
Sbjct: 558 ASITDSLSAIKSHVFDDKLFTLRQLMETLHVDFKGHE--PIRQLLLNKTPRYGNDDDYVD 615

Query: 588 NISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGEQLADGGL 647
           +I  ++   + + V   +  RGG +       + HV  GSV+GATPDGR AG  L++G +
Sbjct: 616 SIMVKVFDAFYQAVNGRKTMRGGTYRINMLPTTCHVYFGSVIGATPDGRKAGRPLSEG-I 674

Query: 648 SPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQL 707
           SP+ G D +GPTAV+KS SK+D  L + GTLLN KFTP  LEGEAGL  +   +R++ +L
Sbjct: 675 SPVQGTDKKGPTAVIKSASKMDQ-LKTGGTLLNQKFTPNMLEGEAGLENVVHLVRSYFRL 733

Query: 708 KLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQ 764
              HIQFNVV+A TL++AQ  P+ Y  L+VRVAGYS +F  L+K +QD+II RT HQ
Sbjct: 734 DGHHIQFNVVDAATLKKAQANPEAYQNLIVRVAGYSDYFNNLNKGLQDEIIARTEHQ 790



>ref|ZP_01635825.1| hypothetical protein CdifQ_03001213 [Clostridium difficile
           QCD-32g58]
          Length = 790

 Score =  439 bits (1128), Expect = e-121
 Identities = 269/793 (33%), Positives = 425/793 (53%), Gaps = 40/793 (5%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           TNRI   +     +   I  ERA ++T SH++TEGE + +RRAKA     + + I I + 
Sbjct: 4   TNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIRRAKAFLETCKELPIKIFEN 63

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G      R GI++PE    W+ KE+D F  R QD + IS+E     R+E+FPYW+ 
Sbjct: 64  ELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDPYVISKEQIEFIRKEIFPYWKG 123

Query: 122 RSMKD-FINGQMTDEVKAATNTQIF-SINQTDKGQGHIIIDYPRLL--------NHGLGE 171
           +S+++ F+     D  K   +T I  + ++  +  G +  DY  +L             +
Sbjct: 124 KSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGEVTPDYQDILFVKGYKGIKEDADK 183

Query: 172 LVAQMQQHCQQQPEN-HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            + ++     +  E   FY++  ++ E       RY+ LA+ M+   TD +R+ EL+ I+
Sbjct: 184 KIKELDISVSENIEKIDFYKSVSIVAEGIMTLAQRYSNLAKEMSKQETDEKRKLELIKIS 243

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-D 289
           EI  +   + P  F++A Q  W++ +      N  +L+LGRFDQYM P+Y+    +G+  
Sbjct: 244 EICMNVPANPPTNFYEAIQFVWFVQLGGILSENPLALNLGRFDQYMYPYYENDAREGKIT 303

Query: 290 AAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCL 349
            +  +EL+E+LW+K ++ V   S ++A YFAG+       +GG   NG    N +S++CL
Sbjct: 304 ESEAQELIEALWIKLSEWVWTISANTANYFAGYNQFQNLTVGGKKRNGTDGTNDISYMCL 363

Query: 350 DAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLE 409
            A +SV+  QP L VR +      F+M  A+ ++ GTG P I +D       L  G   E
Sbjct: 364 KATESVKTHQPGLSVRVSQGAPDNFVMAVAKLVKQGTGFPAIHSDSAGAQMLLQDGYDAE 423

Query: 410 DARDYSVVGCVELSIPG--RTYGLHDIAMFNLLKVMEICLHENEGNAALT---------- 457
           DARD+S  GCV   +P   +T         N    +E  +  NEG + LT          
Sbjct: 424 DARDWSNCGCV---VPHFRKTGQWTSAVNINFAAALEYAM--NEGKSRLTGEKMGLDTKN 478

Query: 458 ------YEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDIT 511
                 +E L ++   ++++ +   V G+ +    H++  P P LS+ +  CL+KG D++
Sbjct: 479 ITEFTSFEELKDEFLKQLAYLVKSSVIGTTVAQQIHKEMVPRPFLSTCVDGCLDKGVDLS 538

Query: 512 DGGARYNFSGV-QGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRA 570
            GGA+YN   V  GIG+  +S+SL A+K +VFE +  + +EL   L  ++   EG +   
Sbjct: 539 KGGAKYNIGPVLTGIGLGVVSNSLAAIKKLVFEDKVTTLEELTKALNNDW---EGYEELR 595

Query: 571 RLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVG 630
           +L     KYGND D VD+++ E+   Y  E  KY++  G  F      +S +VP G +VG
Sbjct: 596 KLALDVPKYGNDNDYVDSLAIEVSDFYYTETRKYKDIFGSKFNSAFMGISNYVPTGKIVG 655

Query: 631 ATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEG 690
           ATP GR A + L +G +SP +G D   P A +KS SK+++ + + GTLLN++     +E 
Sbjct: 656 ATPCGRKATKPLTEG-VSPFVGTDTTSPLAAMKSASKINHDVHTGGTLLNLRLNQDLVET 714

Query: 691 EAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELS 750
           E GLR L   ++++  L   H+QFN ++ DTL +AQ+ P++Y  L+VRVAGYS  FV LS
Sbjct: 715 ERGLRNLTSMIKSYFALGGFHVQFNTISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLS 774

Query: 751 KEIQDDIIRRTAH 763
           +E+QD II R +H
Sbjct: 775 REMQDAIIARNSH 787



>emb|CAJ67970.1| glycerol dehydratase [Clostridium difficile 630]
          Length = 790

 Score =  437 bits (1125), Expect = e-121
 Identities = 268/793 (33%), Positives = 425/793 (53%), Gaps = 40/793 (5%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           TNRI   +     +   I  ERA ++T SH++TEGE + +RRAKA     + + I I + 
Sbjct: 4   TNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIRRAKAFLETCKELPIKIFEN 63

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G      R GI++PE    W+ KE+D F  R QD + IS+E     R+E+FPYW+ 
Sbjct: 64  ELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDPYVISKEQIEFIRKEIFPYWKG 123

Query: 122 RSMKD-FINGQMTDEVKAATNTQIF-SINQTDKGQGHIIIDYPRLL--------NHGLGE 171
           +S+++ F+     D  K   +T I  + ++  +  G +  DY  +L             +
Sbjct: 124 KSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGEVTPDYQDILFVKGYKGIKEDADK 183

Query: 172 LVAQMQQHCQQQPEN-HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
            + ++     +  E   FY++  ++ +       RY+ LA+ M+   TD +R+ EL+ I+
Sbjct: 184 KIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQRYSNLAKEMSKQETDEKRKLELIKIS 243

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE-D 289
           EI  +   + P  F++A Q  W++ +      N  +L+LGRFDQYM P+Y+    +G+  
Sbjct: 244 EICMNVPANPPTNFYEAIQFVWFVQLGGILSENPLALNLGRFDQYMYPYYENDAREGKIT 303

Query: 290 AAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCL 349
            +  +EL+E+LW+K ++ V   S ++A YFAG+       +GG   NG    N +S++CL
Sbjct: 304 ESEAQELIEALWIKLSEWVWTISANTANYFAGYNQFQNLTVGGKKRNGTDGTNDISYMCL 363

Query: 350 DAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVSLE 409
            A +SV+  QP L VR +      F+M  A+ ++ GTG P I +D       L  G   E
Sbjct: 364 KATESVKTHQPGLSVRVSQGAPDNFVMAVAKLVKQGTGFPAIHSDSAGAQMLLQDGYDAE 423

Query: 410 DARDYSVVGCVELSIPG--RTYGLHDIAMFNLLKVMEICLHENEGNAALT---------- 457
           DARD+S  GCV   +P   +T         N    +E  +  NEG + LT          
Sbjct: 424 DARDWSNCGCV---VPHFRKTGQWTSAVNINFAAALEYAM--NEGKSRLTGEKMGLDTKN 478

Query: 458 ------YEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDIT 511
                 +E L ++   ++++ +   V G+ +    H++  P P LS+ +  CL+KG D++
Sbjct: 479 ITEFTSFEELKDEFLKQLAYLVKSSVIGTTVAQQIHKEMVPRPFLSTCVDGCLDKGVDLS 538

Query: 512 DGGARYNFSGV-QGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRA 570
            GGA+YN   V  GIG+  +S+SL A+K +VFE +  + +EL   L  ++   EG +   
Sbjct: 539 KGGAKYNIGPVLTGIGLGVVSNSLAAIKKLVFEDKVTTLEELTKALNNDW---EGYEELR 595

Query: 571 RLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVG 630
           +L     KYGND D VD+++ E+   Y  E  KY++  G  F      +S +VP G +VG
Sbjct: 596 KLALDVPKYGNDNDYVDSLAIEVSDFYYTETRKYKDIFGSKFNSAFMGISNYVPTGKIVG 655

Query: 631 ATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEG 690
           ATP GR A + L +G +SP +G D   P A +KS SK+++ + + GTLLN++     +E 
Sbjct: 656 ATPCGRKATKPLTEG-VSPFVGTDTTSPLAAMKSASKINHDVHTGGTLLNLRLNQDLVET 714

Query: 691 EAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELS 750
           E GLR L   ++++  L   H+QFN ++ DTL +AQ+ P++Y  L+VRVAGYS  FV LS
Sbjct: 715 ERGLRNLTSMIKSYFALGGFHVQFNTISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLS 774

Query: 751 KEIQDDIIRRTAH 763
           +E+QD II R +H
Sbjct: 775 REMQDAIIARNSH 787



>ref|NP_953150.1| formate acetyltransferase [Geobacter sulfurreducens PCA]
 gb|AAR35477.1| formate acetyltransferase [Geobacter sulfurreducens PCA]
          Length = 786

 Score =  437 bits (1125), Expect = e-121
 Identities = 280/793 (35%), Positives = 424/793 (53%), Gaps = 40/793 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGE-PVILRRAKATAYILEHVEISIR 59
           MT R   L+         IS ERALL T  +R+ EG+  V + RA +  +I  H  I I 
Sbjct: 1   MTERTRELRRRSLEARPAISAERALLLTEFYRENEGKYSVPVMRALSFLHICRHKTIWIG 60

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           + EL+ G R  +P+A    PE+  +  L++L    +RP   +A+S E    Y E + PYW
Sbjct: 61  EGELVVGERGPEPKAVPTYPELTCH-SLEDLRILDSRPLTSYAVSAECLAAYEETVIPYW 119

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
             RS++D + G++  E   A    IF+     +  GH ++D  +    GL +  A + + 
Sbjct: 120 RGRSLRDKMFGELAPEWHEAYAAGIFTEFMEQRAPGHTVLD-EKPFRRGLLDFKADIARE 178

Query: 180 CQQQP---------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
             +           +    +A  +  +A+     R+A LA+ MAA  TD  R+ EL  IA
Sbjct: 179 IGRLDFVQDGAAWEKREQLRAMAISCDAAILFAERHAGLADEMAARETDPHRKRELERIA 238

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNA-SSLSLGRFDQYMLPFYQTSLTQGE- 288
           E+ RH   H P+ F +A Q +W+ ++ +  E N   ++S G  DQ++LPFY+  L  G  
Sbjct: 239 EVCRHVPAHAPRDFHEALQAYWFCHLAIITELNGWDAMSPGHLDQHLLPFYEQGLAHGSL 298

Query: 289 --DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTAL-LGGLTENGRSAVNVLS 345
             DAA  +ELLE  +VK N+             +G  T +  + LGGL  +G    N +S
Sbjct: 299 SRDAA--RELLECFFVKFNNHPAPPKVGVTAAESGTYTDFANINLGGLLPDGSDGSNEVS 356

