BLAST Search Results

Blast performed on February-3-2012 BLASTP 2.2.24+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: nr_env 20,512,688 sequences; 6,167,035,527 total letters Query= EG10573 mcrA Length=277 Score E Sequences producing significant alignments: (Bits) Value ref|NP_415677.1| e14 prophage; 5-methylcytosine-specific restric... 574 7e-162 gb|EGA03413.1| e14 prophage; 5-methylcytosine-specific restricti... 543 1e-152 ref|YP_001564178.1| HNH endonuclease [Delftia acidovorans SPH-1]... 131 1e-28 ref|YP_002874288.1| putative 5-methylcytosine-specific restricti... 128 1e-27 ref|ZP_07777116.1| HNH endonuclease [Pseudomonas fluorescens WH6... 126 3e-27 gb|ECO37670.1| hypothetical protein GOS_5707677 [marine metagenome] 125 5e-27 ref|YP_065769.1| 5-methylcytosine-specific restriction enzyme A ... 124 2e-26 ref|YP_412292.1| HNH nuclease [Nitrosospira multiformis ATCC 251... 122 7e-26 ref|YP_856158.1| 5-methylcytosine-specific restriction protein A... 120 2e-25 gb|EDA49155.1| hypothetical protein GOS_1991726 [marine metagenome] 120 3e-25 ref|YP_001584201.1| HNH endonuclease [Burkholderia multivorans A... 119 4e-25 ref|ZP_03583033.1| HNH nuclease [Burkholderia multivorans CGD1] ... 119 6e-25 gb|EBZ73193.1| hypothetical protein GOS_4171158 [marine metagenome] 119 7e-25 gb|ECE40492.1| hypothetical protein GOS_3100346 [marine metagenome] 118 8e-25 ref|YP_002234131.1| putative restriction endonuclease [Burkholde... 117 2e-24 ref|YP_001359725.1| 5-methylcytosine-specific restriction enzyme... 115 1e-23 ref|ZP_01226771.1| putative 5-methylcytosine-specific restrictio... 114 1e-23 gb|EGD03908.1| 5-methylcytosine-specific restriction enzyme A [B... 114 1e-23 ref|ZP_02373776.1| HNH endonuclease [Burkholderia thailandensis ... 110 4e-22 ref|YP_350025.1| HNH endonuclease [Pseudomonas fluorescens Pf0-1... 104 2e-20 ref|ZP_04240702.1| HNH nuclease [Bacillus cereus Rock1-15] >gb|E... 103 3e-20 ref|ZP_02890149.1| HNH endonuclease [Burkholderia ambifaria IOP4... 100 2e-19 ref|ZP_04111523.1| HNH nuclease [Bacillus thuringiensis serovar ... 100 2e-19 ref|ZP_04081906.1| HNH nuclease [Bacillus thuringiensis serovar ... 100 2e-19 ref|YP_003259158.1| HNH endonuclease [Pectobacterium wasabiae WP... 99.8 4e-19 ref|ZP_06898418.1| 5-methylcytosine-specific restriction enzyme ... 98.6 9e-19 ref|YP_003332055.1| HNH endonuclease [Dickeya dadantii Ech586] >... 98.2 1e-18 ref|ZP_04309075.1| HNH nuclease [Bacillus cereus 172560W] >gb|EE... 97.8 2e-18 gb|ECQ33615.1| hypothetical protein GOS_6056978 [marine metagenome] 97.4 2e-18 ref|YP_387711.1| HNH nuclease [Desulfovibrio desulfuricans subsp... 97.4 2e-18 gb|EBI36964.1| hypothetical protein GOS_9104437 [marine metagenome] 97.4 2e-18 ref|ZP_06157518.1| HNH nuclease [Photobacterium damselae subsp. ... 97.1 3e-18 ref|ZP_07043201.1| HNH endonuclease [Comamonas testosteroni S44]... 97.1 3e-18 gb|ECF76608.1| hypothetical protein GOS_4933757 [marine metagenome] 95.9 7e-18 ref|YP_003726057.1| HNH endonuclease [Methanohalobium evestigatu... 95.1 1e-17 ref|ZP_03781850.1| hypothetical protein RUMHYD_01286 [Blautia hy... 94.4 2e-17 ref|YP_001023049.1| hypothetical protein Mpe_B0033 [Methylibium ... 94.4 2e-17 ref|ZP_03029796.1| HNH endonuclease [Escherichia coli B7A] >gb|E... 94.0 2e-17 ref|ZP_07151494.1| HNH endonuclease domain protein [Escherichia ... 94.0 3e-17 ref|ZP_08129831.1| 5-methylcytosine-specific restriction enzyme ... 93.6 3e-17 ref|ZP_05920085.1| 5-methylcytosine-specific restriction enzyme ... 92.8 5e-17 gb|EDA78595.1| hypothetical protein GOS_1937529 [marine metagenome] 92.0 8e-17 ref|YP_004189288.1| HNH endonuclease [Vibrio vulnificus MO6-24/O... 91.7 1e-16 ref|ZP_00989258.1| putative restriction endonuclease [Vibrio spl... 91.3 2e-16 ref|YP_001528806.1| HNH endonuclease [Desulfococcus oleovorans H... 90.9 2e-16 ref|ZP_02432833.1| hypothetical protein CLOSCI_03091 [Clostridiu... 90.9 2e-16 gb|ECT50358.1| hypothetical protein GOS_5713549 [marine metagenome] 90.9 2e-16 ref|YP_001339470.1| HNH endonuclease [Marinomonas sp. MWYL1] >gb... 90.9 2e-16 ref|YP_001129610.1| HNH endonuclease [Chlorobium phaeovibrioides... 90.5 3e-16 gb|EBQ48256.1| hypothetical protein GOS_7744649 [marine metagenome] 90.5 3e-16 ref|ZP_04634188.1| Restriction endonuclease [Yersinia frederikse... 90.1 3e-16 ref|ZP_01667048.1| HNH endonuclease [Thermosinus carboxydivorans... 89.7 4e-16 ref|YP_002139592.1| HNH endonuclease [Geobacter bemidjiensis Bem... 89.7 5e-16 ref|ZP_08559105.1| HNH endonuclease [Halorhabdus tiamatea SARL4B... 89.4 7e-16 emb|CBL27586.1| Restriction endonuclease [Ruminococcus torques L... 89.0 7e-16 ref|YP_003812225.1| probable endonuclease [gamma proteobacterium... 89.0 7e-16 ref|ZP_01063162.1| HNH endonuclease [Vibrio sp. MED222] >gb|EAQ5... 89.0 8e-16 ref|ZP_05430896.1| HNH endonuclease [Clostridium thermocellum DS... 89.0 8e-16 ref|YP_003007474.1| HNH nuclease [Aggregatibacter aphrophilus NJ... 88.6 1e-15 ref|YP_004378892.1| putative restriction endonuclease [Pseudomon... 87.8 2e-15 gb|ECM81520.1| hypothetical protein GOS_4910044 [marine metagenome] 87.8 2e-15 ref|YP_004307224.1| HNH endonuclease [Clostridium lentocellum DS... 87.8 2e-15 gb|ECB05675.1| hypothetical protein GOS_5878671 [marine metagenome] 87.4 3e-15 ref|ZP_01741593.1| HNH nuclease [Rhodobacterales bacterium HTCC2... 87.4 3e-15 ref|ZP_08167033.1| HNH endonuclease domain protein [Turicibacter... 87.0 3e-15 ref|ZP_06181860.1| hypothetical protein VMC_32900 [Vibrio algino... 86.3 5e-15 ref|ZP_04220300.1| restriction endonuclease [Bacillus cereus Roc... 86.3 5e-15 ref|YP_004156661.1| hnh nuclease [Variovorax paradoxus EPS] >gb|... 85.9 6e-15 ref|ZP_03991369.1| conserved hypothetical protein [Oribacterium ... 85.5 7e-15 gb|ECK58534.1| hypothetical protein GOS_3293689 [marine metagenome] 85.5 8e-15 ref|YP_579285.1| HNH endonuclease [Psychrobacter cryohalolentis ... 85.5 9e-15 ref|YP_004425314.1| HNH nuclease [Alteromonas macleodii str. 'De... 85.1 1e-14 gb|EDI01692.1| hypothetical protein GOS_502793 [marine metagenome] 85.1 1e-14 gb|ECI86970.1| hypothetical protein GOS_3101369 [marine metagenome] 84.7 1e-14 gb|EBG21407.1| hypothetical protein GOS_9471027 [marine metagenome] 84.3 2e-14 ref|ZP_03942694.1| possible HNH endonuclease [Lactobacillus buch... 84.3 2e-14 ref|ZP_06675235.1| putative restriction endonuclease [Enterococc... 84.3 2e-14 ref|ZP_01957981.1| HNH endonuclease [Vibrio cholerae MZO-3] >gb|... 84.3 2e-14 gb|EBK97490.1| hypothetical protein GOS_8644480 [marine metagenome] 82.8 6e-14 ref|ZP_04075199.1| restriction endonuclease [Bacillus thuringien... 82.8 6e-14 ref|ZP_08244461.1| HNH endonuclease domain protein [Streptococcu... 82.4 7e-14 ref|ZP_05104468.1| HNH endonuclease domain protein [Methylophaga... 82.0 9e-14 gb|ECN42405.1| hypothetical protein GOS_5991417 [marine metagenome] 82.0 9e-14 gb|ECT90871.1| hypothetical protein GOS_4098770 [marine metagenome] 81.6 1e-13 ref|ZP_04146973.1| restriction endonuclease [Bacillus thuringien... 81.6 1e-13 ref|YP_003967142.1| HNH endonuclease [Ilyobacter polytropus DSM ... 81.3 2e-13 ref|ZP_05096021.1| HNH endonuclease domain protein [marine gamma... 80.5 2e-13 ref|YP_751179.1| HNH endonuclease [Shewanella frigidimarina NCIM... 80.1 4e-13 ref|YP_300163.1| restriction endonuclease [Staphylococcus saprop... 79.7 4e-13 ref|ZP_04177672.1| restriction endonuclease [Bacillus cereus AH1... 79.3 6e-13 ref|YP_003406048.1| HNH endonuclease [Haloterrigena turkmenica D... 79.0 7e-13 ref|ZP_05658159.1| HNH endonuclease [Enterococcus faecium 1,230,... 79.0 9e-13 ref|ZP_05674502.1| LOW QUALITY PROTEIN: restriction endonuclease... 78.6 1e-12 ref|YP_761227.1| hypothetical protein HNE_2533 [Hyphomonas neptu... 78.6 1e-12 ref|ZP_04682599.1| Hypothetical protein OINT_2001093 [Ochrobactr... 77.8 2e-12 gb|EBP41480.1| hypothetical protein GOS_7915120 [marine metagenome] 77.4 2e-12 ref|YP_003563225.1| hypothetical protein BMQ_2769 [Bacillus mega... 74.3 2e-11 ref|YP_003597996.1| hypothetical protein BMD_2805 [Bacillus mega... 73.9 3e-11 ref|YP_004069992.1| restriction endonuclease-like protein [Pseud... 72.4 7e-11 ref|ZP_02150571.1| putative restriction endonuclease [Phaeobacte... 71.6 1e-10 ref|ZP_06918687.1| conserved hypothetical protein [Streptomyces ... 70.5 3e-10 ref|YP_003620463.1| putative restriction endonuclease [Leuconost... 69.7 4e-10 ref|ZP_08481963.1| putative restriction endonuclease [Leuconosto... 69.7 5e-10 ref|YP_001817971.1| HNH endonuclease [Opitutus terrae PB90-1] >g... 69.3 7e-10 gb|ECH87844.1| hypothetical protein GOS_3518611 [marine metagenome] 65.5 1e-08 ref|ZP_02076561.1| hypothetical protein EUBDOL_00350 [Eubacteriu... 65.1 1e-08 ref|YP_003518255.1| HNH endonuclease typeIV restriction enzyme [... 65.1 1e-08 ref|YP_350356.1| HNH endonuclease [Pseudomonas fluorescens Pf0-1... 64.7 2e-08 ref|NP_628792.1| hypothetical protein SCO4631 [Streptomyces coel... 64.3 2e-08 gb|EEE73045.1| predicted protein [Populus trichocarpa] 63.5 4e-08 ref|ZP_02428247.1| hypothetical protein CLORAM_01640 [Clostridiu... 63.5 4e-08 ref|ZP_04114617.1| 5-methylcytosine-specific restriction enzyme ... 60.8 2e-07 ref|ZP_04203007.1| 5-methylcytosine-specific restriction enzyme ... 60.8 2e-07 ref|YP_724534.1| restriction endonuclease [Ralstonia eutropha H1... 60.5 3e-07 ref|ZP_00990414.1| putative restriction endonuclease [Vibrio spl... 60.1 4e-07 ref|ZP_04248670.1| hypothetical protein bcere0017_56020 [Bacillu... 60.1 4e-07 ref|ZP_04242774.1| 5-methylcytosine-specific restriction enzyme ... 59.7 5e-07 gb|EDC34285.1| hypothetical protein GOS_1492930 [marine metagenome] 59.3 7e-07 ref|ZP_07388900.1| conserved hypothetical protein [Paenibacillus... 58.9 9e-07 ref|ZP_06249276.1| transcriptional regulator, XRE family [Clostr... 58.5 1e-06 ref|ZP_06912007.1| predicted protein [Streptomyces pristinaespir... 58.5 1e-06 ref|YP_003313094.1| HNH endonuclease [Sanguibacter keddieii DSM ... 58.2 1e-06 ref|ZP_01001666.1| e14 prophage-like protein [Oceanicola batsens... 58.2 2e-06 ref|ZP_01619437.1| hypothetical protein L8106_06379 [Lyngbya sp.... 57.8 2e-06 ref|YP_004152990.1| hnh endonuclease [Variovorax paradoxus EPS] ... 57.4 2e-06 gb|EBN30596.1| hypothetical protein GOS_8268251 [marine metagenome] 57.0 4e-06 ref|ZP_06407844.1| 5-methylcytosine-specific restriction enzyme ... 56.2 6e-06 ref|ZP_05346026.1| product McrA [Bryantella formatexigens DSM 14... 55.8 6e-06 ref|ZP_05233454.1| conserved hypothetical protein [Listeria mono... 55.5 9e-06 ref|YP_002773045.1| hypothetical protein BBR47_35640 [Brevibacil... 55.5 1e-05 ref|ZP_01040994.1| 5-methylcytosine-specific restriction enzyme ... 55.1 1e-05 ref|NP_831911.1| 5-methylcytosine-specific restriction enzyme A ... 55.1 1e-05 ref|YP_012937.1| hypothetical protein LMOf2365_0328 [Listeria mo... 54.7 1e-05 ref|ZP_08605680.1| hypothetical protein HMPREF0994_01686 [Lachno... 54.7 2e-05 ref|YP_002886182.1| HNH endonuclease [Exiguobacterium sp. AT1b] ... 54.7 2e-05 gb|EFR95085.1| putative recombinase [Listeria innocua FSL J1-023] 54.7 2e-05 ref|ZP_07839158.1| HNH endonuclease [Eubacterium cellulosolvens ... 54.3 2e-05 ref|YP_004332990.1| HNH endonuclease [Pseudonocardia dioxanivora... 53.9 3e-05 ref|ZP_06824551.1| HNH endonuclease [Streptomyces sp. SPB74] >gb... 53.9 3e-05 ref|NP_635336.1| 5-methylcytosine-specific restriction enzyme A ... 53.5 4e-05 ref|ZP_04957665.1| HNH endonuclease domain protein [gamma proteo... 53.1 5e-05 ref|YP_001420334.1| hypothetical protein RBAM_007180 [Bacillus a... 52.0 1e-04 gb|EDG66067.1| hypothetical protein GOS_743329 [marine metagenome] 52.0 1e-04 ref|ZP_03016326.1| hypothetical protein BACINT_03931 [Bacteroide... 52.0 1e-04 ref|YP_001817436.1| restriction endonuclease-like protein [Opitu... 51.6 1e-04 ref|ZP_06707761.1| HNH endonuclease domain-containing protein [S... 51.6 1e-04 ref|ZP_05273201.1| 5-methylcytosine-specific restriction enzyme ... 51.2 2e-04 ref|ZP_02212388.1| hypothetical protein CLOBAR_02005 [Clostridiu... 50.8 2e-04 ref|YP_368267.1| hypothetical protein Bcep18194_A4026 [Burkholde... 50.8 3e-04 ref|ZP_04068325.1| HNH endonuclease [Bacillus thuringiensis IBL ... 50.8 3e-04 ref|ZP_06710059.1| conserved hypothetical protein [Streptomyces ... 50.4 3e-04 gb|EBL29221.1| hypothetical protein GOS_8595230 [marine metagenome] 50.4 3e-04 ref|ZP_08568754.1| Putative restriction endonuclease [Rheinheime... 50.4 3e-04 ref|ZP_07388898.1| HNH endonuclease [Paenibacillus curdlanolytic... 50.4 3e-04 ref|ZP_00739309.1| HNH endonuclease family protein [Bacillus thu... 50.4 3e-04 gb|EDJ09760.1| hypothetical protein GOS_1755420 [marine metagenome] 50.4 3e-04 ref|ZP_06424640.1| Hnh [Peptostreptococcus anaerobius 653-L] >gb... 50.4 3e-04 ref|YP_004547052.1| HNH endonuclease [Desulfotomaculum ruminis D... 50.4 3e-04 ref|NP_969665.1| hypothetical protein Bd2878 [Bdellovibrio bacte... 50.4 3e-04 ref|YP_003726840.1| HNH endonuclease [Methanohalobium evestigatu... 50.1 4e-04 ref|YP_001950539.1| HNH endonuclease [Geobacter lovleyi SZ] >gb|... 50.1 4e-04 gb|EBU48765.1| hypothetical protein GOS_7107064 [marine metagenome] 49.7 5e-04 ref|YP_004464373.1| HNH endonuclease [Mahella australiensis 50-1... 49.7 5e-04 ref|ZP_08167457.1| hypothetical protein HMPREF9402_0852 [Turicib... 49.7 6e-04 ref|YP_002601669.1| putative 5-methylcytosine-specific restricti... 49.7 6e-04 gb|ECB21691.1| hypothetical protein GOS_5236864 [marine metagenome] 49.3 6e-04 ref|YP_003239728.1| HNH endonuclease [Ammonifex degensii KC4] >g... 49.3 7e-04 ref|YP_001321783.1| HNH endonuclease [Alkaliphilus metalliredige... 49.3 7e-04 gb|EBM37869.1| hypothetical protein GOS_8419518 [marine metagenome] 49.3 7e-04 ref|YP_097917.1| hypothetical protein BF0634 [Bacteroides fragil... 49.3 7e-04 ref|ZP_01170179.1| hypothetical protein B14911_16960 [Bacillus s... 49.3 8e-04 ref|ZP_05984078.1| 5-methylcytosine-specific restriction enzyme ... 48.9 9e-04 gb|EBU48867.1| hypothetical protein GOS_7106928 [marine metagenome] 48.5 0.001 gb|EBA98496.1| hypothetical protein GOS_308273 [marine metagenome] 48.5 0.001 gb|ECD84752.1| hypothetical protein GOS_5295183 [marine metagenome] 48.5 0.001 ref|YP_341779.1| putative HNH endonuclease [Pseudoalteromonas ha... 48.5 0.001 ref|ZP_00517558.1| HNH endonuclease [Crocosphaera watsonii WH 85... 48.5 0.001 ref|ZP_07673316.1| product McrA [Erysipelotrichaceae bacterium 3... 48.5 0.001 ref|YP_090375.1| hypothetical protein BLi00747 [Bacillus licheni... 48.1 0.001 ref|ZP_07399124.1| HNH endonuclease domain protein [Peptoniphilu... 48.1 0.001 ref|YP_003726457.1| HNH endonuclease [Methanohalobium evestigatu... 48.1 0.001 ref|YP_003727124.1| HNH endonuclease [Methanohalobium evestigatu... 48.1 0.002 ref|ZP_00513911.1| RNA-directed DNA polymerase (Reverse transcri... 48.1 0.002 ref|ZP_08324079.1| HNH endonuclease domain protein [Parasutterel... 48.1 0.002 ref|ZP_07758536.1| HNH endonuclease domain protein [Enterococcus... 47.8 0.002 ref|ZP_08044848.1| HNH endonuclease domain protein [Haladaptatus... 47.8 0.002 ref|ZP_00518164.1| HNH endonuclease [Crocosphaera watsonii WH 85... 47.8 0.002 ref|ZP_08107522.1| HNH endonuclease [Clostridium symbiosum WAL-1... 47.8 0.002 ref|ZP_07289254.1| HNH endonuclease [Streptomyces sp. C] >gb|EFL... 47.8 0.002 ref|YP_003238831.1| HNH endonuclease [Ammonifex degensii KC4] >g... 47.8 0.002 ref|YP_003220843.1| endonuclease-like protein [Escherichia coli ... 47.8 0.002 gb|EGB62750.1| HNH endonuclease [Escherichia coli M863] 47.8 0.002 ref|ZP_07932753.1| HNH endonuclease [Anaerostipes sp. 3_2_56FAA]... 47.8 0.002 ref|ZP_07831699.1| HNH endonuclease domain protein [Clostridium ... 47.8 0.002 gb|EBK30658.1| hypothetical protein GOS_8754332 [marine metagenome] 47.8 0.002 ref|YP_003376869.1| hypothetical protein XALc_2397 [Xanthomonas ... 47.8 0.002 ref|ZP_08001265.1| hypothetical protein HMPREF1012_02303 [Bacill... 47.4 0.002 ref|ZP_05596803.1| predicted protein [Enterococcus faecalis T11]... 47.4 0.002 gb|EBL67753.1| hypothetical protein GOS_8532417 [marine metagenome] 47.4 0.002 ref|YP_004113653.1| HNH endonuclease [Desulfurispirillum indicum... 47.4 0.002 gb|ECD32245.1| hypothetical protein GOS_3904965 [marine metagenome] 47.4 0.003 ref|ZP_08148126.1| hypothetical protein HMPREF9417_0867 [Haemoph... 47.4 0.003 ref|NP_680905.1| maturase; reverse transcriptase [Thermosynechoc... 47.4 0.003 ref|ZP_06945735.1| HNH endonuclease domain protein [Finegoldia m... 47.0 0.003 gb|EGC81795.1| HNH endonuclease domain protein [Anaerococcus pre... 47.0 0.003 ref|YP_120439.1| putative endonuclease [Nocardia farcinica IFM 1... 47.0 0.003 ref|YP_004199626.1| HNH endonuclease [Geobacter sp. M18] >gb|ADW... 47.0 0.003 ref|ZP_01628404.1| hypothetical protein N9414_14925 [Nodularia s... 47.0 0.004 ref|ZP_00514209.1| RNA-directed DNA polymerase [Crocosphaera wat... 47.0 0.004 ref|YP_003238553.1| HNH endonuclease [Ammonifex degensii KC4] >g... 47.0 0.004 ref|YP_003534492.1| HNH endonuclease domain-containing protein [... 46.6 0.004 gb|AEG70099.1| conserved hypothetical protein [Ralstonia solanac... 46.6 0.004 gb|EGF39969.1| hypothetical protein VP10329_22848 [Vibrio paraha... 46.6 0.004 ref|ZP_00514520.1| HNH endonuclease [Crocosphaera watsonii WH 85... 46.6 0.004 ref|YP_735330.1| hypothetical protein Shewmr4_3203 [Shewanella s... 46.6 0.004 ref|ZP_06560205.1| HNH endonuclease domain protein [Megasphaera ... 46.6 0.004 ref|ZP_01622212.1| hypothetical protein L8106_02712 [Lyngbya sp.... 46.6 0.004 gb|AAU87367.1| MnlI restriction endonuclease [Moraxella nonlique... 46.6 0.004 gb|EBJ96700.1| hypothetical protein GOS_8810499 [marine metagenome] 46.6 0.004 ref|ZP_08334725.1| hypothetical protein HMPREF0987_01028 [Lachno... 46.6 0.004 ref|ZP_05615751.1| putative HNH endonuclease domain protein [Fae... 46.6 0.005 ref|ZP_07388892.1| HNH endonuclease [Paenibacillus curdlanolytic... 46.6 0.005 ref|YP_004464780.1| HNH endonuclease [Mahella australiensis 50-1... 46.6 0.005 gb|ECE17206.1| hypothetical protein GOS_4015603 [marine metagenome] 46.6 0.005 ref|ZP_08564108.1| recombinase [Lactobacillus ruminis SPM0211] >... 46.2 0.005 ref|ZP_08079957.1| recombinase [Lactobacillus ruminis ATCC 25644... 46.2 0.005 ref|YP_305634.1| hypothetical protein Mbar_A2123 [Methanosarcina... 46.2 0.005 ref|ZP_00514900.1| RNA-directed DNA polymerase (Reverse transcri... 46.2 0.005 ref|YP_871419.1| HNH endonuclease [Shewanella sp. ANA-3] >gb|ABK... 46.2 0.006 gb|ADW79676.1| putative HNH endonuclease [Salmonella enterica su... 46.2 0.006 ref|ZP_00515193.1| HNH endonuclease [Crocosphaera watsonii WH 85... 46.2 0.006 ref|NP_943492.1| HNH endonuclease [Klebsiella pneumoniae] >gb|AA... 46.2 0.006 ref|ZP_04172360.1| hypothetical protein bmyco0001_56780 [Bacillu... 46.2 0.006 ref|YP_002886492.1| HNH endonuclease [Exiguobacterium sp. AT1b] ... 46.2 0.006 ref|ZP_03065878.1| Hnh [Shigella dysenteriae 1012] >gb|EDX34285.... 46.2 0.006 ref|NP_681791.1| reverse transcriptase [Thermosynechococcus elon... 46.2 0.006 ref|YP_001687961.1| HNH endonuclease [Klebsiella pneumoniae NTUH... 46.2 0.006 ref|ZP_01069662.1| MnlI restriction endonuclease [Campylobacter ... 46.2 0.006 gb|EBY67131.1| hypothetical protein GOS_4901265 [marine metagenome] 46.2 0.006 ref|ZP_06964988.1| RNA-directed DNA polymerase (Reverse transcri... 46.2 0.006 ref|ZP_06966392.1| RNA-directed DNA polymerase (Reverse transcri... 46.2 0.007 ref|ZP_06964959.1| RNA-directed DNA polymerase (Reverse transcri... 46.2 0.007 ref|NP_681409.1| reverse transcriptase [Thermosynechococcus elon... 46.2 0.007 ref|ZP_06968421.1| RNA-directed DNA polymerase (Reverse transcri... 45.8 0.007 ref|ZP_06966276.1| RNA-directed DNA polymerase (Reverse transcri... 45.8 0.007 gb|ECN95299.1| hypothetical protein GOS_3902663 [marine metagenome] 45.8 0.007 ref|ZP_06965526.1| RNA-directed DNA polymerase (Reverse transcri... 45.8 0.007 ref|ZP_08431987.1| restriction endonuclease [Lyngbya majuscula 3... 45.8 0.007 ref|YP_003602536.1| HNH endonuclease [Enterobacter cloacae subsp... 45.8 0.007 ref|ZP_04558947.1| HNH endonuclease [Citrobacter sp. 30_2] >gb|E... 45.8 0.007 ref|NP_618379.1| HNH endonuclease [Methanosarcina acetivorans C2... 45.8 0.007 ref|ZP_08603840.1| hypothetical protein HMPREF0993_03217 [Lachno... 45.8 0.007 ref|ZP_04625948.1| HNH nuclease [Yersinia kristensenii ATCC 3363... 45.8 0.007 gb|ECQ08039.1| hypothetical protein GOS_3561047 [marine metagenome] 45.8 0.007 gb|EBK97491.1| hypothetical protein GOS_8644481 [marine metagenome] 45.8 0.008 ref|NP_680822.1| reverse transcriptase [Thermosynechococcus elon... 45.8 0.008 ref|NP_681951.1| reverse transcriptase [Thermosynechococcus elon... 45.8 0.008 ref|ZP_00517210.1| RNA-directed DNA polymerase (Reverse transcri... 45.8 0.008 ref|YP_003672198.1| HNH endonuclease [Geobacillus sp. C56-T3] >g... 45.8 0.008 ref|NP_681099.1| reverse transcriptase [Thermosynechococcus elon... 45.8 0.008 ref|ZP_00513655.1| HNH endonuclease [Crocosphaera watsonii WH 85... 45.8 0.008 ref|YP_001133838.1| HNH endonuclease [Mycobacterium gilvum PYR-G... 45.8 0.008 ref|YP_003887722.1| RNA-directed DNA polymerase [Cyanothece sp. ... 45.8 0.008 ref|ZP_00518382.1| HNH endonuclease [Crocosphaera watsonii WH 85... 45.8 0.008 ref|ZP_04556006.1| predicted protein [Bacteroides sp. D4] >gb|EE... 45.8 0.008 ref|ZP_07323074.1| HNH endonuclease domain protein [Prevotella d... 45.4 0.009 gb|EDJ12277.1| hypothetical protein GOS_1750925 [marine metagenome] 45.4 0.009 gb|ECS44854.1| hypothetical protein GOS_4663789 [marine metagenome] 45.4 0.009 ref|ZP_01903770.1| HNH nuclease [Roseobacter sp. AzwK-3b] >gb|ED... 45.4 0.009 ref|ZP_04658302.1| conserved hypothetical protein [Selenomonas f... 45.4 0.009 ref|YP_180821.1| HNH endonuclease domain-containing protein [Deh... 45.4 0.009 ref|ZP_00515251.1| HNH endonuclease [Crocosphaera watsonii WH 85... 45.4 0.009 ref|ZP_06080041.1| HNH endonuclease [Vibrio sp. RC586] >ref|ZP_0... 45.4 0.010 ref|ZP_07298326.1| HNH endonuclease [Streptomyces hygroscopicus ... 45.4 0.010 gb|EBO04682.1| hypothetical protein GOS_8146055 [marine metagenome] 45.4 0.010 gb|AAL25965.1| group II intron-associated open reading frame [Az... 45.4 0.011 gb|ECD99344.1| hypothetical protein GOS_4710496 [marine metagenome] 45.4 0.011 ref|YP_002798550.1| RNA-directed DNA polymerase [Azotobacter vin... 45.4 0.011 ref|ZP_00517704.1| HNH endonuclease [Crocosphaera watsonii WH 85... 45.1 0.011 ref|YP_846912.1| HNH endonuclease [Syntrophobacter fumaroxidans ... 45.1 0.011 gb|EBG19539.1| hypothetical protein GOS_9474002 [marine metagenome] 45.1 0.011 ref|YP_003049279.1| HNH endonuclease [Methylotenera mobilis JLW8... 45.1 0.012 ref|YP_003387900.1| HNH endonuclease [Spirosoma linguale DSM 74]... 45.1 0.012 ref|YP_003212816.1| hypothetical protein Ctu_3p00720 [Cronobacte... 45.1 0.012 ref|YP_004522610.1| HNH endonuclease [Mycobacterium sp. JDM601] ... 45.1 0.012 ref|ZP_07111177.1| RNA-directed DNA polymerase [Oscillatoria sp.... 45.1 0.012 ref|ZP_00514944.1| RNA-directed DNA polymerase (Reverse transcri... 45.1 0.012 gb|ECJ49505.1| hypothetical protein GOS_4102383 [marine metagenome] 45.1 0.013 gb|EBO93923.1| hypothetical protein GOS_7994644 [marine metagenome] 45.1 0.013 gb|EBB89770.1| hypothetical protein GOS_157721 [marine metagenome] 45.1 0.013 gb|EBS57030.1| hypothetical protein GOS_7416319 [marine metagenome] 45.1 0.013 ref|YP_190191.1| HNH endonuclease [Escherichia coli] >gb|AAT3758... 45.1 0.013 ref|YP_001263031.1| HNH endonuclease [Sphingomonas wittichii RW1... 45.1 0.013 ref|YP_003406404.1| HNH endonuclease [Haloterrigena turkmenica D... 45.1 0.013 ref|ZP_04151047.1| Paclitaxel/taxanoid biosynthesis susceptibili... 45.1 0.014 ref|YP_002507119.1| HNH endonuclease [Clostridium cellulolyticum... 45.1 0.014 ref|YP_736616.1| RNA-directed DNA polymerase [Shewanella sp. MR-... 45.1 0.014 ref|ZP_04611051.1| hypothetical protein yrohd0001_28640 [Yersini... 44.7 0.015 ref|YP_001662871.1| HNH endonuclease [Thermoanaerobacter sp. X51... 44.7 0.015 gb|EBS50833.1| hypothetical protein GOS_7426096 [marine metagenome] 44.7 0.015 ref|YP_003740994.1| endonuclease [Erwinia billingiae Eb661] >emb... 44.7 0.015 ref|YP_003398766.1| HNH endonuclease [Acidaminococcus fermentans... 44.7 0.016 ref|ZP_00515756.1| RNA-directed DNA polymerase [Crocosphaera wat... 44.7 0.016 ref|ZP_00515528.1| RNA-directed DNA polymerase [Crocosphaera wat... 44.7 0.016 ref|YP_001659893.1| RNA-directed DNA polymerase [Microcystis aer... 44.7 0.017 ref|ZP_06966112.1| HNH endonuclease [Ktedonobacter racemifer DSM... 44.7 0.018 ref|YP_003343236.1| hypothetical protein Sros_7830 [Streptospora... 44.7 0.018 ref|ZP_04098620.1| HNH endonuclease [Bacillus thuringiensis sero... 44.7 0.018 ref|YP_002449968.1| DNA helicase, putative [Bacillus cereus AH82... 44.7 0.018 ref|ZP_06178472.1| hypothetical protein VME_48560 [Vibrio harvey... 44.7 0.019 gb|EBA72621.1| hypothetical protein GOS_352954 [marine metagenome] 44.7 0.019 ref|ZP_05721581.1| conserved hypothetical protein [Vibrio mimicu... 44.7 0.019 gb|EBN63893.1| hypothetical protein GOS_8213048 [marine metagenome] 44.3 0.019 ref|ZP_08558482.1| hypothetical protein HLRTI_01252 [Halorhabdus... 44.3 0.020 ref|ZP_07959296.1| HNH endonuclease domain-containing protein [L... 44.3 0.020 ref|YP_692355.1| reverse transcriptase/maturase-like protein [Al... 44.3 0.020 ref|ZP_00516851.1| RNA-directed DNA polymerase (Reverse transcri... 44.3 0.020 ref|ZP_03104429.1| gp45 [Bacillus cereus W] >gb|EDX54271.1| gp45... 44.3 0.021 ref|YP_001038057.1| HNH endonuclease [Clostridium thermocellum A... 44.3 0.021 ref|ZP_00516498.1| RNA-directed DNA polymerase (Reverse transcri... 44.3 0.021 gb|EBG33586.1| hypothetical protein GOS_9450142 [marine metagenome] 44.3 0.021 ref|ZP_04632181.1| HNH nuclease [Yersinia frederiksenii ATCC 336... 44.3 0.021 ref|ZP_00517863.1| RNA-directed DNA polymerase (Reverse transcri... 44.3 0.022 ref|ZP_08432327.1| RNA-directed DNA polymerase [Lyngbya majuscul... 44.3 0.024 ref|ZP_03841307.1| hypothetical protein HMPREF0693_2198 [Proteus... 44.3 0.024 ref|ZP_00514784.1| HNH endonuclease [Crocosphaera watsonii WH 85... 44.3 0.024 gb|ECA33447.1| hypothetical protein GOS_5260325 [marine metagenome] 44.3 0.024 ref|ZP_06968411.1| HNH endonuclease [Ktedonobacter racemifer DSM... 43.9 0.025 ref|YP_002462285.1| HNH endonuclease [Chloroflexus aggregans DSM... 43.9 0.025 ref|YP_117808.1| hypothetical protein nfa15980 [Nocardia farcini... 43.9 0.025 gb|EGL98736.1| paclitaxel/taxanoid biosynthesis susceptibility p... 43.9 0.026 ref|YP_001100121.1| putative restriction endonuclease [Herminiim... 43.9 0.026 ref|YP_001285917.1| hypothetical protein [Lactobacillus phage LL... 43.9 0.026 gb|ECT47599.1| hypothetical protein GOS_5822885 [marine metagenome] 43.9 0.026 gb|EBJ67529.1| hypothetical protein GOS_8858845 [marine metagenome] 43.9 0.027 ref|ZP_04161902.1| Hnh endonuclease [Bacillus mycoides Rock1-4] ... 43.9 0.027 gb|EGL98264.1| paclitaxel/taxanoid biosynthesis susceptibility p... 43.9 0.027 ref|YP_001520477.1| RNA-directed DNA polymerase [Acaryochloris m... 43.9 0.028 ref|ZP_00517871.1| HNH endonuclease [Crocosphaera watsonii WH 85... 43.9 0.028 ref|ZP_00516633.1| RNA-directed DNA polymerase (Reverse transcri... 43.9 0.028 ref|ZP_08305237.1| HNH endonuclease domain protein [Klebsiella s... 43.9 0.029 ref|ZP_01675841.1| HNH endonuclease domain protein [Vibrio chole... 43.9 0.029 ref|YP_002917583.1| hypothetical protein KP1_0666 [Klebsiella pn... 43.9 0.030 ref|YP_002472815.1| hypothetical protein CKR_2350 [Clostridium k... 43.9 0.030 ref|NP_301904.1| hypothetical protein ML1254 [Mycobacterium lepr... 43.9 0.030 ref|ZP_06973729.1| HNH endonuclease [Ktedonobacter racemifer DSM... 43.9 0.030 ref|YP_001396035.1| hypothetical protein CKL_2652 [Clostridium k... 43.9 0.030 ref|YP_002017592.1| HNH nuclease [Pelodictyon phaeoclathratiform... 43.9 0.031 ref|YP_001338337.1| hypothetical protein KPN_04720 [Klebsiella p... 43.9 0.031 ref|YP_004516156.1| HNH endonuclease [Desulfotomaculum kuznetsov... 43.9 0.032 ref|YP_002545821.1| hypothetical protein Arad_4103 [Agrobacteriu... 43.9 0.032 ref|ZP_08431996.1| group II catalytic intron [Lyngbya majuscula ... 43.9 0.032 ref|ZP_01222701.1| hypothetical protein P3TCK_08708 [Photobacter... 43.9 0.032 ref|YP_961686.1| HNH nuclease [Shewanella sp. W3-18-1] >gb|ABM23... 43.5 0.033 ref|YP_358357.1| HNH endonuclease family protein [Pelobacter car... 43.5 0.033 gb|EFZ52303.1| HNH endonuclease family protein [Shigella sonnei ... 43.5 0.034 ref|ZP_06974220.1| HNH endonuclease [Ktedonobacter racemifer DSM... 43.5 0.034 gb|EBO44951.1| hypothetical protein GOS_8078522 [marine metagenome] 43.5 0.034 ref|ZP_03130774.1| HNH endonuclease [Chthoniobacter flavus Ellin... 43.5 0.035 ref|ZP_06973478.1| HNH endonuclease [Ktedonobacter racemifer DSM... 43.5 0.035 ref|YP_001702306.1| HNH endonuclease precursor [Mycobacterium ab... 43.5 0.035 ref|ZP_01903583.1| HNH nuclease [Roseobacter sp. AzwK-3b] >gb|ED... 43.5 0.035 ref|ZP_06018175.1| conserved hypothetical protein [Klebsiella pn... 43.5 0.036 ref|YP_001813876.1| HNH endonuclease [Exiguobacterium sibiricum ... 43.5 0.037 ref|YP_004451260.1| RNA-directed DNA polymerase [Haliscomenobact... 43.5 0.037 ref|ZP_00516558.1| HNH endonuclease [Crocosphaera watsonii WH 85... 43.5 0.037 ref|YP_001741912.1| Putative ATP dependant helicase yprA [Candid... 43.5 0.038 ref|ZP_02418181.1| hypothetical protein ANACAC_00749 [Anaerostip... 43.5 0.038 ref|YP_181809.1| HNH endonuclease domain-containing protein [Deh... 43.5 0.038 gb|EDH61950.1| hypothetical protein GOS_572715 [marine metagenome] 43.5 0.039 ref|YP_001629663.1| reverse transcriptase [Bordetella petrii DSM... 43.5 0.040 gb|ECV22780.1| hypothetical protein GOS_2939756 [marine metagenome] 43.5 0.040 ref|ZP_07415077.2| hypothetical protein TMAG_03028 [Mycobacteriu... 43.5 0.041 gb|ECW12781.1| hypothetical protein GOS_2775814 [marine metagenome] 43.5 0.041 ref|YP_001859320.1| hypothetical protein Bphy_3106 [Burkholderia... 43.5 0.042 ref|NP_489471.1| hypothetical protein alr8560 [Nostoc sp. PCC 71... 43.5 0.042 ref|NP_856143.1| hypothetical protein Mb2496c [Mycobacterium bov... 43.1 0.043 ref|NP_216985.1| hypothetical protein Rv2469c [Mycobacterium tub... 43.1 0.043 ref|YP_004064966.1| hypothetical protein PSM_B0017 [Pseudoaltero... 43.1 0.044 ref|YP_003827677.1| HNH endonuclease [Acetohalobium arabaticum D... 43.1 0.048 ref|YP_002955051.1| hypothetical protein DMR_36740 [Desulfovibri... 43.1 0.048 ref|ZP_02419892.1| hypothetical protein ANACAC_02486 [Anaerostip... 43.1 0.048 ref|YP_001869520.1| HNH endonuclease [Nostoc punctiforme PCC 731... 43.1 0.049 ref|ZP_01114653.1| hypothetical protein MED297_02697 [Reinekea s... 43.1 0.050 ref|YP_002507438.1| HNH endonuclease [Clostridium cellulolyticum... 43.1 0.052 ref|YP_503131.1| HNH endonuclease [Methanospirillum hungatei JF-... 43.1 0.052 ref|YP_002923607.1| group II intron encoded reverse transcriptas... 43.1 0.053 gb|ECD28212.1| hypothetical protein GOS_4057401 [marine metagenome] 43.1 0.053 gb|ADI08889.1| HNH endonuclease [Streptomyces bingchenggensis BC... 43.1 0.053 ref|YP_001404880.1| HNH endonuclease [Candidatus Methanoregula b... 43.1 0.053 ref|YP_002923208.1| group II intron encoded reverse transcriptas... 43.1 0.054 ref|YP_002924053.1| group II intron encoded reverse transcriptas... 43.1 0.055 ref|YP_002923472.1| group II intron encoded reverse transcriptas... 42.7 0.056 ref|YP_002923842.1| group II intron encoded reverse transcriptas... 42.7 0.057 ref|ZP_04445608.1| hypothetical protein COLINT_02319 [Collinsell... 42.7 0.057 gb|ECC23622.1| hypothetical protein GOS_4677668 [marine metagenome] 42.7 0.058 ref|ZP_07946421.1| HNH endonuclease [Eggerthella sp. 1_3_56FAA] ... 42.7 0.058 ref|ZP_01863197.1| hypothetical protein ED21_17542 [Erythrobacte... 42.7 0.058 gb|ECW21993.1| hypothetical protein GOS_2759552 [marine metagenome] 42.7 0.059 ref|ZP_06975574.1| HNH endonuclease [Ktedonobacter racemifer DSM... 42.7 0.060 ref|ZP_05760967.1| HNH endonuclease [Bacteroides sp. D2] 42.7 0.060 ref|YP_002240706.1| HNH endonuclease domain protein [Klebsiella ... 42.7 0.060 ref|NP_826380.1| hypothetical protein SAV_5203 [Streptomyces ave... 42.7 0.061 ref|ZP_08164082.1| HNH endonuclease domain protein [Eggerthella ... 42.7 0.061 gb|ECH14654.1| hypothetical protein GOS_6439444 [marine metagenome] 42.7 0.063 gb|EBQ78482.1| hypothetical protein GOS_7698254 [marine metagenome] 42.7 0.065 ref|YP_001544108.1| HNH endonuclease [Herpetosiphon aurantiacus ... 42.7 0.067 ref|YP_002574267.1| HNH endonuclease [Caldicellulosiruptor besci... 42.7 0.067 ref|YP_004034938.1| paclitaxel/taxanoid biosynthesis susceptibil... 42.7 0.068 ref|YP_002316571.1| Restriction endonuclease, McrA/HNH family, p... 42.7 0.069 ref|ZP_08150701.1| hypothetical protein HMPREF0490_01439 [Lachno... 42.7 0.071 ref|ZP_03168547.1| hypothetical protein RUMLAC_02230 [Ruminococc... 42.7 0.071 gb|ECW51057.1| hypothetical protein GOS_2708277 [marine metagenome] 42.4 0.073 ref|ZP_08507246.1| HNH endonuclease domain protein [Paenibacillu... 42.4 0.073 gb|EGE55763.1| HNH endonuclease [Rhizobium etli CNPAF512] 42.4 0.073 ref|ZP_06852050.1| HNH endonuclease [Mycobacterium parascrofulac... 42.4 0.074 ref|YP_004092082.1| HNH endonuclease [Ethanoligenens harbinense ... 42.4 0.074 ref|YP_002924030.1| group II intron encoded reverse transcriptas... 42.4 0.075 ref|YP_002017302.1| HNH nuclease [Pelodictyon phaeoclathratiform... 42.4 0.075 ref|ZP_04084218.1| hypothetical protein bthur0011_18910 [Bacillu... 42.4 0.076 ref|YP_003832012.1| HNH endonuclease domain-containing protein [... 42.4 0.078 ref|ZP_08123508.1| HNH endonuclease [Pseudonocardia sp. P1] 42.4 0.079 ref|ZP_07091867.1| HNH endonuclease domain protein [Lactobacillu... 42.4 0.079 ref|ZP_04749602.1| hypothetical protein MkanA1_16649 [Mycobacter... 42.4 0.079 gb|ECE78321.1| hypothetical protein GOS_5306722 [marine metagenome] 42.4 0.082 ref|ZP_07919062.1| HNH endonuclease [Bacteroides sp. D2] >gb|EFS... 42.4 0.083 ref|ZP_00516550.1| HNH endonuclease [Crocosphaera watsonii WH 85... 42.4 0.083 ref|ZP_00515999.1| HNH endonuclease [Crocosphaera watsonii WH 85... 42.4 0.084 ref|ZP_00517484.1| HNH endonuclease [Crocosphaera watsonii WH 85... 42.4 0.084 ref|YP_530866.1| HNH endonuclease [Rhodopseudomonas palustris Bi... 42.4 0.086 ref|YP_003300100.1| HNH endonuclease [Thermomonospora curvata DS... 42.4 0.087 ref|ZP_08532266.1| HNH endonuclease [Caldalkalibacillus thermaru... 42.4 0.089 ref|ZP_06645285.1| HNH endonuclease domain protein [Erysipelotri... 42.4 0.089 gb|ECZ31859.1| hypothetical protein GOS_2204502 [marine metagenome] 42.4 0.093 ref|ZP_02430016.1| hypothetical protein CLOSCI_00220 [Clostridiu... 42.4 0.093 gb|ECI80139.1| hypothetical protein GOS_3362985 [marine metagenome] 42.0 0.096 gb|EBL67005.1| hypothetical protein GOS_8533628 [marine metagenome] 42.0 0.096 ref|ZP_08099255.1| hypothetical protein VIBR0546_17828 [Vibrio b... 42.0 0.096 ref|YP_076086.1| hypothetical protein STH2257 [Symbiobacterium t... 42.0 0.096 gb|EBX22824.1| hypothetical protein GOS_6620896 [marine metagenome] 42.0 0.099 ref|ZP_06249312.1| HNH endonuclease [Clostridium thermocellum JW... 42.0 0.100 >ref|NP_415677.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Escherichia coli str. K-12 substr. MG1655] ref|AP_001784.1| 5-methylcytosine-specific restriction endonuclease B [Escherichia coli str. K-12 substr. W3110] ref|ZP_05432459.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Shigella sp. D9] 45 more sequence titles

ref|ZP_06661904.1| 5-methylcytosine-specific restriction enzyme A [Escherichia coli B088] ref|ZP_08392075.1| methyl cytosine restriction enzyme [Shigella sp. D9] sp|P24200.2|MCRA_ECOLI RecName: Full=5-methylcytosine-specific restriction enzyme A; AltName: Full=EcoKMcrA emb|CAA79520.1| methyl cytosine restriction enzyme [Escherichia coli] gb|AAA68481.1| mcrA [Escherichia coli] dbj|BAA35995.1| 5-methylcytosine-specific restriction endonuclease B [Escherichia coli str. K12 substr. W3110] gb|AAC74243.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Escherichia coli str. K-12 substr. MG1655] gb|ACX40125.1| HNH endonuclease [Escherichia coli DH1] gb|EFE63717.1| 5-methylcytosine-specific restriction enzyme A [Escherichia coli B088] dbj|BAJ42951.1| 5-methylcytosine-specific restriction enzyme A [Escherichia coli DH1] gb|EFY13532.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 315996572] gb|EFY16736.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 495297-1] gb|EFY19275.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 495297-3] gb|EFY24744.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 495297-4] gb|EFY29691.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 515920-1] gb|EFY33509.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 515920-2] gb|EFY41687.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. NC_MB110209-0054] gb|EFY46512.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. OH_2009072675] gb|EFY51975.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. CASC_09SCPH15965] gb|EFY56236.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 19N] gb|EFY61623.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 81038-01] gb|EFY63748.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. MD_MDA09249507] gb|EFY69721.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 414877] gb|EFY73609.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 366867] gb|EFY75829.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 413180] gb|EFY83235.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 446600] gb|EFZ72693.1| HNH endonuclease family protein [Escherichia coli RN587/1] gb|EFZ77610.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 609458-1] gb|EFZ84551.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 556150-1] gb|EFZ88669.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 609460] gb|EFZ93749.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 507440-20] gb|EFZ98911.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 556152] gb|EGA02502.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. MB101509-0077] gb|EGA09229.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. MB110209-0055] gb|EGA13713.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. MB111609-0052] gb|EGA16909.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 2009083312] gb|EGA24193.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 2009085258] gb|EGA26885.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. 315731156] gb|EGA31735.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. IA_2009159199] gb|EGA38137.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008282] gb|EGA39835.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008283] gb|EGA43056.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008284] gb|EGA50501.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008285] gb|EGA55534.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. IA_2010008287] gb|EGJ05360.1| methyl cytosine restriction enzyme [Shigella sp. D9]

Length=277 Score = 574 bits (1479), Expect = 7e-162, Method: Compositional matrix adjust. Identities = 277/277 (100%), Positives = 277/277 (100%), Gaps = 0/277 (0%) Query 1 MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60 MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV Sbjct 1 MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60 Query 61 VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120 VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR Sbjct 61 VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120 Query 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV Sbjct 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180 Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT Sbjct 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK Sbjct 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 >gb|EGA03413.1| e14 prophage; 5-methylcytosine-specific restriction endonuclease B [Salmonella enterica subsp. enterica serovar Montevideo str. MB102109-0047] Length=270 Score = 543 bits (1399), Expect = 1e-152, Method: Compositional matrix adjust. Identities = 261/262 (99%), Positives = 261/262 (99%), Gaps = 0/262 (0%) Query 1 MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60 MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV Sbjct 1 MHVFDNNGIELKAECSIGEEDGVYGLILESWGPGDRNKDYNIALDYIIERLVDSGVSQVV 60 Query 61 VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120 VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR Sbjct 61 VYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNR 120 Query 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV Sbjct 121 TKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPV 180 Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT Sbjct 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 Query 241 TDNCVALCPNCHRELHYSKNAK 262 TDNCVALCPNCHRELHYSKN K Sbjct 241 TDNCVALCPNCHRELHYSKNDK 262 >ref|YP_001564178.1| HNH endonuclease [Delftia acidovorans SPH-1] gb|ABX35793.1| HNH endonuclease [Delftia acidovorans SPH-1] Length=330 Score = 131 bits (330), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 57/111 (51%), Positives = 75/111 (67%), Gaps = 0/111 (0%) Query 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224 L K ++P G+ P + R + RDP VKAW+L+++ G+CE C NAPF DG P+ Sbjct 217 LENKKQAKPAGNSNPGTIIRQVAQFERDPAVKAWVLKKAAGVCECCSSNAPFESTDGQPF 276 Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 LEVHH+ L+ GG+DT N VALCPNCHR LHY AKELIE +++ +NRL Sbjct 277 LEVHHIRKLAEGGSDTVSNTVALCPNCHRALHYGMRAKELIESIFIKVNRL 327 >ref|YP_002874288.1| putative 5-methylcytosine-specific restriction enzyme [Pseudomonas fluorescens SBW25] emb|CAY51603.1| putative 5-methylcytosine-specific restriction enzyme [Pseudomonas fluorescens SBW25] Length=237 Score = 128 bits (322), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 61/133 (45%), Positives = 84/133 (63%), Gaps = 2/133 (1%) Query 146 SELSQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204 S+ + T DE L R SKL ++ +Q P+G +P +V + +VRDP V+AW+L+++K Sbjct 105 SDDAAQTADEQTLIRRASKLQQQPFTQLPDGIAQPQKVSTVSTAFVRDPKVRAWVLKEAK 164 Query 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264 GICE CG NAPF + DG P+LEVHHV L+ G+D N VALCPNCH+ H S + Sbjct 165 GICEGCGSNAPFEV-DGLPFLEVHHVKHLAQKGSDRISNAVALCPNCHQRCHRSSDRDAF 223 Query 265 IEMLYVNINRLQK 277 E LY + RL + Sbjct 224 TEGLYAKVGRLAR 236 >ref|ZP_07777116.1| HNH endonuclease [Pseudomonas fluorescens WH6] gb|EFQ61594.1| HNH endonuclease [Pseudomonas fluorescens WH6] Length=237 Score = 126 bits (317), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 62/131 (47%), Positives = 83/131 (63%), Gaps = 2/131 (1%) Query 146 SELSQPTDDESLLNMRVSKLIKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204 SE + T DE L R SKL ++ + P+G +P +V + +VRDP V+AW+L+++K Sbjct 105 SEDAAQTADEQTLIRRASKLQQQPFPKLPDGIAQPQKVSTVSTSFVRDPKVRAWVLKEAK 164 Query 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264 GICE CG NAPF + DG P+LEVHHV L+ G+D N VALCPNCH+ H S + + Sbjct 165 GICEGCGSNAPFEV-DGLPFLEVHHVKHLAQKGSDRITNAVALCPNCHQRCHQSSDREAF 223 Query 265 IEMLYVNINRL 275 E LY I RL Sbjct 224 TEGLYAKIGRL 234 >gb|ECO37670.1| hypothetical protein GOS_5707677 [marine metagenome] Length=231 Score = 125 bits (315), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 55/103 (53%), Positives = 71/103 (68%), Gaps = 0/103 (0%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 P GS+KP + YVRDP V AWIL + G+CE C K APFY DG +LEVHH+ Sbjct 126 PTGSKKPKRTQTSSTKYVRDPEVVAWILNFANGMCECCKKPAPFYKEDGASFLEVHHLKQ 185 Query 233 LSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 L+ GG+DTT+N +A+CPNCHRELH+ KN +L +Y ++NRL Sbjct 186 LADGGSDTTNNAIAICPNCHRELHFGKNKSDLKMKVYKSVNRL 228 >ref|YP_065769.1| 5-methylcytosine-specific restriction enzyme A [Desulfotalea psychrophila LSv54] emb|CAG36762.1| probable 5-methylcytosine-specific restriction enzyme A [Desulfotalea psychrophila LSv54] Length=237 Score = 124 bits (310), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 81/220 (36%), Positives = 108/220 (49%), Gaps = 15/220 (6%) Query 64 ASSSVRKHMHSLDERK---IHPGEYFTL---IGNSPRDIRLKMCGYQAYFSRTGRKEIPS 117 AS MHSL+ R + Y TL G + + +M +S GR+ + Sbjct 22 ASVDAYVEMHSLEARGKPFVKKAYYETLANTFGRTVKSYEYRMQNISYVYSLQGRQWVSG 81 Query 118 GNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLS-QPEGS 176 + + +NV + D I + E L + N V KL K+ S P+G+ Sbjct 82 LKPARNVGVNVIQMLEDL----IAKSEGQHLVAI----AYFNAAVEKLRKRPPSLPPKGN 133 Query 177 RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG 236 +KP +VRDP V AW+L ++ G CE C +APF DG+P+LEVHHV L+ Sbjct 134 KKPASFLSSGTRFVRDPEVVAWVLAEAAGHCECCESSAPFLREDGSPFLEVHHVQHLADH 193 Query 237 GADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276 G DT +N VALCPNCH ELHY KEL E L I RLQ Sbjct 194 GEDTINNAVALCPNCHSELHYGMGKKELAEELRAKITRLQ 233 >ref|YP_412292.1| HNH nuclease [Nitrosospira multiformis ATCC 25196] gb|ABB74900.1| HNH nuclease [Nitrosospira multiformis ATCC 25196] Length=226 Score = 122 bits (305), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 57/115 (49%), Positives = 77/115 (66%), Gaps = 8/115 (6%) Query 167 KKTLSQPEGSRKP----VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN 222 +K L +P G+ +P + V +L+ RDP VKAW+LQQ+ G CE+C K APF DG+ Sbjct 115 QKDLPKPSGNPRPKRRRISVAQLE----RDPNVKAWVLQQAAGTCESCEKPAPFQGADGS 170 Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 PYLE+H+V L+ GGAD N VALCPNCHRE+HY NA+ + LY + RL++ Sbjct 171 PYLELHYVQGLADGGADAVSNAVALCPNCHREIHYGANAQAVEAWLYDTVQRLER 225 >ref|YP_856158.1| 5-methylcytosine-specific restriction protein A [Aeromonas hydrophila subsp. hydrophila ATCC 7966] gb|ABK39150.1| probable 5-methylcytosine-specific restriction enzyme A [Aeromonas hydrophila subsp. hydrophila ATCC 7966] Length=246 Score = 120 bits (302), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 64/140 (45%), Positives = 83/140 (59%), Gaps = 2/140 (1%) Query 138 ASIIRGELSEL-SQPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195 A II L EL QP ++ +VS+ IK TL P G ++P + Y RDP V Sbjct 104 APIIERLLCELDGQPYTGKAAFEHQVSRYKIKPTLPMPIGIQEPQQRYGANTSYGRDPKV 163 Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255 KAW+L + G CE+C + APF+ G+ +LEVHH+ L+ GG+DT N VALCPNCHREL Sbjct 164 KAWVLMTAVGRCESCAQPAPFHATTGDAFLEVHHLRTLAEGGSDTISNTVALCPNCHREL 223 Query 256 HYSKNAKELIEMLYVNINRL 275 HY N + E LY + RL Sbjct 224 HYGVNQAQKREALYQALPRL 243 >gb|EDA49155.1| hypothetical protein GOS_1991726 [marine metagenome] Length=260 Score = 120 bits (300), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 63/140 (45%), Positives = 82/140 (58%), Gaps = 2/140 (1%) Query 138 ASIIRGELSEL-SQPTDDESLLNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195 A II L EL QP ++ +VS+ IK L P G ++P + Y RDP V Sbjct 118 APIIERLLCELDGQPYTGKAAFEHQVSRYKIKPVLPTPIGIQEPQQRYATNTSYGRDPKV 177 Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255 KAW+L + G CE+C + APF+ G+ +LEVHH+ L+ GG+DT N VALCPNCHREL Sbjct 178 KAWVLMTAAGHCESCAQPAPFHATTGDAFLEVHHLRTLAEGGSDTISNTVALCPNCHREL 237 Query 256 HYSKNAKELIEMLYVNINRL 275 HY N + E LY + RL Sbjct 238 HYGVNQAQKREALYQALPRL 257 >ref|YP_001584201.1| HNH endonuclease [Burkholderia multivorans ATCC 17616] ref|YP_001948671.1| 5-methylcytosine-specific restriction enzyme A [Burkholderia multivorans ATCC 17616] gb|ABX17909.1| HNH endonuclease [Burkholderia multivorans ATCC 17616] dbj|BAG46135.1| 5-methylcytosine-specific restriction enzyme A [Burkholderia multivorans ATCC 17616] Length=242 Score = 119 bits (299), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 58/115 (50%), Positives = 74/115 (64%), Gaps = 2/115 (1%) Query 164 KLIKKTLSQPEGSRKPVEVERLQKVYVR-DPMVKAWILQQSKGICENCGKNAPFYLNDGN 222 +L + ++ P G+ +P EV VR DP VKAW+L Q++G CE CG APF DG Sbjct 128 RLKRVPVAPPTGNARP-EVGYATVAQVRRDPAVKAWVLAQARGTCECCGNPAPFADADGL 186 Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 PYLEVHHV L+ G D N VA+CPNCHRELHY + A+EL+E LY + RL + Sbjct 187 PYLEVHHVRRLAERGPDVISNAVAICPNCHRELHYGEKARELVERLYTRVPRLVR 241 >ref|ZP_03583033.1| HNH nuclease [Burkholderia multivorans CGD1] gb|EEE03206.1| HNH nuclease [Burkholderia multivorans CGD1] Length=205 Score = 119 bits (298), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 58/115 (50%), Positives = 74/115 (64%), Gaps = 2/115 (1%) Query 164 KLIKKTLSQPEGSRKPVEVERLQKVYVR-DPMVKAWILQQSKGICENCGKNAPFYLNDGN 222 +L + ++ P G+ +P EV VR DP VKAW+L Q++G CE CG APF DG Sbjct 91 RLKRVPVAPPTGNARP-EVGYATVAQVRRDPAVKAWVLAQARGTCECCGNPAPFADADGL 149 Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 PYLEVHHV L+ G D N VA+CPNCHRELHY + A+EL+E LY + RL + Sbjct 150 PYLEVHHVRRLAERGPDVISNAVAICPNCHRELHYGEKARELVERLYTRVPRLVR 204 >gb|EBZ73193.1| hypothetical protein GOS_4171158 [marine metagenome] Length=216 Score = 119 bits (297), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 57/120 (47%), Positives = 76/120 (63%), Gaps = 0/120 (0%) Query 156 SLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAP 215 S ++V L++ L++P G++ P ++ RD V AWI++ SKG+CE C K AP Sbjct 94 SRFELQVGDLLQGPLTKPNGTKIPKRKKQSSNAIERDAAVCAWIIENSKGLCECCKKPAP 153 Query 216 FYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 F N+G P LEVHHV LS GG+DT N VA+CPNCHRELH +++ L LY INRL Sbjct 154 FTKNNGLPGLEVHHVRQLSKGGSDTPQNAVAVCPNCHRELHLGVDSRNLTRRLYRTINRL 213 >gb|ECE40492.1| hypothetical protein GOS_3100346 [marine metagenome] Length=127 Score = 118 bits (296), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 53/114 (46%), Positives = 74/114 (64%), Gaps = 0/114 (0%) Query 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221 +S K LS+P G ++P + + RDP VKAW+L+++ G CE CG +APF +G Sbjct 11 ISYKTKVNLSKPSGIKEPEKTYSQVTNFNRDPKVKAWVLKEASGKCECCGSDAPFTTAEG 70 Query 222 NPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 P+LEVHH+ L+ GG+DT N VALCPNCHRE+HY N L+ +Y ++RL Sbjct 71 EPFLEVHHLRRLADGGSDTVTNTVALCPNCHREMHYGINKSALVGSMYNKLSRL 124 >ref|YP_002234131.1| putative restriction endonuclease [Burkholderia cenocepacia J2315] emb|CAR55374.1| putative restriction endonuclease [Burkholderia cenocepacia J2315] Length=242 Score = 117 bits (293), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 54/111 (48%), Positives = 68/111 (61%), Gaps = 0/111 (0%) Query 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224 L K ++ P G+ P RDP VKAW+L Q+ G CE C + APF DG PY Sbjct 129 LKKPQIAPPPGNASPEATRATVTQIRRDPSVKAWVLAQANGTCECCSRPAPFKGADGLPY 188 Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 LEVHHV L+ G D N VA+CPNCHRELHY ++A++L+E LY + RL Sbjct 189 LEVHHVRKLAERGPDLVSNTVAVCPNCHRELHYGESARQLVERLYARLPRL 239 >ref|YP_001359725.1| 5-methylcytosine-specific restriction enzyme A [Sulfurovum sp. NBC37-1] dbj|BAF73368.1| 5-methylcytosine-specific restriction enzyme A [Sulfurovum sp. NBC37-1] Length=225 Score = 115 bits (287), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 55/129 (42%), Positives = 77/129 (59%), Gaps = 5/129 (3%) Query 148 LSQPTDDESLLNMRVSKLIKKTLS-QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGI 206 LS+P V KL+ K L +P+ +P + Y RDP + AW+L +KGI Sbjct 98 LSEPVS----FQAEVDKLVHKKLQDKPKAVLEPKRYDIAITKYDRDPQIVAWVLMNAKGI 153 Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIE 266 CE C K APF +DG P+LEVHH+ L+ G+D+ N +A+CPNCHRELHY +N L+ Sbjct 154 CECCNKEAPFVKDDGVPFLEVHHLRRLADDGSDSITNAIAICPNCHRELHYGQNKDILLT 213 Query 267 MLYVNINRL 275 +Y ++RL Sbjct 214 TIYSQVSRL 222 >ref|ZP_01226771.1| putative 5-methylcytosine-specific restriction enzyme [Aurantimonas manganoxydans SI85-9A1] gb|EAS50645.1| putative 5-methylcytosine-specific restriction enzyme [Aurantimonas manganoxydans SI85-9A1] Length=125 Score = 114 bits (286), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 53/117 (45%), Positives = 75/117 (64%), Gaps = 1/117 (0%) Query 158 LNMRVSKL-IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF 216 L RVS+L + T++ P+G +P R V++RDP VKA++L+++ GICE C APF Sbjct 3 LERRVSRLSARATIAFPKGIVQPKHTTRTTIVFLRDPGVKAYVLRRAGGICEACDFPAPF 62 Query 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273 G +LEVHH+ PL+ GG+D N VALCPNCHR +H++ +A + E LY I Sbjct 63 KTALGGDFLEVHHLKPLAEGGSDRAQNAVALCPNCHRAMHHASDAGQRTERLYAKIG 119 >gb|EGD03908.1| 5-methylcytosine-specific restriction enzyme A [Burkholderia sp. TJI49] Length=237 Score = 114 bits (286), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 52/115 (45%), Positives = 72/115 (62%), Gaps = 0/115 (0%) Query 161 RVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND 220 +V++L K +P GS+ P + VRDP VKAW+L+++ G CE C + APF D Sbjct 120 KVARLRKTLKQRPAGSKTPQKTTSTTTSIVRDPHVKAWVLERANGTCEACDQPAPFIGAD 179 Query 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 G P+LEVHH+ L+ G+DT N VA+CPNCHR LH+S+ A+ E LY + L Sbjct 180 GFPFLEVHHLRRLADDGSDTPTNAVAVCPNCHRRLHFSEIARAYRETLYEKVAEL 234 >ref|ZP_02373776.1| HNH endonuclease [Burkholderia thailandensis TXDOH] Length=214 Score = 110 bits (274), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 51/111 (45%), Positives = 73/111 (65%), Gaps = 2/111 (1%) Query 166 IKKTLSQ-PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224 I+KTL + P+G++ P +VRD VKAW+L+++K CE C + APF +G P+ Sbjct 102 IRKTLDERPDGNKAPGTATSTTTSFVRDLKVKAWVLKRAKDNCEACDQPAPFSGANG-PF 160 Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 LEVHH+ L+ GG+DT N VA+CPNCHR LH+SK+A+ E +Y + L Sbjct 161 LEVHHLRKLADGGSDTVTNAVAVCPNCHRRLHFSKDARAYRETIYEKVTEL 211 >ref|YP_350025.1| HNH endonuclease [Pseudomonas fluorescens Pf0-1] gb|ABA76034.1| putative 5-methylcytosine-specific restriction enzyme [Pseudomonas fluorescens Pf0-1] Length=237 Score = 104 bits (259), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 43/82 (52%), Positives = 56/82 (68%), Gaps = 0/82 (0%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VK W+L++S+GICE CG+ APF DG P+LEVHH+ L +GG D T N VALCPNCHR Sbjct 154 VKKWVLKRSQGICEGCGQKAPFQDADGKPFLEVHHLKHLVNGGTDRTSNAVALCPNCHRR 213 Query 255 LHYSKNAKELIEMLYVNINRLQ 276 HYS + +E Y ++ L+ Sbjct 214 CHYSSDKEEFTAKFYRSVEGLE 235 >ref|ZP_04240702.1| HNH nuclease [Bacillus cereus Rock1-15] gb|EEL27596.1| HNH nuclease [Bacillus cereus Rock1-15] Length=350 Score = 103 bits (258), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 57/111 (51%), Positives = 67/111 (60%), Gaps = 10/111 (9%) Query 155 ESLLNMRVSK-------LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207 ES L +RV K K L Q E + VEV Q Y R+P V A IL+++ G C Sbjct 241 ESNLEIRVEKSRNIDSSKRKNRLEQAEKIPEVVEVVTTQ--YKRNPDVIAEILERANGYC 298 Query 208 ENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 E CG+ APF DG PYLEVHHV+PLS GG DT +N ALCPNCHR+ HY Sbjct 299 EECGQEAPFKRTKDGTPYLEVHHVVPLSEGGEDTVENATALCPNCHRKAHY 349 >ref|ZP_02890149.1| HNH endonuclease [Burkholderia ambifaria IOP40-10] gb|EDT04242.1| HNH endonuclease [Burkholderia ambifaria IOP40-10] Length=244 Score = 100 bits (250), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 45/82 (54%), Positives = 59/82 (71%), Gaps = 1/82 (1%) Query 