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
            L LD    + L QP+  ++ +      FL      IR G G P IFN + VV   L +G
Sbjct: 357 HLLLDIIDEMHLLQPSSNIQLSRKSPDAFLSHALRVIRNGYGFPSIFNADSVVEEQLRQG 416

Query: 406 VSLEDARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHEN-------------- 450
            SL DAR     GCVE+   G+  Y L     FNL+K++E+ LH                
Sbjct: 417 KSLVDARAGGCSGCVEVGAFGKEAYIL--TGYFNLVKLLELALHNGVDPRTGRQLGPASG 474

Query: 451 EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDI 510
           + +   +++ L     A++ H+I + + G+ + +  +    P P LS  I DC+  GRD 
Sbjct: 475 DPSGFASFDDLYAAFEAQLRHFIEIKMAGNQLIEQIYCRLMPAPFLSVLIDDCIATGRDY 534

Query: 511 TDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRA 570
             GGARYN + +QG+GI +++DSL A+K +V++   ++  +L++ L A+FA  E   +R 
Sbjct: 535 NAGGARYNNTFIQGVGIGSITDSLSAIKALVYDSGHIALPDLVAALDADFAGQE--PLRQ 592

Query: 571 RLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVG 630
           RL+NR  KYGND D  D++   +   + + V+   N +GG +       + HV  GSV G
Sbjct: 593 RLLNRTSKYGNDDDYADDLMRRVFESFFRTVDGRPNSKGGQYRIEMLPTTCHVYFGSVTG 652

Query: 631 ATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEG 690
           ATPDGR AG  L++G +SP+ G D  GPTAV+KS  K+D+ + + GTLLN+KF P+ +EG
Sbjct: 653 ATPDGRRAGTPLSEG-ISPVQGADRSGPTAVIKSAGKMDH-IRTGGTLLNMKFAPSLVEG 710

Query: 691 EAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELS 750
           E G+  +A  +R++ ++   H+QFNVV ADTLR AQ  P  +  L+VRVAGYS +F +LS
Sbjct: 711 EQGISTMASLVRSYFRMDGHHVQFNVVRADTLRAAQADPDAHRDLIVRVAGYSDYFCDLS 770

Query: 751 KEIQDDIIRRTAH 763
           +E+QD+II RT H
Sbjct: 771 RELQDEIITRTEH 783



>ref|ZP_01360821.1| Formate C-acetyltransferase [Clostridium sp. OhILAs]
 gb|EAT31477.1| Formate C-acetyltransferase [Clostridium sp. OhILAs]
          Length = 849

 Score =  437 bits (1124), Expect = e-120
 Identities = 275/793 (34%), Positives = 427/793 (53%), Gaps = 41/793 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+SRLK         I+  RA   T   ++  G P +L RAK+  Y  E   + I++
Sbjct: 61  ITERLSRLKETYLKWQPTITTHRARAITKIAKENPGMPKVLLRAKSFRYCCETAPLLIQE 120

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G    +PRAG  SP++   W+  E+D    RPQD F ISEEDKR  REELFP+W+
Sbjct: 121 DELIVGAPCGQPRAGAFSPDIAWRWMEDEIDTIGNRPQDPFYISEEDKRYMREELFPFWK 180

Query: 121 KRSMKDFINGQMTD----EVKAATNTQIFSINQT----DKGQGHIIIDYPRLLNHGLGEL 172
            +S+ ++   Q  D    E+   +     S +      D   G+ +I    L+  G+ ++
Sbjct: 181 GKSVDEYCEDQYRDAGVWEISGESFVSDCSYHALNGGGDSNPGYDVI----LMKKGMIDI 236

Query: 173 VAQMQQHCQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRRE 224
             + Q+H ++     P++    ++Y+A +   E    +  R A+ A  +AA  T+ +R+ 
Sbjct: 237 QKEAQEHLEKLSYDNPDDIEKIYYYKAVIETTEGVMIYARRLADHAADLAAKETNPKRKA 296

Query: 225 ELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSL 284
           EL  I+EI+R    +KP TFW+A Q  W +  +L  E N + +S+GR DQYM PFY+  +
Sbjct: 297 ELQRISEINRRVPANKPSTFWEAIQAVWTIESLLVVEENQTGMSIGRVDQYMYPFYKADI 356

Query: 285 TQGEDAAF-LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNV 343
             G    F   EL  ++ +K ++++ + S   +++FAG+       +GG+T  G  A N 
Sbjct: 357 ESGRMTEFEAFELAGAMLIKMSEMMWVTSEGGSKFFAGYQPFVNMCVGGVTREGLDATND 416

Query: 344 LSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLN 403
           L++L +DA + V++ QP+L  R ++     +L K  + +R G G P    D+V +   L 
Sbjct: 417 LTYLLMDAVRHVKIYQPSLATRIHSKSPKKYLKKIVDVVRSGMGFPACHFDDVHIKMMLA 476

Query: 404 RGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE------------NE 451
           +GVS+EDARDY ++GCVE    GR Y     A       +E+ L+             N 
Sbjct: 477 KGVSIEDARDYCLMGCVEPQKSGRLYQWTSTAYTQWPIAIELVLNNGVPLWYGKQVTPNM 536

Query: 452 G--NAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
           G  N   TYE     ++ +I +   L    + I    HRD AP PL+S     C+E G+D
Sbjct: 537 GDINQYKTYEQFEAAVKEQIQYITKLSNIATVISQRVHRDLAPKPLMSIMYEGCMESGKD 596

Query: 510 ITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
           ++ GGA YNF  GV   G+A   DS+ A+K +VF+ ++ +  +L   LKA+F     ++V
Sbjct: 597 VSAGGAMYNFGPGVVWSGLATYVDSMAAIKKLVFDDKKYTLQQLNEALKADFV--GYDQV 654

Query: 569 RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
           ++  + +  KYGND D VD I+A+L+    KE  KY+         G+ ++S + P G +
Sbjct: 655 KSDCL-KAPKYGNDDDYVDLIAADLVNFTEKEHRKYRTLH-SIMCHGTLSISNNTPFGQL 712

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
            GAT +GR A   L+D G+SP  G D +GPTA++KSVSK+    ++ G + N K     L
Sbjct: 713 TGATANGRGAWTPLSD-GISPTQGADFKGPTAIIKSVSKMACDNMNLGMVHNFKLIAGLL 771

Query: 689 EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
           +   G   +   LR    + +  +QFN ++ +TL EAQ+ P+ Y  L+VRVAGYSAFFVE
Sbjct: 772 DTPEGEEGIITLLRTANNIGIGEMQFNYLDNNTLLEAQKHPEKYRDLIVRVAGYSAFFVE 831

Query: 749 LSKEIQDDIIRRT 761
           L K++QD+II RT
Sbjct: 832 LCKDVQDEIISRT 844



>ref|YP_855870.1| pyruvate formate-lyase [Aeromonas hydrophila subsp. hydrophila ATCC
           7966]
 gb|ABK39643.1| pyruvate formate-lyase [Aeromonas hydrophila subsp. hydrophila ATCC
           7966]
          Length = 793

 Score =  434 bits (1116), Expect = e-119
 Identities = 271/793 (34%), Positives = 422/793 (53%), Gaps = 41/793 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+ RL+         +S+ RA  +T   +   G P IL RAKA  +  E   I I+D
Sbjct: 5   LTPRLQRLRNHYLTVRPSVSIYRAQAFTEVVKANPGMPTILLRAKAFRHACETAPILIQD 64

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G+   KPRAG  SP++   W+  ELD   TRPQD F ISE DK+  REE+ P+WE
Sbjct: 65  DELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMSTRPQDPFEISEADKKTIREEIVPFWE 124

Query: 121 KRSMKDFINGQMTDEVKAATNTQIF----SINQTDKG----QGHIIIDYPRLLNHGLGEL 172
            RS+ +    Q  +    A + + F    S +Q + G     G+ ++ + + +N    + 
Sbjct: 125 GRSLDEICEAQYREAGVWAFSGETFVSDLSYHQINGGGDTCPGYDVLLFTKGMNGIKADA 184

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
            A + Q   + P++    ++Y+AA+   E    +  R A  A  +AA   DAQRR ELLT
Sbjct: 185 QAHLDQLSMENPDDIDRIYYYKAAIETCEGVVNYARRIAAHARELAAKEQDAQRRAELLT 244

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE 288
           IAE++ +   + P+T  +A Q  W +  + + E N + LSLGR DQY  P ++  + +G 
Sbjct: 245 IAEVNENVPANPPKTLQEALQSIWTVESLFEIEENQTGLSLGRVDQYCYPMFEADIREGR 304

Query: 289 ---DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLS 345
              ++A   EL+++  +KC +++ + S   A+YFAG+       +GG   +G  A N L+
Sbjct: 305 LTHESAL--ELMQAFIIKCAELMWMSSELGAKYFAGYQPFINLTVGGQKRSGGDACNDLT 362

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +L +DA + V++ QP+L  R +      ++ K  + ++ G G P    D+  +   L +G
Sbjct: 363 YLIMDAVRFVKVYQPSLACRIHNQSPQKYMEKIVDVVKAGMGFPACHFDDSHIKMMLRKG 422

Query: 406 VSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAAL--------- 456
              EDARDY ++GCVE    GR Y             +E  L  N G   L         
Sbjct: 423 FDFEDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPIAIEFVL--NRGRMVLFDSHQGLDT 480

Query: 457 -------TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
                  T+E     ++ +I+H + +   G+ I    HRD AP PL+S  +  C+E G+D
Sbjct: 481 GDLRELRTFEQFDAAVKQQIAHIVRMSAVGTVISQRVHRDVAPKPLMSLMVEGCMESGKD 540

Query: 510 ITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
           ++ GGA  N+  G+   G+A   DS+ A++ +VFE+QR + +++   L ANF   EG + 
Sbjct: 541 VSAGGAMINYGPGLIFSGLATYVDSMAAIRKLVFEEQRYTLEQIRDALLANF---EGFEA 597

Query: 569 RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
             R      KYGND + VD  + ++     KE  KY+       + G+ ++S + P+G +
Sbjct: 598 LRRDCLNAPKYGNDDNYVDQYALDITEWTEKECRKYKMLYSR-MSHGTLSISNNTPIGEL 656

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
             ATP+GR A   L+DG +SP  G D QGPTA++KSVSK++   ++ G + N KF    L
Sbjct: 657 TNATPNGRLAWMPLSDG-ISPTQGADKQGPTAIIKSVSKMNVETMNIGMVHNFKFLKGLL 715

Query: 689 EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
           + + G   L   LR  + L    +QF+ V+ + L++AQQ P+ Y  L+VRVAGYSA+FVE
Sbjct: 716 DTQEGRHGLITLLRTASILGNGQMQFSYVDNEVLKKAQQEPEKYRDLIVRVAGYSAYFVE 775

Query: 749 LSKEIQDDIIRRT 761
           L KE+QD+II RT
Sbjct: 776 LCKEVQDEIISRT 788



>ref|NP_782070.1| formate acetyltransferase 2 [Clostridium tetani E88]
 gb|AAO36007.1| formate acetyltransferase 2 [Clostridium tetani E88]
          Length = 846

 Score =  434 bits (1115), Expect = e-119
 Identities = 272/793 (34%), Positives = 420/793 (52%), Gaps = 41/793 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MT R+ +LK         I+  RA   T   ++  G P  + R K   Y  E   + I+D
Sbjct: 58  MTERLIKLKENYMKQVPSITTHRARAITKIAKENPGVPKSVLRGKCFKYCCETAPLVIQD 117

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
            ELI G    KPRAG  SP++   W+  E+D    RPQD F ISEEDK+I REELFPYW+
Sbjct: 118 NELIVGAPNGKPRAGAFSPDIAWRWMEDEIDTIANRPQDPFYISEEDKKIMREELFPYWK 177