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGG 237 P +V+ + +VYVR+P V A +L+++KG CE C K APF G+ PYLEVHH L+ GG Sbjct 161 PKKVQVVTQVYVRNPDVVADVLERAKGACERCTKPAPFVRRRGDAPYLEVHHRKQLADGG 220 Query 238 ADTTDNCVALCPNCHRELHYSK 259 DT +N +ALCPNCHRE+HY K Sbjct 221 EDTVENAIALCPNCHREMHYGK 242 >ref|ZP_04111523.1| HNH nuclease [Bacillus thuringiensis serovar monterrey BGSC 4AJ1] gb|EEM56742.1| HNH nuclease [Bacillus thuringiensis serovar monterrey BGSC 4AJ1] Length=350 Score = 100 bits (250), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 45/85 (52%), Positives = 58/85 (68%), Gaps = 1/85 (1%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIP 232 + +RKP VE + Y R+P V A +L+++ G CE C + APF DG PYLEVHHVIP Sbjct 265 KAARKPDVVEVVTTQYKRNPDVIAEVLERANGYCEECKQEAPFKRAKDGTPYLEVHHVIP 324 Query 233 LSSGGADTTDNCVALCPNCHRELHY 257 L+ GG D+ +N V LCPNCHR+ HY Sbjct 325 LAQGGEDSVENAVGLCPNCHRKAHY 349 >ref|ZP_04081906.1| HNH nuclease [Bacillus thuringiensis serovar pulsiensis BGSC 4CC1] gb|EEM86379.1| HNH nuclease [Bacillus thuringiensis serovar pulsiensis BGSC 4CC1] Length=350 Score = 100 bits (250), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 45/85 (52%), Positives = 58/85 (68%), Gaps = 1/85 (1%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIP 232 + +RKP VE + Y R+P V A +L+++ G CE C + APF DG PYLEVHHVIP Sbjct 265 KAARKPDVVEVVTTQYKRNPDVIAEVLERANGYCEECKQEAPFKRAKDGTPYLEVHHVIP 324 Query 233 LSSGGADTTDNCVALCPNCHRELHY 257 L+ GG D+ +N V LCPNCHR+ HY Sbjct 325 LAQGGEDSVENAVGLCPNCHRKAHY 349 >ref|YP_003259158.1| HNH endonuclease [Pectobacterium wasabiae WPP163] gb|ACX87551.1| HNH endonuclease [Pectobacterium wasabiae WPP163] Length=240 Score = 99.8 bits (247), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 49/115 (42%), Positives = 68/115 (59%), Gaps = 14/115 (12%) Query 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 E+ + SQ T E ++ VS P E + K++VR+P V A +L ++ Sbjct 138 EVRKASQLTSKERKQHLAVSNF-------------PEMKEVITKIFVRNPYVVAEVLHRA 184 Query 204 KGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 +G CE C +NAPF DG PYLEVHH +PLS GG DT +N +A+CPNCHR+ H+ Sbjct 185 QGKCELCKRNAPFLRGKDGTPYLEVHHCVPLSQGGEDTVENAIAVCPNCHRQAHF 239 >ref|ZP_06898418.1| 5-methylcytosine-specific restriction enzyme A [Roseomonas cervicalis ATCC 49957] gb|EFH09883.1| 5-methylcytosine-specific restriction enzyme A [Roseomonas cervicalis ATCC 49957] Length=279 Score = 98.6 bits (244), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 53/130 (40%), Positives = 77/130 (59%), Gaps = 13/130 (10%) Query 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR---------KPVEVERLQK-VYVRDPM 194 LS S+ DES N+ I+ ++S+ R +PV + +Q V+ RDP Sbjct 145 LSIFSEYIFDES--NLDFQSKIQNSMSESSSIRLERIRSKEKQPVRRKIVQTTVFERDPD 202 Query 195 VKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 + A L Q++G C++C + APF DG PYLEVHH++PLS GG D+ DN ALCPNCHR Sbjct 203 IVAEALFQARGHCQSCKQPAPFRRFADGRPYLEVHHIVPLSEGGPDSLDNVTALCPNCHR 262 Query 254 ELHYSKNAKE 263 ++H+ A++ Sbjct 263 DMHFGPKARK 272 >ref|YP_003332055.1| HNH endonuclease [Dickeya dadantii Ech586] gb|ACZ75350.1| HNH endonuclease [Dickeya dadantii Ech586] Length=245 Score = 98.2 bits (243), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 57/131 (43%), Positives = 75/131 (57%), Gaps = 17/131 (12%) Query 140 IIRGELSELSQPTDDESL---LNMRVSKLI---------KKTLSQPEGSRKPVEVERLQK 187 II SELS+ E+L N++V+K I + + S +K +++E Sbjct 115 IIEFYESELSKTDSFENLTTEFNIQVNKSIADNQRSRQERLSTSPKYPQKKSLQIE---- 170 Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVA 246 ++R+P V A +L ++ G CE C NAPF D PYLEVHH PLS GGADT DN +A Sbjct 171 FFIRNPDVVAEVLLRANGKCERCCSNAPFLRKKDNTPYLEVHHKTPLSEGGADTVDNAIA 230 Query 247 LCPNCHRELHY 257 LCPNCHR LHY Sbjct 231 LCPNCHRYLHY 241 >ref|ZP_04309075.1| HNH nuclease [Bacillus cereus 172560W] gb|EEK59210.1| HNH nuclease [Bacillus cereus 172560W] Length=350 Score = 97.8 bits (242), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 42/85 (49%), Positives = 57/85 (67%), Gaps = 1/85 (1%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIP 232 + RKP VE + Y R+P V A +L+++ G CE C + APF DG PYLEVHHV+P Sbjct 265 QAVRKPEVVEVVTSQYKRNPDVIAEVLERANGYCEECKQEAPFKRAKDGTPYLEVHHVVP 324 Query 233 LSSGGADTTDNCVALCPNCHRELHY 257 L+ GG D+ +N V +CPNCHR+ H+ Sbjct 325 LAQGGEDSVENAVGMCPNCHRKAHF 349 >gb|ECQ33615.1| hypothetical protein GOS_6056978 [marine metagenome] Length=167 Score = 97.4 bits (241), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 47/124 (37%), Positives = 75/124 (60%), Gaps = 2/124 (1%) Query 154 DESLLNMRVSKLIKKTL-SQPEGSRKPVE-VERLQKVYVRDPMVKAWILQQSKGICENCG 211 D+ + ++ ++K + ++P+G P + + +V D VKA++LQ + GICE C Sbjct 41 DQYEIEEEINTIVKTQIQAKPKGQEVPTKKLLAGTTSFVPDLEVKAFVLQNANGICEFCD 100 Query 212 KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVN 271 K APF G PYL+VHHV S GG+D +N +A+CPNCH H+S++ + ++E Y Sbjct 101 KQAPFVTKKGRPYLDVHHVKWRSEGGSDKVENAIAVCPNCHMRFHHSEDKEVVLEKAYSK 160 Query 272 INRL 275 I+RL Sbjct 161 IDRL 164 >ref|YP_387711.1| HNH nuclease [Desulfovibrio desulfuricans subsp. desulfuricans str. G20] gb|ABB38016.1| HNH nuclease [Desulfovibrio desulfuricans subsp. desulfuricans str. G20] Length=260 Score = 97.4 bits (241), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 44/75 (58%), Positives = 52/75 (69%), Gaps = 1/75 (1%) Query 184 RLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGGADTTD 242 R Q V+ R P+V A +L ++ G CE CG APF N PYLEVHHV PL+ GGADT Sbjct 173 REQAVFRRSPVVAARVLLRAGGFCECCGAPAPFVSRADNLPYLEVHHVRPLAEGGADTPA 232 Query 243 NCVALCPNCHRELHY 257 NC+ALCPNCHR+ HY Sbjct 233 NCMALCPNCHRQFHY 247 >gb|EBI36964.1| hypothetical protein GOS_9104437 [marine metagenome] Length=190 Score = 97.4 bits (241), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 50/103 (48%), Positives = 66/103 (64%), Gaps = 7/103 (6%) Query 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYL 225 I KT+ QP GSR + +V+ R P +K + L+++ G CE C + APF +G PYL Sbjct 83 IDKTVKQP-GSR-----DSTTRVFQRSPFIKDYTLRRANGRCELCSQKAPFNKPNGEPYL 136 Query 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268 EVHH+ L+ GG DT +N VALCPNCHR +H S N K IE+L Sbjct 137 EVHHIKHLADGGEDTIENAVALCPNCHRMMH-SLNRKSDIEIL 178 >ref|ZP_06157518.1| HNH nuclease [Photobacterium damselae subsp. damselae CIP 102761] gb|EEZ39959.1| HNH nuclease [Photobacterium damselae subsp. damselae CIP 102761] Length=278 Score = 97.1 bits (240), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 44/85 (51%), Positives = 60/85 (70%), Gaps = 1/85 (1%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIP 232 + ++KP + R+ K Y R+P + A L ++ GICE CG APF ++G PYLEVHH+IP Sbjct 193 KANKKPQLISRVVKDYQRNPDIVAEALIRAAGICEACGCQAPFNKKSNGEPYLEVHHLIP 252 Query 233 LSSGGADTTDNCVALCPNCHRELHY 257 LS GG D+ DN +LCPNCHR+LH+ Sbjct 253 LSKGGEDSLDNVQSLCPNCHRKLHF 277 >ref|ZP_07043201.1| HNH endonuclease [Comamonas testosteroni S44] gb|EFI63106.1| HNH endonuclease [Comamonas testosteroni S44] Length=248 Score = 97.1 bits (240), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 46/92 (50%), Positives = 62/92 (67%), Gaps = 3/92 (3%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYL 225 +K LS S++P V +L K++ R+P V A +L +KGIC +CG PF +DG+ YL Sbjct 154 RKRLS--SASKRPKRVAKLVKLFQRNPDVVAEVLYLAKGICGSCGSRGPFNRRSDGSLYL 211 Query 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 EVHH IPL+ GG DT +N +ALCPNCHR H+ Sbjct 212 EVHHKIPLAEGGDDTVENAIALCPNCHRNKHF 243 >gb|ECF76608.1| hypothetical protein GOS_4933757 [marine metagenome] Length=237 Score = 95.9 bits (237), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 42/84 (50%), Positives = 57/84 (67%), Gaps = 1/84 (1%) Query 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIPL 233 S+ P V +V+ R+P V A +L ++ GICE C ++APF D PYLEVHH+ L Sbjct 153 ASKIPARVSVSTEVFRRNPDVVAEVLLRANGICERCKQDAPFLRAKDQTPYLEVHHIKQL 212 Query 234 SSGGADTTDNCVALCPNCHRELHY 257 ++GG DT +N +ALCPNCHRELH+ Sbjct 213 AAGGEDTVENALALCPNCHRELHF 236 >ref|YP_003726057.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] gb|ADI73261.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] Length=475 Score = 95.1 bits (235), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 42/98 (42%), Positives = 59/98 (60%), Gaps = 0/98 (0%) Query 159 NMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYL 218 ++ + +L ++ + S KP E + RDP + + +KG+C+ CG NAPFY Sbjct 357 DLSIEELKQRVRQSKKNSTKPDRREVNTETPKRDPYISELAKRMAKGVCQLCGNNAPFYD 416 Query 219 NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 GNPYLE HH+I +S G DT DN VALC NCHR++H Sbjct 417 RGGNPYLETHHIIRVSKDGDDTIDNVVALCANCHRKMH 454 >ref|ZP_03781850.1| hypothetical protein RUMHYD_01286 [Blautia hydrogenotrophica DSM 10507] gb|EEG49782.1| hypothetical protein RUMHYD_01286 [Blautia hydrogenotrophica DSM 10507] Length=270 Score = 94.4 bits (233), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 48/127 (37%), Positives = 79/127 (62%), Gaps = 6/127 (4%) Query 145 LSELSQPTDDESLLNMRVSKLIKKT-LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 + EL +P +D +L + +L +++ +S+ E R+P VE VY RDP +K I + + Sbjct 135 VRELDEP-EDRALSQLSSRELERRSKISRRE--RRPKTVE--TTVYYRDPYLKELIKRIA 189 Query 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263 +G C+ CG +APF + PYLE HH+ L+ GG DT DN VA+CPNCHR +H ++ Sbjct 190 EGKCQFCGADAPFLDRNHEPYLEEHHIKRLADGGTDTIDNIVAICPNCHRRMHVLNREED 249 Query 264 LIEMLYV 270 ++++ ++ Sbjct 250 ILKLRFI 256 >ref|YP_001023049.1| hypothetical protein Mpe_B0033 [Methylibium petroleiphilum PM1] gb|ABM96814.1| hypothetical protein Mpe_B0033 [Methylibium petroleiphilum PM1] Length=220 Score = 94.4 bits (233), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 44/85 (51%), Positives = 54/85 (63%), Gaps = 1/85 (1%) Query 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPL 233 G KP V V++R+P V A +L ++ G CE C ++APF DG PYLEVHH PL Sbjct 136 GQAKPERVIVQTTVFMRNPAVAAEVLLRANGHCELCRQSAPFKRRKDGTPYLEVHHRKPL 195 Query 234 SSGGADTTDNCVALCPNCHRELHYS 258 S GG DT N +ALCPNCHR HY+ Sbjct 196 SDGGNDTVQNAIALCPNCHRRAHYA 220 >ref|ZP_03029796.1| HNH endonuclease [Escherichia coli B7A] gb|EDV61681.1| HNH endonuclease [Escherichia coli B7A] Length=241 Score = 94.0 bits (232), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 43/97 (44%), Positives = 63/97 (64%), Gaps = 1/97 (1%) Query 161 RVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND 220 ++S + +K + E S+ P +E +VY R P V A +L ++ G C+ C ++APF D Sbjct 136 KLSSVERKQILATE-SKIPELIEVTTRVYKRSPYVVAEVLLRANGKCQYCKRDAPFLKED 194 Query 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 G P+LEVHH+ LS GG D+ +N +ALCPNCHR+ HY Sbjct 195 GTPFLEVHHIEWLSKGGEDSVENAIALCPNCHRQAHY 231 >ref|ZP_07151494.1| HNH endonuclease domain protein [Escherichia coli MS 21-1] ref|ZP_08374394.1| 5-methylcytosine-specific restriction enzyme A (EcoKMcrA) [Escherichia coli TA280] gb|EFK21787.1| HNH endonuclease domain protein [Escherichia coli MS 21-1] gb|EGI40296.1| 5-methylcytosine-specific restriction enzyme A (EcoKMcrA) [Escherichia coli TA280] Length=241 Score = 94.0 bits (232), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 43/97 (44%), Positives = 63/97 (64%), Gaps = 1/97 (1%) Query 161 RVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND 220 ++S + +K + E S+ P +E +VY R P V A +L ++ G C+ C ++APF D Sbjct 136 KLSSVERKQILATE-SKIPELIEVTTRVYKRSPYVVAEVLLRANGKCQYCKRDAPFLKED 194 Query 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 G P+LEVHH+ LS GG D+ +N +ALCPNCHR+ HY Sbjct 195 GTPFLEVHHIEWLSKGGEDSVENAIALCPNCHRQAHY 231 >ref|ZP_08129831.1| 5-methylcytosine-specific restriction enzyme A (EcoKMcrA) [Clostridium sp. D5] gb|EGB92769.1| 5-methylcytosine-specific restriction enzyme A (EcoKMcrA) [Clostridium sp. D5] Length=268 Score = 93.6 bits (231), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 40/78 (51%), Positives = 52/78 (66%), Gaps = 0/78 (0%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 VY R+P VK + ++G C+ C K APFY D PYLE HHV L+ GG+DT DN VAL Sbjct 155 VYYRNPYVKEMVKHIAEGKCQMCSKEAPFYDKDSKPYLEEHHVNRLADGGSDTMDNVVAL 214 Query 248 CPNCHRELHYSKNAKELI 265 CPNCHR++H + ++ I Sbjct 215 CPNCHRKIHVLNDEQDTI 232 >ref|ZP_05920085.1| 5-methylcytosine-specific restriction enzyme A [Pasteurella dagmatis ATCC 43325] gb|EEX50323.1| 5-methylcytosine-specific restriction enzyme A [Pasteurella dagmatis ATCC 43325] Length=200 Score = 92.8 bits (229), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 48/115 (41%), Positives = 67/115 (58%), Gaps = 11/115 (9%) Query 158 LNMRVSKLIKKTL-SQPEGSRKPVEVERLQKV---------YVRDPMVKAWILQQSKGIC 207 + K +KK L PE +K ++ ++++K + RDP V A +L Q+ G+C Sbjct 86 FDSEFDKKVKKALHDSPEKRQKRLDRKKIKKPSYSFVKIRQFHRDPDVVAEVLYQANGVC 145 Query 208 ENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNA 261 C K APF D PYLEVHH IPLS G D+ NC+ALCPNCHR++H+ N+ Sbjct 146 GACKKPAPFNRKVDNMPYLEVHHKIPLSQNGDDSVSNCIALCPNCHRKIHFGNNS 200 >gb|EDA78595.1| hypothetical protein GOS_1937529 [marine metagenome] Length=105 Score = 92.0 bits (227), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 42/96 (43%), Positives = 61/96 (63%), Gaps = 5/96 (5%) Query 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS 235 S+ P +VY R P V A +L ++ G C++C ++APF DG P+LEVHH+ LS Sbjct 14 SKTPELTVVTTRVYKRSPYVVAEVLLRANGKCQSCNRDAPFVKEDGTPFLEVHHIEWLSK 73 Query 236 GGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVN 271 GG D+ +N +ALCPNCHR+ HY ++E++ VN Sbjct 74 GGEDSVENAIALCPNCHRQAHYG-----VLELVAVN 104 >ref|YP_004189288.1| HNH endonuclease [Vibrio vulnificus MO6-24/O] gb|ADV87085.1| HNH endonuclease [Vibrio vulnificus MO6-24/O] Length=235 Score = 91.7 bits (226), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 44/128 (34%), Positives = 72/128 (56%), Gaps = 12/128 (9%) Query 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRK---------PVEVERLQKVYV 190 I+ ++ PT ++ + + + I+++ + G+RK P ++ + Sbjct 109 ILTSNDEQVGSPTSEQ--IQLELEDAIERSFNDTPGNRKKRLFSSNKRPERIQTTTHTFR 166 Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R+P V +L ++ G+CE C + APF + DG PYLEVHH+ L+ GG D+ +N ALCP Sbjct 167 RNPDVIVEVLLRADGVCERCKQQAPFSRSRDGTPYLEVHHIKRLADGGDDSVENAQALCP 226 Query 250 NCHRELHY 257 NCHRELH+ Sbjct 227 NCHRELHF 234 >ref|ZP_00989258.1| putative restriction endonuclease [Vibrio splendidus 12B01] gb|EAP95853.1| putative restriction endonuclease [Vibrio splendidus 12B01] Length=273 Score = 91.3 bits (225), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 52/135 (38%), Positives = 72/135 (53%), Gaps = 10/135 (7%) Query 131 IYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTL-SQPEGSRKPVEVERLQKVY 189 I S +I + S L++PT +SL +R L L + P+ E+L V Sbjct 132 IVPQSVSNTIQTPKASYLTKPTKSKSLKQLRDIALASTPLQADPK--------EQLTHVK 183 Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R +K + +++ GICE CG +PF G PYLEVHH+ L+ GGAD +N +ALCP Sbjct 184 YRSEAIKLYAKKRANGICEGCGVPSPFETKSG-PYLEVHHLTRLADGGADCPENVIALCP 242 Query 250 NCHRELHYSKNAKEL 264 CHRE HYS A + Sbjct 243 TCHREAHYSVGAADF 257 >ref|YP_001528806.1| HNH endonuclease [Desulfococcus oleovorans Hxd3] gb|ABW66729.1| HNH endonuclease [Desulfococcus oleovorans Hxd3] Length=303 Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 41/97 (42%), Positives = 65/97 (67%), Gaps = 3/97 (3%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVI 231 P G +P ++ R+ Y RDP +++++++++KG CE CG+ F ++DG N YLE HH+I Sbjct 201 PPGISEPEKISRMSPSYSRDPKIRSFVIKRAKGRCEYCGEQG-FLMSDGQNYYLEAHHII 259 Query 232 PLSSGGADTTDNCVALCPNCHRELHYSKNAKEL-IEM 267 L+ G DT +N +ALCP HRE H+ N ++L +EM Sbjct 260 ALADEGEDTVENVIALCPKHHREAHFGANKEKLEVEM 296 >ref|ZP_02432833.1| hypothetical protein CLOSCI_03091 [Clostridium scindens ATCC 35704] gb|EDS05723.1| hypothetical protein CLOSCI_03091 [Clostridium scindens ATCC 35704] Length=277 Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 42/80 (52%), Positives = 56/80 (70%), Gaps = 1/80 (1%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 YVRD V + +++ GIC+ C K APF DGNP+LE HH+I L+ GGAD+ +N VALC Sbjct 191 YVRDRYVSEYAKRRAHGICQLCDKPAPFSDCDGNPFLETHHIIWLADGGADSIENTVALC 250 Query 249 PNCHRELHYSKNAKELIEML 268 PNCHR++H + N E +E L Sbjct 251 PNCHRKMH-TLNLSEDVEKL 269 >gb|ECT50358.1| hypothetical protein GOS_5713549 [marine metagenome] Length=262 Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 45/118 (38%), Positives = 67/118 (56%), Gaps = 5/118 (4%) Query 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 MR+ +L + ++ GS+ V R R ++K + +SKGICE C NAPF Sbjct 147 MRLRELAYEGANETPGSKISETVRR-----ERREIIKIYAHDRSKGICEACESNAPFISR 201 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 +G P+LEVHH+ PL+ GG D N A+CPNCHR + Y + +E + L I+ L++ Sbjct 202 NGKPFLEVHHIKPLAEGGVDHPKNVAAICPNCHRRIDYGMDGQEFNQSLKGKIHALEE 259 >ref|YP_001339470.1| HNH endonuclease [Marinomonas sp. MWYL1] gb|ABR69535.1| HNH endonuclease [Marinomonas sp. MWYL1] Length=240 Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 40/71 (56%), Positives = 51/71 (71%), Gaps = 1/71 (1%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVA 246 VY R+P V L+++ G+CE CGK APF + DG+PYLEVHH+ L+ G DT +N A Sbjct 169 VYQRNPDVITETLERAAGVCERCGKGAPFIRSKDGSPYLEVHHIQRLADNGPDTLENTKA 228 Query 247 LCPNCHRELHY 257 LCPNCHRELH+ Sbjct 229 LCPNCHRELHF 239 >ref|YP_001129610.1| HNH endonuclease [Chlorobium phaeovibrioides DSM 265] gb|ABP36108.1| HNH endonuclease [Chlorobium phaeovibrioides DSM 265] Length=222 Score = 90.5 bits (223), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 46/120 (38%), Positives = 67/120 (55%), Gaps = 10/120 (8%) Query 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198 ++I E +E+++ D S+ R +++ ++P Y R+P + Sbjct 111 ALIETETAEIAKSRTDTSV--ARNERILN-------AEKRPKRQRVYSYTYQRNPDIVVE 161 Query 199 ILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 L +++G CENC APF +DG P+LEVHH+ LS GG DT +N VALCPNCHRE HY Sbjct 162 ALHRAEGFCENCKNPAPFKRASDGTPFLEVHHIRSLSDGGEDTLENVVALCPNCHREKHY 221 >gb|EBQ48256.1| hypothetical protein GOS_7744649 [marine metagenome] Length=222 Score = 90.5 bits (223), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 36/70 (51%), Positives = 49/70 (70%), Gaps = 0/70 (0%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 V ++ +Q+SKGICE+C APF +G PYLEVHH+IP+S GG D +N A+CPNCHR Sbjct 135 VHSYAIQRSKGICESCETPAPFETRNGTPYLEVHHLIPISKGGPDHPENVAAVCPNCHRR 194 Query 255 LHYSKNAKEL 264 SK++ + Sbjct 195 TEKSKDSDQF 204 >ref|ZP_04634188.1| Restriction endonuclease [Yersinia frederiksenii ATCC 33641] gb|EEQ13193.1| Restriction endonuclease [Yersinia frederiksenii ATCC 33641] Length=238 Score = 90.1 bits (222), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 37/70 (52%), Positives = 51/70 (72%), Gaps = 0/70 (0%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 + R+P+V A +L + G C++C ++APF DG PYLEVHHV L++GG D+ +N +AL Sbjct 158 TFKRNPLVVAEVLALAGGKCQSCLRDAPFKREDGRPYLEVHHVEWLANGGEDSVENAIAL 217 Query 248 CPNCHRELHY 257 CPNCHRE HY Sbjct 218 CPNCHREAHY 227 >ref|ZP_01667048.1| HNH endonuclease [Thermosinus carboxydivorans Nor1] gb|EAX47151.1| HNH endonuclease [Thermosinus carboxydivorans Nor1] Length=275 Score = 89.7 bits (221), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 43/100 (43%), Positives = 59/100 (59%), Gaps = 5/100 (5%) Query 157 LLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF 216 L N ++K K++ S+ R V +Y R+ V + +++ GIC+ C + APF Sbjct 163 LDNETLAKRAKESQSEKTSVRNAVTT-----IYERNAYVSEYAKRRANGICQLCEREAPF 217 Query 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 DG PYLE HH+ LS GG DT DN VALCPNCHR++H Sbjct 218 KNKDGEPYLETHHIEWLSRGGTDTLDNTVALCPNCHRKMH 257 >ref|YP_002139592.1| HNH endonuclease [Geobacter bemidjiensis Bem] gb|ACH39796.1| HNH endonuclease [Geobacter bemidjiensis Bem] Length=233 Score = 89.7 bits (221), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 45/128 (35%), Positives = 68/128 (53%), Gaps = 0/128 (0%) Query 150 QPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209 +PT +E ++ S I P+G +P Y RD V+A+++ ++KG CE Sbjct 95 EPTMNEEKVHEFASNAINDLDEIPQGVAEPERSSHTTSSYARDHKVRAYVIARAKGTCEY 154 Query 210 CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269 CG+ N + YLE HHVI L+ G DT DN +ALCP H+E H+ N E+ E + Sbjct 155 CGELGFLMSNGKSYYLEAHHVIALADEGRDTPDNVIALCPKHHKEAHFGINRDEIEEEMM 214 Query 270 VNINRLQK 277 + ++ L K Sbjct 215 IFLSTLSK 222 >ref|ZP_08559105.1| HNH endonuclease [Halorhabdus tiamatea SARL4B] gb|EGM36003.1| HNH endonuclease [Halorhabdus tiamatea SARL4B] Length=150 Score = 89.4 bits (220), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 42/94 (44%), Positives = 55/94 (58%), Gaps = 1/94 (1%) Query 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234 G R+ E Q Y R +VK + L+ + G+C+ G APF DG P+LEVH++ S Sbjct 33 GDRRTT-TESSQTQYRRPEIVKQYALRVADGVCQGGGDEAPFLDEDGEPFLEVHYLHRRS 91 Query 235 SGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268 GGAD DN VALCPNCHR +HY +N + L Sbjct 92 DGGADHPDNVVALCPNCHRRVHYEQNGDAFNQQL 125 >emb|CBL27586.1| Restriction endonuclease [Ruminococcus torques L2-14] Length=324 Score = 89.0 bits (219), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 41/103 (39%), Positives = 65/103 (63%), Gaps = 3/103 (2%) Query 178 KPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237 KP + V+ RDP++ A + +++ G C+ CG+ APF +G PYLE HH++ L+ GG Sbjct 221 KPGKSRVNTTVFNRDPVIAAAVKERANGQCDLCGQPAPFNNANGFPYLEEHHLVRLADGG 280 Query 238 ADTTDNCVALCPNCHRELHY---SKNAKELIEMLYVNINRLQK 277 D+ DN VALCPNCHR++H ++ + L + + V +N + K Sbjct 281 DDSIDNAVALCPNCHRKMHVVNDERDTETLKKRILVYVNAMNK 323 >ref|YP_003812225.1| probable endonuclease [gamma proteobacterium HdN1] emb|CBL46584.1| probable endonuclease [gamma proteobacterium HdN1] Length=285 Score = 89.0 bits (219), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 39/73 (53%), Positives = 49/73 (67%), Gaps = 1/73 (1%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 VY R+P V +L ++KG+CE C APF D PYLEVHH + L+ GG DT +N VA Sbjct 210 VYERNPYVVVEVLNRAKGMCERCKSQAPFKRRKDNTPYLEVHHRVRLADGGEDTVENAVA 269 Query 247 LCPNCHRELHYSK 259 LCPNCHR LH+ + Sbjct 270 LCPNCHRLLHFGR 282 >ref|ZP_01063162.1| HNH endonuclease [Vibrio sp. MED222] gb|EAQ55841.1| HNH endonuclease [Vibrio sp. MED222] Length=273 Score = 89.0 bits (219), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 47/121 (38%), Positives = 67/121 (55%), Gaps = 8/121 (6%) Query 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 ++S L++PT +SL +R L L K E+L V R +K + +++ Sbjct 145 KVSYLTKPTKSKSLKQLRDIALASTPL-------KADPKEQLTHVKYRSEAIKLYAKKRA 197 Query 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263 G+CE CG +PF G PYLEVHH+ L+ GGAD +N +ALCP CHR+ HYS A + Sbjct 198 NGLCEGCGVPSPFETKSG-PYLEVHHLTRLADGGADCPENVIALCPTCHRKAHYSVEAAD 256 Query 264 L 264 Sbjct 257 F 257 >ref|ZP_05430896.1| HNH endonuclease [Clostridium thermocellum DSM 2360] gb|EEU00230.1| HNH endonuclease [Clostridium thermocellum DSM 2360] gb|ADU75390.1| HNH endonuclease [Clostridium thermocellum DSM 1313] Length=276 Score = 89.0 bits (219), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 35/69 (50%), Positives = 50/69 (72%), Gaps = 0/69 (0%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 V++RD V + +++ G+C+ CG+ APF +G PYLE HH+ LS GG+DT +N VAL Sbjct 187 VFIRDAFVAEYAKRRANGVCQLCGQKAPFNNKEGIPYLECHHIEWLSEGGSDTIENTVAL 246 Query 248 CPNCHRELH 256 CPNCHR++H Sbjct 247 CPNCHRKMH 255 >ref|YP_003007474.1| HNH nuclease [Aggregatibacter aphrophilus NJ8700] gb|ACS97387.1| HNH nuclease [Aggregatibacter aphrophilus NJ8700] Length=194 Score = 88.6 bits (218), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 43/85 (50%), Positives = 57/85 (67%), Gaps = 5/85 (5%) Query 176 SRKPVE--VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVIP 232 S+ P++ +E LQ + R+P V A +L ++ G CE C K APF PYLEVHH+IP Sbjct 111 SKHPIKKIIEVLQ--FQRNPDVVAEVLVRANGYCEKCKKPAPFIRKANLQPYLEVHHIIP 168 Query 233 LSSGGADTTDNCVALCPNCHRELHY 257 LS G DT +NC+ALCPNCHR+ H+ Sbjct 169 LSKDGEDTVENCMALCPNCHRQEHF 193 >ref|YP_004378892.1| putative restriction endonuclease [Pseudomonas mendocina NK-01] gb|AEB57140.1| putative restriction endonuclease [Pseudomonas mendocina NK-01] Length=244 Score = 87.8 bits (216), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 47/117 (40%), Positives = 68/117 (58%), Gaps = 8/117 (6%) Query 157 LLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF 216 L + V KL K+ G+R + + +V + + ++KG CE CG+ APF Sbjct 133 LSDTEVEKLAKQQGQAKVGTRTVSATQHQRSAWVAENARR-----RAKGHCELCGEPAPF 187 Query 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY---SKNAKELIEMLYV 270 DG+PYLE HH+ L++GGADT +N VALCPNCHR++H S + K LIE + + Sbjct 188 KRKDGSPYLETHHIEWLANGGADTVENTVALCPNCHRKMHIVNASADQKILIEKVTI 244 >gb|ECM81520.1| hypothetical protein GOS_4910044 [marine metagenome] Length=232 Score = 87.8 bits (216), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 41/78 (52%), Positives = 54/78 (69%), Gaps = 1/78 (1%) Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 R+P V A+ L+++ G CE C + APF ++G PYLEVHH+ L GG D T+N VALCPN Sbjct 147 RNPYVVAYTLRRANGFCELCEQPAPFNKDNGEPYLEVHHIKHLEDGGNDMTENAVALCPN 206 Query 251 CHRELHYSKNAKELIEML 268 CHR +H S N K I++L Sbjct 207 CHRMMH-SLNRKSDIDIL 223 >ref|YP_004307224.1| HNH endonuclease [Clostridium lentocellum DSM 5427] gb|ADZ82026.1| HNH endonuclease [Clostridium lentocellum DSM 5427] Length=392 Score = 87.8 bits (216), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 37/69 (53%), Positives = 49/69 (71%), Gaps = 1/69 (1%) Query 192 DPMVKAWILQQSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 +P+V A L +KG CE CG+ APF DG PYLEVHH+ ++ GG DT DN +ALCPN Sbjct 322 NPVVIATRLALAKGKCEKCGQEAPFISALDGMPYLEVHHIKSIAEGGEDTVDNTIALCPN 381 Query 251 CHRELHYSK 259 CH+E+H+ + Sbjct 382 CHKEIHFGR 390 >gb|ECB05675.1| hypothetical protein GOS_5878671 [marine metagenome] Length=191 Score = 87.4 bits (215), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 37/78 (47%), Positives = 50/78 (64%), Gaps = 0/78 (0%) Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 R +K ++L+++ GICE G+ APF +G P+LEVHH+ LS GG D NC A+ PN Sbjct 102 RSEAIKEYVLKRANGICELTGQKAPFEKENGEPFLEVHHIKRLSDGGIDHPKNCAAITPN 161 Query 251 CHRELHYSKNAKELIEML 268 HRE+H+ N K L E L Sbjct 162 AHREVHFGVNGKTLDEQL 179 >ref|ZP_01741593.1| HNH nuclease [Rhodobacterales bacterium HTCC2150] gb|EBA04046.1| HNH nuclease [Rhodobacterales bacterium HTCC2150] Length=371 Score = 87.4 bits (215), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 48/128 (37%), Positives = 71/128 (55%), Gaps = 8/128 (6%) Query 137 WASIIRGE--LSELSQPTDDESLLNMRVSKLIK-----KTLSQPEGSRKPVEVERLQKVY 189 W +++ LS+L E+ L +V K +K + + + P + + ++ Sbjct 236 WFTLVEWSDGLSDLQSVAAAETSLVEQVQKSLKLDPKARQKRLADAPKLPEKQKATTTIF 295 Query 190 VRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 R+P V A +L ++ G CE C ++APF +DG PYLEVHH IPL+ G D+ DN VALC Sbjct 296 KRNPDVIAEVLFRANGTCEGCRQSAPFDRRSDGTPYLEVHHKIPLAKDGHDSVDNAVALC 355 Query 249 PNCHRELH 256 PNCHR H Sbjct 356 PNCHRREH 363 >ref|ZP_08167033.1| HNH endonuclease domain protein [Turicibacter sp. HGF1] gb|EGC92630.1| HNH endonuclease domain protein [Turicibacter sp. HGF1] Length=297 Score = 87.0 bits (214), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 39/80 (48%), Positives = 52/80 (65%), Gaps = 1/80 (1%) Query 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLSSGG 237 P + + K+Y R+P V L+++ G CE CG APF NP YLEVHH IPLS+GG Sbjct 216 PERITIVSKIYKRNPAVVIATLRRANGYCEKCGCTAPFNRKSDNPPYLEVHHNIPLSNGG 275 Query 238 ADTTDNCVALCPNCHRELHY 257 D +N +A+CPNC+RE H+ Sbjct 276 LDDLENTIAVCPNCYREFHF 295 >ref|ZP_06181860.1| hypothetical protein VMC_32900 [Vibrio alginolyticus 40B] gb|EEZ81858.1| hypothetical protein VMC_32900 [Vibrio alginolyticus 40B] Length=277 Score = 86.3 bits (212), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 48/126 (38%), Positives = 70/126 (55%), Gaps = 8/126 (6%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202 G+ L++PT +SL +R I ++ + K E++ V R +K + ++ Sbjct 144 GKAPYLTKPTKSKSLKQLRD---IATAVTPNDVDVK----EQVAHVRYRSEAIKLYAKKR 196 Query 203 SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262 + GICE C +PF G PYLEVHH+ L+ GGAD +N +ALCP CHR HYS ++K Sbjct 197 ANGICEGCRIGSPFETKAG-PYLEVHHLTRLADGGADCPENVIALCPTCHRRAHYSIDSK 255 Query 263 ELIEML 268 E E L Sbjct 256 EFNEQL 261 >ref|ZP_04220300.1| restriction endonuclease [Bacillus cereus Rock3-44] gb|EEL47987.1| restriction endonuclease [Bacillus cereus Rock3-44] Length=254 Score = 86.3 bits (212), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 55/145 (37%), Positives = 84/145 (57%), Gaps = 7/145 (4%) Query 134 DSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQ-KVYVRD 192 D ++II EL L Q D + R++ K +Q E S V V +Q K + R+ Sbjct 111 DDKASTIINEEL--LKQNYDKKEQKARRLTNEEVKNKAQ-EASSNRVGVRNIQSKTFDRN 167 Query 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P V + + + GIC+ C K APF +G PYLE HH+ LS GG D+ +N VALCPNCH Sbjct 168 PYVTIYAKRWADGICQLCEKPAPFINKEGEPYLETHHIEWLSQGGPDSIENTVALCPNCH 227 Query 253 RELHY--SKNAKE-LIEMLYVNINR 274 +++H S++ K+ L++ ++ NI++ Sbjct 228 KKMHVVDSQDDKDKLLKKVHQNISQ 252 >ref|YP_004156661.1| hnh nuclease [Variovorax paradoxus EPS] gb|ADU38550.1| HNH nuclease [Variovorax paradoxus EPS] Length=282 Score = 85.9 bits (211), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 49/137 (35%), Positives = 74/137 (54%), Gaps = 9/137 (6%) Query 138 ASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKA 197 A + + EL+ +S+P D +L R + + + +R + +Y R +V+ Sbjct 144 ARLEQDELTGISEPLIDLTLDEARRRAIAAAKVDASKDTRHG-----RRTIYERSRIVRD 198 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 ++L+++ GICE C K+APF G+ YLE HH +S GG D ALCP CHRE+HY Sbjct 199 YVLRRASGICELCEKSAPFRRTGGSAYLEPHHTTRVSDGGPDHPQFVAALCPACHREVHY 258 Query 258 SKNA----KELIEMLYV 270 + A KELIE L + Sbjct 259 GEYAQTRNKELIERLLI 275 >ref|ZP_03991369.1| conserved hypothetical protein [Oribacterium sinus F0268] gb|EEJ51392.1| conserved hypothetical protein [Oribacterium sinus F0268] Length=324 Score = 85.5 bits (210), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 38/97 (39%), Positives = 60/97 (61%), Gaps = 4/97 (4%) Query 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEV 227 K + +K EVE +Q R +V + + +++ G+C+ C K APFY G YLE Sbjct 222 KDFDKQHPKKKLTEVEVVQ----RSSLVSSIVKERAAGVCQLCNKPAPFYNKSGEAYLEC 277 Query 228 HHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264 HHV+ ++ GGAD +N VALCPNCHR++H +++++ Sbjct 278 HHVVWIAKGGADEVNNAVALCPNCHRKMHILDDSEDV 314 >gb|ECK58534.1| hypothetical protein GOS_3293689 [marine metagenome] Length=252 Score = 85.5 bits (210), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 46/113 (40%), Positives = 73/113 (64%), Gaps = 3/113 (2%) Query 146 SELSQPTDDESLLNMRVS--KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 SEL++ + + N +S +L+++ S+ +GSRKP + + Y RD V + L ++ Sbjct 121 SELAKTLEKKIKKNKSLSGGELLERIQSK-KGSRKPGKRPTISNSYQRDEDVILYSLLRA 179 Query 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 +GICE C + APF +DG +LEVHH+ L++ G D+ +N VALCPNCHR++H Sbjct 180 QGICELCEQPAPFVKSDGEGFLEVHHIQHLANDGDDSIENTVALCPNCHRKMH 232 >ref|YP_579285.1| HNH endonuclease [Psychrobacter cryohalolentis K5] gb|ABE73801.1| HNH endonuclease [Psychrobacter cryohalolentis K5] Length=282 Score = 85.5 bits (210), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 46/124 (37%), Positives = 65/124 (52%), Gaps = 14/124 (11%) Query 148 LSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEV---ERLQKVYVRDPMVKAWILQQSK 204 +++P+ +SL +R L S P E++Q + R +K + +++ Sbjct 157 VTKPSKGKSLQQLREIAL----------SSTPTHASTQEKIQSIQNRSTAIKLYAKKRAN 206 Query 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264 GICE C + APF G PYLEVHH+ L+ GGAD N +ALCP CHR+ HYS N E Sbjct 207 GICEGCNEIAPFETKSG-PYLEVHHLTRLADGGADLPQNVIALCPTCHRKAHYSLNHLEF 265 Query 265 IEML 268 L Sbjct 266 NNQL 269 >ref|YP_004425314.1| HNH nuclease [Alteromonas macleodii str. 'Deep ecotype'] gb|AEA96316.1| HNH nuclease [Alteromonas macleodii str. 'Deep ecotype'] Length=199 Score = 85.1 bits (209), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 42/79 (53%), Positives = 54/79 (68%), Gaps = 5/79 (6%) Query 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGA 238 VEV LQ R+P V A +L ++KGIC +C APF DG+PYLEVHH+ L+ GG Sbjct 124 VEVSVLQ----RNPDVVAEVLFRAKGICGSCKNPAPFSRRKDGSPYLEVHHIQQLAHGGE 179 Query 239 DTTDNCVALCPNCHRELHY 257 DT +N +ALCPNCHR+ H+ Sbjct 180 DTLENAIALCPNCHRQKHF 198 >gb|EDI01692.1| hypothetical protein GOS_502793 [marine metagenome] Length=116 Score = 85.1 bits (209), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 39/89 (43%), Positives = 54/89 (60%), Gaps = 0/89 (0%) Query 168 KTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEV 227 K + + + KP + + Y RD V + L +++G CE C + APF DG P+LEV Sbjct 5 KEMVENQPKTKPSKRTTTSETYQRDEKVVRYALLRAQGYCELCEEPAPFSKKDGTPFLEV 64 Query 228 HHVIPLSSGGADTTDNCVALCPNCHRELH 256 HH+ LS GG D+ DN ALCPNCHR++H Sbjct 65 HHIDFLSQGGDDSKDNVSALCPNCHRKMH 93 >gb|ECI86970.1| hypothetical protein GOS_3101369 [marine metagenome] Length=114 Score = 84.7 bits (208), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 37/70 (52%), Positives = 49/70 (70%), Gaps = 1/70 (1%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 + R+P V A L ++ G+C+ C + APF DG PYLEVHH I L++GG DT +N +AL Sbjct 44 FKRNPDVVAEALIRANGVCQGCNQPAPFIRRKDGTPYLEVHHKIKLANGGDDTVENTIAL 103 Query 248 CPNCHRELHY 257 CPNCHRE H+ Sbjct 104 CPNCHREEHF 113 >gb|EBG21407.1| hypothetical protein GOS_9471027 [marine metagenome] Length=251 Score = 84.3 bits (207), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 36/66 (54%), Positives = 47/66 (71%), Gaps = 1/66 (1%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLSSGGADTTDNCVAL 247 Y RDP V+A++L S+G CE+C NAPF + N YLE+HH+ L+ GG+DT N VA+ Sbjct 186 YSRDPAVEAFVLNASQGKCESCNMNAPFIRSSNNSYYLEIHHIKRLADGGSDTVSNAVAV 245 Query 248 CPNCHR 253 CPNCHR Sbjct 246 CPNCHR 251 >ref|ZP_03942694.1| possible HNH endonuclease [Lactobacillus buchneri ATCC 11577] gb|EEI19422.1| possible HNH endonuclease [Lactobacillus buchneri ATCC 11577] Length=193 Score = 84.3 bits (207), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 42/127 (33%), Positives = 70/127 (55%), Gaps = 1/127 (0%) Query 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEV-ERLQKVYVRDPMVKAW 198 I E+ S+ ++++ M + KLI+ + +G E ++VR+ + Sbjct 49 IANKEVLHQSEIKQEQAVKKMPIKKLIESVKTHEQGKTAKTSCREVTTTMFVRNANNRHL 108 Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 L SKG+C+ CG+ APF G PYLEVHH+ S GG D +N +A+CPNCHR++H Sbjct 109 ALYFSKGVCQLCGEPAPFKDKTGQPYLEVHHIDWFSQGGKDVIENEIAICPNCHRKMHII 168 Query 259 KNAKELI 265 ++ +++ Sbjct 169 QDPNDVL 175 >ref|ZP_06675235.1| putative restriction endonuclease [Enterococcus faecium E1039] gb|EFF31492.1| putative restriction endonuclease [Enterococcus faecium E1039] Length=341 Score = 84.3 bits (207), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 34/70 (48%), Positives = 47/70 (67%), Gaps = 1/70 (1%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 K+Y R+P V ++ + +KGIC+ C + PF + DG PYL HH+ LS GG D +NC+A Sbjct 247 KIYKRNPFVSEYVKRLAKGICQLCQEKGPF-IKDGVPYLHCHHIEYLSQGGKDVIENCIA 305 Query 247 LCPNCHRELH 256 LCPNCH +H Sbjct 306 LCPNCHARIH 315 >ref|ZP_01957981.1| HNH endonuclease [Vibrio cholerae MZO-3] gb|EAY39829.1| HNH endonuclease [Vibrio cholerae MZO-3] Length=263 Score = 84.3 bits (207), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 1/86 (1%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 E++ + R +K + +++ G+CE CG +PF G PY+EVHH+ L+ GGAD + Sbjct 167 EQVTHIRYRSEDIKLYAKKRANGVCEACGSKSPFETKTG-PYIEVHHLTRLADGGADCPE 225 Query 243 NCVALCPNCHRELHYSKNAKELIEML 268 N +ALCP CHR HYS + KE E L Sbjct 226 NVIALCPTCHRRAHYSIDNKEFNEKL 251 >gb|EBK97490.1| hypothetical protein GOS_8644480 [marine metagenome] Length=70 Score = 82.8 bits (203), Expect = 6e-14, Method: Composition-based stats. Identities = 34/59 (57%), Positives = 44/59 (74%), Gaps = 1/59 (1%) Query 200 LQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 L+++ G CE C K APF + +G PYLEVHHV+PL+ GG D TDN ALCPNCH++ H+ Sbjct 4 LKRANGFCELCSKPAPFNRVKNGEPYLEVHHVVPLAQGGLDRTDNTKALCPNCHKKYHF 62 >ref|ZP_04075199.1| restriction endonuclease [Bacillus thuringiensis IBL 200] gb|EEM93088.1| restriction endonuclease [Bacillus thuringiensis IBL 200] Length=212 Score = 82.8 bits (203), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 38/74 (51%), Positives = 45/74 (60%), Gaps = 0/74 (0%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 E K YVRD V + +++ GICE C + APF GNPYLE HHV LS GG D+ Sbjct 118 EATTKTYVRDEYVAQYAKERANGICELCDQPAPFLDKKGNPYLESHHVEWLSRGGKDSIY 177 Query 243 NCVALCPNCHRELH 256 N V +C NCHR LH Sbjct 178 NTVGVCANCHRRLH 191 >ref|ZP_08244461.1| HNH endonuclease domain protein [Streptococcus parauberis NCFD 2020] gb|EGE53063.1| HNH endonuclease domain protein [Streptococcus parauberis NCFD 2020] Length=284 Score = 82.4 bits (202), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 38/103 (36%), Positives = 65/103 (63%), Gaps = 2/103 (1%) Query 155 ESLLNMRVSKLIKKTLS-QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN 213 +++ N S+L+ K LS E ++ + + +VY R+P ++ ++ + GIC+ C + Sbjct 163 KTVKNFSQSELLTKALSYSKENAQNTIFRKVSTQVYDRNPYIREYVKSLAHGICQLCQQP 222 Query 214 APFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 APF + DG P+L VHH+ L++GG DT +N +A+CPNCH +H Sbjct 223 APFEV-DGEPFLHVHHIEYLANGGHDTIENSIAICPNCHYRIH 264 >ref|ZP_05104468.1| HNH endonuclease domain protein [Methylophaga thiooxidans DMS010] gb|EEF80068.1| HNH endonuclease domain protein [Methylophaga thiooxydans DMS010] Length=274 Score = 82.0 bits (201), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 43/123 (34%), Positives = 66/123 (53%), Gaps = 8/123 (6%) Query 155 ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNA 214 +SLL +R + L K + ++ ER Q Y R ++ ++ +++ G CE C A Sbjct 157 KSLLELREAALEKPSHTKNAS-------ERRQSAYYRSKALRLYVRKRAGGKCEACAVPA 209 Query 215 PFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINR 274 PF G PY+E HH+ ++ GG D N + LCPNCHR HY+KN +E + L + Sbjct 210 PFESRKG-PYIECHHLHRVADGGPDHPMNVIGLCPNCHRRAHYAKNFREFNDSLKPVVRE 268 Query 275 LQK 277 L+K Sbjct 269 LEK 271 >gb|ECN42405.1| hypothetical protein GOS_5991417 [marine metagenome] Length=94 Score = 82.0 bits (201), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 38/87 (43%), Positives = 53/87 (60%), Gaps = 0/87 (0%) Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 R ++KA+ +SKG+CE C APF +G PYLEVHH+ LS GAD N A+CPN Sbjct 5 RKDIIKAYAHLRSKGVCEACDSRAPFISKNGKPYLEVHHIKALSENGADHPCNVAAICPN 64 Query 251 CHRELHYSKNAKELIEMLYVNINRLQK 277 CHR + + + +E+ L+ I L+K Sbjct 65 CHRRVDHGIDGEEINRSLWEKIQLLEK 91 >gb|ECT90871.1| hypothetical protein GOS_4098770 [marine metagenome] Length=194 Score = 81.6 bits (200), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 35/70 (50%), Positives = 46/70 (65%), Gaps = 0/70 (0%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 K Y R +V +++ G C+ C APF DG PYLE HH++ LS+GG DT +N VA Sbjct 123 KTYERSSIVSELAKRRAGGRCQLCLMEAPFKTKDGLPYLETHHIVWLSNGGEDTPENTVA 182 Query 247 LCPNCHRELH 256 LCPNCHR++H Sbjct 183 LCPNCHRKMH 192 >ref|ZP_04146973.1| restriction endonuclease [Bacillus thuringiensis serovar tochigiensis BGSC 4Y1] gb|EEM21365.1| restriction endonuclease [Bacillus thuringiensis serovar tochigiensis BGSC 4Y1] Length=333 Score = 81.6 bits (200), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 2/111 (1%) Query 159 NMRVSKLIKKTLSQPEGSRKPVEVERLQKV--YVRDPMVKAWILQQSKGICENCGKNAPF 216 N + KL + L + P +R K Y R+ V + +++ GICE C + APF Sbjct 210 NKKARKLDYQKLKERAKKATPSSNKRYTKTETYQRNEFVAEFSKRRANGICELCEQQAPF 269 Query 217 YLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267 +GNPYLE HHV LS GG DT N V +C NCHR LH + +++++ Sbjct 270 EDKEGNPYLESHHVEWLSEGGEDTIYNTVGVCANCHRRLHVLNDENDVMKL 320 >ref|YP_003967142.1| HNH endonuclease [Ilyobacter polytropus DSM 2926] gb|ADO82794.1| HNH endonuclease [Ilyobacter polytropus DSM 2926] Length=355 Score = 81.3 bits (199), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 42/118 (35%), Positives = 67/118 (56%), Gaps = 12/118 (10%) Query 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198 +II +++ + +D++ + N+ S+ + S++ VE Y R+ V + Sbjct 229 NIIEKRENKIRKLSDEQLIKNIANSRKV--------SSKRNVET----TTYERNQHVVEY 276 Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 +++KG CE C + APF D PYLEVHH+ LS+GG D+ N ALCPNCHR++H Sbjct 277 AKRRAKGKCELCEEEAPFLTKDKQPYLEVHHIQWLSNGGEDSITNVAALCPNCHRKMH 334 >ref|ZP_05096021.1| HNH endonuclease domain protein [marine gamma proteobacterium HTCC2148] gb|EEB77535.1| HNH endonuclease domain protein [marine gamma proteobacterium HTCC2148] Length=273 Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 33/81 (40%), Positives = 52/81 (64%), Gaps = 0/81 (0%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 K Y RDP + + +++ G C+ C +APF G PYLE HH+ L++GG D+ N VA Sbjct 185 KYYERDPWISEYAKRRAGGKCQLCESDAPFISKAGEPYLETHHIEWLANGGEDSISNTVA 244 Query 247 LCPNCHRELHYSKNAKELIEM 267 LCPNCHR++H + +++++ Sbjct 245 LCPNCHRKMHNIADNNDVVKL 265 >ref|YP_751179.1| HNH endonuclease [Shewanella frigidimarina NCIMB 400] gb|ABI72341.1| HNH endonuclease [Shewanella frigidimarina NCIMB 400] Length=309 Score = 80.1 bits (196), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 9/125 (7%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQ 202 GE++E + +DDE L ++ ++ + P + Y R VK + L+ Sbjct 184 GEINEATFISDDE---------LWERICTENPKRKSPKKTTTETVGYERSEFVKEYALRH 234 Query 203 SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262 + G C+ C PF G +LEVHH+ LS GG D +N V LCPNCHR++H +AK Sbjct 235 ANGKCQLCNNAGPFATKSGRNFLEVHHIDWLSKGGLDMPENVVGLCPNCHRKMHNINDAK 294 Query 263 ELIEM 267 ++ ++ Sbjct 295 DIKKL 299 >ref|YP_300163.1| restriction endonuclease [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305] dbj|BAE17218.1| putative restriction endonuclease [Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305] Length=328 Score = 79.7 bits (195), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 37/74 (50%), Positives = 48/74 (64%), Gaps = 0/74 (0%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 E + KVY R+ V A + +S G C+ C K APF +G YLE HHV L++GG D+ D Sbjct 232 EAVTKVYARNIHVAAHVKNRSNGYCDLCNKPAPFKDRNGRAYLECHHVDWLANGGKDSID 291 Query 243 NCVALCPNCHRELH 256 N VAL PNCHR++H Sbjct 292 NAVALDPNCHRKMH 305 >ref|ZP_04177672.1| restriction endonuclease [Bacillus cereus AH1273] ref|ZP_04180150.1| restriction endonuclease [Bacillus cereus AH1272] gb|EEL88196.1| restriction endonuclease [Bacillus cereus AH1272] gb|EEL90649.1| restriction endonuclease [Bacillus cereus AH1273] Length=331 Score = 79.3 bits (194), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 39/80 (48%), Positives = 47/80 (58%), Gaps = 2/80 (2%) Query 179 PVEVERLQKV--YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG 236 PV +R K Y R+ V + +++ GICE C + APF GNPYLE HHV LS G Sbjct 228 PVSNKRYTKTETYQRNEFVAEFSKRRANGICELCEQKAPFEDKKGNPYLESHHVEWLSEG 287 Query 237 GADTTDNCVALCPNCHRELH 256 G DT N V +C NCHR LH Sbjct 288 GEDTIYNTVGVCANCHRRLH 307 >ref|YP_003406048.1| HNH endonuclease [Haloterrigena turkmenica DSM 5511] gb|ADB63375.1| HNH endonuclease [Haloterrigena turkmenica DSM 5511] Length=84 Score = 79.0 bits (193), Expect = 7e-13, Method: Composition-based stats. Identities = 33/74 (44%), Positives = 48/74 (64%), Gaps = 0/74 (0%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 ++ + LQ + G+C+ C +APF +D +LEVHH+ S+GGAD N +ALCPNCHR Sbjct 1 MRKYALQVADGVCQGCSDDAPFLTDDRESFLEVHHLRRRSNGGADHPKNVIALCPNCHRR 60 Query 255 LHYSKNAKELIEML 268 +H+ +N E E L Sbjct 61 VHHGRNGDEFNEDL 74 >ref|ZP_05658159.1| HNH endonuclease [Enterococcus faecium 1,230,933] gb|EEV41492.1| HNH endonuclease [Enterococcus faecium 1,230,933] Length=94 Score = 79.0 bits (193), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 1/68 (1%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 Y R+P V ++ + +KGIC+ C + PF + DG PYL HH+ LS GG D +NC+ALC Sbjct 2 YKRNPFVSEYVKRLAKGICQLCQEKGPF-IKDGVPYLHCHHIEYLSQGGKDVIENCIALC 60 Query 249 PNCHRELH 256 PNCH +H Sbjct 61 PNCHARIH 68 >ref|ZP_05674502.1| LOW QUALITY PROTEIN: restriction endonuclease [Enterococcus faecium 1,231,408] gb|EEV57835.1| LOW QUALITY PROTEIN: restriction endonuclease [Enterococcus faecium 1,231,408] Length=96 Score = 78.6 bits (192), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 33/68 (48%), Positives = 45/68 (66%), Gaps = 1/68 (1%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 Y R+P V ++ + +KGIC+ C + PF + DG PYL HH+ LS GG D +NC+ALC Sbjct 4 YKRNPFVSEYVKRLAKGICQLCQEKGPF-IKDGVPYLHCHHIEYLSQGGKDVIENCIALC 62 Query 249 PNCHRELH 256 PNCH +H Sbjct 63 PNCHARIH 70 >ref|YP_761227.1| hypothetical protein HNE_2533 [Hyphomonas neptunium ATCC 15444] gb|ABI77167.1| conserved domain protein [Hyphomonas neptunium ATCC 15444] Length=343 Score = 78.6 bits (192), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 44/130 (33%), Positives = 65/130 (50%), Gaps = 5/130 (3%) Query 139 SIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAW 198 ++ E E + D S+ ++R S T + + P E R+ + R +KA+ Sbjct 206 AVADSETDEEIEDQPDTSIDDLRTSAYEAATAVR---NSNPKEARRVYRQ--RSAKIKAY 260 Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 IL ++ G+CE G+ APF G+PYLEVHH LS G D A+ P HRE+H+ Sbjct 261 ILARAGGVCELTGEKAPFLTKSGHPYLEVHHTQRLSDDGLDHPRWVAAISPTAHREIHFG 320 Query 259 KNAKELIEML 268 + EL E L Sbjct 321 ERGDELNERL 330 >ref|ZP_04682599.1| Hypothetical protein OINT_2001093 [Ochrobactrum intermedium LMG 3301] gb|EEQ93903.1| Hypothetical protein OINT_2001093 [Ochrobactrum intermedium LMG 3301] Length=282 Score = 77.8 bits (190), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 2/124 (1%) Query 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204 L + + DDE + ++ Q GSR+ R +Y R V+ ++L ++ Sbjct 148 LENIVEAVDDEQPVPAVDLAAMRDLARQAAGSREGKASTR--TIYERSRHVRDYVLARAN 205 Query 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264 G CE C APF +G PYLE HH+ +S GG D +ALCP CHR++H+ + Sbjct 206 GHCEGCSCQAPFLRINGQPYLEPHHIRRVSDGGPDDPSYVIALCPTCHRKVHHGQGGATY 265 Query 265 IEML 268 + L Sbjct 266 NDTL 269 >gb|EBP41480.1| hypothetical protein GOS_7915120 [marine metagenome] Length=167 Score = 77.4 bits (189), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 34/87 (39%), Positives = 51/87 (58%), Gaps = 0/87 (0%) Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 R+ VK + +++ G CE C APF+ +G PYLEVHH+ L+ G DT N A+CPN Sbjct 77 RNRWVKIYAKERANGNCEGCSNEAPFFTKNGTPYLEVHHIQSLADNGPDTPINVAAICPN 136 Query 251 CHRELHYSKNAKELIEMLYVNINRLQK 277 CH+ S+++++ L I L+K Sbjct 137 CHQRAELSEDSEQFNLQLKNKIENLEK 163 >ref|YP_003563225.1| hypothetical protein BMQ_2769 [Bacillus megaterium QM B1551] gb|ADE69791.1| conserved hypothetical protein [Bacillus megaterium QM B1551] Length=269 Score = 74.3 bits (181), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 32/91 (35%), Positives = 54/91 (59%), Gaps = 0/91 (0%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 E+ VY + +K ++ +++ GICE CG++APF DG+ +L+++++ LS G Sbjct 170 EKKTSVYEQTAALKQYVHKRAAGICEACGESAPFIAKDGSSFLQMYYLSKLSESGLAKPK 229 Query 243 NCVALCPNCHRELHYSKNAKELIEMLYVNIN 273 + ALCPNC+ L Y K+++ E L IN Sbjct 230 DAAALCPNCYSRLRYGKDSEVYKEELITKIN 260 >ref|YP_003597996.1| hypothetical protein BMD_2805 [Bacillus megaterium DSM 319] gb|ADF39646.1| conserved hypothetical protein [Bacillus megaterium DSM 319] Length=269 Score = 73.9 bits (180), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 32/91 (35%), Positives = 53/91 (58%), Gaps = 0/91 (0%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 E+ VY + K ++ +++ GICE CG++APF DG+ +L+++++ LS G Sbjct 170 EKKTSVYEQTAAFKQYVHKRAAGICEACGESAPFIAKDGSSFLQMYYLSKLSESGLAKPK 229 Query 243 NCVALCPNCHRELHYSKNAKELIEMLYVNIN 273 + ALCPNC+ L Y K+++ E L IN Sbjct 230 DAAALCPNCYSRLRYGKDSEVYKEELITKIN 260 >ref|YP_004069992.1| restriction endonuclease-like protein [Pseudoalteromonas sp. SM9913] gb|ADT69841.1| restriction endonuclease-like protein [Pseudoalteromonas sp. SM9913] Length=277 Score = 72.4 bits (176), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 33/81 (40%), Positives = 49/81 (60%), Gaps = 1/81 (1%) Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 E E+ Y R +++ +L +S G CE C + F N G+ YLE HH++PLS GG D+ Sbjct 178 EYEKYGVEYARSSVIRRKVLLRSNGKCEYCLSDG-FITNSGDKYLETHHILPLSQGGDDS 236 Query 241 TDNCVALCPNCHRELHYSKNA 261 N +ALCP HR+ H+ K++ Sbjct 237 FINVIALCPKDHRKAHFEKDS 257 >ref|ZP_02150571.1| putative restriction endonuclease [Phaeobacter gallaeciensis 2.10] gb|EDQ07993.1| putative restriction endonuclease [Phaeobacter gallaeciensis 2.10] Length=220 Score = 71.6 bits (174), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 32/70 (45%), Positives = 43/70 (61%), Gaps = 1/70 (1%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 V+VR+ + Q + G+C+ C K F G+ +LEVHH LS GG DT +N VAL Sbjct 146 VFVRNSEFSRRVRQAANGVCDAC-KGKTFQTQSGDWFLEVHHKKWLSEGGTDTIENMVAL 204 Query 248 CPNCHRELHY 257 CPNCHR+ H+ Sbjct 205 CPNCHRQEHF 214 >ref|ZP_06918687.1| conserved hypothetical protein [Streptomyces sviceus ATCC 29083] gb|EDY56883.2| conserved hypothetical protein [Streptomyces sviceus ATCC 29083] Length=481 Score = 70.5 bits (171), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 8/134 (5%) Query 148 LSQPTDDESLLNM--RVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKG 205 L PT +ES + R+++ + + G +KP L YVRDP +A ++++ +G Sbjct 348 LEAPTTEESDEDAYRRLAQKAEANAERRRGLKKPT----LADKYVRDPSARAAVIKRCRG 403 Query 206 ICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263 CEN C + G P L+V HV L+ G D N +ALCPNCH Y +N + Sbjct 404 RCENPQCAGHPTELTTAGLPILQVDHVKDLAKKGPDVPWNMIALCPNCHALKTYGENREN 463 Query 264 LIEMLYVNINRLQK 277 L +L RL + Sbjct 464 LRRLLTATARRLHE 477 >ref|YP_003620463.1| putative restriction endonuclease [Leuconostoc kimchii IMSNU 11154] gb|ADG39494.1| putative restriction endonuclease [Leuconostoc kimchii IMSNU 11154] Length=288 Score = 69.7 bits (169), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 0/75 (0%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 + R P + ++ + G C C + APF P+L HH+ LS GG DT +NC+A+C Sbjct 203 FERSPYIANYVKHIANGYCSLCEQLAPFLDKYNQPFLHAHHINYLSDGGEDTIENCIAVC 262 Query 249 PNCHRELHYSKNAKE 263 PNCH ++H + K+ Sbjct 263 PNCHAKIHALNDPKD 277 >ref|ZP_08481963.1| putative restriction endonuclease [Leuconostoc inhae KCTC 3774] Length=288 Score = 69.7 bits (169), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 0/75 (0%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 + R P + ++ + G C C + APF P+L HH+ LS GG DT +NC+A+C Sbjct 203 FERSPYIANYVKHIANGYCSLCEQLAPFLDKYNQPFLHAHHINYLSDGGEDTIENCIAVC 262 Query 249 PNCHRELHYSKNAKE 263 PNCH ++H + K+ Sbjct 263 PNCHAKIHALNDPKD 277 >ref|YP_001817971.1| HNH endonuclease [Opitutus terrae PB90-1] gb|ACB74371.1| HNH endonuclease [Opitutus terrae PB90-1] Length=279 Score = 69.3 bits (168), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 5/74 (6%) Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 R+P V+ W+L++S+G+CE G + +L+VHH++ + G D NCVALCPN Sbjct 194 RNPKVRRWVLKRSRGVCERLGCHITRSFAG---FLDVHHILGAAKG--DRVWNCVALCPN 248 Query 251 CHRELHYSKNAKEL 264 CHRE H + N K++ Sbjct 249 CHRETHCAPNRKKI 262 >gb|ECH87844.1| hypothetical protein GOS_3518611 [marine metagenome] Length=62 Score = 65.5 bits (158), Expect = 1e-08, Method: Composition-based stats. Identities = 26/43 (60%), Positives = 33/43 (76%), Gaps = 0/43 (0%) Query 214 APFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 APF DG+ YLE HH++ LS+ G DT +N VALCPNCHR++H Sbjct 3 APFKTKDGSAYLETHHIVWLSNEGEDTPENTVALCPNCHRKMH 45 >ref|ZP_02076561.1| hypothetical protein EUBDOL_00350 [Eubacterium dolichum DSM 3991] gb|EDP12104.1| hypothetical protein EUBDOL_00350 [Eubacterium dolichum DSM 3991] Length=508 Score = 65.1 bits (157), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 37/96 (38%), Positives = 52/96 (54%), Gaps = 6/96 (6%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSG-----GADTT 241 +Y R+ + SK CE K+ F NDG PY+E HH+IP+S D Sbjct 396 IYKRERKRANNAIIHSKHQCEIDAKHISFKRKNDGFPYMEAHHLIPMSKQDLFEYSLDVE 455 Query 242 DNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 +N V+LC CHRE+H+ +NA LI+ LY + +L K Sbjct 456 ENIVSLCSQCHREIHHGENADALIKKLYNDRKKLLK 491 >ref|YP_003518255.1| HNH endonuclease typeIV restriction enzyme [Cupriavidus metallidurans CH34] gb|ABF13188.1| HNH endonuclease typeIV restriction enzyme [Cupriavidus metallidurans CH34] Length=348 Score = 65.1 bits (157), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 17/100 (17%) Query 175 GSRKPVEVERLQKVYV-RDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVI 231 GS P E ++ YV RD V+ +L ++ G+CEN C APF +L+VHH+ Sbjct 248 GSDSP-ERRTAERSYVKRDDRVRRQVLDRADGVCENPTCSIRAPF-----PSFLDVHHIF 301 Query 232 PLSSGGADTTD---NCVALCPNCHRELHYSKNAKELIEML 268 G +T+D NCVA+CPNCHR HY+ + + E L Sbjct 302 -----GVETSDRAWNCVAICPNCHRAAHYAPDRSAINEEL 336 >ref|YP_350356.1| HNH endonuclease [Pseudomonas fluorescens Pf0-1] gb|ABA76365.1| Putative HNH endonuclease [Pseudomonas fluorescens Pf0-1] Length=323 Score = 64.7 bits (156), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 37/111 (33%), Positives = 60/111 (54%), Gaps = 13/111 (11%) Query 162 VSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE--NCGKNAPFYLN 219 V+ L L + E SR V R+ RDP V+ ++ + G CE CG + + Sbjct 212 VAGLDLSLLGRDEASRYQATVSRV----ARDPSVRKAVIDRCNGRCERPGCGASRSY--- 264 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYV 270 + +L+VHH++ + +D NCVALCPNCHR+ H+S + ++L + L + Sbjct 265 --SGFLDVHHILGVEI--SDRVANCVALCPNCHRDAHFSADRQKLNDSLLI 311 >ref|NP_628792.1| hypothetical protein SCO4631 [Streptomyces coelicolor A3(2)] emb|CAB77405.1| hypothetical protein SCD82.01c [Streptomyces coelicolor A3(2)] Length=560 Score = 64.3 bits (155), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/91 (37%), Positives = 45/91 (49%), Gaps = 2/91 (2%) Query 189 YVRDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 YVRDP + +L++ + CEN C + G P L+V HV L+ GG D N +A Sbjct 466 YVRDPSARGAVLKRCQKRCENPECAGHPTELTKAGLPILQVDHVNDLAKGGPDVPWNMIA 525 Query 247 LCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 LCPNCH Y N L +L RL + Sbjct 526 LCPNCHALKTYGANKVRLQRLLAATARRLHE 556 >gb|EEE73045.1| predicted protein [Populus trichocarpa] Length=222 Score = 63.5 bits (153), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 39/100 (39%), Positives = 55/100 (55%), Gaps = 17/100 (17%) Query 175 GSRKPVEVERLQKVYV-RDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVI 231 GS P E ++ YV RD V+ +L ++ G+CEN C APF +L+VHH+ Sbjct 122 GSDSP-ERRTAERSYVKRDDRVRRQVLDRADGVCENPTCSIRAPF-----PSFLDVHHIF 175 Query 232 PLSSGGADTTD---NCVALCPNCHRELHYSKNAKELIEML 268 G +T+D NCVA+CPNCHR HY+ + + E L Sbjct 176 -----GVETSDRAWNCVAICPNCHRAAHYAPDRSAINEEL 210 >ref|ZP_02428247.1| hypothetical protein CLORAM_01640 [Clostridium ramosum DSM 1402] gb|EDS18691.1| hypothetical protein CLORAM_01640 [Clostridium ramosum DSM 1402] Length=329 Score = 63.5 bits (153), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 39/99 (39%), Positives = 51/99 (51%), Gaps = 7/99 (7%) Query 178 KPVEVE-RLQKVYVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNPYLEVHHVIPLS- 234 KP VE + KVY R+ V L + CE + DG PY E HH+IP++ Sbjct 206 KPKLVENKFNKVYKRNKAVAINALGIANFSCEIDKKHKTFKRKKDGVPYTEPHHLIPMAF 265 Query 235 ----SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269 D +N V+LC NCH E+HY +NA+ELI LY Sbjct 266 QDEFDFSIDIEENIVSLCSNCHNEIHYGENARELITKLY 304 >ref|ZP_04114617.1| 5-methylcytosine-specific restriction enzyme A [Bacillus thuringiensis serovar kurstaki str. T03a001] ref|ZP_04211902.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus Rock4-2] gb|EEL56394.