Query: 121 KRSMKDFINGQMTD----EVKAATNTQIFSINQT----DKGQGHIIIDYPRLLNHGLGEL 172
            +S+ ++   Q  +    E+   +     S +      D   G+ +I    L+  G+ ++
Sbjct: 178 GKSVDEYCEDQYREAGVWELSGESFVSDCSYHAVNGGGDSNPGYDVI----LMKKGMLDI 233

Query: 173 VAQMQQHCQ----QQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRRE 224
             + ++       ++PE+    +FY++ +   E    +  R ++ A  +AA  TD +R+ 
Sbjct: 234 KREAEEKLASLSYERPEDIEKIYFYKSIIDTAEGVMIYAKRMSDYAAELAAKETDPKRKA 293

Query: 225 ELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSL 284
           EL  I++++     HKP TFW+A Q  W +  +L  E N + +S+GR DQYM PFY++ +
Sbjct: 294 ELQKISKVNARVPAHKPSTFWEAIQAVWTIESLLVVEENQTGMSIGRVDQYMYPFYKSDI 353

Query: 285 TQGEDAAFLK-ELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNV 343
             G    F   EL   + +K ++++ + S   +++FAG+       +GG+T  GR A N 
Sbjct: 354 ESGRMTDFEAFELAGCMLIKMSEMMWITSEGGSKFFAGYQPFVNMCVGGVTREGRDATNE 413

Query: 344 LSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLN 403
           L++L +DA + V++ QP+L  R +      +L K  + IR G G P    D+V +   L 
Sbjct: 414 LTYLLMDAVRHVKIYQPSLACRIHKGSPQKYLKKIVDVIRAGMGFPACHFDDVHIKMMLA 473

Query: 404 RGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFN--------------LLKVMEICLHE 449
           +GVS+EDARDY ++GCVE    GR Y                       L    ++C   
Sbjct: 474 KGVSIEDARDYCLMGCVEPQKSGRLYQWTSTGYTQWPICIELVLNHGVPLWYGKQVCPDM 533

Query: 450 NEGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
            + +   TYE     +R +I +        + I    HR+ AP PL+S     C+EKGR 
Sbjct: 534 GDLSQFKTYEQFEGAVREQIKYITKWTAVATTISQRVHRELAPKPLMSMMYEGCMEKGRG 593

Query: 510 ITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
           +  GGA YNF  GV   G+A  +DS+ A+K +VFE+++ + +EL   LKA+F   E  ++
Sbjct: 594 VEAGGAMYNFGPGVVWSGLATYTDSMAAIKKLVFEEKKYTLEELSEALKADFVGYE--RL 651

Query: 569 RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
           R   +    KYGND D  D I+A+L+    +E  KY+       + G+ ++S + P G +
Sbjct: 652 RKDCLEA-PKYGNDDDYADYIAADLVNFTEQEHRKYKTLYS-VLSHGTLSISNNTPFGQM 709

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
            GAT +GR A   L+DG +SP  G D +GPT+++KSVSK+    ++ G + N K     L
Sbjct: 710 TGATANGRRAWMPLSDG-ISPSQGSDFKGPTSIIKSVSKISCEDMNIGMVHNFKLMSGLL 768

Query: 689 EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
           +   G + +   LR+   L+L  IQFN ++ +TL EAQ+ P+ Y  L+VRVAGYSAFFVE
Sbjct: 769 DTPEGEQGIIALLRSACALQLGEIQFNYLDNETLIEAQKHPEQYRDLIVRVAGYSAFFVE 828

Query: 749 LSKEIQDDIIRRT 761
           L K++QD+II RT
Sbjct: 829 LCKDVQDEIISRT 841



>ref|ZP_00801006.1| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF]
 gb|EAO80999.1| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF]
          Length = 789

 Score =  433 bits (1113), Expect = e-119
 Identities = 269/797 (33%), Positives = 427/797 (53%), Gaps = 44/797 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T RI   +         IS ERA ++T SH++TEGE V++RRAKA     E + ++I  
Sbjct: 2   ITERIESSRQNYINAKPAISYERARIWTESHKKTEGESVVIRRAKAFRDTCEQINVTIFG 61

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELI G+     + GI++PE    W+ +E+D F  R QD + +++E +   R+++FPYW+
Sbjct: 62  EELIVGSIGEFRKCGILTPEFSWTWVDREMDNFDERVQDPYVMTDEQRTFVRKKIFPYWK 121

Query: 121 KRSMKDFINGQMTDEV-KAATNTQIF-SINQTDKGQGHIIIDYPRLL-NHGLGELVAQMQ 177
            +S+++    Q+ ++  K A +T I  + ++  +  G +  DY  +L   G G ++ + +
Sbjct: 122 GKSLEEAFLAQLPEKTAKVAVDTGIVDNDSKWRQAVGEMTPDYQDVLFKKGFGGIIKEAK 181

Query: 178 QH--------CQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTI 229
           +H         +   +  FY + ++  E       RY + A  MA    +  R+ ELL I
Sbjct: 182 EHIIKLSLTSAEDMKKKDFYNSIIITSEGMITLANRYGQKATEMADIENNPIRKGELLKI 241

Query: 230 AEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG-- 287
           A+I     ++ P TF++A Q  W+  +      N  +L++GRFDQ+M P+Y++ + +G  
Sbjct: 242 ADICGRIPENPPDTFYEAIQFVWFTQVGGIISENPLALNIGRFDQFMYPYYKSDVDKGII 301

Query: 288 -EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSF 346
            +D A  +EL+E+LW+K ++ V   S ++A +FAG+       +GG T  G+ A N LS+
Sbjct: 302 TKDEA--QELIEALWIKLSEWVWTISANTAEFFAGYNQFQNLTVGGKTREGKDATNDLSY 359

Query: 347 LCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGV 406
           +CL A + V+  QP L VR +      FL      +  GTG P I ND       +N G 
Sbjct: 360 MCLKATERVKTHQPGLSVRVHQDSPRSFLDAVTHLVSKGTGFPAIHNDTAGYQMLINAGY 419

Query: 407 SLEDARDYSVVGCVELSIPG--RTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGL--- 461
             EDARD++  GCV   +P   +T         N    +E  L  N+G + +T E +   
Sbjct: 420 EPEDARDWNNCGCV---VPHFRKTGEWTSAVNINFTAALEFAL--NQGESRITGEKIGMD 474

Query: 462 ---------LEQIRAKISHYITLMVEGSNICDIG----HRDWAPVPLLSSFISDCLEKGR 508
                     E++          ++E S I  +     H++  P P LSS I +C+ KG+
Sbjct: 475 EDKPTTFQSYEEVEKAFYKQFDNLIEHSIIATLLAQKLHKEMVPRPFLSSCIEECMIKGK 534

Query: 509 DITDGGARYNFSGV-QGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
           D+ D GA+YN   V  GIG+A  S+SL  +K +VFE +  + + L+  L AN+   EG +
Sbjct: 535 DLVDAGAKYNLGPVLTGIGLAVTSNSLAVIKKLVFEDKMTTMETLIKALDANW---EGYE 591

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGS 627
              +L     KYGN++D VD+I+ ++  +Y K+  KY++  G  F      +S ++P G 
Sbjct: 592 KLRQLAVSVPKYGNNVDYVDDIAIKIANYYYKQGHKYKDINGNNFNTAFMGISNYLPTGK 651

Query: 628 VVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPAT 687
           VVGATP GR A E L++G +SP  G D   P   ++S +KL+  + S GTLLN++     
Sbjct: 652 VVGATPCGRKAKEPLSEG-VSPFAGSDTSTPLEAMRSAAKLNQDVHSGGTLLNLRLNEDL 710

Query: 688 LEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
           +  + G   L   +++F  L   H+QFN ++ DTLR+AQ  PQDY  L+VRVAGYS  FV
Sbjct: 711 VNTKRGQSNLGFMIQSFFALGAFHVQFNTISTDTLRKAQNNPQDYKDLLVRVAGYSTQFV 770

Query: 748 ELSKEIQDDIIRRTAHQ 764
            LSK +Q+ II RTAH+
Sbjct: 771 NLSKSMQEAIIARTAHE 787



>ref|ZP_01352245.1| Formate C-acetyltransferase [Clostridium phytofermentans ISDg]
 gb|EAT24356.1| Formate C-acetyltransferase [Clostridium phytofermentans ISDg]
          Length = 848

 Score =  430 bits (1106), Expect = e-118
 Identities = 268/793 (33%), Positives = 426/793 (53%), Gaps = 41/793 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+ +LK     +   I+  RA   T   ++  G P I+ RAK   Y  E   + I+D
Sbjct: 60  ITPRLHKLKENYLTHKPTITTYRARAITKIAKENPGMPKIMLRAKCFRYCCETAPLVIQD 119

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
            ELI G     PRAG  SP++   W++ E+D   TRPQD F ISEEDK+I +EELFP+W 
Sbjct: 120 NELIVGAPCGAPRAGAFSPDIAWRWMVDEIDTIGTRPQDPFYISEEDKKIMKEELFPFWA 179

Query: 121 KRSMKDFINGQMTDEVKAATNTQIF-------SINQT-DKGQGHIIIDYPRLLNHGLGEL 172
            +S+ ++   Q  +      + + F       +IN   D   G+ +I    L+  G+ ++
Sbjct: 180 GKSVDEYCEDQYREAGVWELSGESFVSDCSYHAINGGGDSNPGYDVI----LMKKGMLDI 235

Query: 173 VAQMQQHCQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRRE 224
             + + H ++     P++    +FY++ +   E    +  R +E A  +AA  T+ +R+E
Sbjct: 236 QQEAKDHLKELDYENPDDIEKIYFYKSIIDTTEGVMIYAKRLSEYAAELAAKETNPKRKE 295

Query: 225 ELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSL 284
           ELL I+E++ +   HKP+TFW+A Q  W +  +L  E N + +S+GR DQYM PFY+  +
Sbjct: 296 ELLKISEVNAYVPAHKPRTFWEAIQAVWTIESLLVVEENQTGMSIGRVDQYMYPFYKDDI 355

Query: 285 TQGEDAAFLK-ELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNV 343
             G    +   EL   + +K ++++ + S   +++FAG+       +GG+T +GR A N 
Sbjct: 356 ESGRMNDYQAFELAGCMLIKMSEMMWITSEGGSKFFAGYQPFVNMCVGGVTRSGRDATND 415

Query: 344 LSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLN 403
           L++L +DA + V++ QP+L  R +      +L K  + +R G G P    D+  +   L 
Sbjct: 416 LTYLLMDAVRHVKIYQPSLACRIHNKSPKEYLKKIVDVVRSGMGFPACHFDDAHIKMMLA 475

Query: 404 RGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN----------EGN 453
           +GVS+EDARDY ++GCVE    GR Y     A       +E+ L+               
Sbjct: 476 KGVSIEDARDYCLMGCVEPQKSGRLYQWTSTAYTQWPICIELVLNNGVPLWYGKQVCPDM 535

Query: 454 AALTYEGLLEQIRAKISHYITLMVEGSNICDIG----HRDWAPVPLLSSFISDCLEKGRD 509
            AL+     E+  A +   I  + + S++  +     HRD AP PL+S     C+E  +D
Sbjct: 536 GALSNFKTYEEFEAAVKEQIKYITKWSDVATVISQRIHRDLAPKPLMSIMYEGCMESAKD 595

Query: 510 ITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
           ++ GGA YNF  GV   G+A  SDS+ A+K +VF++++ + ++L   LKA+FA  +  ++
Sbjct: 596 VSAGGAMYNFGPGVVWSGLATYSDSMAAIKKLVFDEKKYTLEQLNEALKADFAGYD--QI 653

Query: 569 RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
           R   +N   KYGND D  D I+A+L+     E  KY+         G+ ++S + P G +
Sbjct: 654 RTDCLNA-PKYGNDDDYADLIAADLVDFTEHEHRKYKTLYS-ILCHGTLSISNNTPFGQL 711

Query: 629 VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
            GA+ +GR A   L+DG +SP  G D  GPTA++KS+SK+ N  ++ G + N K     L
Sbjct: 712 TGASANGRHAWLPLSDG-ISPTQGADFNGPTAIIKSISKMANDSMNLGMVHNFKIMSGLL 770

Query: 689 EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
           +   G   L   LR         +QFN ++ +TL +AQ+ P+ Y  L+VRVAGYSAFF+E
Sbjct: 771 DTPEGEESLITLLRTACMFGNGEMQFNYLDNNTLIDAQKHPEKYRDLIVRVAGYSAFFIE 830

Query: 749 LSKEIQDDIIRRT 761
           L K++QD+II RT
Sbjct: 831 LCKDVQDEIISRT 843



>ref|YP_543898.1| hypothetical protein UTI89_C4964 [Escherichia coli UTI89]
 ref|YP_672437.1| hypothetical protein ECP_4600 [Escherichia coli 536]
 emb|CAD42073.1| hypothetical protein [Escherichia coli]
 gb|ABE10367.1| hypothetical protein UTI89_C4964 [Escherichia coli UTI89]
 gb|ABG72536.1| hypothetical protein ECP_4600 [Escherichia coli 536]
          Length = 1140

 Score =  428 bits (1100), Expect = e-118
 Identities = 270/793 (34%), Positives = 420/793 (52%), Gaps = 41/793 (5%)

Query: 1    MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
            +T RI RL+         +S+ RAL +T   +   G P IL RAKA  +  E   I I+D
Sbjct: 352  LTPRIQRLRNHYLTVRPSVSIYRALAFTEVVKANPGMPTILLRAKAFRHACETAPILIQD 411

Query: 61   EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
            +ELI G+   KPRAG  SP++   W+  ELD   TRPQD F ISEEDK+  REE+ P+WE
Sbjct: 412  DELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMSTRPQDPFEISEEDKKTIREEIVPFWE 471

Query: 121  KRSMKDFINGQMTD----EVKAATNTQIFSINQTDKG----QGHIIIDYPRLLNHGLGEL 172
             RS+ +    Q  +         T     S +Q + G     G+ ++ + + +N    + 
Sbjct: 472  GRSLDEICEAQYREAGVWSFSGETFVSDLSYHQVNGGGDTCPGYDVLLFTKGMNGIKADA 531

Query: 173  VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
             A + +   + PE+    ++Y+AA+   E    +  R A  A  +AA   +AQRR ELLT
Sbjct: 532  EAHLAELSMENPEDIDRIYYYKAAIDTCEGVINYAHRIAARARELAAVEQNAQRRAELLT 591

Query: 229  IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG- 287
            IAE++++   + P+T  +A Q  W +  + + E N + LSLGR DQY  P ++  + +G 
Sbjct: 592  IAEVNQNVPANPPKTLQEALQSIWTVESLFEIEENQTGLSLGRVDQYCYPMFEADIREGR 651

Query: 288  --EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLS 345
               + A   EL+++  +KC +++ + S   A+YFAG+       +GG   +G  A N L+
Sbjct: 652  LTHEGAL--ELMQAFIIKCAELMWMSSELGAKYFAGYQPFINLTVGGQKRSGGDACNDLT 709

Query: 346  FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
            +L +DA + V++ QP+L  R +      ++ K  + ++ G G P    D+  +   L +G
Sbjct: 710  YLIMDAVRFVKVYQPSLACRIHNQSPQKYMEKIVDVVKAGMGFPACHFDDSHIKMMLRKG 769

Query: 406  VSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAAL--------- 456
               EDARDY ++GCVE    GR Y             +E  L  N G   L         
Sbjct: 770  FDFEDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPIAIEFVL--NRGRMVLFDSYQGLDT 827

Query: 457  -------TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
                   T+E     ++ +++H I L   G+ I    HRD AP PL+S  +  C+EKG+D
Sbjct: 828  GDLKDLRTFEDFDAAVKKQVAHIIRLSAIGTVISQRVHRDVAPKPLMSLLVEGCMEKGKD 887

Query: 510  ITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
            ++ GGA  N   G+   G+A   DS+ A++ +V+E ++ + +++   L ANF   EG  +
Sbjct: 888  VSAGGAMVNHGPGLIFSGLATYVDSMAAIRKLVYEDKKYTLEQIRDALLANFEGYEG--L 945

Query: 569  RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
            R   +N   KYGND + VD  + ++     +E  KY+       + G+ ++S + P+G +
Sbjct: 946  RRDCLNA-PKYGNDDNYVDQYALDITEWTERECRKYK-MLYSTLSHGTLSISNNTPIGEL 1003

Query: 629  VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
              ATP+GR A   L+D G+SP  G D  GPTA++KSVSK++   ++ G + N KF    L
Sbjct: 1004 TNATPNGRLAWMPLSD-GISPTQGADKHGPTAIIKSVSKMNVETMNIGMVHNFKFLKGLL 1062

Query: 689  EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
            +   G   L   LR  + L    +QF+ V+ + L++AQQ P+ Y  L+VRVAGYSA+FVE
Sbjct: 1063 DTPEGRHGLITLLRTASILGNGQMQFSYVDNEVLKKAQQEPEKYRDLIVRVAGYSAYFVE 1122

Query: 749  LSKEIQDDIIRRT 761
            L KE+QD+II RT
Sbjct: 1123 LCKEVQDEIISRT 1135




 Score = 71.2 bits (173), Expect = 2e-10
 Identities = 81/368 (22%), Positives = 151/368 (41%), Gaps = 61/368 (16%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+  L   L A+   + +E A + +       G P  ++ A+    ++  + +++  
Sbjct: 18  LTPRVKVLAERLLAHPSTLCVEHAGILSGLDGDIAGIPAAVKPARRFYELMRQLPLAVSP 77

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI GN+T +P                             AI  ++   +R  +F +  
Sbjct: 78  DELIVGNQTHRPHG---------------------------AIFHDESTAHRPSVFQFLN 110

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
             S  D        + K      + +I Q  + +              LG  V++     
Sbjct: 111 LNSDLD------APDYKLVIEKGVLAIKQQLEEK-----------TRSLGSAVSR----- 148

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
               E +  +AA+   +A  +     A  AE +AA  T+A R+ EL   A I  H     
Sbjct: 149 SGMDEVNACRAAIYACDALMQLAQNLATSAEKLAATETNAYRKAELSESAAILHHIPARP 208

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG---EDAAFLKELL 297
            ++F +ACQ F+   + LQ ++ + +++    D+ +L +YQ  +  G   E  A+  E++
Sbjct: 209 ARSFKEACQAFYLFQLALQLDNGSYAVNPEGADKALLAYYQHDIANGLLTEAQAY--EIV 266

Query: 298 ESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQL 357
           E LW K  ++  +R+  +     G+P     L G   EN  + +N LS + L+A ++  L
Sbjct: 267 ECLWFKLAELSEVRAACA---IDGYPMFDALLHGASLEN--AVINPLSEMFLNAQRN--L 319

Query: 358 PQPNLGVR 365
              NL +R
Sbjct: 320 SALNLPIR 327



>ref|ZP_00726050.1| COG1882: Pyruvate-formate lyase [Escherichia coli F11]
          Length = 1128

 Score =  428 bits (1100), Expect = e-118
 Identities = 270/793 (34%), Positives = 420/793 (52%), Gaps = 41/793 (5%)

Query: 1    MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
            +T RI RL+         +S+ RAL +T   +   G P IL RAKA  +  E   I I+D
Sbjct: 340  LTPRIQRLRNHYLTVRPSVSIYRALAFTEVVKANPGMPTILLRAKAFRHACETAPILIQD 399

Query: 61   EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
            +ELI G+   KPRAG  SP++   W+  ELD   TRPQD F ISEEDK+  REE+ P+WE
Sbjct: 400  DELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMSTRPQDPFEISEEDKKTIREEIVPFWE 459

Query: 121  KRSMKDFINGQMTD----EVKAATNTQIFSINQTDKG----QGHIIIDYPRLLNHGLGEL 172
             RS+ +    Q  +         T     S +Q + G     G+ ++ + + +N    + 
Sbjct: 460  GRSLDEICEAQYREAGVWSFSGETFVSDLSYHQVNGGGDTCPGYDVLLFTKGMNGIKADA 519

Query: 173  VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
             A + +   + PE+    ++Y+AA+   E    +  R A  A  +AA   +AQRR ELLT
Sbjct: 520  EAHLAELSMENPEDIDRIYYYKAAIDTCEGVINYAHRIAARARELAAVEQNAQRRAELLT 579

Query: 229  IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG- 287
            IAE++++   + P+T  +A Q  W +  + + E N + LSLGR DQY  P ++  + +G 
Sbjct: 580  IAEVNQNVPANPPKTLQEALQSIWTVESLFEIEENQTGLSLGRVDQYCYPMFEADIREGR 639

Query: 288  --EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLS 345
               + A   EL+++  +KC +++ + S   A+YFAG+       +GG   +G  A N L+
Sbjct: 640  LTHEGAL--ELMQAFIIKCAELMWMSSELGAKYFAGYQPFINLTVGGQKRSGGDACNDLT 697

Query: 346  FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
            +L +DA + V++ QP+L  R +      ++ K  + ++ G G P    D+  +   L +G
Sbjct: 698  YLIMDAVRFVKVYQPSLACRIHNQSPQKYMEKIVDVVKAGMGFPACHFDDSHIKMMLRKG 757

Query: 406  VSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAAL--------- 456
               EDARDY ++GCVE    GR Y             +E  L  N G   L         
Sbjct: 758  FDFEDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPIAIEFVL--NRGRMVLFDSYQGLDT 815

Query: 457  -------TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
                   T+E     ++ +++H I L   G+ I    HRD AP PL+S  +  C+EKG+D
Sbjct: 816  GDLKDLRTFEDFDAAVKKQVAHIIRLSAIGTVISQRVHRDVAPKPLMSLLVEGCMEKGKD 875

Query: 510  ITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKV 568
            ++ GGA  N   G+   G+A   DS+ A++ +V+E ++ + +++   L ANF   EG  +
Sbjct: 876  VSAGGAMVNHGPGLIFSGLATYVDSMAAIRKLVYEDKKYTLEQIRDALLANFEGYEG--L 933

Query: 569  RARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSV 628
            R   +N   KYGND + VD  + ++     +E  KY+       + G+ ++S + P+G +
Sbjct: 934  RRDCLNA-PKYGNDDNYVDQYALDITEWTERECRKYK-MLYSTLSHGTLSISNNTPIGEL 991

Query: 629  VGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATL 688
              ATP+GR A   L+D G+SP  G D  GPTA++KSVSK++   ++ G + N KF    L
Sbjct: 992  TNATPNGRLAWMPLSD-GISPTQGADKHGPTAIIKSVSKMNVETMNIGMVHNFKFLKGLL 1050

Query: 689  EGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
            +   G   L   LR  + L    +QF+ V+ + L++AQQ P+ Y  L+VRVAGYSA+FVE
Sbjct: 1051 DTPEGRHGLITLLRTASILGNGQMQFSYVDNEVLKKAQQEPEKYRDLIVRVAGYSAYFVE 1110

Query: 749  LSKEIQDDIIRRT 761
            L KE+QD+II RT
Sbjct: 1111 LCKEVQDEIISRT 1123




 Score = 71.2 bits (173), Expect = 2e-10
 Identities = 81/368 (22%), Positives = 151/368 (41%), Gaps = 61/368 (16%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+  L   L A+   + +E A + +       G P  ++ A+    ++  + +++  
Sbjct: 6   LTPRVKVLAERLLAHPSTLCVEHAGILSGLDGDIAGIPAAVKPARRFYELMRQLPLAVSP 65