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus Rock4-2] gb|EEM53693.1| 5-methylcytosine-specific restriction enzyme A [Bacillus thuringiensis serovar kurstaki str. T03a001] Length=166 Score = 60.8 bits (146), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 10/134 (7%) Query 145 LSELSQPTDD-ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 LSE Q D ++ ++ SK+ +PE +RK ++E ++V+ RDP ++Q+ Sbjct 7 LSEDEQEEDMYQANIDSDFSKVKIAEEEKPE-NRKKTKMESGREVWPRDPKKAKQAIKQA 65 Query 204 KGICENCGKNAPFYLNDGNP-YLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHY 257 + CE + F Y+E HH+IPL D N V++CPNCHR +HY Sbjct 66 EFKCEIDDTHETFVSEASRKNYMEAHHLIPLRMQHDFENSLDVVGNIVSICPNCHRLIHY 125 Query 258 --SKNAKELIEMLY 269 K+ K+++E+L+ Sbjct 126 GRDKDKKKVLELLF 139 >ref|ZP_04203007.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus F65185] gb|EEL65350.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus F65185] Length=166 Score = 60.8 bits (146), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/134 (31%), Positives = 70/134 (52%), Gaps = 10/134 (7%) Query 145 LSELSQPTDD-ESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 LSE Q D ++ ++ SK+ +PE +RK ++E ++V+ RDP ++Q+ Sbjct 7 LSEDEQEEDMYQANIDSDFSKVKIAEEEKPE-NRKKTKMESGREVWPRDPKKAKQAIKQA 65 Query 204 KGICENCGKNAPFYLNDGNP-YLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHY 257 + CE + F Y+E HH+IPL D N V++CPNCHR +HY Sbjct 66 EFKCEIDDTHETFVSEASRKNYMEAHHLIPLRMQHDFEDSLDVVGNIVSICPNCHRLIHY 125 Query 258 --SKNAKELIEMLY 269 K+ K+++E+L+ Sbjct 126 GRDKDKKKVLELLF 139 >ref|YP_724534.1| restriction endonuclease [Ralstonia eutropha H16] emb|CAJ91166.1| predicted restriction endonuclease [Ralstonia eutropha H16] Length=371 Score = 60.5 bits (145), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 9/98 (9%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGG-----ADTTD 242 Y RDP+V A ++ ++ CE ++ F + N PY+E HH+IPLS D T Sbjct 251 YPRDPLVAAEAVKSAEYRCELFPEHQTFKSSSKNVPYVEAHHLIPLSRQADFQFSLDITA 310 Query 243 NCVALCPNCHRELHY---SKNAKELIEMLYVNINRLQK 277 N +ALCP CH+ LH+ S+ L +L +RLQ+ Sbjct 311 NIIALCPTCHQRLHHGHASERRSPLRRLLSQRKDRLQE 348 >ref|ZP_00990414.1| putative restriction endonuclease [Vibrio splendidus 12B01] gb|EAP94706.1| putative restriction endonuclease [Vibrio splendidus 12B01] Length=259 Score = 60.1 bits (144), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 5/111 (4%) Query 153 DDESLLNMRVSKLIKKTLSQ-----PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGIC 207 D +S+ ++RV K K T+ + +G + ++ Y R+ V + +KG C Sbjct 146 DRDSVESVRVRKAKKLTVEELQALAAKGRKTATRYQQKSTSYERNIWVAELAKRLAKGQC 205 Query 208 ENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 + C K APF G PYLE HH+ LS GG DT +N + P +E +S Sbjct 206 QLCLKPAPFKNTKGEPYLETHHIAWLSKGGEDTAENTSRIVPQLPQENAHS 256 >ref|ZP_04248670.1| hypothetical protein bcere0017_56020 [Bacillus cereus Rock1-3] gb|EEL19671.1| hypothetical protein bcere0017_56020 [Bacillus cereus Rock1-3] Length=72 Score = 60.1 bits (144), Expect = 4e-07, Method: Composition-based stats. Identities = 26/47 (55%), Positives = 31/47 (65%), Gaps = 0/47 (0%) Query 210 CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 C ++APF GNPYLE HHV L+ G DT N V +C NCHR+LH Sbjct 2 CEQHAPFQDKKGNPYLEAHHVKWLAEDGEDTIYNTVGVCANCHRKLH 48 >ref|ZP_04242774.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus Rock1-15] ref|ZP_04256581.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus BDRD-Cer4] ref|ZP_04273188.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus BDRD-ST24] gb|EEK95109.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus BDRD-ST24] gb|EEL11783.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus BDRD-Cer4] gb|EEL25523.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus Rock1-15] Length=130 Score = 59.7 bits (143), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 37/117 (31%), Positives = 61/117 (52%), Gaps = 10/117 (8%) Query 163 SKLIKKTLSQPEGS--RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND 220 S K +++ E S RK ++E ++V+ RDP ++Q++ CE + F Sbjct 13 SDFSKVKIAEEEKSENRKKTKMESGREVWPRDPKKAKQAIKQAEFKCEIDDTHETFVSEA 72 Query 221 GNP-YLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHY--SKNAKELIEMLY 269 Y+E HH+IPL D N V++CPNCHR +HY K+ K+++E+L+ Sbjct 73 SRKNYMEAHHLIPLRMQHDFENSLDVVGNIVSICPNCHRLIHYGRDKDKKKVLELLF 129 >gb|EDC34285.1| hypothetical protein GOS_1492930 [marine metagenome] Length=446 Score = 59.3 bits (142), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 7/88 (7%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG-----GADTTDN 243 Y R+P A+ L+++ +CE + F + Y+E HHVIP+ + D +N Sbjct 334 YQRNPSYSAYALKKANYLCELDNSHQTFKRENSRNYVEGHHVIPMHAQEDFEYSIDVPEN 393 Query 244 CVALCPNCHRELHYS--KNAKELIEMLY 269 VALCPNCHR++H + + K+++ L+ Sbjct 394 IVALCPNCHRKVHSANEETKKDIVNKLF 421 >ref|ZP_07388900.1| conserved hypothetical protein [Paenibacillus curdlanolyticus YK9] gb|EFM09529.1| conserved hypothetical protein [Paenibacillus curdlanolyticus YK9] Length=298 Score = 58.9 bits (141), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 7/91 (7%) Query 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG- 237 P E L+ Y R V L++++ CE + F G P++E HH+IP+S G Sbjct 174 PTETTVLR--YPRKASVALEALEKARYCCEVDPTHKTFIGVSGKPFMECHHLIPISLQGR 231 Query 238 ----ADTTDNCVALCPNCHRELHYSKNAKEL 264 D +N V+LCP CHR LHYS +L Sbjct 232 FSVSLDICENIVSLCPTCHRLLHYSSEPSKL 262 >ref|ZP_06249276.1| transcriptional regulator, XRE family [Clostridium thermocellum JW20] gb|EFB39916.1| transcriptional regulator, XRE family [Clostridium thermocellum JW20] Length=446 Score = 58.5 bits (140), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/89 (33%), Positives = 49/89 (55%), Gaps = 8/89 (8%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLSSGGA-----DTTD 242 ++R+P V L++++ CE + F N PY+E HH+IP+S+ D T Sbjct 332 FLRNPKVAIQALKKAQYKCEINDAHETFIAKSSNKPYVESHHLIPISNSAMFGFSIDITA 391 Query 243 NCVALCPNCHRELHYSKN--AKELIEMLY 269 N +LCPNCHR +H + + +E++ LY Sbjct 392 NICSLCPNCHRAIHSATDEVKREMLTKLY 420 >ref|ZP_06912007.1| predicted protein [Streptomyces pristinaespiralis ATCC 25486] gb|EFH31682.1| predicted protein [Streptomyces pristinaespiralis ATCC 25486] Length=239 Score = 58.5 bits (140), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 27/65 (41%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Query 190 VRDPMVKAWILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 VR + + +L +S+G CEN CG + G P LEV H++ L+ GG D AL Sbjct 142 VRSAVARRAVLARSRGACENPACGGRPADVTDAGEPILEVDHIMDLAKGGPDHPSRMAAL 201 Query 248 CPNCH 252 CPNCH Sbjct 202 CPNCH 206 >ref|YP_003313094.1| HNH endonuclease [Sanguibacter keddieii DSM 10542] gb|ACZ20260.1| HNH endonuclease [Sanguibacter keddieii DSM 10542] Length=395 Score = 58.2 bits (139), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 43/118 (36%), Positives = 61/118 (51%), Gaps = 11/118 (9%) Query 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN--CGKNAPFYLN-D 220 +L+++ L+ E + +P V R+ Y R + +L +S G CE+ C P LN Sbjct 271 ELVRR-LADLERTTEPQTVSRI--AYQRQYAARRAVLIRSAGQCESERC-TGMPAELNRK 326 Query 221 GNPYLEVHHVIPLSSGGADTTDNCVALCPNCH----RELHYSKNAKELIEMLYVNINR 274 G P L+V H++ LS GGAD N VALCPNCH R H + KEL + +R Sbjct 327 GMPILDVDHIVELSQGGADHPLNMVALCPNCHAAKTRGQHAKRWEKELRRIAQAAHDR 384 >ref|ZP_01001666.1| e14 prophage-like protein [Oceanicola batsensis HTCC2597] gb|EAQ01007.1| e14 prophage-like protein [Oceanicola batsensis HTCC2597] Length=201 Score = 58.2 bits (139), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 37/107 (34%), Positives = 53/107 (49%), Gaps = 18/107 (16%) Query 161 RVSKLIKKTLSQPEGSRKPVEVERLQKVY---------VRDPMVKAWILQQSKGICENCG 211 R + I L Q + S + EV++ QKV VRD L++ C+ G Sbjct 58 RTEEAIAADLFQDDSSSE--EVKKTQKVIETFERNRKAVRD-------LKRLYKTCQVTG 108 Query 212 KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 + F +G PYLEVHH++PL GG+D N V + + HR LHY+ Sbjct 109 DDFVFSKVNGEPYLEVHHLVPLGEGGSDDPANLVVISAHIHRMLHYA 155 >ref|ZP_01619437.1| hypothetical protein L8106_06379 [Lyngbya sp. PCC 8106] gb|EAW38405.1| hypothetical protein L8106_06379 [Lyngbya sp. PCC 8106] Length=245 Score = 57.8 bits (138), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 26/57 (45%), Positives = 34/57 (59%), Gaps = 4/57 (7%) Query 204 KGICE--NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 KG C+ +CG F +G+ Y E HH++PLS GG+ N V LCPN HR HY+ Sbjct 166 KGCCQIKDCG--FTFIQKNGDNYAEAHHLVPLSEGGSQDASNVVILCPNHHRMFHYA 220 >ref|YP_004152990.1| hnh endonuclease [Variovorax paradoxus EPS] gb|ADU34879.1| HNH endonuclease [Variovorax paradoxus EPS] Length=384 Score = 57.4 bits (137), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 35/98 (35%), Positives = 48/98 (48%), Gaps = 9/98 (9%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVHHVIPLSSG-----GADTTD 242 Y R+P V L + CE + F + G PYLE HH+IP S+ D Sbjct 264 YQRNPRVAGNALANADYKCEIDSSHQTFTAHAGEKPYLEAHHLIPFSNQRFFNVSLDVMA 323 Query 243 NCVALCPNCHRELHY---SKNAKELIEMLYVNINRLQK 277 N VALCPNCHR LH+ + +K + +L RL++ Sbjct 324 NVVALCPNCHRLLHHGTTKEKSKHIRALLAKRAERLEE 361 >gb|EBN30596.1| hypothetical protein GOS_8268251 [marine metagenome] Length=173 Score = 57.0 bits (136), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 26/60 (43%), Positives = 35/60 (58%), Gaps = 0/60 (0%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 K Y R +V +++ G C+ C APF DG PYLE HH++ LS+ G DT +N VA Sbjct 114 KTYERSSIVSELAKRRAGGRCQLCLMEAPFKTKDGLPYLETHHIVWLSNEGEDTPENTVA 173 >ref|ZP_06407844.1| 5-methylcytosine-specific restriction enzyme A (EcoKMcrA) [Prevotella melaninogenica D18] gb|EFC73369.1| 5-methylcytosine-specific restriction enzyme A (EcoKMcrA) [Prevotella melaninogenica D18] Length=138 Score = 56.2 bits (134), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 13/96 (13%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA-------- 238 K+ ++P + L +K C K+ F G PY+E HH+IP + A Sbjct 18 KMVKKNPKIAKQALAHAKYRCVANPKHITFNTAKGKPYMEGHHLIPCTQSNATLFWQTRN 77 Query 239 ---DTTDNCVALCPNCHRELHYS--KNAKELIEMLY 269 D +N V LCP CHR +HY + K LI+ LY Sbjct 78 RNIDCENNIVCLCPTCHRRIHYGSIQEKKSLIKTLY 113 >ref|ZP_05346026.1| product McrA [Bryantella formatexigens DSM 14469] gb|EET61164.1| product McrA [Bryantella formatexigens DSM 14469] Length=380 Score = 55.8 bits (133), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 28/61 (45%), Positives = 34/61 (55%), Gaps = 7/61 (11%) Query 216 FYLNDGNPYLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYS--KNAKELIEML 268 F DG PYLEVHH+IPL A DT N + LCP CHR LH+ + E++ L Sbjct 297 FLKPDGTPYLEVHHLIPLKQQPAFEYKLDTMANLIPLCPLCHRRLHHGCRADVDEMLTQL 356 Query 269 Y 269 Y Sbjct 357 Y 357 >ref|ZP_05233454.1| conserved hypothetical protein [Listeria monocytogenes FSL N3-165] gb|AAY22440.1| putative recombinase [Listeria monocytogenes] gb|EEW14499.1| conserved hypothetical protein [Listeria monocytogenes FSL N3-165] Length=284 Score = 55.5 bits (132), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 30/78 (38%), Positives = 43/78 (55%), Gaps = 7/78 (8%) Query 206 ICENCGKNAPFY-LNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSK 259 ICE ++ F + DG PY+E HH+IP++ D DN + LCP CHR++HY+ Sbjct 187 ICEFNQEHKTFINIKDGKPYVEGHHLIPMAVQDYYDNTIDFADNIICLCPTCHRKIHYAV 246 Query 260 NAKELIEMLYVNINRLQK 277 + E EML N +K Sbjct 247 QS-EKKEMLIKIFNEREK 263 >ref|YP_002773045.1| hypothetical protein BBR47_35640 [Brevibacillus brevis NBRC 100599] dbj|BAH44541.1| hypothetical protein [Brevibacillus brevis NBRC 100599] Length=360 Score = 55.5 bits (132), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 29/61 (47%), Positives = 40/61 (65%), Gaps = 8/61 (13%) Query 224 YLEVHHVIP-----LSSGGADTTDNCVALCPNCHRELHYSKNA--KELIEMLYV-NINRL 275 ++E HH+IP L S D N V+LCPNCHR++H++ + KELIE+LY INRL Sbjct 283 FVEAHHLIPMKLQALFSWSLDVPGNIVSLCPNCHRKIHHASKSERKELIEVLYSKKINRL 342 Query 276 Q 276 + Sbjct 343 K 343 >ref|ZP_01040994.1| 5-methylcytosine-specific restriction enzyme A [Erythrobacter sp. NAP1] gb|EAQ28643.1| 5-methylcytosine-specific restriction enzyme A [Erythrobacter sp. NAP1] Length=288 Score = 55.1 bits (131), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 45/172 (26%), Positives = 70/172 (40%), Gaps = 39/172 (22%) Query 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEG----------------SRKP 179 FW RG+ L Q TD + + ++ K L+ +G + P Sbjct 114 FWGVFERGDDIWLFQATD------VFMDRIRKHGLASEDGGSILEPEVDDYQSEINQKAP 167 Query 180 VEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIPLSSGG- 237 ++ QK + RDP V A L+ + CE + F + G P++E HH+IP+ + Sbjct 168 SQITSTQKAWSRDPKVAAEALKNASFECELYPELPTFTSRSTGYPFMEAHHLIPMKAQAD 227 Query 238 ----ADTTDNCVALCPNCHRELHYSKN-----------AKELIEMLYVNINR 274 D DN L P HR+LH ++ AK + YVNI + Sbjct 228 FDVSLDVVDNICCLSPFAHRKLHMAEFDDIIDDLERLIAKRAALLDYVNITK 279 >ref|NP_831911.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus ATCC 14579] ref|ZP_04120172.1| 5-methylcytosine-specific restriction enzyme A [Bacillus thuringiensis serovar pakistani str. T13001] gb|AAP09112.1| 5-methylcytosine-specific restriction enzyme A [Bacillus cereus ATCC 14579] gb|EEM48126.1| 5-methylcytosine-specific restriction enzyme A [Bacillus thuringiensis serovar pakistani str. T13001] Length=97 Score = 55.1 bits (131), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 8/96 (8%) Query 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLS-----S 235 +E ++V+ RDP ++Q++ CE + F Y+E HH+IPL Sbjct 1 MESGREVWPRDPKKAKQAIKQAEFKCEIDDTHETFVSEASRKNYMEAHHLIPLRMQHDFE 60 Query 236 GGADTTDNCVALCPNCHRELHY--SKNAKELIEMLY 269 D N V++CPNCHR +HY K+ K+++E+L+ Sbjct 61 NSLDVVGNIVSICPNCHRLIHYGRDKDKKKVLELLF 96 >ref|YP_012937.1| hypothetical protein LMOf2365_0328 [Listeria monocytogenes serotype 4b str. F2365] gb|AAT03114.1| conserved domain protein [Listeria monocytogenes serotype 4b str. F2365] Length=284 Score = 54.7 bits (130), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 7/78 (8%) Query 206 ICENCGKNAPFY-LNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSK 259 +CE ++ F + DG PY+E HH+IP++ D DN + LCP CHR++HY+ Sbjct 187 VCEFNQEHKTFINIKDGKPYVEGHHLIPMAVQDYYDNTIDFADNIICLCPTCHRKIHYAV 246 Query 260 NAKELIEMLYVNINRLQK 277 + E EML N +K Sbjct 247 QS-EKKEMLIKIFNEREK 263 >ref|ZP_08605680.1| hypothetical protein HMPREF0994_01686 [Lachnospiraceae bacterium 3_1_57FAA_CT1] gb|EGN41724.1| hypothetical protein HMPREF0994_01686 [Lachnospiraceae bacterium 3_1_57FAA_CT1] Length=300 Score = 54.7 bits (130), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 7/104 (6%) Query 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHV 230 +P+ KPV +++++ +Y RD + L ++ CE + F + N Y E HH+ Sbjct 174 KPKDKGKPVVIDKIE-IYKRDRKISLNALAYARFECEIDRTHESFIRKNSNTNYTEPHHL 232 Query 231 IPLS-----SGGADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269 +P++ S D +N V+LC NCH LHY ++ L++ LY Sbjct 233 VPMAFQNNFSVSLDVEENIVSLCSNCHNLLHYGRDYLFLLKRLY 276 >ref|YP_002886182.1| HNH endonuclease [Exiguobacterium sp. AT1b] gb|ACQ70737.1| HNH endonuclease [Exiguobacterium sp. AT1b] Length=272 Score = 54.7 bits (130), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 34/104 (32%), Positives = 49/104 (47%), Gaps = 4/104 (3%) Query 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPY 224 ++K+ L + GS + R Q++ R V IL ++ CE CG +PF DG Y Sbjct 158 IVKQNLQKVSGSSTAI---RKQQIRERSAAVYYSILARANNHCEACGSPSPFETEDG-AY 213 Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268 LE+H + S A+CPNCH LH K+ + E L Sbjct 214 LELHSLYSHSDQIILLPGLGAAVCPNCHMRLHKGKDRSQYNEQL 257 >gb|EFR95085.1| putative recombinase [Listeria innocua FSL J1-023] Length=261 Score = 54.7 bits (130), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 7/69 (10%) Query 206 ICENCGKNAPFY-LNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHRELHYSK 259 ICE ++ F + DG PY+E HH+IP++ D DN + LCP CHR++HY+ Sbjct 187 ICEFNQEHKTFINIKDGKPYVEGHHLIPMAVQDYYDNTIDFADNIICLCPTCHRKIHYAV 246 Query 260 NAKELIEML 268 + E EML Sbjct 247 QS-EKKEML 254 >ref|ZP_07839158.1| HNH endonuclease [Eubacterium cellulosolvens 6] gb|EFR64748.1| HNH endonuclease [Eubacterium cellulosolvens 6] Length=231 Score = 54.3 bits (129), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 32/95 (33%), Positives = 46/95 (48%), Gaps = 9/95 (9%) Query 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHV 230 + EG +K V R Y R P ++ ++ C CG + FY G Y+EVHHV Sbjct 126 EKEGGKKVYYVTR----YERKPKLRKKAIEIHGTKCMACGFDFESFYGEQGKNYIEVHHV 181 Query 231 IPLSSGGADTTDN----CVALCPNCHRELHYSKNA 261 +PLS+ N + +C NCHR +H +NA Sbjct 182 VPLSTVDEQVEVNPEKDMIVVCSNCHRMIHRRRNA 216 >ref|YP_004332990.1| HNH endonuclease [Pseudonocardia dioxanivorans CB1190] gb|AEA25137.1| HNH endonuclease [Pseudonocardia dioxanivorans CB1190] Length=442 Score = 53.9 bits (128), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 11/83 (13%) Query 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234 G+ +P++V R ++V + D + +A I + +G C CG+ + E+HHV+P Sbjct 318 GAGQPLDVGRARRV-IPDGLRRA-IAARDRG-CARCGRP--------PSWCEIHHVVPWE 366 Query 235 SGGADTTDNCVALCPNCHRELHY 257 SGG + DNC LC CHR +H+ Sbjct 367 SGGPTSIDNCAMLCRACHRLVHH 389 >ref|ZP_06824551.1| HNH endonuclease [Streptomyces sp. SPB74] gb|EDY42956.2| HNH endonuclease [Streptomyces sp. SPB74] Length=335 Score = 53.9 bits (128), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 30/82 (36%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query 197 AWILQQSKGI-CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNCH 252 A +L+Q + CE CG + FY G+ Y+E HHV+PL G TT + +C NCH Sbjct 234 ASVLKQGGALSCEACGFDFGKFYGERGDGYIECHHVVPLHEAGEGTTRLADLALICSNCH 293 Query 253 RELHYSKNAKELIEMLYVNINR 274 R +H S E+ V ++R Sbjct 294 RMIHRSAPWPTPAELRLVVLDR 315 >ref|NP_635336.1| 5-methylcytosine-specific restriction enzyme A [Methanosarcina mazei Go1] gb|AAM33008.1| 5-methylcytosine-specific restriction enzyme A [Methanosarcina mazei Go1] Length=257 Score = 53.5 bits (127), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 32/101 (31%), Positives = 49/101 (48%), Gaps = 9/101 (8%) Query 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADT 240 + R Y R+P+ + ++ +C+ CG + Y G Y+EVHH+ PL GG Sbjct 157 IMRYTTQYERNPINRRNAIRIHGTVCQGCGFDFEKVYGEIGKDYIEVHHIKPLYEGGGSV 216 Query 241 TDNC----VALCPNCHRELHYSKNA----KELIEMLYVNIN 273 N + +C NCHR +H K+ KEL ++L N N Sbjct 217 PINAETDLICVCANCHRMIHRRKDKVLSLKELQKLLLANKN 257 >ref|ZP_04957665.1| HNH endonuclease domain protein [gamma proteobacterium NOR51-B] gb|EED35249.1| HNH endonuclease domain protein [gamma proteobacterium NOR51-B] Length=289 Score = 53.1 bits (126), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 35/117 (29%), Positives = 51/117 (43%), Gaps = 16/117 (13%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNPYL 225 +K ++ PE + P E ++ Y R V L+ + CE + P G P + Sbjct 158 QKLVAAPEDAVVPKEYRAMR--YERSAAVGREALESAGYACEFDNTHETPLSAVTGQPIM 215 Query 226 EVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 EVHH++P+S D N V+LCPNCH +H S V + LQK Sbjct 216 EVHHLVPISKSAEFRCSLDVLANVVSLCPNCHSAIHRSTKT--------VQVAMLQK 264 >ref|YP_001420334.1| hypothetical protein RBAM_007180 [Bacillus amyloliquefaciens FZB42] gb|ABS73103.1| hypothetical protein RBAM_007180 [Bacillus amyloliquefaciens FZB42] Length=388 Score = 52.0 bits (123), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 8/107 (7%) Query 162 VSKLIKKT--LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +S+ +KKT ++Q + +P+ + QK + R+ + + + S CE + F Sbjct 241 ISESVKKTYEVNQKKVRPEPIYNKGGQKQWTRNASLASMAMMLSNYTCEIEDSHKTFISK 300 Query 220 DGN-PYLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKN 260 N P++E HH++P+S G D +N V+LCP CHR +H ++ Sbjct 301 STNKPFVECHHLVPISKQGEFQYDLDQLENMVSLCPLCHRLIHLGRD 347 >gb|EDG66067.1| hypothetical protein GOS_743329 [marine metagenome] Length=163 Score = 52.0 bits (123), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 14/91 (15%) Query 184 RLQKV---YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 RLQ + Y RD V+ + +++ G CE + + D +L+VHH++ G D Sbjct 73 RLQVIRSGYPRDARVREAVARRAGGRCE---RASCTEARDYPGFLDVHHIL-----GIDV 124 Query 241 TD---NCVALCPNCHRELHYSKNAKELIEML 268 +D CVALCPNCHRE H+S + + L Sbjct 125 SDRVWTCVALCPNCHREAHFSPDRDAINAQL 155 >ref|ZP_03016326.1| hypothetical protein BACINT_03931 [Bacteroides intestinalis DSM 17393] gb|EDV04790.1| hypothetical protein BACINT_03931 [Bacteroides intestinalis DSM 17393] Length=261 Score = 52.0 bits (123), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/92 (33%), Positives = 50/92 (54%), Gaps = 10/92 (10%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EGS + V R Y R+P+ + +++ IC+ CG + + Y GN ++ VHH++P Sbjct 162 EGSLQQALVNR----YERNPIARKKCIEKHGCICQVCGMDFSKVYGELGNGFIHVHHIVP 217 Query 233 LSS--GGA---DTTDNCVALCPNCHRELHYSK 259 +S+ G A + + V +CPNCH LH K Sbjct 218 ISALKGEAHKIEPENGLVPVCPNCHAMLHKGK 249 >ref|YP_001817436.1| restriction endonuclease-like protein [Opitutus terrae PB90-1] gb|ACB73836.1| restriction endonuclease-like protein [Opitutus terrae PB90-1] Length=261 Score = 51.6 bits (122), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/110 (28%), Positives = 52/110 (47%), Gaps = 11/110 (10%) Query 165 LIKKTLSQPEGSRKP----VEVERLQKVYVRDPMVKAWILQQSKGICENCG-KNAPFYLN 219 L++ +PEG +P V ++RL+ DP + ++ +C+ CG + Y Sbjct 139 LVRGDFEEPEGFFRPGVATVVIDRLEH----DPFARRACIEHYGSVCQACGMRFDKVYGK 194 Query 220 DGNPYLEVHHVIPLSS--GGADTTDNCVALCPNCHRELHYSKNAKELIEM 267 G ++EVH + P+S AD + LC NCHR +H A + E+ Sbjct 195 IGAGFIEVHRLRPVSRPVDSADPVKELIPLCSNCHRMIHRRSPALSVAEL 244 >ref|ZP_06707761.1| HNH endonuclease domain-containing protein [Streptomyces sp. e14] gb|EFF90883.1| HNH endonuclease domain-containing protein [Streptomyces sp. e14] Length=261 Score = 51.6 bits (122), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query 190 VRDPMVKAWILQQSKGICENCG---KNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVA 246 VR+P + ++ +S G CEN P+ G P LEV H+ + GG D +A Sbjct 164 VRNPAARRAVVIRSGGRCENPECLLPELPYRTKAGEPLLEVDHIDDHAGGGRDHPAAMIA 223 Query 247 LCPNCHRELHYSKNAKELIEML 268 LCPNCH + L E L Sbjct 224 LCPNCHSNKTHGAERAALTERL 245 >ref|ZP_05273201.1| 5-methylcytosine-specific restriction enzyme A [Clostridium difficile QCD-66c26] ref|ZP_05323591.1| 5-methylcytosine-specific restriction enzyme A [Clostridium difficile CIP 107932] ref|ZP_05357447.1| 5-methylcytosine-specific restriction enzyme A [Clostridium difficile QCD-76w55] 6 more sequence titles Length=375 Score = 51.2 bits (121), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 41/130 (31%), Positives = 62/130 (47%), Gaps = 13/130 (10%) Query 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMV 195 F A I L E+SQ ++ LN+ + +T + EG K V K Y R+P Sbjct 238 FTAEIEDDVLEEISQ----DNPLNINTINIELETEIRKEGKVKYV----YGKQYERNPRN 289 Query 196 KAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTDN----CVALCPN 250 + ++ C CG + Y + G Y+E+HH+ PLSS G ++ N V +C N Sbjct 290 RIEAIKYHGTKCIVCGFDFEKTYGDRGKGYIEIHHIKPLSSVGEESNINPKTDLVPICSN 349 Query 251 CHRELHYSKN 260 CHR +H K+ Sbjct 350 CHRMIHRKKD 359 >ref|ZP_02212388.1| hypothetical protein CLOBAR_02005 [Clostridium bartlettii DSM 16795] gb|EDQ96238.1| hypothetical protein CLOBAR_02005 [Clostridium bartlettii DSM 16795] Length=305 Score = 50.8 bits (120), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 7/98 (7%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLSSG-----GADT 240 K Y+RD V L+++ CE ++ F + Y E HH++P++ D Sbjct 193 KTYIRDRKVAMNALKKANHKCEVDSEHEVFLRRNVEVGYTESHHLVPMAYSDIFDVSLDV 252 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVN-INRLQK 277 +N V+LC +CH LHY K + ++E LY +N L K Sbjct 253 EENIVSLCSHCHNLLHYGKEFERVLEQLYYERVNHLNK 290 >ref|YP_368267.1| hypothetical protein Bcep18194_A4026 [Burkholderia sp. 383] gb|ABB07623.1| hypothetical protein Bcep18194_A4026 [Burkholderia sp. 383] Length=122 Score = 50.8 bits (120), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 20/53 (37%), Positives = 32/53 (60%), Gaps = 0/53 (0%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNC 251 +L +++ CE CG A + DG P+L+ HH+ L+ +DT N ++CPNC Sbjct 23 LLDRAETTCEACGHPATYSGADGFPFLDTHHLRKLTDSESDTVTNAFSVCPNC 75 >ref|ZP_04068325.1| HNH endonuclease [Bacillus thuringiensis IBL 4222] ref|ZP_04094136.1| HNH endonuclease [Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1] gb|EEM74182.1| HNH endonuclease [Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1] gb|EEM99879.1| HNH endonuclease [Bacillus thuringiensis IBL 4222] Length=622 Score = 50.8 bits (120), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 15/81 (18%) Query 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS 235 +RKPV DP++K L + C CG +L+ + HH++P+ + Sbjct 466 NRKPV-----------DPIIKQQTLARDDYRCRCCGTGGKAFLS----TIIFHHIVPVHA 510 Query 236 GGADTTDNCVALCPNCHRELH 256 GG DT N + LC +CH LH Sbjct 511 GGPDTVANGLTLCDSCHITLH 531 >ref|ZP_06710059.1| conserved hypothetical protein [Streptomyces sp. e14] gb|EFF93181.1| conserved hypothetical protein [Streptomyces sp. e14] Length=442 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 25/56 (44%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Query 199 ILQQSKGICEN--CGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L +S+G CEN C + +P LEV HV+ L+ GG D VALCPNCH Sbjct 328 VLGRSEGRCENPRCTGQPADVTDRRHPILEVDHVVELADGGRDHPSQMVALCPNCH 383 >gb|EBL29221.1| hypothetical protein GOS_8595230 [marine metagenome] Length=197 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 21/44 (47%), Positives = 28/44 (63%), Gaps = 0/44 (0%) Query 216 FYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259 F+ DG Y E HHV+ LS G D T+N + LC N H+++HY K Sbjct 119 FFKKDGCQYSEAHHVVQLSDKGTDFTENIMCLCANHHKQMHYGK 162 >ref|ZP_08568754.1| Putative restriction endonuclease [Rheinheimera sp. A13L] gb|EGM79648.1| Putative restriction endonuclease [Rheinheimera sp. A13L] Length=272 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 37/124 (29%), Positives = 54/124 (43%), Gaps = 23/124 (18%) Query 142 RGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQ 201 R +LS L+ TDD S ++ + + V+V ++ D M A Sbjct 128 RFQLSALTDDTDDNSYQDL-----------INQNRQATVDVYNRKRRVALDAMAHA---- 172 Query 202 QSKGICENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGA-----DTTDNCVALCPNCHREL 255 + CE + F G YLE HH+IP+S G D +N V LCP CHR L Sbjct 173 --RYRCEATSSHRLFVSKATGKNYLEAHHIIPVSLGSQFNVQLDVIENVVCLCPFCHRAL 230 Query 256 HYSK 259 H+++ Sbjct 231 HHAE 234 >ref|ZP_07388898.1| HNH endonuclease [Paenibacillus curdlanolyticus YK9] gb|EFM09527.1| HNH endonuclease [Paenibacillus curdlanolyticus YK9] Length=295 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/96 (31%), Positives = 52/96 (54%), Gaps = 4/96 (4%) Query 165 LIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKG-ICENCGKNAPFYLNDGNP 223 L+ K L++ S P + +RL +V L++ G C+ CG + F +G Sbjct 158 LVLKLLNEKYRSFSPEKKDRLISTHVDRGTSVTNALKEVLGPQCQICG-HIGFNKKNGGR 216 Query 224 YLEVHHVIPLSSGGADT--TDNCVALCPNCHRELHY 257 Y+E HH++ ++ D+ +DN + +CPNCHRE+H+ Sbjct 217 YIEAHHLVQIALKKEDSLCSDNVILVCPNCHREIHH 252 >ref|ZP_00739309.1| HNH endonuclease family protein [Bacillus thuringiensis serovar israelensis ATCC 35646] gb|EAO56436.1| HNH endonuclease family protein [Bacillus thuringiensis serovar israelensis ATCC 35646] Length=422 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 15/81 (18%) Query 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS 235 +RKPV DP++K L + C CG +L+ + HH++P+ + Sbjct 266 NRKPV-----------DPIIKQQTLARDDYRCRCCGTGGKAFLS----TIIFHHIVPVHA 310 Query 236 GGADTTDNCVALCPNCHRELH 256 GG DT N + LC +CH LH Sbjct 311 GGPDTVANGLTLCDSCHITLH 331 >gb|EDJ09760.1| hypothetical protein GOS_1755420 [marine metagenome] Length=138 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 22/56 (39%), Positives = 35/56 (62%), Gaps = 3/56 (5%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 I+ + G+C CG A F L+ G+ +E+ H +P++ G++ +N ALCP CHRE Sbjct 20 IIARQGGLCATCG--AAFDLDRGD-RVEIDHAVPVALDGSNEAENVQALCPGCHRE 72 >ref|ZP_06424640.1| Hnh [Peptostreptococcus anaerobius 653-L] gb|EFD05430.1| Hnh [Peptostreptococcus anaerobius 653-L] Length=252 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 33/98 (33%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Query 179 PVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIPLSSG- 236 P+ ER Q +Y R L++++ +CE + F N Y E HH+IPLS+ Sbjct 132 PLIAERSQYIYPRKQYESKNALKRAQYLCEVDKMHFVFKRRNSPTNYTEPHHLIPLSAHR 191 Query 237 -----GADTTDNCVALCPNCHRELHYSKNAKELIEMLY 269 D N V+LC NCH LHY K+++ LY Sbjct 192 DFPGIDLDREQNIVSLCSNCHNLLHYGLEYKDVLYDLY 229 >ref|YP_004547052.1| HNH endonuclease [Desulfotomaculum ruminis DSM 2154] gb|AEG61766.1| HNH endonuclease [Desulfotomaculum ruminis DSM 2154] Length=117 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/74 (40%), Positives = 36/74 (48%), Gaps = 15/74 (20%) Query 189 YVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA 238 Y RDP+VK W + + I CE C K P EVHHV+PLS GG Sbjct 37 YQRDPIVKKRYNRTWKRIRDRYINEHPLCERCQKEGKL-----TPAEEVHHVVPLSRGGT 91 Query 239 DTTDNCVALCPNCH 252 DN +ALC +CH Sbjct 92 HAADNLMALCTSCH 105 >ref|NP_969665.1| hypothetical protein Bd2878 [Bdellovibrio bacteriovorus HD100] emb|CAE80658.1| putative membrane protein [Bdellovibrio bacteriovorus HD100] Length=140 Score = 50.4 bits (119), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 7/94 (7%) Query 176 SRKPVEVERLQKVYVRDPMVKAWILQQ-SKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234 S P E ++ +K R+ W Q+ KG+C +CGK F D L + H+IP++ Sbjct 34 SAAPPEHQKREKAKARELRQSQWWKQELGKGLCYHCGKR--FKPAD----LTMDHLIPIA 87 Query 235 SGGADTTDNCVALCPNCHRELHYSKNAKELIEML 268 GG +NCV C +C+ + Y A+ +E L Sbjct 88 RGGKSNKNNCVPSCKDCNSKKGYKTRAEMALEEL 121 >ref|YP_003726840.