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI GN+T +P                             AI  ++   +R  +F +  
Sbjct: 66  DELIVGNQTHRPHG---------------------------AIFHDESTAHRPSVFQFLN 98

Query: 121 KRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQHC 180
             S  D        + K      + +I Q  + +              LG  V++     
Sbjct: 99  LNSDLD------APDYKLVIEKGVLAIKQQLEEK-----------TRSLGSAVSR----- 136

Query: 181 QQQPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIAEISRHNAQHK 240
               E +  +AA+   +A  +     A  AE +AA  T+A R+ EL   A I  H     
Sbjct: 137 SGMDEVNACRAAIYACDALMQLAQNLATSAEKLAATETNAYRKAELSESAAILHHIPARP 196

Query: 241 PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG---EDAAFLKELL 297
            ++F +ACQ F+   + LQ ++ + +++    D+ +L +YQ  +  G   E  A+  E++
Sbjct: 197 ARSFKEACQAFYLFQLALQLDNGSYAVNPEGADKALLAYYQHDIANGLLTEAQAY--EIV 254

Query: 298 ESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQL 357
           E LW K  ++  +R+  +     G+P     L G   EN  + +N LS + L+A ++  L
Sbjct: 255 ECLWFKLAELSEVRAACA---IDGYPMFDALLHGASLEN--AVINPLSEMFLNAQRN--L 307

Query: 358 PQPNLGVR 365
              NL +R
Sbjct: 308 SALNLPIR 315



>ref|ZP_00800234.1| Pyruvate formate-lyase [Alkaliphilus metalliredigenes QYMF]
 gb|EAO81728.1| Pyruvate formate-lyase [Alkaliphilus metalliredigenes QYMF]
          Length = 806

 Score =  425 bits (1092), Expect = e-117
 Identities = 264/795 (33%), Positives = 433/795 (54%), Gaps = 39/795 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           MT RI  ++  +  +   +  ERALL T ++ +TE  P + RRA A   IL ++  +I +
Sbjct: 16  MTPRIEAMRKEIVHSKPILCSERALLVTEAYAETEALPSVTRRAFALKKILGNMTQNIFE 75

Query: 61  EELIAGNRTVKPRAGI-MSPEMDPYWLLKELDQF-PTRPQDRFAISEEDKRIYREELFPY 118
            ELI G+     R    + PE    WL +ELD+   TR QD F + +  K   ++ +FPY
Sbjct: 76  GELIVGSHGSNGRRSAPVFPEFSTKWLEEELDEILETRTQDTFIVPKNVKEDLKD-IFPY 134

Query: 119 WEKRSMKDFINGQMTDEVKAATNTQIFSINQTDK-GQGHIIIDYPRLLNHGLGELVAQMQ 177
           W  +++ D     + DE K A +  +F+    ++ G GH   D P+LL  GL  + +++ 
Sbjct: 135 WRGKTIHDRYRAMLPDETKRARDAYMFTRGLFEQNGYGHTAYDIPKLLKVGLVGIKSEVN 194

Query: 178 QHCQQQP--------ENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTI 229
           +  Q           +  FY+  ++  ++   +  RYA+ A  +A    +  R++EL  I
Sbjct: 195 EKMQTLDLTTSEGLEKKLFYEGLIVCCDSVIAYAKRYAQRALELADQEKNPVRKKELEKI 254

Query: 230 AEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGED 289
           A++ +   ++  +  W A Q+  +M +I+Q E+N  S+  GR DQY+  +Y+  + +G  
Sbjct: 255 ADVCQWVPENPARDTWDAIQVVAFMQLIIQTETNGDSVCPGRLDQYLYSYYKNDMAEGRY 314

Query: 290 AAF-LKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFLC 348
               ++ELL+ LW+K N+I+ ++++ S R   GFP   T  +GG T  G  A N LS+L 
Sbjct: 315 TIDEIQELLDCLWIKLNEIIKIQASESVRIHPGFPMTPTVTIGGQTPEGEDATNELSYLM 374

Query: 349 LDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG--- 405
           L++ + ++L  P   VR +      F ++  E ++ GTG+P +F DE  + A L RG   
Sbjct: 375 LNSQEHIRLTNPQFTVRFHKDTPEDFKLRVVEVVKLGTGMPAMFGDEACIAA-LKRGCPD 433

Query: 406 VSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALT-------- 457
           + +E  RDY +VGCVEL+ P    G  +    N+ +V+++ L  N G   LT        
Sbjct: 434 MPMERIRDYRIVGCVELA-PRGFQGRVNGGFLNVARVVDLAL--NNGVDRLTNEQIGPQT 490

Query: 458 --------YEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRD 509
                   ++ +L  +R + ++++   V  + + D+  R+  P   LSS +  C+E G+D
Sbjct: 491 GAPEDLKDFDDVLTAVRTQTAYFVKHQVINAAVVDMVQREHTPHLFLSSLVEGCIENGKD 550

Query: 510 ITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVR 569
           +T GG+ +  + +  +G A  +DSL  +K  VF+ Q +S  EL  +L +NFA  +GEK+ 
Sbjct: 551 MTQGGSLWGGTPILHVGEATAADSLIGVKKAVFDDQLISMKELKEILDSNFAGAQGEKIY 610

Query: 570 ARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVV 629
             L+    KYGND D  D +  +++  +  E+EK+++  G ++T    T+ A VP G   
Sbjct: 611 QALL-AMPKYGNDDDYADEVMQKMINIFFDEIEKHKDIDGRFYTSTILTLGATVPHGWTT 669

Query: 630 GATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLE 689
           GAT +GR A   +AD  +S   G D +GPTA+L S SK+D T    G ++N+KFT   LE
Sbjct: 670 GATANGRKATMPVAD-SMSASNGADKEGPTAMLLSASKIDQTRTIEGNVVNLKFTKMALE 728

Query: 690 GEAGLRKLADFLRA-FTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVE 748
            +  L++L + +   F  LK Q IQ NVV+  TL++AQ+ P+ +  L++RVAGYSA F E
Sbjct: 729 EKKNLQQLVNLVSVYFDDLKGQEIQVNVVDESTLKDAQEYPEKHQDLIIRVAGYSARFTE 788

Query: 749 LSKEIQDDIIRRTAH 763
           L+KE+QDDIIRRT +
Sbjct: 789 LAKELQDDIIRRTEY 803



>ref|ZP_01149160.1| Formate C-acetyltransferase [Desulfotomaculum reducens MI-1]
 gb|EAR43404.1| Formate C-acetyltransferase [Desulfotomaculum reducens MI-1]
          Length = 847

 Score =  421 bits (1082), Expect = e-116
 Identities = 268/790 (33%), Positives = 412/790 (52%), Gaps = 35/790 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+ RL+         +S+ RA+ +T   ++  G P IL RAK      E   + I+ 
Sbjct: 59  LTPRLERLRANYLKVKPSVSIYRAIAFTQVTKENPGLPKILLRAKCFRKACETAPLVIQK 118

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G+   KPRAG +SP++   W+  ELD   TRPQD F ISEEDKRI REE+FPYWE
Sbjct: 119 DELIVGHPCGKPRAGAVSPDIAWRWIRDELDTMSTRPQDPFEISEEDKRILREEIFPYWE 178

Query: 121 KRSMKDFINGQMTDEVKAATNTQIF----SINQTDKG----QGHIIIDYPRLLNHGLGEL 172
            +S+ +    Q  +    +   + F    S +Q + G     G+ II   + +N    E 
Sbjct: 179 GKSLDEVCQNQYEEAGLWSFTGEAFVSDLSYHQVNGGGDTCPGYDIILIKKGINGVRQEA 238

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
           V ++ +   + PE+    +FY+A +   +    +  R ++ A  +AA   DA R++EL  
Sbjct: 239 VERLSKLSMENPEDIDKIYFYKAEIETCDGILAYAKRLSDYARELAAREHDANRQKELYK 298

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE 288
           I++I  H   + P+TF +A Q  W +  +   E N + +SLGR DQY+ P ++  +  G 
Sbjct: 299 ISDILTHVPANPPRTFHEALQSIWTLESLFVVEENQTGISLGRLDQYIYPMFKADMDAGR 358

Query: 289 -DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFL 347
            +     ELL    +KC++++ L S   A+YFAG+       +GG    G  A N L++L
Sbjct: 359 MNKLEAFELLSCFIIKCSEVMWLSSELGAKYFAGYQPFVNCTVGGQKRTGGDATNDLTYL 418

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
            +DA +  ++ QP+L  R +      +L K  + ++ G G P    D+  +   L +G  
Sbjct: 419 IMDAVRFTKMYQPSLACRIHNKSPQKYLKKIVDVVKAGLGFPACHFDDSHIKMMLAKGFG 478

Query: 408 LEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE--------------NEGN 453
           +EDARDY ++GCVE    GR Y             +E  L                 + +
Sbjct: 479 IEDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPIAIEFVLRRGIMKWHGTLQGIDTGDLD 538

Query: 454 AALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDG 513
              TYE      + +I H I +   G+ I    HR+ AP PL+S  +  C+EKG D+T G
Sbjct: 539 NFKTYEEFDAACKKQIEHIIRMSAIGTIISQRVHRELAPKPLMSLLVEGCMEKGTDVTHG 598

Query: 514 GARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEG-EKVRAR 571
           GA  N   G+   G+   +DS+ A+K +VF+ ++ +  ++   L ANF   EG E +R  
Sbjct: 599 GALVNSGPGLIFSGLGTYADSMAAIKKLVFDDKKYTLKQIRDALDANF---EGYETIRTD 655

Query: 572 LINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGA 631
            +N   KYGND D VD I+A+L+  + + V         +F+ G+ ++S + P+G + GA
Sbjct: 656 CLNA-PKYGNDDDYVDEIAADLIT-WTERVHNTFKMLYSHFSHGTLSISNNTPIGEITGA 713

Query: 632 TPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGE 691
           + +GR A   L+D G+SP  G D  GPTA++KSVSKL N  ++ G + N K     LE  
Sbjct: 714 SANGRLAWAPLSD-GISPTQGADKLGPTAIIKSVSKLSNESMNIGMVHNFKLLRGILETP 772

Query: 692 AGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSK 751
            G   L   LR  + L    +QF+ V+ + L++AQ  P  Y  L++RVAGYSA+FVEL K
Sbjct: 773 EGENGLITLLRTASILGNGQMQFSYVDNEVLKKAQLEPDKYRDLIIRVAGYSAYFVELCK 832

Query: 752 EIQDDIIRRT 761
           E+QD+II RT
Sbjct: 833 EVQDEIISRT 842



>ref|ZP_00800648.1| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF]
 gb|EAO81343.1| Formate C-acetyltransferase [Alkaliphilus metalliredigenes QYMF]
          Length = 845

 Score =  421 bits (1081), Expect = e-115
 Identities = 266/791 (33%), Positives = 417/791 (52%), Gaps = 37/791 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+  LK         IS+ RA   T   ++  G P IL RAK+  Y  E   + I+D
Sbjct: 57  ITERLKTLKDNYLKWKPSISIHRARAITKIAKENPGMPKILLRAKSFRYCCETAPLVIQD 116

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
            ELI G     PRAG  SP++   WL +ELD    R QD F ISEEDK+   EE+FPYW+
Sbjct: 117 HELIVGAPCGAPRAGAFSPDISWRWLEEELDTIANRSQDPFYISEEDKKELVEEIFPYWK 176

Query: 121 KRSMKDFINGQMTD----EVKAATNTQIFSINQT----DKGQGHIIIDYPRLLNHGLGEL 172
            +S+ +    Q  +    E+   +     S +      D   G+ +I   + +     E 
Sbjct: 177 GKSVDEHSEDQFREAGVWEISGESFVSDCSYHALNGGGDSNPGYDVILMKKGMLDIQEEA 236

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
             ++ +   + PE+    +FY++ +   E    +  R +E A  +A   ++  R+ EL+ 
Sbjct: 237 KEKLNELSYENPEDIEKIYFYKSVIQTTEGVMVYARRLSEYAMELAQKESNPNRKAELMK 296

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG- 287
           IAE+++    HKP  FW+A Q  W +  +L  E N + +S+GR DQYM PF++  L  G 
Sbjct: 297 IAEVNKRVPAHKPNNFWEAIQSVWTVESLLVVEENQTGMSIGRVDQYMHPFFEQDLKNGN 356

Query: 288 --EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLS 345
             E  AF  EL  S+ +K ++++ L S  S+++FAG+       +GG+T  G  A N L+
Sbjct: 357 LSEYEAF--ELAGSMLIKMSEMMWLTSEGSSKFFAGYQPFINMCVGGVTREGLDATNDLT 414

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +L +DA + V++ QP+L  R ++     +L K  + +R G G P    D+V +   L +G
Sbjct: 415 YLLMDAVRHVKIYQPSLATRIHSKSPKKYLRKIVDVVRSGMGFPACHFDDVHIKMMLAKG 474

Query: 406 VSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE--------------NE 451
           VS+EDARDY ++GCVE    GR Y     A       +E+ L++               +
Sbjct: 475 VSIEDARDYCLMGCVEPQKSGRLYQWTSTAYTQWPICIELALNKGIPLWYGKKVCPDTGD 534

Query: 452 GNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDIT 511
            +   +YE   + ++ +I++   L    + I    HR+ AP PL+S     C+EKG+D++
Sbjct: 535 VDGFASYEDFEKAVKEQINYITKLSSIATVITQRVHRELAPKPLMSIMYEGCMEKGKDVS 594

Query: 512 DGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRA 570
            GGA YNF  GV   G+A   DS+ A+K +VF++++ +F +L   L  +F   EG +   
Sbjct: 595 SGGAMYNFGPGVVWSGLATYVDSMAAIKKLVFDEKKYTFKQLNEALNKDF---EGHEELR 651

Query: 571 RLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVG 630
               +  KYGND D  D I+ +L+ +   E  KY+       + G+ ++S + P G + G
Sbjct: 652 NDCLKAPKYGNDDDYADLIAVDLVNYTENEHRKYKT-LYSVLSHGTLSISNNTPFGQLTG 710

Query: 631 ATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEG 690
           A+ +GR A   L+D G+SP  G D +GPTA +KSVSK+    ++ G + N K     L+ 
Sbjct: 711 ASANGRKAWAPLSD-GISPTQGADFKGPTATIKSVSKMACDNMNIGMVHNFKLMSGLLDT 769

Query: 691 EAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELS 750
             G   +   LR  + L +  +QFN ++ +TL +AQ+ P+ Y  L+VRVAGYSAFFVEL 
Sbjct: 770 PEGEEGIVTLLRTASMLGVGEMQFNYLDNETLIKAQKNPEQYRDLIVRVAGYSAFFVELC 829

Query: 751 KEIQDDIIRRT 761
           K++QD+II RT
Sbjct: 830 KDVQDEIISRT 840



>ref|YP_389771.1| Formate C-acetyltransferase [Desulfovibrio desulfuricans G20]
 gb|ABB40076.1| Formate C-acetyltransferase [Desulfovibrio desulfuricans G20]
          Length = 846

 Score =  418 bits (1074), Expect = e-115
 Identities = 266/794 (33%), Positives = 418/794 (52%), Gaps = 45/794 (5%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T R  +LK         I+++RA+  T   ++  G P  L RAK   Y  E   + I+D 
Sbjct: 59  TPRHVKLKENFLKQVPSITVQRAVAITKIAKENPGLPKPLLRAKTFRYCCETAPLVIQDH 118

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+    PRAG  SPE+   WL  ELD   +RPQD F ISEEDK++ REE+FP+W+ 
Sbjct: 119 ELIVGSPNGAPRAGAFSPEVAWRWLQDELDTIGSRPQDPFYISEEDKKVLREEVFPFWQN 178

Query: 122 RSMKDFINGQMTD----EVKAATNTQIFSINQT----DKGQGHIIIDYPRLLNHGLGELV 173
           +S+ +F  GQ  +    E+   +     S +      D   G+ +I    L+  G+ ++ 
Sbjct: 179 KSVDEFCEGQYREADLWEMSGESFVSDCSYHAVNGGGDSNPGYDVI----LMKKGMLDIQ 234

Query: 174 AQMQQHCQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREE 225
            + ++  +Q     PE+    +FY++ +   E    +  R +  A  +AA  TD +R+ E
Sbjct: 235 REAREKLEQLDYANPEDIDKIYFYKSVIETAEGVMIYARRLSAYAAELAARETDPRRKAE 294

Query: 226 LLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLT 285
           L  I+E++     H P  FW+A Q  W +  +L  E N + +S+GR DQYM PFY+  + 
Sbjct: 295 LQKISEVNARVPAHAPSNFWEAIQAVWTVESLLVVEENQTGMSIGRVDQYMYPFYRADID 354

Query: 286 QG---EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVN 342
            G   E  AF  +L   + VK ++++ + S  ++++FAG+       +GG+T  G  A N
Sbjct: 355 SGRLTEYEAF--DLAGCMLVKMSEMMWITSEGASKFFAGYQPFVNMCVGGVTREGHDATN 412

Query: 343 VLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFL 402
            L+++ +DA + V++ QP L  R +      +L K  + IR G G P +  D+  +   L
Sbjct: 413 DLTYMLMDAVRHVRIYQPTLATRVHNKSPQKYLKKIVDVIRSGMGFPAVHFDDAHIKMML 472

Query: 403 NRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE----------NEG 452
            +GVS+EDARDY ++GCVE    GR Y             +E+ L+              
Sbjct: 473 AKGVSIEDARDYCLMGCVEPQKSGRLYQWTSTGYTQWPICIELVLNHGVPLWYGKKVTPD 532

Query: 453 NAALTYEGLLEQIRAKISHYITLMVEGSNICDI----GHRDWAPVPLLSSFISDCLEKGR 508
              L+     E+  A +   I  + + +++  +     HR+ AP PL+S     C+E GR
Sbjct: 533 MGDLSQYDTYEKFEAAVKEQIRWITKNTSVATVISQRAHRELAPKPLMSLMYEGCMESGR 592

Query: 509 DITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
           D++ GGA YNF  GV   G+A   DS+ A+K +V++ ++ +  +L   LKA+FA    ++
Sbjct: 593 DVSAGGAMYNFGPGVVWSGLATYVDSMAAIKKLVYDDRKYTLAQLNEALKADFA--GYDQ 650

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGS 627
           + A  +    KYGND D  D I+A+L+     E  KY+       + G+ ++S + P G 
Sbjct: 651 ILADCL-AAPKYGNDDDYADMIAADLVHFTETEHRKYKT-LYSVLSHGTLSISNNTPFGQ 708

Query: 628 VVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPAT 687
           ++GA+ +GR A   L+D G+SP  G D +GPTA++KSVSK+ N  ++ G + N K     
Sbjct: 709 LLGASANGRRAWMPLSD-GISPTQGADYKGPTAIIKSVSKMANDNMNIGMVHNFKLMSGL 767

Query: 688 LEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
           L+   G   L   +R    L    +QFN ++ + L +AQ+ P+ Y  LVVRVAGYSAFFV
Sbjct: 768 LDTPEGENGLITLIRTACMLGNGEMQFNYLDNELLLDAQKHPEKYRDLVVRVAGYSAFFV 827

Query: 748 ELSKEIQDDIIRRT 761
           EL K++QD+II RT
Sbjct: 828 ELCKDVQDEIISRT 841



>ref|YP_065559.1| Pyruvate formate-lyase 2 [Desulfotalea psychrophila LSv54]
 emb|CAG36552.1| Pyruvate formate-lyase 2 [Desulfotalea psychrophila LSv54]
          Length = 846

 Score =  416 bits (1069), Expect = e-114
 Identities = 270/794 (34%), Positives = 417/794 (52%), Gaps = 45/794 (5%)

Query: 2   TNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDE 61
           T+R  +LK     +   I+  RA   T   ++  G P  + R K+  Y  E   + I+D 
Sbjct: 59  TDRHIKLKKKFLTHVPTITTHRARAITKIAQENPGLPKAILRGKSFKYCCETAPLVIQDN 118

Query: 62  ELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWEK 121
           ELI G+    PRAG  SP++   W+  ELD   TRPQD F ISEEDK+I REELFP+WE 
Sbjct: 119 ELIVGSPCGAPRAGAFSPDIAWRWVKDELDTIGTRPQDPFFISEEDKKIMREELFPFWEG 178

Query: 122 RSMKDFINGQMTD----EVKAATNTQIFSINQT----DKGQGHIIIDYPRLLNHGLGELV 173
           RS+ ++   Q  +    E+   +     S + T    D   G+ +I    L+  G+ ++V
Sbjct: 179 RSIDEYCEQQYREAGMWELSGESYVTDCSYHATNGGGDSNPGYDVI----LMKKGMLDIV 234

Query: 174 AQMQQHCQQ----QPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREE 225
            + Q+   +     P++    +FY++ +   E    +  R ++ A  +AA+  D QR+ E
Sbjct: 235 RESQEKLAELDYENPDDMDKIYFYKSLIDTAEGVMIYAKRLSDYAAQLAASEKDPQRKAE 294

Query: 226 LLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLT 285
           L  I+ ++     HKP+T+W+A Q  W +  +L  E N + +S+GR DQYM PFY+  + 
Sbjct: 295 LEKISAVNARVPAHKPETYWEAIQAVWTVESLLIVEENQTGMSIGRVDQYMYPFYKADIE 354

Query: 286 QG---EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVN 342
            G   E  AF  +L   L VKC++++ + S  ++++FAG+       LGG+T  G  A N
Sbjct: 355 AGRMTEYEAF--DLSGCLLVKCSEMMWITSEDASKFFAGYQPFVNMCLGGVTREGLDATN 412

Query: 343 VLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFL 402
            L++L +DA + V++ QP++  R +      +L K  + IR G G P I  D+  +   L
Sbjct: 413 DLTYLLMDAVRHVKVYQPSVSTRVHNQSPQKYLKKIVDVIRAGMGFPAIHFDDAHIKIML 472

Query: 403 NRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN----------EG 452
            +G S+ED+RDY ++GCVE    GR Y     A       +E+ L+              
Sbjct: 473 AKGCSIEDSRDYCLMGCVEPQKSGRLYQWTSTAYTQWPICIEMALNHGVPLWYGKQVCPD 532

Query: 453 NAAL----TYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR 508
             AL    TYE     ++ +I +       G+ I    HRD AP PL+S     C+E G+
Sbjct: 533 LGALESFDTYEKFDAAVKEQIKYVTKWTSVGTVISQRIHRDLAPKPLMSMMYEGCMESGK 592

Query: 509 DITDGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEK 567
           D++ GGA YNF  GV   G+A  +DS+ A+K +VF+ ++ S  +L   LKA F   +  K
Sbjct: 593 DVSAGGAMYNFGPGVVWSGLATHADSMAAIKKLVFDDKKYSLTQLNEALKAEFKGYDQLK 652

Query: 568 VRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGS 627
                     K+GND D  D I  +L+    +E  K++       + G+ ++S + P G 
Sbjct: 653 ADCLAA---PKFGNDDDYADLIVNDLVNFTEREHRKFKTLYS-VLSHGTLSISNNTPFGQ 708

Query: 628 VVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPAT 687
           ++GA+ +GR A   L+DG +SP  G D +GPTA++KSVSK+    ++ G + N K     
Sbjct: 709 LLGASANGRDAWMPLSDG-ISPTQGADFKGPTAIIKSVSKMPTDSMNIGMVHNFKLMSGL 767