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] gb|ADI74044.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] Length=401 Score = 50.1 bits (118), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 6/62 (9%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 ++ ++L + C+ C + +P LE HH++ S+GG D DN + LC CH + Sbjct 184 IRTYVLHRDNYTCQKCKNRSK------DPKLECHHIVFRSNGGTDRPDNLITLCETCHGK 237 Query 255 LH 256 LH Sbjct 238 LH 239 >ref|YP_001950539.1| HNH endonuclease [Geobacter lovleyi SZ] gb|ACD94019.1| HNH endonuclease [Geobacter lovleyi SZ] Length=281 Score = 50.1 bits (118), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/97 (35%), Positives = 46/97 (47%), Gaps = 9/97 (9%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVI 231 PEG+ V V + Y R P+ +A + +C CG + Y G Y+EVHH I Sbjct 177 PEGACIKVIVNK----YERSPVNRAVCIAVYGTVCHVCGFDFGKVYGQIGKGYIEVHHRI 232 Query 232 PLSSGGA----DTTDNCVALCPNCHRELHYSKNAKEL 264 P+S GA D + V LC NCH +H + EL Sbjct 233 PVSKMGASYVIDPIRDLVPLCSNCHSAVHRTDPPVEL 269 >gb|EBU48765.1| hypothetical protein GOS_7107064 [marine metagenome] Length=127 Score = 49.7 bits (117), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 22/56 (39%), Positives = 35/56 (62%), Gaps = 3/56 (5%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 I+ + G+C CG A F L+ G+ +E+ H +P++ G++ +N ALCP CHRE Sbjct 9 IIARQGGLCATCG--AAFDLDRGD-RVEIDHAVPVALDGSNEAENVQALCPGCHRE 61 >ref|YP_004464373.1| HNH endonuclease [Mahella australiensis 50-1 BON] gb|AEE97551.1| HNH endonuclease [Mahella australiensis 50-1 BON] Length=497 Score = 49.7 bits (117), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 35/68 (51%), Gaps = 9/68 (13%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 ++ +I+ + +G C CGK +L HH++P S GG+DT N LC CH + Sbjct 219 MREYIIAKQEGKCLLCGKRKIEHL---------HHIVPRSKGGSDTYKNIAGLCGKCHEK 269 Query 255 LHYSKNAK 262 +H AK Sbjct 270 VHKDPKAK 277 >ref|ZP_08167457.1| hypothetical protein HMPREF9402_0852 [Turicibacter sp. HGF1] gb|EGC92233.1| hypothetical protein HMPREF9402_0852 [Turicibacter sp. HGF1] Length=316 Score = 49.7 bits (117), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/75 (34%), Positives = 40/75 (53%), Gaps = 5/75 (6%) Query 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTD 242 L ++Y RD + + Q+ K +C+ CGK ++++ Y E HH+ PL G D + Sbjct 195 LTRIY-RDTKIVRALKQEYKDVCQICGKT--IFISENKNYSEGHHIKPLGGIHCGPDIKE 251 Query 243 NCVALCPNCHRELHY 257 N + LCPN H E Y Sbjct 252 NIIVLCPNHHTEFDY 266 >ref|YP_002601669.1| putative 5-methylcytosine-specific restriction enzyme A [Desulfobacterium autotrophicum HRM2] gb|ACN13505.1| putative 5-methylcytosine-specific restriction enzyme A [Desulfobacterium autotrophicum HRM2] Length=375 Score = 49.7 bits (117), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 9/99 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EG+++ V + + Y RD + ++ C+ CG + Y G Y+ VHH+IP Sbjct 275 EGAKQTVTINK----YERDHNARKACIEYHGYNCKVCGFDFEKTYGELGRNYIHVHHLIP 330 Query 233 LSSGGADTTDN----CVALCPNCHRELHYSKNAKELIEM 267 LS G + + N + +CPNCH LH S+N +L + Sbjct 331 LSKIGKEYSINPQTDLIPVCPNCHAMLHKSENPNDLYSL 369 >gb|ECB21691.1| hypothetical protein GOS_5236864 [marine metagenome] Length=307 Score = 49.3 bits (116), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 13/106 (12%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPF-YLNDGNPYLEVHHVIP 232 EG RK R +VR+P + + +Q CE CG + Y + G Y+E HH P Sbjct 202 EGKRK----RRESYFFVRNPKLAKQVKEQRGYKCEACGFDFKLKYGDRGAKYIECHHENP 257 Query 233 LSSGGADTTDNCVA--------LCPNCHRELHYSKNAKELIEMLYV 270 LS D + LC NCHR +H ++ A + ++L + Sbjct 258 LSERSEKEWDKNLTTSVNEVKLLCSNCHRMIHRTRPAMKFKDLLNI 303 >ref|YP_003239728.1| HNH endonuclease [Ammonifex degensii KC4] gb|ACX52878.1| HNH endonuclease [Ammonifex degensii KC4] Length=387 Score = 49.3 bits (116), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 24/57 (42%), Positives = 29/57 (50%), Gaps = 9/57 (15%) Query 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNA 261 G C CG L+ HH++P S GG DT +N V LC CHRELH + A Sbjct 185 GACVLCGSTR---------RLQRHHLVPRSKGGTDTPENQVLLCAECHRELHAGEAA 232 >ref|YP_001321783.1| HNH endonuclease [Alkaliphilus metalliredigens QYMF] gb|ABR50124.1| HNH endonuclease [Alkaliphilus metalliredigens QYMF] Length=124 Score = 49.3 bits (116), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 49/94 (52%), Gaps = 15/94 (15%) Query 164 KLIKKTLSQPEGSRKPVEVERLQKVY--VRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221 K++ K +Q + R P +R + + +RD +KA L CE C +N + Sbjct 29 KVVTKRYNQYQ--RDPASNKRYGRSWKRIRDRYIKAHPL------CEECDRNGRIKAAE- 79 Query 222 NPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255 EVHH++PLS GG + T N +ALC +CH ++ Sbjct 80 ----EVHHILPLSKGGGNETSNLMALCKSCHSKI 109 >gb|EBM37869.1| hypothetical protein GOS_8419518 [marine metagenome] Length=162 Score = 49.3 bits (116), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 26/131 (19%) Query 155 ESLLNMRVSKLIKKTLSQPEGS------RKPVEVERLQKVYVRDPMVKAW---------- 198 E +N++VSK TLS E + R +E+ YVRD VK+ Sbjct 18 EHEINLKVSK----TLSGKEHNGLTRQQRIQLEIADKHASYVRDTEVKSLLELSSRTVSK 73 Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 IL++ K C CG + +G ++HH+ +GG D N +CPNCHR +H Sbjct 74 ILKRMKLGCSCCG-----WFVEGVA-CDIHHINEKKNGGNDEHTNLTYVCPNCHRLIHSD 127 Query 259 KNAKELIEMLY 269 K KE + LY Sbjct 128 KIDKEKLVNLY 138 >ref|YP_097917.1| hypothetical protein BF0634 [Bacteroides fragilis YCH46] dbj|BAD47383.1| hypothetical protein [Bacteroides fragilis YCH46] Length=216 Score = 49.3 bits (116), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 9/104 (8%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 PE +R ++ R + +R+ + + + +C+ CG + + Y EVHH+ P Sbjct 96 PEEAR---QIRREIEAILRNQKLVDELKIRYNNVCQICG--TQIKIGENKYYSEVHHIWP 150 Query 233 LSS--GGADTTDNCVALCPNCHRELHYSKNA--KELIEMLYVNI 272 L G+DT DN V +CPNCH L Y KE+ ++L NI Sbjct 151 LGKPHNGSDTLDNMVCVCPNCHTLLDYKAIHLNKEIFKVLKHNI 194 >ref|ZP_01170179.1| hypothetical protein B14911_16960 [Bacillus sp. NRRL B-14911] gb|EAR67223.1| hypothetical protein B14911_16960 [Bacillus sp. NRRL B-14911] Length=339 Score = 49.3 bits (116), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 15/111 (13%) Query 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229 S EG RK V V VY R+P+ + ++ C+ C N Y G ++ VHH Sbjct 232 SLEEGKRKSVTV----NVYERNPIARKLCIEHYGLQCQVCNLNFEDTYGGVGKDFIHVHH 287 Query 230 VIPLSSGGADTTDN----CVALCPNCHRELHYSKNAKELIEMLYVNINRLQ 276 +IPL D N + +CPNCH LH +N +Y+++ +L+ Sbjct 288 IIPLYEIQQDYEVNPILDLIPVCPNCHAMLHRKENG------IYLSVEQLK 332 >ref|ZP_05984078.1| 5-methylcytosine-specific restriction enzyme A [Neisseria subflava NJ9703] gb|EFC53315.1| 5-methylcytosine-specific restriction enzyme A [Neisseria subflava NJ9703] Length=255 Score = 48.9 bits (115), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 38/108 (35%), Positives = 55/108 (50%), Gaps = 10/108 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EGS + V V R Y RDP + L++ C C N FY G ++ VHH+ P Sbjct 150 EGSVQQVMVNR----YERDPKAREACLKKYGYNCSVCNFNFEDFYGEIGKNFIHVHHLTP 205 Query 233 LSSGGADTTD---NCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 +S+ G T+ + +CPNCH LH + N + IE L + I ++QK Sbjct 206 VSNNGERYTNPEKDLRPVCPNCHAMLHKT-NRPQRIEDLKLLI-KMQK 251 >gb|EBU48867.1| hypothetical protein GOS_7106928 [marine metagenome] Length=240 Score = 48.5 bits (114), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 43/94 (45%), Gaps = 19/94 (20%) Query 182 VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN-----DGNPYLEVHHVIPLSSG 236 VER QK+ VR +L+Q +CE CG + Y D P L+VHH PL Sbjct 143 VERAQKIRVR-------VLEQRGAVCEACGLDPAVYYQFSGRVDQYP-LDVHHSKPLRDL 194 Query 237 GADTT------DNCVALCPNCHRELHYSKNAKEL 264 + D+ + LCP CHR +H + +L Sbjct 195 AEGESRRYRIPDDFLVLCPTCHRMIHKLSDPSDL 228 >gb|EBA98496.1| hypothetical protein GOS_308273 [marine metagenome] Length=195 Score = 48.5 bits (114), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/53 (45%), Positives = 31/53 (58%), Gaps = 2/53 (3%) Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 P E+ H +PL SGG D N ALCPNCH+E +N K+ L+ +IN L Sbjct 122 PAFEIDHKVPLESGGLDELSNLWALCPNCHKEKTRRENLKK--HRLFEDINTL 172 >gb|ECD84752.1| hypothetical protein GOS_5295183 [marine metagenome] Length=206 Score = 48.5 bits (114), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 11/74 (14%) Query 207 CENCGKNAPFYLN-DGNPYLEVHHVIPLSSGGA--------DTTDNCVALCPNCHRELHY 257 CE ++ F D Y E HH+IP S D N V+LCPNCHR++H+ Sbjct 109 CEISSSHSTFLRKKDNQQYTEAHHLIPYSQFDEYAEKGLSIDRPINIVSLCPNCHRKIHH 168 Query 258 SKNA--KELIEMLY 269 N +ELI +LY Sbjct 169 GTNTDIRELISILY 182 >ref|YP_341779.1| putative HNH endonuclease [Pseudoalteromonas haloplanktis TAC125] emb|CAI89333.1| putative HNH endonuclease [Pseudoalteromonas haloplanktis TAC125] Length=420 Score = 48.5 bits (114), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA++LQ+ C++ K N L VHH + S GG D N +ALC CH + Sbjct 184 VKAYVLQRDNYKCQSGRKT------KHNAKLHVHHKVFRSQGGTDALSNLIALCETCHND 237 Query 255 LHYSK 259 LH K Sbjct 238 LHVGK 242 >ref|ZP_00517558.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM49350.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=276 Score = 48.5 bits (114), Expect = 0.001, Method: Compositional matrix adjust. Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 12/115 (10%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKA 197 G+ + + T + L + +++ + TL +PE S P + + + Y P A Sbjct 155 GKQGKWTFQTREYVLYHHTETEIKRHTLVKPESS--PYDGNWTYWSKRRGTYTGTPARVA 212 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL +CH Sbjct 213 KLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 262 >ref|ZP_07673316.1| product McrA [Erysipelotrichaceae bacterium 3_1_53] gb|EFP59678.1| product McrA [Erysipelotrichaceae bacterium 3_1_53] Length=287 Score = 48.5 bits (114), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 8/104 (7%) Query 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDG-NPYLEVH 228 +++ +KP E + DP KA L+ CE + F G + Y+E H Sbjct 153 IAEQRKHKKPCENTTVHNRVATDPHFKATCLENHNYQCEISKDHETFSNTTGLHQYMECH 212 Query 229 HVIPLSSGG------ADTTDNCVALCPNCHRELHY-SKNAKELI 265 H+IP+ + D N V LCP CH ++HY +++KE + Sbjct 213 HLIPMKAQKDFPDLWLDDLFNLVCLCPLCHAQIHYGDRSSKEAV 256 >ref|YP_090375.1| hypothetical protein BLi00747 [Bacillus licheniformis ATCC 14580] ref|YP_077970.2| hypothetical protein BL02333 [Bacillus licheniformis ATCC 14580] gb|AAU39682.1| putative protein [Bacillus licheniformis ATCC 14580] gb|AAU22332.2| McrA [Bacillus licheniformis ATCC 14580] Length=140 Score = 48.1 bits (113), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/108 (26%), Positives = 55/108 (50%), Gaps = 8/108 (7%) Query 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVH 228 +SQ +P+ + Q+ + R+ + + + S CE + F N PY+E H Sbjct 5 VSQKRKRPQPIINQGGQRHWTRNASLASKAMMLSNYTCEIDHTHRTFISKSTNMPYVECH 64 Query 229 HVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKN--AKELIEMLY 269 H++P++ D N V+LCP+CHR +HY ++ +++++ LY Sbjct 65 HLVPIAKQEGFKYDLDQLANLVSLCPHCHRLIHYGQDEEKEKMLKKLY 112 >ref|ZP_07399124.1| HNH endonuclease domain protein [Peptoniphilus duerdenii ATCC BAA-1640] gb|EFM25926.1| HNH endonuclease domain protein [Peptoniphilus duerdenii ATCC BAA-1640] Length=122 Score = 48.1 bits (113), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 43/86 (50%), Gaps = 15/86 (17%) Query 181 EVERLQKVYVRDPMV-----KAWILQQSK-----GICENCGKNAPFYLNDGNPYLEVHHV 230 E R + Y RDP KAW + + + +CE C K N EVHH+ Sbjct 29 EYNRNYEKYKRDPKTHKRYGKAWRVIRKRYVAEHPLCEMCLKE-----NKMTKVEEVHHI 83 Query 231 IPLSSGGADTTDNCVALCPNCHRELH 256 +PLS GG + DN ++LC +CH ++H Sbjct 84 LPLSRGGTNDEDNLMSLCKSCHSKIH 109 >ref|YP_003726457.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] gb|ADI73661.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] Length=407 Score = 48.1 bits (113), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 6/65 (9%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 ++ ++L + C+ C + +P LE HH++ S GG + DN + LC CH + Sbjct 184 IRTYVLHRDNYTCQKCKNRSK------DPKLECHHIVFRSKGGTNRPDNLITLCETCHGK 237 Query 255 LHYSK 259 LH K Sbjct 238 LHNGK 242 >ref|YP_003727124.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] gb|ADI74328.1| HNH endonuclease [Methanohalobium evestigatum Z-7303] Length=407 Score = 48.1 bits (113), Expect = 0.002, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 6/62 (9%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 ++ ++L + C+ C + +P LE HH+I S GG D +N + LC CH + Sbjct 184 IRIYVLHRDDYTCQKCKNKSK------DPKLECHHIIFRSKGGTDRPNNLITLCETCHSK 237 Query 255 LH 256 LH Sbjct 238 LH 239 >ref|ZP_00513911.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM53114.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=584 Score = 48.1 bits (113), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 12/115 (10%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKA 197 G+ + + T + L + +++ + TL +PE S P + + + Y P A Sbjct 463 GKQGKWTFQTREYVLYHHTETEIKRHTLVKPESS--PYDGNWTYWSKRRGTYTGTPARVA 520 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL +CH Sbjct 521 KLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 570 >ref|ZP_08324079.1| HNH endonuclease domain protein [Parasutterella excrementihominis YIT 11859] gb|EGG53416.1| HNH endonuclease domain protein [Parasutterella excrementihominis YIT 11859] Length=291 Score = 48.1 bits (113), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/110 (32%), Positives = 53/110 (48%), Gaps = 12/110 (10%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVI 231 PEG + R Y R P ++A +L + C CG + Y G ++EVHH+I Sbjct 186 PEGKPRTFFTYR----YERSPKLRAAVLNKFGYKCAVCGFDFEKIYGQLGKNFIEVHHMI 241 Query 232 PLSSGGADT-TDNCVALCPNCHRELH--YSKNAKE----LIEMLYVNINR 274 P+S + +N LC NCHR +H YS E I++L + IN+ Sbjct 242 PVSEKERENDVNNLRPLCSNCHRMIHRLYSSLEPEEYAGAIDLLKLTINK 291 >ref|ZP_07758536.1| HNH endonuclease domain protein [Enterococcus faecalis TX0470] gb|EFQ72188.1| HNH endonuclease domain protein [Enterococcus faecalis TX0470] Length=153 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 27/111 (24%) Query 144 ELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQS 203 ++ +L + D+E+ N++ ++ + ++K ++ Q+V+ RD Sbjct 53 DIEQLQKEFDNETFFNIKFKRMYQ------TNAKKWKKIS--QEVFERDAYT-------- 96 Query 204 KGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 C+ CGK LEV HVIP S GG+D DN V C C+R+ Sbjct 97 ---CKYCGKIGGI--------LEVDHVIPFSKGGSDELDNLVCACRKCNRQ 136 >ref|ZP_08044848.1| HNH endonuclease domain protein [Haladaptatus paucihalophilus DX253] gb|EFW91652.1| HNH endonuclease domain protein [Haladaptatus paucihalophilus DX253] Length=234 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 4/87 (4%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 PEG+ P V R + R+ V + ++ C+ CG +G Y E HH+ P Sbjct 103 PEGTDDPERVRRTVETVTRNRKVVERLKERYDYECQLCGTRRRRSRTEG--YAEAHHIEP 160 Query 233 LSSG--GADTTDNCVALCPNCHRELHY 257 L G D +N + +CPN HR+L Y Sbjct 161 LGGPHFGPDMPENLLVVCPNHHRDLDY 187 >ref|ZP_00518164.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM48744.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=183 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 12/115 (10%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKA 197 G+ + + T + L + +++ + TL +PE S P + + + Y P A Sbjct 62 GKQGKWTFQTREYVLYHHTETEIKRHTLVKPESS--PYDGNWTYWSKRRGTYTGTPARVA 119 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL +CH Sbjct 120 KLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 169 >ref|ZP_08107522.1| HNH endonuclease [Clostridium symbiosum WAL-14673] gb|EGB18631.1| HNH endonuclease [Clostridium symbiosum WAL-14673] Length=119 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 18/94 (19%) Query 173 PEGSRKPVEVERLQKVYVRDPMVK-----AW-----ILQQSKGICENCGKNAPFYLNDGN 222 PE +K E +R +K Y RDP K AW + +CE C +N + Sbjct 24 PEHEKK--EAKRYEK-YDRDPNAKRRYGRAWKRIRDSYAAAHPLCERCLENGVY-----T 75 Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 P ++HHV PLS GG +N +ALC +CH ++H Sbjct 76 PTEQIHHVKPLSQGGTHDRENLMALCKSCHAKIH 109 >ref|ZP_07289254.1| HNH endonuclease [Streptomyces sp. C] gb|EFL17623.1| HNH endonuclease [Streptomyces sp. C] Length=274 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 3/55 (5%) Query 207 CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNCHRELHYS 258 CE CG + A Y G Y+E HHV+PL G TT + +C NCHR +H S Sbjct 182 CEACGFDFALVYGERGEGYIECHHVVPLHEAGEGTTKLSDLALICSNCHRMIHRS 236 >ref|YP_003238831.1| HNH endonuclease [Ammonifex degensii KC4] gb|ACX51981.1| HNH endonuclease [Ammonifex degensii KC4] Length=234 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/32 (59%), Positives = 23/32 (71%), Gaps = 0/32 (0%) Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 L+VHH++P S GG DT N V LC CHR+LH Sbjct 196 LQVHHLVPRSKGGTDTPANLVVLCRECHRKLH 227 >ref|YP_003220843.1| endonuclease-like protein [Escherichia coli O103:H2 str. 12009] ref|YP_003233391.1| endonuclease-like protein [Escherichia coli O111:H- str. 11128] dbj|BAI29709.1| endonuclease-like protein [Escherichia coli O103:H2 str. 12009] dbj|BAI34840.1| endonuclease-like protein [Escherichia coli O111:H- str. 11128] Length=246 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS---- 235 ++ERL Y RDP + + C CG N Y + G Y++VHH+ PL Sbjct 144 QLERLATYYERDPKARQACIDAHGYTCHICGFNFEKVYGSIGKNYIQVHHIKPLHHIAKY 203 Query 236 GGADTTDNCVALCPNCHRELH 256 D ++ + LC NCH +H Sbjct 204 HKVDPVNDLIPLCANCHVMIH 224 >gb|EGB62750.1| HNH endonuclease [Escherichia coli M863] Length=246 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 5/81 (6%) Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS---- 235 ++ERL Y RDP + + C CG N Y + G Y++VHH+ PL Sbjct 144 QLERLATYYERDPKARQACIDAHGYTCHICGFNFEKVYGSIGKNYIQVHHIKPLHHIAKY 203 Query 236 GGADTTDNCVALCPNCHRELH 256 D ++ + LC NCH +H Sbjct 204 HKVDPVNDLIPLCANCHVMIH 224 >ref|ZP_07932753.1| HNH endonuclease [Anaerostipes sp. 3_2_56FAA] gb|EFV21129.1| HNH endonuclease [Anaerostipes sp. 3_2_56FAA] Length=213 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 17/30 (56%), Positives = 21/30 (70%), Gaps = 0/30 (0%) Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P++EVHH+IP S GG DT +N LC CH Sbjct 25 PFVEVHHIIPQSEGGEDTIENAAPLCSRCH 54 >ref|ZP_07831699.1| HNH endonuclease domain protein [Clostridium sp. HGF2] gb|EFR38817.1| HNH endonuclease domain protein [Clostridium sp. HGF2] Length=119 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/94 (35%), Positives = 47/94 (50%), Gaps = 18/94 (19%) Query 173 PEGSRKPVEVERLQKVYVRDPMVK-----AW-----ILQQSKGICENCGKNAPFYLNDGN 222 PE +K E +R +K Y RDP K AW + +CE C +N + Sbjct 24 PEHEKK--EAKRYEK-YDRDPATKRRYGRAWKRIRDSYAAAHPLCEMCLENGVY-----T 75 Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 P ++HHV PLS GG +N +ALC +CH ++H Sbjct 76 PTEQIHHVKPLSQGGTHDRENLMALCKSCHAKIH 109 >gb|EBK30658.1| hypothetical protein GOS_8754332 [marine metagenome] Length=121 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 8/78 (10%) Query 200 LQQSKGICENCGKNAPFY-LNDGNPYLEVHHVIPLS-----SGGADTTDNCVALCPNCHR 253 ++ S+ +CEN ++ F G ++E HH+IP+ D +N ++LCPNCH Sbjct 15 IEDSQFLCENDPNHSTFISRKSGKQFMEAHHLIPMEFYDHFQYSIDVPENIISLCPNCHS 74 Query 254 ELHYSK--NAKELIEMLY 269 HYS+ ++IE Y Sbjct 75 IFHYSEINFRNKIIEKFY 92 >ref|YP_003376869.1| hypothetical protein XALc_2397 [Xanthomonas albilineans GPE PC73] ref|YP_003377101.1| hypothetical protein XALc_2629 [Xanthomonas albilineans GPE PC73] emb|CBA16877.1| putative phage-related protein [Xanthomonas albilineans] emb|CBA17107.1| putative phage-related protein [Xanthomonas albilineans] Length=121 Score = 47.8 bits (112), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 35/58 (60%), Gaps = 5/58 (8%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 ++A+++Q+ +G+C+ C ++ P + V H++P S GG D +NC A+C CH Sbjct 54 LRAFVMQRDQGLCQPCKQSGRL-----TPAVAVDHIVPKSQGGTDHPNNCQAICHRCH 106 >ref|ZP_08001265.1| hypothetical protein HMPREF1012_02303 [Bacillus sp. BT1B_CT2] gb|EFV71664.1| hypothetical protein HMPREF1012_02303 [Bacillus sp. BT1B_CT2] Length=371 Score = 47.4 bits (111), Expect = 0.002, Method: Compositional matrix adjust. Identities = 26/97 (26%), Positives = 48/97 (49%), Gaps = 6/97 (6%) Query 170 LSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVH 228 ++Q +P+ + Q+ + R+ + + + S CE + F N PY+E H Sbjct 236 INQKRERPQPIINQGGQRQWTRNASLASKAMMLSNYTCEIDHSHQTFISKSTNKPYVECH 295 Query 229 HVIPLSSG-----GADTTDNCVALCPNCHRELHYSKN 260 H++P++ D N V+LCP+CHR +HY ++ Sbjct 296 HLVPIAKQEKFKYDLDQLANLVSLCPHCHRLIHYGQD 332 >ref|ZP_05596803.1| predicted protein [Enterococcus faecalis T11] gb|EEU91597.1| predicted protein [Enterococcus faecalis T11] Length=288 Score = 47.4 bits (111), Expect = 0.002, Method: Compositional matrix adjust. Identities = 21/46 (45%), Positives = 26/46 (56%), Gaps = 5/46 (10%) Query 224 YLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELHYSKNAKEL 264 Y+E HH+IPLS+ D T N LCP CHR +HY K +L Sbjct 212 YMETHHIIPLSAQRYYKNKLDCTANLSCLCPTCHRSIHYGKKEDKL 257 >gb|EBL67753.1| hypothetical protein GOS_8532417 [marine metagenome] Length=132 Score = 47.4 bits (111), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/46 (41%), Positives = 30/46 (65%), Gaps = 5/46 (10%) Query 224 YLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNAKEL 264 Y+E HHV+P+S+ A D +N V+LCPNCH+++H N ++ Sbjct 53 YVEAHHVVPISATEAFQVDLDVIENIVSLCPNCHKKIHLGDNQSKI 98 >ref|YP_004113653.1| HNH endonuclease [Desulfurispirillum indicum S5] gb|ADU67097.1| HNH endonuclease [Desulfurispirillum indicum S5] Length=251 Score = 47.4 bits (111), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 9/93 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EG+ K + V Y R+ +A ++ C C + A FY + G Y+ VHHV+P Sbjct 145 EGASKVIAV----NTYERNAEARAKCIKHHGYECAVCKFDFAAFYGSIGEKYIHVHHVVP 200 Query 233 LSSGGADTTDN----CVALCPNCHRELHYSKNA 261 LS G + N V +CPNCH +H ++ A Sbjct 201 LSEIGREYILNPIKDLVPICPNCHAIIHRTRPA 233 >gb|ECD32245.1| hypothetical protein GOS_3904965 [marine metagenome] Length=294 Score = 47.4 bits (111), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 9/81 (11%) Query 175 GSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLS 234 G RK VE L+ RDP+ K IL++ +G C G N L+ H+IP++ Sbjct 164 GPRKKSTVEVLRAE--RDPLFKFNILKRFQGACLVTGINV-------TEMLDAAHIIPVA 214 Query 235 SGGADTTDNCVALCPNCHREL 255 SGG ++++N + L + HR L Sbjct 215 SGGTESSENGMLLSASAHRAL 235 >ref|ZP_08148126.1| hypothetical protein HMPREF9417_0867 [Haemophilus parainfluenzae ATCC 33392] gb|EGC72450.1| hypothetical protein HMPREF9417_0867 [Haemophilus parainfluenzae ATCC 33392] Length=212 Score = 47.4 bits (111), Expect = 0.003, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 9/94 (9%) Query 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN--DGNPYLEVHHVIPLSSG-----G 237 + Y RD V L +++ +CE + F D Y E HH+IPLS Sbjct 95 ISSAYKRDINVARNALIRARFLCEYDESDRVFLRKGCDEIYYTEAHHLIPLSEHNDFEYS 154 Query 238 ADTTDNCVALCPNCHRELHYSK--NAKELIEMLY 269 D +N V+LC +CH LHY + + KE+++ LY Sbjct 155 LDIEENVVSLCSHCHNLLHYGRYEDKKEILQKLY 188 >ref|NP_680905.1| maturase; reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC07667.1| maturase; reverse transcriptase [Thermosynechococcus elongatus BP-1] Length=562 Score = 47.4 bits (111), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 PE + E ++L++ + ++ + ++ GIC CG + + E+HH++P Sbjct 469 PEWAEYFEERKKLKEAPAQYRRIRRELWKKQGGICPVCGGEI-----EQDMLTEIHHILP 523 Query 233 LSSGGADTTDNCVALCPNCHRELH 256 GG+D DN V + NCH+++H Sbjct 524 KHKGGSDDLDNLVLIHANCHKQVH 547 >ref|ZP_06945735.1| HNH endonuclease domain protein [Finegoldia magna ATCC 53516] gb|EFH93790.1| HNH endonuclease domain protein [Finegoldia magna ATCC 53516] Length=132 Score = 47.0 bits (110), Expect = 0.003, Method: Compositional matrix adjust. Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 15/86 (17%) Query 181 EVERLQKVYVRDPMV-----KAWILQQSK-----GICENCGKNAPFYLNDGNPYLEVHHV 230 E R + Y RDP K W + + + +CE C K N EVHH+ Sbjct 43 EYNRNYEKYKRDPKTHKRYGKTWRIIRKRYVAEHPLCEMCLKE-----NRMTKVEEVHHI 97 Query 231 IPLSSGGADTTDNCVALCPNCHRELH 256 +PLS GG + DN ++LC +CH ++H Sbjct 98 LPLSRGGTNNEDNLMSLCKSCHSKIH 123 >gb|EGC81795.1| HNH endonuclease domain protein [Anaerococcus prevotii ACS-065-V-Col13] Length=134 Score = 47.0 bits (110), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 15/78 (19%) Query 189 YVRDPMV-----KAWILQQSK-----GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA 238 Y RDP KAW + + + +CE C K N EVHH++PLS GG Sbjct 51 YKRDPNTHKRYGKAWRIIRKRYVAEHPLCEMCLKE-----NRMTKVEEVHHILPLSRGGT 105 Query 239 DTTDNCVALCPNCHRELH 256 + DN ++LC +CH ++H Sbjct 106 NDEDNLMSLCKSCHSKIH 123 >ref|YP_120439.1| putative endonuclease [Nocardia farcinica IFM 10152] dbj|BAD59075.1| putative endonuclease [Nocardia farcinica IFM 10152] Length=123 Score = 47.0 bits (110), Expect = 0.003, Method: Compositional matrix adjust. Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query 202 QSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNCHRELHYS 258 S+ CE CG + Y G Y+E HH++PL G T + V LC NCHR +H+ Sbjct 34 HSRVFCEVCGFDFEAVYGERGAGYIECHHIVPLHVSGETVTKLSDLVLLCSNCHRMIHHG 93 Query 259 K---NAKELIEMLYVN 271 + +EL E++ V+ Sbjct 94 SRWLSPEELREVVQVS 109 >ref|YP_004199626.1| HNH endonuclease [Geobacter sp. M18] gb|ADW14350.1| HNH endonuclease [Geobacter sp. M18] Length=254 Score = 47.0 bits (110), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 5/79 (6%) Query 187 KVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSS----GGADTT 241 K Y R+P+ + ++ +C CG N Y G+ Y+EVHHV P+S+ D Sbjct 160 KRYERNPVNRLEAIRYHGLVCNVCGFNFEEVYGERGSGYIEVHHVEPISTYDGEQPVDPK 219 Query 242 DNCVALCPNCHRELHYSKN 260 + + +C NCHR +H + N Sbjct 220 TDLITVCSNCHRMIHRNPN 238 >ref|ZP_01628404.1| hypothetical protein N9414_14925 [Nodularia spumigena CCY9414] gb|EAW46983.1| hypothetical protein N9414_14925 [Nodularia spumigena CCY9414] Length=394 Score = 47.0 bits (110), Expect = 0.004, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 5/56 (8%) Query 206 ICENCGKNAPFYLNDGNPYLEVHHVIPLSS-----GGADTTDNCVALCPNCHRELH 256 +C+ C N + LE+HH++PLSS G + ++ V LCPNCHR +H Sbjct 305 VCDMCSCNTRHRYPWTDNLLEIHHLLPLSSAITVTGEGTSLEDVVGLCPNCHRSVH 360 >ref|ZP_00514209.1| RNA-directed DNA polymerase [Crocosphaera watsonii WH 8501] gb|EAM52047.1| RNA-directed DNA polymerase [Crocosphaera watsonii WH 8501] Length=594 Score = 47.0 bits (110), Expect = 0.004, Method: Compositional matrix adjust. Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 +Y PM + +L++ KGIC C ++ F +D +EV H+IP S GG D DN AL Sbjct 504 IYTGTPMRVSKLLKKQKGICPICKQH--FTPDD---LIEVDHIIPKSKGGKDRYDNLQAL 558 Query 248 CPNCH 252 +CH Sbjct 559 HRHCH 563 >ref|YP_003238553.1| HNH endonuclease [Ammonifex degensii KC4] gb|ACX51703.1| HNH endonuclease [Ammonifex degensii KC4] Length=388 Score = 47.0 bits (110), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/52 (42%), Positives = 27/52 (51%), Gaps = 9/52 (17%) Query 205 GICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 G C CG L+ HH++P S GG DT +N V LC CHR+LH Sbjct 185 GACVLCGSTR---------RLQRHHLVPRSKGGTDTPENQVLLCAECHRKLH 227 >ref|YP_003534492.1| HNH endonuclease domain-containing protein [Haloferax volcanii DS2] gb|ADE03339.1| HNH endonuclease domain protein [Haloferax volcanii DS2] Length=498 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 43/137 (31%), Positives = 57/137 (41%), Gaps = 23/137 (16%) Query 132 YSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVE-------- 183 Y+ S++ I EL L Q DE +K ++T P PV+VE Sbjct 321 YNPSYFEEIWSDEL--LLQENRDED------TKTRQRTDPFPREDFDPVQVEPELYEDIG 372 Query 184 RLQKVY---VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGA 238 R Q V RD V + + C+ CG NDG Y EVHH++PL G Sbjct 373 RYQTVLDRVRRDREVVNELKRLYDDKCQVCGTT--LLRNDGTRYSEVHHIVPLGEPHSGP 430 Query 239 DTTDNCVALCPNCHREL 255 D N + LCPN H + Sbjct 431 DKRSNMLVLCPNHHTDF 447 >gb|AEG70099.1| conserved hypothetical protein [Ralstonia solanacearum Po82] Length=233 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 9/96 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EG+ K V V + Y RDP ++ +Q K IC CG + Y G ++ VHH+ Sbjct 126 EGAAKQVVVNQ----YERDPKARSACIQHWKPICYVCGFDFHKTYGEMGRGFIHVHHLTD 181 Query 233 LSSGGAD-TTDNCVAL---CPNCHRELHYSKNAKEL 264 ++S G + D C L CPNCH LH + A ++ Sbjct 182 IASIGKEYQVDPCKDLRPVCPNCHAMLHTQRPALDI 217 >gb|EGF39969.1| hypothetical protein VP10329_22848 [Vibrio parahaemolyticus 10329] Length=258 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 65/158 (41%), Gaps = 22/158 (13%) Query 104 QAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVS 163 + YF+ GR+++ ++I I D W EL+ + D+E + Sbjct 94 ETYFTFHGREDMDFAWHKQQIQIAC-----DCNWVD----ELNRRNIDIDNE----FSYA 140 Query 164 KLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGN 222 I + S EGS+K + V Y R + ++ C CG N FY Sbjct 141 DEITEPTSVVEGSKKTITV----NAYERSTFARNECIRLKGDSCIVCGFNFGKFYGEKAE 196 Query 223 PYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELH 256 ++ VHH++PL D ++ V +CPNCH LH Sbjct 197 GFIHVHHLVPLHEINEEYEVDPEEHLVPVCPNCHAMLH 234 >ref|ZP_00514520.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM52358.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=214 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 37/128 (28%), Positives = 62/128 (48%), Gaps = 16/128 (12%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEV-----ERLQKVYVRDPMVKA 197 G+ + + T L + +++ + TL +PE S P++ + + Y P + Sbjct 76 GKHGKWTFQTGKTVLYHHAETEIKRHTLVKPESS--PLDGNWTYGRKRRGTYTGTPTRVS 133 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHY 257 +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL HR HY Sbjct 134 KLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNLQAL----HRHCHY 184 Query 258 SKNAKELI 265 K+ + + Sbjct 185 VKSKNDYL 192 >ref|YP_735330.1| hypothetical protein Shewmr4_3203 [Shewanella sp. MR-4] gb|ABI40273.1| hypothetical protein Shewmr4_3203 [Shewanella sp. MR-4] Length=295 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 8/65 (12%) Query 221 GNPYLEVHHVIPLSSG-----GADTTDNCVALCPNCHRELHYSKNAK--ELIEMLY-VNI 272 G ++E HH++P++ D N V LCPNCHR +HY+++ EL+ Y I Sbjct 215 GKAFVEAHHLVPVAKSPDFDVSLDVEPNIVVLCPNCHRAIHYAESQYKIELLTRFYNQRI 274 Query 273 NRLQK 277 N L++ Sbjct 275 NELRQ 279 >ref|ZP_06560205.1| HNH endonuclease domain protein [Megasphaera genomosp. type_1 str. 28L] gb|EFD93910.1| HNH endonuclease domain protein [Megasphaera genomosp. type_1 str. 28L] Length=90 Score = 46.6 bits (109), Expect = 0.004, Method: Composition-based stats. Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 13/77 (16%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH-- 252 VK ++++ G+C CG A ++VHHV S GG D NCV LC CH Sbjct 9 VKRLVIKRDNGLCVLCGALA----------VDVHHVKFRSQGGKDDVRNCVCLCRKCHDM 58 Query 253 -RELHYSKNAKELIEML 268 LH +AKE+ ML Sbjct 59 AHGLHKYISAKEVKAML 75 >ref|ZP_01622212.1| hypothetical protein L8106_02712 [Lyngbya sp. PCC 8106] gb|EAW35851.1| hypothetical protein L8106_02712 [Lyngbya sp. PCC 8106] Length=280 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/60 (40%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P K ++L++ KG C CG + DG+ LE H+IP S GG D DN L +CH Sbjct 202 PAEKVYLLKKQKGRCTYCG----LHFQDGD-LLETDHIIPKSKGGKDNRDNKQLLHRHCH 256 >gb|AAU87367.1| MnlI restriction endonuclease [Moraxella nonliquefaciens] Length=386 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/55 (49%), Positives = 31/55 (56%), Gaps = 9/55 (16%) Query 224 YLEVHHVIPLSSGGA-DTTDNCVALCPNCHRELHYSKN------AKELIEMLYVN 271 YLEVHHVI +S D DN V +CP CHR L SKN KELI + +N Sbjct 308 YLEVHHVISFASDRTLDQIDNLVKVCPTCHRAL--SKNRADEQYQKELISEILIN 360 >gb|EBJ96700.1| hypothetical protein GOS_8810499 [marine metagenome] Length=178 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 31/104 (29%), Positives = 45/104 (43%), Gaps = 9/104 (8%) Query 151 PTDDES--LLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208 P D ES LL S ++ ++ G R+ + R K ++ Q C Sbjct 73 PVDKESADLLAPLASFGAVQSCTETIGERRMLGSGRAGNKRCVSETKKKFVASQQGWTCG 132 Query 209 NCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +CGK P + EV H + L GG++ DN VALC +CH Sbjct 133 DCGKQLP-------AWFEVDHRVRLDRGGSNHVDNLVALCRDCH 169 >ref|ZP_08334725.1| hypothetical protein HMPREF0987_01028 [Lachnospiraceae bacterium 9_1_43BFAA] gb|EGG86070.1| hypothetical protein HMPREF0987_01028 [Lachnospiraceae bacterium 9_1_43BFAA] Length=160 Score = 46.6 bits (109), Expect = 0.004, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 8/93 (8%) Query 186 QKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGN-PYLEVHHVIPLS-----SGGAD 239 + ++ R +++ + + CE ++ F N PY+E HH +P+S S D Sbjct 42 KTIWKRSGVLRTQAFELANYKCELNREHETFIAESTNKPYMEGHHALPMSLQDQFSVSLD 101 Query 240 TTDNCVALCPNCHRELHY--SKNAKELIEMLYV 270 N V LCP CHR++HY K +++ +YV Sbjct 102 VYSNIVCLCPLCHRKIHYGMENEKKIMLDSIYV 134 >ref|ZP_05615751.1| putative HNH endonuclease domain protein [Faecalibacterium prausnitzii A2-165] gb|EEU95887.1| putative HNH endonuclease domain protein [Faecalibacterium prausnitzii A2-165] Length=367 Score = 46.6 bits (109), Expect = 0.005, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 6/71 (8%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 ER + P + ++ KGIC CGK+ F + + ++ H+ P S GG T + Sbjct 298 ERHLNIRAFSPEMARAAYERQKGICPKCGKH--FEIEE----MQADHITPWSKGGKTTAE 351 Query 243 NCVALCPNCHR 253 NC LC +C+R Sbjct 352 NCQMLCADCNR 362 >ref|ZP_07388892.1| HNH endonuclease [Paenibacillus curdlanolyticus YK9] gb|EFM09521.1| HNH endonuclease [Paenibacillus curdlanolyticus YK9] Length=482 Score = 46.6 bits (109), Expect = 0.005, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 3/87 (3%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLE 226 K + +P G+ PV V+ VR + ++ C+ CG+ L G + E Sbjct 270 KNLVVKPIGTLLPVRVKNTVSRVVRSSSLVRYLRDLYSDACQICGQRID--LGPGGTFSE 327 Query 227 VHHVIPLSSG-GADTTDNCVALCPNCH 252 VHH+ PL GAD +N + +CPN H Sbjct 328 VHHIQPLGKHRGADVIENMIVVCPNHH 354 >ref|YP_004464780.1| HNH endonuclease [Mahella australiensis 50-1 BON] gb|AEE97958.1| HNH endonuclease [Mahella australiensis 50-1 BON] Length=125 Score = 46.6 bits (109), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/85 (35%), Positives = 42/85 (49%), Gaps = 16/85 (18%) Query 181 EVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHV 230 E +R ++ Y RDP V+ W + + I CE C K P EVHH+ Sbjct 30 EAKRYER-YDRDPAVRKRYNRTWKRIRDRYIAEHPLCERCEKQGRI-----TPAEEVHHI 83 Query 231 IPLSSGGADTTDNCVALCPNCHREL 255 PLS GG + T N ++LC +CH E+ Sbjct 84 KPLSCGGTNETSNLMSLCTSCHSEI 108 >gb|ECE17206.1| hypothetical protein GOS_4015603 [marine metagenome] Length=128 Score = 46.6 bits (109), Expect = 0.005, Method: Compositional matrix adjust. Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query 207 CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTD--NCVALCPNCHRELHYSK---N 260 CE CG + A Y N G+ + E HH +PLS G T + LC NCHR +H K + Sbjct 53 CEACGFDFALVYGNRGDGFAECHHKVPLSESGTVKTRLVDLAILCANCHRMIHVRKPMLS 112 Query 261 AKELIEMLYVNIN 273 +EL +++ N N Sbjct 113 IEELRDLIMGNSN 125 >ref|ZP_08564108.1| recombinase [Lactobacillus ruminis SPM0211] gb|EGM50211.1| recombinase [Lactobacillus ruminis SPM0211] Length=285 Score = 46.2 bits (108), Expect = 0.005, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 11/145 (7%) Query 135 SFWASIIRGELSELSQ-PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193 +F+++ I G L L Q + + S+ K L + + PV+ LQ Y R+P Sbjct 120 NFYSATINGYLDYLDQLKIVNAGEIKESPSERYKIKLLKKPVRKSPVQTTILQ--YPRNP 177 Query 194 MVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSG-----GADTTDNCVAL 247 +S C + F ND ++E HH+IP+ D DN + L Sbjct 178 HEMLAAKHRSGWKCCYDSSHETFISENDHKNFVEGHHLIPMQHQCDFEYTIDFADNIIPL 237 Query 248 CPNCHRELHYS--KNAKELIEMLYV 270 CP CHR +H++ ++ ++E Y Sbjct 238 CPTCHRRIHFAIKQDRNRMLEKFYF 262 >ref|ZP_08079957.1| recombinase [Lactobacillus ruminis ATCC 25644] gb|EFZ35510.1| recombinase [Lactobacillus ruminis ATCC 25644] Length=270 Score = 46.2 bits (108), Expect = 0.005, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 63/145 (43%), Gaps = 11/145 (7%) Query 135 SFWASIIRGELSELSQ-PTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDP 193 +F+++ I G L L Q + + S+ K L + + PV+ LQ Y R+P Sbjct 105 NFYSATINGYLDYLDQLKIVNAGEIKESPSERYKIKLLKKPVRKSPVQTTILQ--YPRNP 162 Query 194 MVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSG-----GADTTDNCVAL 247 +S C + F ND ++E HH+IP+ D DN + L Sbjct 163 HEMLAAKHRSGWKCCYDSSHETFISENDHKNFVEGHHLIPMQHQCDFEYTIDFADNIIPL 222 Query 248 CPNCHRELHYS--KNAKELIEMLYV 270 CP CHR +H++ ++ ++E Y Sbjct 223 CPTCHRRIHFAIKQDRNRMLEKFYF 247 >ref|YP_305634.1| hypothetical protein Mbar_A2123 [Methanosarcina barkeri str. Fusaro] gb|AAZ71054.1| hypothetical protein Mbar_A2123 [Methanosarcina barkeri str. Fusaro] Length=268 Score = 46.2 bits (108), Expect = 0.005, Method: Compositional matrix adjust. Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD--NCVALCPNCHRELHYSKNAKEL 264 C CG F +G Y EVHH+I L+ +T N + +CP CHR+LHY+ E Sbjct 193 CMICGYPG-FLKKNGEKYAEVHHMIELNQKAPETLQSWNLLVVCPLCHRKLHYADVKSEF 251 Query 265 IE 266 ++ Sbjct 252 LD 253 >ref|ZP_00514900.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM51735.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=536 Score = 46.2 bits (108), Expect = 0.005, Method: Compositional matrix adjust. Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 +Y PM + +L++ KGIC C ++ F +D +EV H+IP S GG D DN AL Sbjct 446 IYTGTPMRVSKLLKKQKGICPICKQH--FTPDD---LIEVDHIIPKSKGGKDRYDNLQAL 500 Query 248 CPNCH 252 +CH Sbjct 501 HRHCH 505 >ref|YP_871419.1| HNH endonuclease [Shewanella sp. ANA-3] gb|ABK50013.1| HNH endonuclease [Shewanella sp. ANA-3] Length=224 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 9/99 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EGS K V V + Y RD + + C+ CG N + Y G ++EVHH+ P Sbjct 123 EGSVKRVLVNK----YERDAKARKACIAHHGCQCKVCGFNFSETYGLHGEGFIEVHHITP 178 Query 233 LS----SGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267 LS S D ++ + +C NCH LH K + E+ Sbjct 179 LSTISKSYQVDPINDLIPVCSNCHSMLHRGKEPLSIDEL 217 >gb|ADW79676.1| putative HNH endonuclease [Salmonella enterica subsp. enterica serovar Kentucky] Length=304 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 10/90 (11%) Query 189 YVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNP--YLEVHHVIPLSS-----GGADT 240 Y R V L ++ CE NC + P + +P Y E HH++P+S D Sbjct 190 YPRSKSVSKNALNKADYKCEINC--DHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 247 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYV 270 +N ++LC NCH+++H K ++++ +Y Sbjct 248 EENIISLCCNCHKQIHLGKGFEDMLRKIYA 277 >ref|ZP_00515193.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM52028.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=165 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 5/65 (7%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 +Y PM + +L++ KGIC C ++ F +D +EV H+IP S GG D DN AL Sbjct 75 IYTGTPMRVSKLLKKQKGICPICKQH--FTPDD---LIEVDHIIPKSKGGKDRYDNLQAL 129 Query 248 CPNCH 252 +CH Sbjct 130 HRHCH 134 >ref|NP_943492.1| HNH endonuclease [Klebsiella pneumoniae] gb|AAR07842.1| Hnh [Klebsiella pneumoniae] Length=304 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 10/90 (11%) Query 189 YVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNP--YLEVHHVIPLSS-----GGADT 240 Y R V L ++ CE NC + P + +P Y E HH++P+S D Sbjct 190 YPRSKSVSKNALNKADYKCEINC--DHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 247 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYV 270 +N ++LC NCH+++H K ++++ +Y Sbjct 248 EENIISLCCNCHKQIHLGKGFEDMLRKIYA 277 >ref|ZP_04172360.1| hypothetical protein bmyco0001_56780 [Bacillus mycoides DSM 2048] gb|EEL95939.1| hypothetical protein bmyco0001_56780 [Bacillus mycoides DSM 2048] Length=140 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 10/76 (13%) Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADT 240 E E+L++ + R+ + W + +CE C +L HH IPL +GG + Sbjct 3 EYEQLRQKF-RNISKQYWKQTKKPKMCEKCFSKTDVHL---------HHKIPLKTGGTND 52 Query 241 TDNCVALCPNCHRELH 256 DN + LC CH E H Sbjct 53 YDNLIPLCEECHWEFH 68 >ref|YP_002886492.1| HNH endonuclease [Exiguobacterium sp. AT1b] gb|ACQ71047.1| HNH endonuclease [Exiguobacterium sp. AT1b] Length=346 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 38/134 (28%), Positives = 58/134 (43%), Gaps = 12/134 (8%) Query 141 IRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWIL 200 + GEL + D+ L + + ++L EG RK V V Y R+P+ + + Sbjct 204 LMGELKDYITSFFDKDLTAEYYADEVAESLE--EGKRKVVTV----NTYERNPLARKRCM 257 Query 201 QQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHREL 255 + C+ C N Y G ++ VHH+ PL G D + +CPNCH L Sbjct 258 EYYGVSCQVCQINFEKIYGEVGRDFIHVHHIKPLHEIGQNYVVDPITDLRPVCPNCHAML 317 Query 256 HYSKNAKEL-IEML 268 H + + L IE L Sbjct 318 HRKEGGEYLTIEQL 331 >ref|ZP_03065878.1| Hnh [Shigella dysenteriae 1012] gb|EDX34285.1| Hnh [Shigella dysenteriae 1012] Length=302 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 10/90 (11%) Query 189 YVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNP--YLEVHHVIPLSS-----GGADT 240 Y R V L ++ CE NC + P + +P Y E HH++P+S D Sbjct 188 YPRSKSVSKNALNKADYKCEINC--DHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 245 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYV 270 +N ++LC NCH+++H K ++++ +Y Sbjct 246 EENIISLCCNCHKQIHLGKGFEDMLRKIYA 275 >ref|NP_681791.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC08553.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] Length=317 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 5/58 (8%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 + ++ GIC CG + + E+HH++P GG D DN V + NCH+++H Sbjct 250 LWKKQGGICPVCGGEI-----EQDMLTEIHHILPKHKGGTDDLDNLVLIHTNCHKQVH 302 >ref|YP_001687961.1| HNH endonuclease [Klebsiella pneumoniae NTUH-K2044] dbj|BAH66060.1| endonuclease [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Length=304 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 10/90 (11%) Query 189 YVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNP--YLEVHHVIPLSS-----GGADT 240 Y R V L ++ CE NC + P + +P Y E HH++P+S D Sbjct 190 YPRSKSVSKNALNKADYKCEINC--DHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 247 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYV 270 +N ++LC NCH+++H K ++++ +Y Sbjct 248 EENIISLCCNCHKQIHLGKGFEDMLRKIYA 277 >ref|ZP_01069662.1| MnlI restriction endonuclease [Campylobacter jejuni subsp. jejuni 260.94] gb|EAQ59041.1| MnlI restriction endonuclease [Campylobacter jejuni subsp. jejuni 260.94] Length=259 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 6/57 (10%) Query 205 GICENCGK-----NAPFYLNDGNPYLEVHHVIPLS-SGGADTTDNCVALCPNCHREL 255 +C C K + F + +G YLE+HH I + S D DN V LCP CHR L Sbjct 154 DLCAACNKTYNIDDRSFKMKNGFYYLELHHNIAFAYSNECDELDNLVKLCPTCHRAL 210 >gb|EBY67131.1| hypothetical protein GOS_4901265 [marine metagenome] Length=284 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 33/54 (61%), Gaps = 6/54 (11%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L++SKG CE CG + + LEV H+IP ++GG+D N ALC +C+ Sbjct 143 VLKRSKGRCEVCG------ITNDKKALEVDHIIPRANGGSDELHNLQALCYSCN 190 >ref|ZP_06964988.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] ref|ZP_06973380.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] gb|EFH81447.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] gb|EFH88099.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] Length=598 Score = 46.2 bits (108), Expect = 0.006, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA +LQ+ +G C CG Y D + +E+ H+ P S GG + N AL +CH E Sbjct 505 VKAKLLQKQEGKCRWCG----LYFKDED-LIEIDHITPKSEGGGEELSNKFALHRHCHDE 559 Query 255 LHYSK 259 H K Sbjct 560 RHSKK 564 >ref|ZP_06966392.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] gb|EFH89503.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] Length=598 Score = 46.2 bits (108), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA +LQ+ +G C CG Y D + +E+ H+ P S GG + N AL +CH E Sbjct 505 VKAKLLQKQEGKCRWCG----LYFKDED-LIEIDHITPKSEGGGEELSNKFALHRHCHDE 559 Query 255 LHYSK 259 H K Sbjct 560 RHSKK 564 >ref|ZP_06964959.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] gb|EFH88070.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] Length=598 Score = 46.2 bits (108), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA +LQ+ +G C CG Y D + +E+ H+ P S GG + N AL +CH E Sbjct 505 VKAKLLQKQEGKCRWCG----LYFKDED-LIEIDHITPKSEGGGEELSNKFALHRHCHDE 559 Query 255 LHYSK 259 H K Sbjct 560 RHSKK 564 >ref|NP_681409.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC08171.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] Length=562 Score = 46.2 bits (108), Expect = 0.007, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 5/58 (8%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 + ++ GIC CG + + E+HH++P GG D DN V + NCH+++H Sbjct 495 LWKKQGGICPVCGGEI-----EQDMLTEIHHILPKHKGGTDDLDNLVLIHTNCHKQVH 547 >ref|ZP_06968421.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] gb|EFH85961.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] Length=598 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA +LQ+ +G C CG Y D + +E+ H+ P S GG + N AL +CH E Sbjct 505 VKAKLLQKQEGKCRWCG----LYFKDED-LIEIDHITPKSEGGGEELSNKFALHRHCHDE 559 Query 255 LHYSK 259 H K Sbjct 560 RHSKK 564 >ref|ZP_06966276.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] ref|ZP_06968314.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] ref|ZP_06968412.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] 11 more sequence titles Length=598 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA +LQ+ +G C CG Y D + +E+ H+ P S GG + N AL +CH E Sbjct 505 VKAKLLQKQEGKCRWCG----LYFKDED-LIEIDHITPKSEGGGEELSNKFALHRHCHDE 559 Query 255 LHYSK 259 H K Sbjct 560 RHSKK 564 >gb|ECN95299.1| hypothetical protein GOS_3902663 [marine metagenome] Length=74 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 7/58 (12%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 IL++ + CE CG D P L +HH++ GG D+ N + LC NCH E+H Sbjct 1 ILEERRNCCEVCGY-------DKTPVLTIHHIVERYLGGDDSNANLLVLCRNCHGEVH 51 >ref|ZP_06965526.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] gb|EFH88637.1| RNA-directed DNA polymerase (Reverse transcriptase) [Ktedonobacter racemifer DSM 44963] Length=598 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 34/65 (52%), Gaps = 5/65 (7%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 VKA +LQ+ +G C CG Y D + +E+ H+ P S GG + N AL +CH E Sbjct 505 VKAKLLQKQEGKCRWCG----LYFKDED-LIEIDHITPKSEGGGEELSNKFALHRHCHDE 559 Query 255 LHYSK 259 H K Sbjct 560 RHSKK 564 >ref|ZP_08431987.1| restriction endonuclease [Lyngbya majuscula 3L] gb|EGJ28995.1| restriction endonuclease [Lyngbya majuscula 3L] Length=156 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/72 (37%), Positives = 42/72 (58%), Gaps = 6/72 (8%) Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHREL 255 KA +L++ KG C +CG D + +E+HH++P ++GG + +N L +CH Sbjct 87 KAKLLKRQKGKCSHCG----LTFRDRDE-MEMHHILPRANGGTNKDENLELLHLHCHDAK 141 Query 256 HYSK-NAKELIE 266 H +K NAKEL E Sbjct 142 HGTKVNAKELDE 153 >ref|YP_003602536.1| HNH endonuclease [Enterobacter cloacae subsp. cloacae ATCC 13047] gb|ADF64728.1| HNH endonuclease [Enterobacter cloacae subsp. cloacae ATCC 13047] Length=302 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 5/59 (8%) Query 224 YLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 Y E HH++P+S A D +N ++LC NCH+++H + +++++ +Y RL K Sbjct 224 YTEPHHIVPMSRQDAFDTSLDVEENIISLCCNCHKQIHLGQGYEDMLKEIYTARKRLLK 282 >ref|ZP_04558947.1| HNH endonuclease [Citrobacter sp. 30_2] gb|EEH95862.1| HNH endonuclease [Citrobacter sp. 30_2] Length=304 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 35/59 (59%), Gaps = 5/59 (8%) Query 224 YLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 Y E HH++P+S A D +N ++LC NCH+++H + +++++ +Y RL K Sbjct 226 YTEPHHIVPMSRQDAFDTSLDVEENIISLCCNCHKQIHLGQGYEDMLKEIYTARKRLLK 284 >ref|NP_618379.1| HNH endonuclease [Methanosarcina acetivorans C2A] gb|AAM06859.1| Hnh endonuclease [Methanosarcina acetivorans C2A] Length=279 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 13/110 (11%) Query 171 SQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHH 229 S PEG + R Y R+ + + +C+ CG + Y G Y+EVHH Sbjct 172 STPEGKKILCYTTR----YERNAQNRRNAIAIHGTVCQGCGFDFEKTYGEIGRDYIEVHH 227 Query 230 VIPL----SSGGADTTDNCVALCPNCHRELHYSKNA----KELIEMLYVN 271 V PL S + + + +C NCHR +H K++ KEL E+L N Sbjct 228 VKPLCEEEGSVPINAETDLICVCANCHRMIHRRKDSVLSLKELQELLLAN 277 >ref|ZP_08603840.1| hypothetical protein HMPREF0993_03217 [Lachnospiraceae bacterium 5_1_57FAA] gb|EGN33309.1| hypothetical protein HMPREF0993_03217 [Lachnospiraceae bacterium 5_1_57FAA] Length=263 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 29/97 (29%), Positives = 46/97 (47%), Gaps = 7/97 (7%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLSSGG------ADT 240 +Y R V + L ++ +CE ++ F N Y E HH++PL + D Sbjct 151 LYQRSKEVSSNALMKAGFLCEVDAEHPVFIRKHSNENYTEPHHLVPLFAQNDFPDINLDR 210 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYVNINRLQK 277 N V+LC +CH LHY + E++ LY++ L K Sbjct 211 EQNVVSLCSHCHNLLHYGSDIDEVLYKLYMSRKELLK 247 >ref|ZP_04625948.1| HNH nuclease [Yersinia kristensenii ATCC 33638] gb|EEP89560.1| HNH nuclease [Yersinia kristensenii ATCC 33638] Length=330 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 2/66 (3%) Query 192 DPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 DP V+ +L++ C NCG ND LE+HH+ GG +T +N + LC Sbjct 247 DP-VRVKVLERDHHSCRNCGWQYQLKKPNDPRSLLELHHIEHHVDGGENTVENLLTLCNV 305 Query 251 CHRELH 256 CH E+H Sbjct 306 CHDEVH 311 >gb|ECQ08039.1| hypothetical protein GOS_3561047 [marine metagenome] Length=190 Score = 45.8 bits (107), Expect = 0.007, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 7/59 (11%) Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 K ++ Q K +C C N EV H + L +GG + +N ALCPNCHRE Sbjct 130 KKYVASQQKWMCGKCN-------NMLGATFEVDHKVELQNGGTNHVNNLWALCPNCHRE 181 >gb|EBK97491.1| hypothetical protein GOS_8644481 [marine metagenome] Length=343 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 10/105 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCG-KNAPFYLNDGNPYLEVHHVIP 232 EG K + V Y RD + ++ C+ CG + + FY + G ++ VHH P Sbjct 243 EGKAKQIYV----NTYERDRGARKKCIEHYSCKCQVCGFEFSDFYGDMGEGFIHVHHRTP 298 Query 233 LSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEMLYVNIN 273 L+S G D + + +CPNCH LH ++ +E L IN Sbjct 299 LASIGETYKVDPVKDLIPVCPNCHAMLH-KGSSPPTVEELKQRIN 342 >ref|NP_680822.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC07584.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] Length=564 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 PE + + ++L+K + ++ + ++ GIC CG + + ++HH++P Sbjct 471 PEWAEYFEKRKKLKKAPAQYRRIRRELWKKQGGICPVCGGEI-----EQDMLTDIHHILP 525 Query 233 LSSGGADTTDNCVALCPNCHRELH 256 GG+D DN V + NCH+++H Sbjct 526 KHKGGSDDLDNLVLIHANCHKQVH 549 >ref|NP_681951.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC08713.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] Length=564 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 PE + + ++L+K + ++ + ++ GIC CG + + ++HH++P Sbjct 471 PEWAEYFEKRKKLKKAPAQYRRIRRELWKKQGGICPVCGGEI-----EQDMLTDIHHILP 525 Query 233 LSSGGADTTDNCVALCPNCHRELH 256 GG+D DN V + NCH+++H Sbjct 526 KHKGGSDDLDNLVLIHANCHKQVH 549 >ref|ZP_00517210.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM49703.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=471 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 12/93 (12%) Query 165 LIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +++ TL +PE S P + + + Y P A +L++ KGIC C + F Sbjct 355 ILRHTLVKPEAS--PYDGNWTYWSKRRGTYSGTPTRVAKLLKKQKGICPQCKQY--FTPE 410 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 D +EV H+IP S GG DT +N AL +CH Sbjct 411 D---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 440 >ref|YP_003672198.1| HNH endonuclease [Geobacillus sp. C56-T3] gb|ADI27621.1| HNH endonuclease [Geobacillus sp. C56-T3] Length=253 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 32/88 (36%), Positives = 42/88 (47%), Gaps = 9/88 (10%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EG +K V V R Y R+ + LQ+ C C + Y G ++EVHH+IP Sbjct 144 EGGKKLVAVNR----YERNARARRLCLQKYGYRCVVCQFDFEEVYGEIGKGFIEVHHLIP 199 Query 233 LSSGGADTT----DNCVALCPNCHRELH 256 LS G T D+ +CPNCH LH Sbjct 200 LSEIGEQYTVNPFDDLRPVCPNCHAMLH 227 >ref|NP_681099.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] ref|NP_681312.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC07861.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] dbj|BAC08074.1| reverse transcriptase [Thermosynechococcus elongatus BP-1] Length=564 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 PE + + ++L+K + ++ + ++ GIC CG + + ++HH++P Sbjct 471 PEWAEYFEKRKKLKKAPAQYRRIRRELWKKQGGICPVCGGEI-----EQDMLTDIHHILP 525 Query 233 LSSGGADTTDNCVALCPNCHRELH 256 GG+D DN V + NCH+++H Sbjct 526 KHKGGSDDLDNLVLIHANCHKQVH 549 >ref|ZP_00513655.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM52858.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=164 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 12/106 (11%) Query 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGI 206 T D L + +++ + L +PE S P + + + Y P A +L++ KGI Sbjct 35 TRDYVLYHHAETEIKRHQLVKPEAS--PYDGNWTYWSKRRGTYTGTPTRVAKLLKKQKGI 92 Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 C C ++ F D +EV H+IP S GG DT N AL +CH Sbjct 93 CPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYSNLQALHRHCH 133 >ref|YP_001133838.1| HNH endonuclease [Mycobacterium gilvum PYR-GCK] ref|YP_004076496.1| restriction endonuclease [Mycobacterium sp. Spyr1] gb|ABP45050.1| HNH endonuclease [Mycobacterium gilvum PYR-GCK] gb|ADT98661.1| restriction endonuclease [Mycobacterium sp. Spyr1] Length=220 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 26/66 (39%), Positives = 33/66 (50%), Gaps = 11/66 (16%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R PM +A ++ + + C CG A V HVIP S GGA T +NCVA C Sbjct 119 ARIPMTRAALMHRDRFRCAYCGSKAD----------TVDHVIPRSRGGAHTWENCVAACS 168 Query 250 NC-HRE 254 C HR+ Sbjct 169 ACNHRK 174 >ref|YP_003887722.1| RNA-directed DNA polymerase [Cyanothece sp. PCC 7822] gb|ADN14447.1| RNA-directed DNA polymerase [Cyanothece sp. PCC 7822] Length=606 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 5/56 (8%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 +L++ KG C +CG + ++G+ LEV H+IP SSGG D +N L +CH E Sbjct 527 LLKEQKGKCNHCG----LFFSEGDK-LEVDHIIPKSSGGRDEYENLQLLHRHCHDE 577 >ref|ZP_00518382.