Query: 688 LEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFV 747
           L+   G   +   +R  + +    +QFN ++ DTL +AQ  P+ Y  LVVRVAGYSAFFV
Sbjct: 768 LDTPEGENGIITLIRTASMMGNGEMQFNYLDNDTLLDAQLHPEKYRDLVVRVAGYSAFFV 827

Query: 748 ELSKEIQDDIIRRT 761
           EL K++QD+II RT
Sbjct: 828 ELCKDVQDEIISRT 841



>ref|YP_356360.1| pyruvate-formate lyase [Pelobacter carbinolicus DSM 2380]
 gb|ABA88190.1| pyruvate-formate lyase [Pelobacter carbinolicus DSM 2380]
          Length = 808

 Score =  412 bits (1060), Expect = e-113
 Identities = 268/792 (33%), Positives = 412/792 (52%), Gaps = 39/792 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +  RI RLK A       I++ RAL +T   RQ  G P ILRRA A     E   + I+ 
Sbjct: 20  LPERIQRLKDAYLQVKPSIAIGRALAFTEVTRQNPGMPEILRRALAFKKACEDAPLLIQT 79

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G+   KPRAG  SP++   W+  ELD   TR QD F  SEEDK+I REE+FP+WE
Sbjct: 80  DELIVGHPCGKPRAGAFSPDIAWKWVRDELDTIGTRSQDPFVFSEEDKKIMREEIFPFWE 139

Query: 121 KRSMKDFINGQMTD----EVKAATNTQIFSINQTDKG----QGHIIIDYPRLLNHGLGEL 172
            RS+ +    Q  +    E  A       S +Q + G     G  +I + + ++    E 
Sbjct: 140 GRSLDEICETQYREAGLWEFAAEAFVSDLSYHQVNGGGDTCPGFDVILFTKGVSGIKAEA 199

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
            A + +     P++    +FY+AA+   E    +  R +  A+ +A    D +R+ EL  
Sbjct: 200 EAHLAKLSMDVPDDIDRIYFYKAAIQTCEGIVTYANRVSAYAKELAEKEQDPKRKAELEK 259

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQG- 287
           IAE++     + P +F +A Q  W +  +   E N + LSLGR DQY+ P Y+  +  G 
Sbjct: 260 IAEVNARVPANPPSSFQEALQSIWTIESLFVIEENQTGLSLGRLDQYVYPCYEADIKAGV 319

Query: 288 --EDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLS 345
             ED AF  EL+    +KC +++ L S  +A+YFAG+       +GG    G  A N L+
Sbjct: 320 IDEDQAF--ELMSCFIIKCAEMMWLTSELAAKYFAGYQPFINLCVGGQKREGGDATNDLT 377

Query: 346 FLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRG 405
           +L +D  + + + QP+L  R +      +L K  E ++ G G P    D+  +   L +G
Sbjct: 378 YLVMDVVRKLGVYQPSLACRIHNQSPQKYLQKIVEVVKAGLGFPACHFDDAHIKMMLRKG 437

Query: 406 VSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE--------------NE 451
              EDARDY ++GCVE    GR Y             +E  L+                +
Sbjct: 438 YDFEDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPVAIEFVLNRGVMKWHGTKQGIDTGD 497

Query: 452 GNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDIT 511
            +   TYE     ++ +I +   L   G+ I    HRD AP P++S F+  C+E G+D++
Sbjct: 498 LDQFATYEQFDAAVKEQIEYICKLSAVGTVISQRVHRDVAPKPMMSLFVEGCMETGKDVS 557

Query: 512 DGGARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEG-EKVR 569
            GGA  N   G+   G+A  +DS+ ++K +V++ ++ +  +    L AN+   EG E++R
Sbjct: 558 AGGAVLNHGPGLIFSGLATYADSMASIKKLVYDDKKYTLADFQKALDANW---EGYEQMR 614

Query: 570 ARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVV 629
              ++   KYGND D  D I+A+L+    K   +++       + G+ ++S + P+G + 
Sbjct: 615 QDCLDA-PKYGNDDDYADKIAADLVEFTEKACRQFK-MLYSTMSHGTLSISNNTPIGEIT 672

Query: 630 GATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLE 689
           GAT DGR A   L+D G+SP+ G D  GPTA++KSVSK+++  ++ G + N K     LE
Sbjct: 673 GATADGRLAFTPLSD-GISPVQGADKMGPTAIIKSVSKMNSESMNIGMVHNFKLMEGILE 731

Query: 690 GEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVEL 749
              G   L   LR  + L    +QF+ V+ + L++AQQ P++Y  L++RVAGYSAFFVEL
Sbjct: 732 TPEGEAGLITLLRTASILGNGQMQFSYVDNEVLKQAQQSPEEYRDLMIRVAGYSAFFVEL 791

Query: 750 SKEIQDDIIRRT 761
            KE+QD+II RT
Sbjct: 792 CKEVQDEIISRT 803



>ref|YP_051857.1| putative formate acetyltransferase [Erwinia carotovora subsp.
           atroseptica SCRI1043]
 emb|CAG76667.1| putative formate acetyltransferase [Erwinia carotovora subsp.
           atroseptica SCRI1043]
          Length = 834

 Score =  412 bits (1059), Expect = e-113
 Identities = 261/789 (33%), Positives = 413/789 (52%), Gaps = 33/789 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R+ RL+         IS+ RAL +T   +   G P IL RAK+     E   I I+D
Sbjct: 46  LTPRMQRLRAHYLEARPSISIYRALAFTEVAKNNPGLPSILLRAKSFRRACETAPILIQD 105

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           EELI G+   KPRAG  SP++   W+  ELD   TRPQD F ISEEDK+  REE+ P+W+
Sbjct: 106 EELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMSTRPQDPFQISEEDKKTIREEIAPFWQ 165

Query: 121 KRSMKDFINGQMTD----EVKAATNTQIFSINQTDKG----QGHIIIDYPRLLNHGLGEL 172
            RS+ +    Q  +    E    T     S +Q + G     G+ ++ + + +     + 
Sbjct: 166 GRSLDEVCEAQYREAGLWEFSGETFVSDLSYHQINGGGDTCPGYDVLLFTKGMKGIKADA 225

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
            A++ +   + P +    +FY+AA+   +    +  R A  A   AA   DA RR ELL 
Sbjct: 226 QAKLAELGMEDPAHIDRIYFYKAAIETCDGVMAYASRIAAHAREQAAQENDALRRAELLL 285

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE 288
           IA+++ +   + P+T  +A Q  W +  + + E N + +SLGR DQY  P Y+  +  G 
Sbjct: 286 IADVNENVPANPPKTLQEALQSIWTLESLFEIEENQTGISLGRVDQYCYPMYEADIQSGR 345

Query: 289 -DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFL 347
                  ELL+   +KC +++ + S S A+YFAG+       +GG   +G  A N L++L
Sbjct: 346 LTREQALELLQMFIIKCAELMWMSSESGAKYFAGYQPFINLTVGGQKRSGGDACNDLTYL 405

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
            +DA + V++ QP+L  R +      ++ K  + ++ G G P    D+  +   L +G  
Sbjct: 406 IMDAVRFVKVYQPSLACRIHNQSPHEYMEKIVDVVKSGMGFPACHFDDSHIKMMLRKGFD 465

Query: 408 LEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHE--------------NEGN 453
            +DARDY ++GCVE    GR Y             +E  L+                E +
Sbjct: 466 FDDARDYCLMGCVEPQKSGRIYQWTSTGYTQWPIAIEFALNRGRMILFDRVQGVDTGELS 525

Query: 454 AALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDG 513
           +  T+E     ++ +I+H I L   G+ I    HRD AP PL+S  +  C+EKG+D+  G
Sbjct: 526 SLDTFEAFDRAVKTQIAHIIRLSAIGTVISQRVHRDIAPKPLMSLLVEGCMEKGQDVAAG 585

Query: 514 GARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARL 572
           GA  N   G+   G+A   DS+ A++ +V+E ++ + +++   L ANF+   G ++  R 
Sbjct: 586 GALINHGPGLIFSGLATYVDSMMAIRKLVYEDRKYTLEQMRDALLANFS---GYEMLHRE 642

Query: 573 INRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGAT 632
                K+GND + VD ++ ++     +E  +Y+      F+ G+ ++S + P+G++  A+
Sbjct: 643 CLNAPKFGNDDNAVDPLARDITEWTERECRQYK-MLYSTFSHGTLSISNNTPIGALTAAS 701

Query: 633 PDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEA 692
            +GR A   L+D G+SP  G D +GPTA +KSVSK++   ++ G + N KF    L+   
Sbjct: 702 ANGRLAWAPLSD-GISPTQGADKKGPTASIKSVSKMNVESMNIGMVHNFKFLKGMLDTPE 760

Query: 693 GLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKE 752
           G   L   LR  + L    +QF+ V+ + LR+AQQ P+ Y  L+VRVAGYSA+FVEL KE
Sbjct: 761 GRNGLITLLRTSSILGNGQMQFSYVDDEVLRKAQQAPEKYRDLIVRVAGYSAYFVELCKE 820

Query: 753 IQDDIIRRT 761
           +QD+II RT
Sbjct: 821 VQDEIISRT 829



>ref|YP_064352.1| formate C-acetyltransferase [Desulfotalea psychrophila LSv54]
 emb|CAG35345.1| probable formate C-acetyltransferase [Desulfotalea psychrophila
           LSv54]
          Length = 783

 Score =  410 bits (1055), Expect = e-112
 Identities = 268/791 (33%), Positives = 411/791 (51%), Gaps = 38/791 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGE-PVILRRAKATAYILEHVEISIR 59
           M +RI RL+   F+    IS+ERALL T  +++  G+ P+ + RA    ++ +H  + I 
Sbjct: 1   MNSRIERLRQKSFSTQASISIERALLETEFYKENSGKYPLPILRALCFQHLCQHKTLYIG 60

Query: 60  DEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYW 119
           D+ELI G R   P+A    PE+  +   ++L     RP   + +S+ED   Y EE+ PYW
Sbjct: 61  DDELIVGERGPSPKAVPTFPELTCH-SAEDLHILNDRPMTNYRLSDEDINRYEEEVIPYW 119

Query: 120 EKRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIIDYPRLLNHGLGELVAQMQQH 179
           + RSM+D I     +E + A    +F+     +  GH  +D   +   G+ +  A++   
Sbjct: 120 QGRSMRDRIFKNAPEEWRQAYQAGLFTEFMEQRAPGHTALD-GTIYREGMLDFKARIAGR 178

Query: 180 CQQ---------QPENHFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLTIA 230
             +           +    QA  +   A+     R+AELAE MA    + +RR+ELL IA
Sbjct: 179 IARLDFLTDPRAADQREELQAMDISCNAAIIFAKRHAELAERMADK-EEGERRQELLEIA 237

Query: 231 EISRHNAQHKPQTFWQACQLFWYMNIILQYESNA-SSLSLGRFDQYMLPFYQTSLTQGE- 288
            I R    H P+T  +A Q++W++++    E N   +++ G  D ++ PFY+  L  G  
Sbjct: 238 RICRWVPAHAPRTMHEAIQMYWFVHLGTITELNGWDAMTPGHLDHHLHPFYENDLASGIL 297

Query: 289 DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTAL-LGGLTENGRSAVNVLSFL 347
           +    KEL+  LW+K N+             +G    +T + LGGL  NG+   N +S++
Sbjct: 298 NREGAKELMACLWIKINNHTAPPKVGVTAKESGTYNDFTQINLGGLQRNGQDGSNEISYI 357

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
            L+    + L QP   +  +    T  L    E +R G G P  FN + VV   +  G S
Sbjct: 358 ALEVSDELHLLQPQPSIHLSQQSPTRLLASACEVVRKGYGYPSFFNADGVVTQLVRAGKS 417

Query: 408 LEDARDYSVVGCVELSIPGR-TYGLHDIAMFNLLKVMEICLHEN--------------EG 452
           LEDAR+    GC+E    G+  Y L      N+ K++EI LH                E 
Sbjct: 418 LEDAREGGTSGCIETGAFGKEAYIL--TGYLNVPKILEITLHNGIDPLSGIRVGLETGEA 475

Query: 453 NAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITD 512
           +   T+  L +    +++H I L V  +N  +  +  ++P P LS  I DC+EKGRD  D
Sbjct: 476 SFFQTFSALYKAFEQQLNHIIQLKVRMNNYIERMYGKYSPAPFLSVVIHDCIEKGRDYYD 535

Query: 513 GGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGEKVRARL 572
            G RYN + +Q  GI  ++DSL ALK  VFE + LS ++++  L +NF   E  ++RA L
Sbjct: 536 AGPRYNSNYIQCCGIGTVTDSLSALKTHVFEGE-LSMEKMVKTLASNFQGEE--ELRADL 592

Query: 573 INRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGAT 632
           +N    YGN+ D  D+I   +     + ++  +N +GG +     + + HV  G ++GA+
Sbjct: 593 LNNTPFYGNNDDLADDIMQRVYHSLFQGIDGQKNTKGGEYHLNMLSTTCHVYFGKMLGAS 652

Query: 633 PDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEA 692
            +GR AG   +DG  SP  G D QGPTAV+KS+ K+D    S GTLLN +F PA L+ E+
Sbjct: 653 ANGRLAGLPTSDG-TSPSQGADLQGPTAVIKSLGKMDQ-YKSGGTLLNQRFLPAALKDES 710

Query: 693 GLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSKE 752
            L+ L   +R +  L   HIQFNVV++ TL++AQQ P  Y  L+VRVAGYS +FV+L + 
Sbjct: 711 DLKNLGHLIRTYFSLGGHHIQFNVVDSKTLKKAQQHPDQYKNLLVRVAGYSDYFVDLDRA 770

Query: 753 IQDDIIRRTAH 763
            Q++II RT H
Sbjct: 771 HQEEIISRTGH 781



>ref|YP_521239.1| pyruvate-formate lyase [Desulfitobacterium hafniense Y51]
 dbj|BAE86795.1| pyruvate-formate lyase [Desulfitobacterium hafniense Y51]
          Length = 823

 Score =  409 bits (1050), Expect = e-112
 Identities = 265/790 (33%), Positives = 409/790 (51%), Gaps = 35/790 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R++ L+T        +S++RA  +T   R+  G P IL RAK      E   + I+ 
Sbjct: 35  LTPRLNNLRTVYLQAKPSVSIDRARAFTEVTRENPGLPKILLRAKCFRRACETAPLLIQK 94

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G+   KPRAG  SP++   W+  ELD   TRPQD F ISEEDKRI REE+FP+WE
Sbjct: 95  DELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMATRPQDPFQISEEDKRILREEIFPFWE 154

Query: 121 KRSMKDFINGQMTDEVKAATNTQIF----SINQT----DKGQGHIIIDYPRLLNHGLGEL 172
            +S+ +    Q  D    + + + F    S +Q     D   G+ +I   + +     E 
Sbjct: 155 GKSVDEICQKQYEDAGIWSFSGESFVSDLSYHQINGGGDTAPGYDVILIKKGIKGVRQEA 214

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
             ++ +   + PE+    +FY+A +   +    +  R ++ A   A    D+ R++EL  
Sbjct: 215 EDRLSRLSMENPEDIDKIYFYKAEIETCDGILAYARRLSDYARESADREVDSVRKQELHK 274

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE 288
           IA++      + P+TF +A Q  W +  +   E N + +SLGR DQY+ P ++  +  G 
Sbjct: 275 IADVLTWVPANPPRTFHEALQSIWTLESLFVVEENQTGISLGRLDQYIYPMFKADMDAGR 334

Query: 289 -DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFL 347
            +     EL+    +KC++++ L S   A+YFAG+       +GG    G  A N L++L
Sbjct: 335 LNKLEAFELMSCFLIKCSEVMWLSSEQGAKYFAGYQPFINCTVGGQKRTGGDATNELTYL 394

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
            +DA +  ++ QP+L  R +      +L K  E ++ G G P    D+  +   L +G S
Sbjct: 395 IMDAVRFTKMYQPSLACRIHNQSPQRYLKKIVEVVKAGLGFPACHFDDSHIKMMLAKGFS 454

Query: 408 LEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN--------EG------N 453
           +ED+RDY ++GCVE    G  Y             +E  L+          EG      +
Sbjct: 455 IEDSRDYCLMGCVEPQKSGGIYQWTSTGYTQWPIAIEFVLNRGVMKWRGTMEGLDTGDLD 514

Query: 454 AALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDG 513
              TYE      + +I + I L   G+ I    H++  P PL+S  +  C+EKG D+T G
Sbjct: 515 NFKTYEEFDAACKQQIENIIRLSAIGTIISQRVHKELVPKPLMSLLVEGCMEKGTDVTSG 574

Query: 514 GARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEG-EKVRAR 571
           GAR NF  G+   G+   +DS+ A+K +VFE+++ +  ++   L ANF   EG E +R  
Sbjct: 575 GARINFGPGLIFSGLGTYADSMAAIKKLVFEEKKYTLKQIRDALNANF---EGYEALRTD 631

Query: 572 LINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGA 631
            +N   KYGND D  D I+++L+  + + V         +FT G+ ++S + P+G + GA
Sbjct: 632 CLNA-PKYGNDDDYADLIASDLI-VWTERVHNSFKMLFSHFTHGTLSISNNTPIGEITGA 689

Query: 632 TPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGE 691
           TP+GR A   L+D G+SP  G D  GPTA++KSVSKL    ++ G + N K     LE  
Sbjct: 690 TPNGRLAWTPLSD-GISPTQGADKFGPTAIIKSVSKLSVESMNIGMVHNFKLLRGILETP 748

Query: 692 AGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSK 751
            G   L   LR  + L    +QF+ V+ + L+ AQ  P  Y  L++RVAGYSA+FVEL K
Sbjct: 749 EGENGLITLLRTASILGNGQMQFSYVDNEVLKRAQIEPDKYRDLIIRVAGYSAYFVELCK 808

Query: 752 EIQDDIIRRT 761
           E+QD+II RT
Sbjct: 809 EVQDEIISRT 818



>ref|ZP_01371837.1| pyruvate formate-lyase, PFL [Desulfitobacterium hafniense DCB-2]
 gb|EAT50579.1| pyruvate formate-lyase, PFL [Desulfitobacterium hafniense DCB-2]
          Length = 848

 Score =  409 bits (1050), Expect = e-112
 Identities = 265/790 (33%), Positives = 409/790 (51%), Gaps = 35/790 (4%)

Query: 1   MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRD 60
           +T R++ L+T        +S++RA  +T   R+  G P IL RAK      E   + I+ 
Sbjct: 60  LTPRLNNLRTVYLQAKPSVSIDRARAFTEVTRENPGLPKILLRAKCFRRACETAPLLIQK 119

Query: 61  EELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFAISEEDKRIYREELFPYWE 120
           +ELI G+   KPRAG  SP++   W+  ELD   TRPQD F ISEEDKRI REE+FP+WE
Sbjct: 120 DELIVGHPCGKPRAGAFSPDIAWRWVRDELDTMATRPQDPFQISEEDKRILREEIFPFWE 179

Query: 121 KRSMKDFINGQMTDEVKAATNTQIF----SINQT----DKGQGHIIIDYPRLLNHGLGEL 172
            +S+ +    Q  D    + + + F    S +Q     D   G+ +I   + +     E 
Sbjct: 180 GKSVDEICQKQYEDAGIWSFSGESFVSDLSYHQINGGGDTAPGYDVILIKKGIKGVRQEA 239

Query: 173 VAQMQQHCQQQPEN----HFYQAALLLLEASQKHILRYAELAETMAANCTDAQRREELLT 228
             ++ +   + PE+    +FY+A +   +    +  R ++ A   A    D+ R++EL  
Sbjct: 240 EDRLSRLSMENPEDIDKIYFYKAEIEACDGILAYARRLSDYARESADREVDSVRKQELHK 299

Query: 229 IAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQTSLTQGE 288
           IA++      + P+TF +A Q  W +  +   E N + +SLGR DQY+ P ++  +  G 
Sbjct: 300 IADVLTWVPANPPRTFHEALQSIWTLESLFVVEENQTGISLGRLDQYIYPMFKADMDAGR 359

Query: 289 -DAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLTENGRSAVNVLSFL 347
            +     EL+    +KC++++ L S   A+YFAG+       +GG    G  A N L++L
Sbjct: 360 LNKLEAFELMSCFLIKCSEVMWLSSEQGAKYFAGYQPFINCTVGGQKRTGGDATNELTYL 419

Query: 348 CLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIFNDEVVVPAFLNRGVS 407
            +DA +  ++ QP+L  R +      +L K  E ++ G G P    D+  +   L +G S
Sbjct: 420 IMDAVRFTKMYQPSLACRIHNQSPQRYLKKIVEVVKAGLGFPACHFDDSHIKMMLAKGFS 479

Query: 408 LEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN--------EG------N 453
           +ED+RDY ++GCVE    G  Y             +E  L+          EG      +
Sbjct: 480 IEDSRDYCLMGCVEPQKSGGIYQWTSTGYTQWPIAIEFVLNRGVMKWRGTMEGLDTGDLD 539

Query: 454 AALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGRDITDG 513
              TYE      + +I + I L   G+ I    H++  P PL+S  +  C+EKG D+T G
Sbjct: 540 NFKTYEEFDAACKQQIENIIRLSAIGTIISQRVHKELVPKPLMSLLVEGCMEKGTDVTSG 599

Query: 514 GARYNFS-GVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEG-EKVRAR 571
           GAR NF  G+   G+   +DS+ A+K +VFE+++ +  ++   L ANF   EG E +R  
Sbjct: 600 GARINFGPGLIFSGLGTYADSMAAIKKLVFEEKKYTLKQIRDALNANF---EGYEALRTD 656

Query: 572 LINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGA 631
            +N   KYGND D  D I+++L+  + + V         +FT G+ ++S + P+G + GA
Sbjct: 657 CLNA-PKYGNDDDYADLIASDLI-IWTERVHNSFKMLFSHFTHGTLSISNNTPIGEITGA 714

Query: 632 TPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGE 691
           TP+GR A   L+D G+SP  G D  GPTA++KSVSKL    ++ G + N K     LE  
Sbjct: 715 TPNGRLAWTPLSD-GISPTQGADKFGPTAIIKSVSKLSVESMNIGMVHNFKLLRGILETP 773

Query: 692 AGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVAGYSAFFVELSK 751
            G   L   LR  + L    +QF+ V+ + L+ AQ  P  Y  L++RVAGYSA+FVEL K
Sbjct: 774 EGENGLITLLRTASILGNGQMQFSYVDNEVLKRAQIEPDKYRDLIIRVAGYSAYFVELCK 833

Query: 752 EIQDDIIRRT 761
           E+QD+II RT
Sbjct: 834 EVQDEIISRT 843



>ref|YP_389528.1| Formate C-acetyltransferase [Desulfovibrio desulfuricans G20]
 gb|ABB39833.1| Formate C-acetyltransferase [Desulfovibrio desulfuricans G20]
          Length = 808

 Score =  407 bits (1046), Expect = e-111
 Identities = 273/796 (34%), Positives = 407/796 (51%), Gaps = 45/796 (5%)

Query: 1   MTNRISRLKTALFANTREISLERALLYT