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM48545.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=165 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 32/93 (34%), Positives = 47/93 (50%), Gaps = 12/93 (12%) Query 165 LIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +++ TL +PE S P + + + Y P A +L++ KGIC C + F Sbjct 49 ILRHTLVKPEAS--PYDGNWTYWSKRRGTYSGTPTRVAKLLKKQKGICPQCKQY--FTPE 104 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 D +EV H+IP S GG DT +N AL +CH Sbjct 105 D---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 134 >ref|ZP_04556006.1| predicted protein [Bacteroides sp. D4] gb|EEO46289.1| predicted protein [Bacteroides dorei 5_1_36/D4] Length=274 Score = 45.8 bits (107), Expect = 0.008, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 10/109 (9%) Query 158 LNMRVSKLIKKTLSQPEGSRKPVEVE-RLQKV----YVRDPMVKAWILQQSKGICENCGK 212 + S L +S+ E +K V+ E +Q++ Y R+P+ + L + C CG Sbjct 148 FELIFSLLTITDISEEEFLQKAVQTEGTIQEIKSIRYERNPINRKLCLYKKGYTCAVCGM 207 Query 213 N-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELH 256 N Y + G ++EVHH P+S G D + V LC NCH H Sbjct 208 NFQDVYGDIGKGFIEVHHTTPVSKMGEGYNLDIERDLVPLCSNCHSMTH 256 >ref|ZP_07323074.1| HNH endonuclease domain protein [Prevotella disiens FB035-09AN] gb|EFL46346.1| HNH endonuclease domain protein [Prevotella disiens FB035-09AN] Length=367 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 + ++ KGIC CGK+ F + + +E H+IP GG DNC LC C+R Sbjct 314 VYEEQKGICPICGKH--FEIEE----MEADHIIPWHKGGKTEKDNCQMLCMKCNR 362 >gb|EDJ12277.1| hypothetical protein GOS_1750925 [marine metagenome] Length=107 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 10/89 (11%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND--GNPYLEVHHVI 231 EG+ + + V R Y RDP + L C C + D G + VHHVI Sbjct 6 EGAVRTITVNR----YERDPKARQVCLAHHGYTCYACDADLTKTYGDELGRRAIHVHHVI 61 Query 232 PLSSGGA----DTTDNCVALCPNCHRELH 256 P+++ G D ++ V LCPNCH +H Sbjct 62 PMATRGKKYQLDPINDLVPLCPNCHNVIH 90 >gb|ECS44854.1| hypothetical protein GOS_4663789 [marine metagenome] Length=101 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 8/70 (11%) Query 196 KAWILQQSKGI-CENCGKNAPF---YLNDGNPYLEVHHVIPLSSGGADTTD--NCVALCP 249 K ++L + + CE C N F Y G Y+E HH +PLSSG TT + +C Sbjct 20 KQYVLNATGKLECEVC--NFAFKEKYGQHGEDYIECHHKLPLSSGAMKTTKLADLALVCA 77 Query 250 NCHRELHYSK 259 NCHR LH K Sbjct 78 NCHRMLHRGK 87 >ref|ZP_01903770.1| HNH nuclease [Roseobacter sp. AzwK-3b] gb|EDM70802.1| HNH nuclease [Roseobacter sp. AzwK-3b] Length=114 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 7/59 (11%) Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 +AW ++++G CE CG LN G+ E H IP GG ++ +NCV LC CHR+ Sbjct 13 QAW--ERARGKCEECG----VKLNVGD-RREFDHRIPCGLGGDNSLENCVVLCAACHRD 64 >ref|ZP_04658302.1| conserved hypothetical protein [Selenomonas flueggei ATCC 43531] gb|EEQ49126.1| conserved hypothetical protein [Selenomonas flueggei ATCC 43531] Length=363 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 6/53 (11%) Query 201 QQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 Q+ KGIC CGK F + + ++ H+ P S GG T +NC LC C+R Sbjct 312 QRQKGICPKCGKQ--FQIEE----MQADHITPWSKGGKTTPENCQMLCAPCNR 358 >ref|YP_180821.1| HNH endonuclease domain-containing protein [Dehalococcoides ethenogenes 195] gb|AAW39066.1| HNH endonuclease domain protein [Dehalococcoides ethenogenes 195] Length=118 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 5/47 (10%) Query 206 ICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +CE C K P EVHH++PLS GG++ N +ALC +CH Sbjct 65 LCEECDKQGKL-----TPAEEVHHILPLSKGGSNEKSNLMALCKSCH 106 >ref|ZP_00515251.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM51568.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=379 Score = 45.4 bits (106), Expect = 0.009, Method: Compositional matrix adjust. Identities = 31/95 (32%), Positives = 49/95 (51%), Gaps = 12/95 (12%) Query 163 SKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFY 217 +++ + TL +PE S P + + + Y P A +L++ KGIC C ++ F Sbjct 261 TEIKRHTLVKPEAS--PYDGNWTYWSKRRGTYTGTPTRVAKLLKKQKGICPQCKQH--FT 316 Query 218 LNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +D +EV H+IP S GG D +N AL +CH Sbjct 317 PDD---LIEVDHIIPKSKGGKDEFNNLQALHRHCH 348 >ref|ZP_06080041.1| HNH endonuclease [Vibrio sp. RC586] ref|ZP_06942423.1| conserved hypothetical protein [Vibrio cholerae RC385] gb|EEY99122.1| HNH endonuclease [Vibrio sp. RC586] gb|EFH74976.1| conserved hypothetical protein [Vibrio cholerae RC385] Length=244 Score = 45.4 bits (106), Expect = 0.010, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 9/93 (9%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLND-GNPYLEVHHVIP 232 EG+RK + V Y R+ +A ++ C C N Y D G Y+ VHH + Sbjct 140 EGARKQITV----NAYERNHRARAQCIEHYGNSCYICSFNFFEYFGDLGAGYIHVHHQVD 195 Query 233 LSSGG----ADTTDNCVALCPNCHRELHYSKNA 261 L+ G + ++ +CPNCH LH +K A Sbjct 196 LAHVGEAYIVNPIEDLKPVCPNCHAMLHKTKPA 228 >ref|ZP_07298326.1| HNH endonuclease [Streptomyces hygroscopicus ATCC 53653] gb|EFL26695.1| HNH endonuclease [Streptomyces himastatinicus ATCC 53653] Length=356 Score = 45.4 bits (106), Expect = 0.010, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 4/66 (6%) Query 197 AWILQQSKGI-CENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTT--DNCVALCPNCH 252 A +L+ + + CE CG + Y G Y+E HHV+PL G T + +C NCH Sbjct 248 AAVLKSGRTLACEACGFDFGAVYGERGEGYIECHHVVPLHEAGEGKTKLSDLALICSNCH 307 Query 253 RELHYS 258 R +H S Sbjct 308 RMIHRS 313 >gb|EBO04682.1| hypothetical protein GOS_8146055 [marine metagenome] Length=161 Score = 45.4 bits (106), Expect = 0.010, Method: Compositional matrix adjust. Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 9/101 (8%) Query 170 LSQPEGSRKPVEVERLQKV---YVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYL 225 ++ E P +RL V Y RDP +A L+ C+ CG + Y G + Sbjct 46 VASSEADTPPQYAKRLTMVVNRYERDPQKRAQCLEHYGYDCQICGFSFVKTYGEIGKDFC 105 Query 226 EVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNA 261 VHH+ PL G D + + +C NCH LH K A Sbjct 106 HVHHIEPLGEQGGESKNLDPIKDLIPVCANCHEMLHRKKIA 146 >gb|AAL25965.1| group II intron-associated open reading frame [Azotobacter vinelandii] Length=563 Score = 45.4 bits (106), Expect = 0.011, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 12/84 (14%) Query 183 ERLQKVYVRD-----PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237 ERL+ + R ++ W+ Q + C C + F +HH+I GG Sbjct 477 ERLEYAWRRSDEGKRKTLRLWLGQSKR--CPMCKQLITFETG-----WNIHHIIKRHMGG 529 Query 238 ADTTDNCVALCPNCHRELHYSKNA 261 D DN V L PNCHR+LH + A Sbjct 530 GDELDNLVLLHPNCHRQLHSAAPA 553 >gb|ECD99344.1| hypothetical protein GOS_4710496 [marine metagenome] Length=267 Score = 45.4 bits (106), Expect = 0.011, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query 172 QPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVI 231 +P P+ VE + VR+ + + + +Q C+ CG L +G Y E HV Sbjct 152 RPLPETAPLRVETTTQRIVRNTSMISQLKKQYDNTCQLCGLR--ITLANGAGYSEGAHVK 209 Query 232 PLSSGGADTTDNCVALCPNCH 252 PL+ G D +N + LCPN H Sbjct 210 PLARNGPDIKENVLILCPNHH 230 >ref|YP_002798550.1| RNA-directed DNA polymerase [Azotobacter vinelandii DJ] gb|ACO77575.1| RNA-directed DNA polymerase [Azotobacter vinelandii DJ] Length=515 Score = 45.4 bits (106), Expect = 0.011, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 12/84 (14%) Query 183 ERLQKVYVRD-----PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG 237 ERL+ + R ++ W+ Q + C C + F +HH+I GG Sbjct 429 ERLEYAWRRSDEGKRKTLRLWLGQSKR--CPMCKQLITFETG-----WNIHHIIKRHMGG 481 Query 238 ADTTDNCVALCPNCHRELHYSKNA 261 D DN V L PNCHR+LH + A Sbjct 482 GDELDNLVLLHPNCHRQLHSAAPA 505 >ref|ZP_00517704.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM49204.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=87 Score = 45.1 bits (105), Expect = 0.011, Method: Composition-based stats. Identities = 26/68 (38%), Positives = 37/68 (54%), Gaps = 5/68 (7%) Query 185 LQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNC 244 ++ Y P A +L++ KGIC C ++ F D +EV H+IP S GG DT +N Sbjct 11 IRGTYTGTPTRVAKLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGKDTYNNL 65 Query 245 VALCPNCH 252 AL +CH Sbjct 66 QALHRHCH 73 >ref|YP_846912.1| HNH endonuclease [Syntrophobacter fumaroxidans MPOB] gb|ABK18477.1| HNH endonuclease [Syntrophobacter fumaroxidans MPOB] Length=309 Score = 45.1 bits (105), Expect = 0.011, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 2/63 (3%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNP-YLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 V+ +LQ+ C CG + + N +P +LE HHV P GG +T +N + LC CH Sbjct 246 VRRQVLQRDAHKCLRCGWSHERW-NPSDPRHLEAHHVDPHGRGGENTPENLITLCNICHD 304 Query 254 ELH 256 +H Sbjct 305 AVH 307 >gb|EBG19539.1| hypothetical protein GOS_9474002 [marine metagenome] Length=84 Score = 45.1 bits (105), Expect = 0.011, Method: Composition-based stats. Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 14/79 (17%) Query 188 VYVRDPMVKAWILQQSKGICE----------NCGKNAPFYLN--DGNPYLEVHHVIPLSS 235 V+ D + +AW Q+S G CE C K+ + L+ + + E HH +SS Sbjct 2 VFSEDVIKQAW--QRSGGRCECERTRCGHTVGCNKSLSWNLHGKETSGGWEAHHRTAISS 59 Query 236 GGADTTDNCVALCPNCHRE 254 GG+DT +NC LC CH++ Sbjct 60 GGSDTLENCEILCQECHKK 78 >ref|YP_003049279.1| HNH endonuclease [Methylotenera mobilis JLW8] gb|ACT48752.1| HNH endonuclease [Methylotenera mobilis JLW8] Length=238 Score = 45.1 bits (105), Expect = 0.012, Method: Compositional matrix adjust. Identities = 26/77 (33%), Positives = 39/77 (50%), Gaps = 11/77 (14%) Query 191 RDPMVKAWILQQSKG----ICENCGKNAPFYLNDG---NPYLEVHHVIPLSSGGADTT-- 241 R+P ++ +L + CE CG AP + ++ + E HH+IPLS+ G T Sbjct 145 REPKLRGQLLSSRRVSGNLFCEMCG--APPHTSNAMLQEAHFEAHHIIPLSNTGVRKTRL 202 Query 242 DNCVALCPNCHRELHYS 258 + LC NCHR LH + Sbjct 203 SDLALLCANCHRLLHRA 219 >ref|YP_003387900.1| HNH endonuclease [Spirosoma linguale DSM 74] gb|ADB39101.1| HNH endonuclease [Spirosoma linguale DSM 74] Length=367 Score = 45.1 bits (105), Expect = 0.012, Method: Compositional matrix adjust. Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 9/107 (8%) Query 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPY 224 + T + EG+ K + V R Y RD + + C+ C + Y N G Y Sbjct 238 VPSTKTYVEGAVKQITVNR----YERDQDARTDCINHYGAKCQACEFDFEEIYGNIGKGY 293 Query 225 LEVHHVIPL----SSGGADTTDNCVALCPNCHRELHYSKNAKELIEM 267 + VHH+ P +S D + + +CPNCH LH K ++ ++ Sbjct 294 IHVHHIKPFNEIKTSYRVDPIKDLIPVCPNCHAMLHTGKEVMDIADL 340 >ref|YP_003212816.1| hypothetical protein Ctu_3p00720 [Cronobacter turicensis z3032] emb|CBA34777.1| hypothetical protein Ctu_3p00720 [Cronobacter turicensis z3032] Length=208 Score = 45.1 bits (105), Expect = 0.012, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 5/57 (8%) Query 224 YLEVHHVIPLSSGGA-----DTTDNCVALCPNCHRELHYSKNAKELIEMLYVNINRL 275 Y E HH++P+S A D +N ++LC NCH+++H + +++++ +Y RL Sbjct 130 YTEPHHIVPMSRQDAFDTSLDVEENIISLCCNCHKQIHLGQGYEDMLKEIYTARKRL 186 >ref|YP_004522610.1| HNH endonuclease [Mycobacterium sp. JDM601] gb|AEF35356.1| HNH endonuclease [Mycobacterium sp. JDM601] Length=329 Score = 45.1 bits (105), Expect = 0.012, Method: Compositional matrix adjust. Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 15/115 (13%) Query 145 LSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSK 204 + +L P DDE + +L+++ E +K + +++ R P V Sbjct 208 VEQLLTPIDDEDD-EAKEGRLLQRQHFVRERDKK-LRAKKIADFLTRHPRVH-------- 257 Query 205 GICENCGKN-APFYLNDGNPYLEVHHVIPLSSGGADTTD--NCVALCPNCHRELH 256 CE C + Y G+ Y EVHHV+PL + G T + V LC NCHR +H Sbjct 258 --CEVCTFDFEATYGERGHEYTEVHHVVPLHASGETKTKLADLVLLCANCHRMIH 310 >ref|ZP_07111177.1| RNA-directed DNA polymerase [Oscillatoria sp. PCC 6506] emb|CBN56337.1| RNA-directed DNA polymerase [Oscillatoria sp. PCC 6506] Length=571 Score = 45.1 bits (105), Expect = 0.012, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 9/75 (12%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 Y P A ++++ KG+C +CG Y + +EV H+ P SSGG DT DN L Sbjct 494 YPETPNRVATLIKKQKGVCPHCG----LYFTSTD-IVEVDHIKPTSSGGKDTYDNLQLL- 547 Query 249 PNCHRELHYSKNAKE 263 HR H +K A++ Sbjct 548 ---HRHCHDTKTAQD 559 >ref|ZP_00514944.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM51779.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=596 Score = 45.1 bits (105), Expect = 0.012, Method: Compositional matrix adjust. Identities = 35/120 (29%), Positives = 53/120 (44%), Gaps = 19/120 (15%) Query 136 FWASIIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSR---KPVEVERLQKVYVRD 192 FW I+G + L + + +++ T +PE S + + Y Sbjct 462 FWTFQIKGAV-----------LYHHAETGILRHTWVKPEASLYDGNWTYWSKRRGTYSGT 510 Query 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P A +L++ KGIC C + F D +EV H+IP S GG DT +N AL +CH Sbjct 511 PTRVAKLLKKQKGICPQCKQY--FTPED---LIEVDHIIPKSKGGKDTYNNLQALHRDCH 565 >gb|ECJ49505.1| hypothetical protein GOS_4102383 [marine metagenome] Length=154 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 39/154 (25%), Positives = 65/154 (42%), Gaps = 10/154 (6%) Query 57 SQVVVYLASSSVRKHMHSLDERKIHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIP 116 + VV Y+ + ++K++ E G SP+ +M +S GR+ I Sbjct 10 ASVVAYIEMQKLEARGEKFIKKKVYE-ELSEQFGRSPKAFEYRMQNISYVYSVLGRQWIS 68 Query 117 SGNRTKRILINVPGIYSDSFWASIIRGELSELSQPTDDESLLNMRVSKLIKKT-LSQPEG 175 K + NV I + +I +S P + +VSK K L+ P G Sbjct 69 GLKPMKNVGANVLPIIEE-----LINQHEGSISVPQIE---FEEQVSKFRNKARLTTPSG 120 Query 176 SRKPVEVERLQKVYVRDPMVKAWILQQSKGICEN 209 + P + + + RDP V AW+L+ S G+CE+ Sbjct 121 NITPNKQVKESTFFSRDPKVAAWVLKNSNGVCES 154 >gb|EBO93923.1| hypothetical protein GOS_7994644 [marine metagenome] Length=351 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 48/91 (52%), Gaps = 5/91 (5%) Query 171 SQPEGSRKPVE-VERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVH 228 S EGS+K + ++R ++ + + A+I K CE C + + G +EVH Sbjct 254 SWAEGSKKRISHLKRERQSGLANAKKAAFIAIHGKLYCERCNLDPVEMFGKFGAACIEVH 313 Query 229 HVIPLSS--GGADTT-DNCVALCPNCHRELH 256 H++PLS G ++T D+ LC NCHR +H Sbjct 314 HIVPLSEAEGHSNTRLDDLECLCANCHRVVH 344 >gb|EBB89770.1| hypothetical protein GOS_157721 [marine metagenome] Length=196 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 9/66 (13%) Query 192 DPM---VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 DP+ ++ +L+++KG CE CG +++ L+V H+IP S GG++ N +LC Sbjct 124 DPIPGSIRYEVLKRAKGKCELCG------ISNKEKSLDVDHIIPRSKGGSNDISNLQSLC 177 Query 249 PNCHRE 254 C+R+ Sbjct 178 YTCNRQ 183 >gb|EBS57030.1| hypothetical protein GOS_7416319 [marine metagenome] Length=91 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 24/59 (40%), Positives = 30/59 (50%), Gaps = 7/59 (11%) Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 K ++ + K C CG N + EV H I L +GG + DN ALCPNCHRE Sbjct 31 KKYVASRQKWKCGKCG-------NMLDATYEVDHKIELQNGGTNHVDNLWALCPNCHRE 82 >ref|YP_190191.1| HNH endonuclease [Escherichia coli] gb|AAT37586.2| Hnh endonuclease [Escherichia coli] Length=302 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 10/90 (11%) Query 189 YVRDPMVKAWILQQSKGICE-NCGKNAPFYLNDGNP--YLEVHHVIPLSS-----GGADT 240 Y R V L ++ C+ NC + P + +P Y E HH++P+S D Sbjct 188 YPRSKSVSKNALNKADYKCQINC--DHPTFRRRNSPLNYTEPHHIVPMSKQDYFENSLDV 245 Query 241 TDNCVALCPNCHRELHYSKNAKELIEMLYV 270 +N ++LC NCH+++H K ++++ +Y Sbjct 246 EENIISLCCNCHKQIHLGKGFEDMLRKIYA 275 >ref|YP_001263031.1| HNH endonuclease [Sphingomonas wittichii RW1] gb|ABQ68893.1| HNH endonuclease [Sphingomonas wittichii RW1] Length=426 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 43/85 (50%), Gaps = 9/85 (10%) Query 181 EVERLQKVYVR----DPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSG 236 E ++QK +V + KA+ +C+ C + +++HH++PLSSG Sbjct 304 EGNKVQKTHVTIERNSGLRKAFFAANPTTVCDVCNLDTARSYPWTERVMDLHHLLPLSSG 363 Query 237 ----GADTT-DNCVALCPNCHRELH 256 G TT D+ V LCP+CHR +H Sbjct 364 TRVIGRGTTFDDLVPLCPSCHRAVH 388 >ref|YP_003406404.1| HNH endonuclease [Haloterrigena turkmenica DSM 5511] gb|ADB63731.1| HNH endonuclease [Haloterrigena turkmenica DSM 5511] Length=221 Score = 45.1 bits (105), Expect = 0.013, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 11/83 (13%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233 G+R P R + VY D C++CG+ + + + L HH++PL Sbjct 19 SGNRPPDWEARRKTVYRHD-----------NWTCQSCGRQSGPHAGNEGVRLHAHHIVPL 67 Query 234 SSGGADTTDNCVALCPNCHRELH 256 S GG++ N LC CH+ H Sbjct 68 SEGGSNRLSNLETLCEPCHQNQH 90 >ref|ZP_04151047.1| Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 [Bacillus pseudomycoides DSM 12442] gb|EEM17226.1| Paclitaxel/taxanoid biosynthesis susceptibility protein TS1 [Bacillus pseudomycoides DSM 12442] Length=374 Score = 45.1 bits (105), Expect = 0.014, Method: Compositional matrix adjust. Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 14/88 (15%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 + ++ + C+ C K L HH+I SGG+D DN V + CH++ Sbjct 141 TRYYVFTRDHYTCQICKKKGGI--------LHTHHIIERCSGGSDMADNLVTVHEECHQK 192 Query 255 LHYS------KNAKELIEMLYVNINRLQ 276 H K K+ E ++NI RLQ Sbjct 193 FHQGTIKHIFKKPKQYKETAFMNILRLQ 220 >ref|YP_002507119.1| HNH endonuclease [Clostridium cellulolyticum H10] gb|ACL77139.1| HNH endonuclease [Clostridium cellulolyticum H10] Length=119 Score = 45.1 bits (105), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 37/82 (45%), Gaps = 16/82 (19%) Query 181 EVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHV 230 E R +K Y RDP + AW + + I CE C + P EVHH+ Sbjct 30 EAARYEK-YQRDPATRKRYGRAWKRIRDRYIAAHPLCEECKRQEKL-----TPAAEVHHI 83 Query 231 IPLSSGGADTTDNCVALCPNCH 252 +PLS GG N +ALC CH Sbjct 84 LPLSRGGTHDRSNLMALCTPCH 105 >ref|YP_736616.1| RNA-directed DNA polymerase [Shewanella sp. MR-7] gb|ABI41559.1| RNA-directed DNA polymerase [Shewanella sp. MR-7] Length=549 Score = 45.1 bits (105), Expect = 0.014, Method: Compositional matrix adjust. Identities = 17/32 (53%), Positives = 22/32 (68%), Gaps = 0/32 (0%) Query 227 VHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 +HH++ GG+D DN V L PNCHR+LH S Sbjct 518 IHHIVERVRGGSDEMDNLVLLHPNCHRQLHSS 549 >ref|ZP_04611051.1| hypothetical protein yrohd0001_28640 [Yersinia rohdei ATCC 43380] gb|EEQ04414.1| hypothetical protein yrohd0001_28640 [Yersinia rohdei ATCC 43380] Length=206 Score = 44.7 bits (104), Expect = 0.015, Method: Compositional matrix adjust. Identities = 49/177 (27%), Positives = 73/177 (41%), Gaps = 35/177 (19%) Query 111 GRKEIPSGNRTKRILINVPG-IYSDSF----------WASIIRGELSELSQPTDDESLLN 159 R I S R++ + G Y+DSF + S + ELS P + +LN Sbjct 41 NRTTISSNEEITRLISKMSGGYYADSFVSNCSTAMRRYLSFVNSELSYFHYP---DEILN 97 Query 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYL 218 S+ I EG++K + V Y RD + ++ C C N Y Sbjct 98 H--SEYI-------EGAKKQIIVNS----YERDRDARNKAIEIHGLNCSVCDMNFEDVYG 144 Query 219 NDGNPYLEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHYSKN---AKELIEML 268 G ++ VHH+ PL D D+ + +CPNCH LH KN KEL +++ Sbjct 145 EIGVGFIHVHHLKPLHEINKEYHVDPEDDLITVCPNCHAMLHRLKNRPSKKELKDLI 201 >ref|YP_001662871.1| HNH endonuclease [Thermoanaerobacter sp. X514] ref|ZP_07132617.1| HNH endonuclease [Thermoanaerobacter sp. X561] ref|YP_003904541.1| HNH endonuclease [Thermoanaerobacter sp. X513] gb|ABY92535.1| HNH endonuclease [Thermoanaerobacter sp. X514] gb|EFK83727.1| HNH endonuclease [Thermoanaerobacter sp. X561] gb|ADN55250.1| HNH endonuclease [Thermoanaerobacter sp. X513] Length=119 Score = 44.7 bits (104), Expect = 0.015, Method: Compositional matrix adjust. Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 18/90 (20%) Query 173 PEGSRKPVEVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGN 222 PE ++K E R +K Y RDP + AW + + I CE C + Sbjct 24 PEHAKK--EASRYEK-YQRDPETRKRYGRAWKRIRDRYITAHPLCEECKRQGKL-----T 75 Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P EVHH++PL+ GG N +ALC CH Sbjct 76 PATEVHHILPLARGGTHDESNLMALCTPCH 105 >gb|EBS50833.1| hypothetical protein GOS_7426096 [marine metagenome] Length=204 Score = 44.7 bits (104), Expect = 0.015, Method: Compositional matrix adjust. Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 5/68 (7%) Query 194 MVKAWILQQSKGI-CENCGKNA-PFYLNDGNPYLEVHHVIPLSS---GGADTTDNCVALC 248 + K + +QQ G+ CE CG + Y G Y EVHH IP+S G + LC Sbjct 116 LKKDFFIQQHGGLYCEACGFDFFSKYGERGKNYAEVHHNIPISDPAFTGKTRLSDLSVLC 175 Query 249 PNCHRELH 256 NCHR +H Sbjct 176 SNCHRMIH 183 >ref|YP_003740994.1| endonuclease [Erwinia billingiae Eb661] emb|CAX59143.1| predicted endonuclease [Erwinia billingiae Eb661] Length=240 Score = 44.7 bits (104), Expect = 0.015, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 9/88 (10%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EG++ V V Y RDP + ++ C+ CG + Y G ++ VHH+ P Sbjct 139 EGAKTRVTVNS----YERDPRARQECIRHYGTACKGCGFDFGKVYGEHGKGFIHVHHIKP 194 Query 233 LSSGGA----DTTDNCVALCPNCHRELH 256 + + G D + + LCPNCH +H Sbjct 195 IHTLGEGYSIDPIVDLIPLCPNCHAMVH 222 >ref|YP_003398766.1| HNH endonuclease [Acidaminococcus fermentans DSM 20731] gb|ADB47451.1| HNH endonuclease [Acidaminococcus fermentans DSM 20731] Length=128 Score = 44.7 bits (104), Expect = 0.016, Method: Compositional matrix adjust. Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 15/95 (15%) Query 164 KLIKKTLSQPEGSRKPVEVERLQKVY--VRDPMVKAWILQQSKGICENCGKNAPFYLNDG 221 K+I K + E R P +R K + +RD V S +CE C KN + + + Sbjct 28 KIIAKRYEKYE--RSPATKKRYGKSWKKIRDAYV------SSHPLCELCLKNGRYVVAE- 78 Query 222 NPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 EVHH PL+ GG +N +ALC CH +H Sbjct 79 ----EVHHKKPLAEGGTHAWNNLIALCKACHARIH 109 >ref|ZP_00515756.1| RNA-directed DNA polymerase [Crocosphaera watsonii WH 8501] gb|EAM51190.1| RNA-directed DNA polymerase [Crocosphaera watsonii WH 8501] Length=578 Score = 44.7 bits (104), Expect = 0.016, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 35/65 (53%), Gaps = 5/65 (7%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 Y P + +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL Sbjct 505 TYTGTPARVSRLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGLDTYNNLQAL 559 Query 248 CPNCH 252 +CH Sbjct 560 HRHCH 564 >ref|ZP_00515528.1| RNA-directed DNA polymerase [Crocosphaera watsonii WH 8501] gb|EAM51471.1| RNA-directed DNA polymerase [Crocosphaera watsonii WH 8501] Length=594 Score = 44.7 bits (104), Expect = 0.016, Method: Compositional matrix adjust. Identities = 34/113 (30%), Positives = 53/113 (46%), Gaps = 8/113 (7%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKV---YVRDPMVKAWI 199 G+ + T + SL +K+++ L +PE S K Y P + + Sbjct 456 GKHGHWTFQTKEISLYYHAETKIMRHQLVKPEASYYDGNWSYWSKRRGNYTGTPTSVSKL 515 Query 200 LQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 L++ KG C C ++ F +D +EV H+IP S GG DT +N AL +CH Sbjct 516 LKKQKGRCPQCKQH--FTPDD---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 563 >ref|YP_001659893.1| RNA-directed DNA polymerase [Microcystis aeruginosa NIES-843] dbj|BAG04701.1| RNA-directed DNA polymerase [Microcystis aeruginosa NIES-843] Length=577 Score = 44.7 bits (104), Expect = 0.017, Method: Compositional matrix adjust. Identities = 24/60 (40%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P KA +L++ +G C CG Y DG+ LE H+IP S GG + DN L +CH Sbjct 501 PPEKAVLLKRQQGRCAYCG----LYFQDGD-ILETDHIIPKSKGGKNNRDNKQLLHRHCH 555 >ref|ZP_06966112.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] gb|EFH89223.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] Length=411 Score = 44.7 bits (104), Expect = 0.018, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 27/53 (50%), Gaps = 8/53 (15%) Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259 C++CGK LE HH+I GG DT N + LC CH++LH K Sbjct 194 CQHCGKQ--------KVRLEAHHLIFKGEGGKDTLTNLLTLCEACHKKLHQGK 238 >ref|YP_003343236.1| hypothetical protein Sros_7830 [Streptosporangium roseum DSM 43021] gb|ACZ90493.1| hypothetical protein Sros_7830 [Streptosporangium roseum DSM 43021] Length=419 Score = 44.7 bits (104), Expect = 0.018, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLND----GNPYLEVHHVIPLSSGGADTTDNCV 245 R K +L + KG CEN P +D G P L+V H+ + GG D + + Sbjct 323 ARSTPAKRAVLLRCKGACENPDCENPGRPSDTSVGGGPILDVDHIDDHAKGGRDYPELMI 382 Query 246 ALCPNCH 252 ALCPNCH Sbjct 383 ALCPNCH 389 >ref|ZP_04098620.1| HNH endonuclease [Bacillus thuringiensis serovar andalousiensis BGSC 4AW1] gb|EEM69685.1| HNH endonuclease [Bacillus thuringiensis serovar andalousiensis BGSC 4AW1] Length=258 Score = 44.7 bits (104), Expect = 0.018, Method: Compositional matrix adjust. Identities = 38/116 (32%), Positives = 56/116 (48%), Gaps = 11/116 (9%) Query 166 IKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPY 224 + + LS EG+RK V V + Y R + + ++ C C + Y + G + Sbjct 147 VPEQLSIMEGNRKTVVVNQ----YERSAVARRKCIEHHGCYCHVCHLDFKKQYGSLGKGF 202 Query 225 LEVHHVIPLSSGG----ADTTDNCVALCPNCHRELHY-SKNAKEL-IEMLYVNINR 274 + VHH IPLS G D ++ + +CPNCH LH S N L IE L V +N+ Sbjct 203 IHVHHKIPLSEIGDEYEVDYVNDLIPVCPNCHAMLHRKSMNGSFLTIEELKVLMNK 258 >ref|YP_002449968.1| DNA helicase, putative [Bacillus cereus AH820] gb|ACK88606.1| DNA helicase, putative [Bacillus cereus AH820] Length=278 Score = 44.7 bits (104), Expect = 0.018, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 7/63 (11%) Query 207 CENCGKNAPFYL--NDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKEL 264 C+ CG + N +EV H+I S GG +T DN LCPNCH +K + + Sbjct 196 CQVCGFKEEYIKANNKKGWIIEVDHIIEKSKGGGETFDNLWVLCPNCH-----AKKTRGI 250 Query 265 IEM 267 IE+ Sbjct 251 IEI 253 >ref|ZP_06178472.1| hypothetical protein VME_48560 [Vibrio harveyi 1DA3] gb|EEZ85251.1| hypothetical protein VME_48560 [Vibrio harveyi 1DA3] Length=266 Score = 44.7 bits (104), Expect = 0.019, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query 188 VYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIPLSSGG----ADTTD 242 Y R+P ++ + C CG + Y + G Y+ +HH +P+S G D Sbjct 173 TYERNPKLRRQAIAIHGATCAACGFDYGKVYGSIGEGYIHIHHKVPVSRLGISTLVDPEK 232 Query 243 NCVALCPNCHRELHYSKNAKELIEMLYV 270 + V LC NCH +H K+ +E L V Sbjct 233 DLVPLCANCHAMVHRKKDQTLSVEELKV 260 >gb|EBA72621.1| hypothetical protein GOS_352954 [marine metagenome] Length=450 Score = 44.7 bits (104), Expect = 0.019, Method: Compositional matrix adjust. Identities = 50/197 (25%), Positives = 73/197 (37%), Gaps = 28/197 (14%) Query 80 IHPGEYFTLIGNSPRDIRLKMCGYQAYFSRTGRKEIPSGNRTKRILINVPGIYSDSFWAS 139 +HPG + G L + A T + + +RT I P + A+ Sbjct 142 VHPGAIYLHDGAPFLVHELDLEARVARLEATDDRIVTRASRTTEIAAAGPLEHRQVRSAT 201 Query 140 IIRGELSELSQPTDDESLLNMRVSKLIKKTLSQPEGS---------RKPVEVERLQK--V 188 + GEL T L L + LS P + P VERL+ Sbjct 202 VAVGELLVTETVTRYRRLRRSTRETLGRFPLSLPPSTLLTRGYAFAPNPEVVERLRATGA 261 Query 189 YVRD--------PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGG--- 237 + D P ++A +LQ+ C +CG A + + VHHVIP + Sbjct 262 WTNDANDYGAAWPRIRASVLQRDARSCRHCGTAAGRGI-----VMHVHHVIPFRAFATAR 316 Query 238 -ADTTDNCVALCPNCHR 253 A+ +N V LCP CHR Sbjct 317 EANQLENLVTLCPACHR 333 >ref|ZP_05721581.1| conserved hypothetical protein [Vibrio mimicus VM603] gb|EEW05886.1| conserved hypothetical protein [Vibrio mimicus VM603] Length=208 Score = 44.7 bits (104), Expect = 0.019, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 44/97 (45%), Gaps = 14/97 (14%) Query 189 YVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGADTTDNCVA 246 ++RD + + +++ C+ C F L +G PY E HH+ PL G D N + Sbjct 106 FIRDSKLSQLVKKKNNYKCQICA--FTFLLPNGKPYAEAHHLKPLGKEHDGPDIEGNLIC 163 Query 247 LCPNCHRELHYS----------KNAKELIEMLYVNIN 273 +CPN H L Y KN+K I +++ N Sbjct 164 VCPNHHAMLDYCSLKLDVNAIVKNSKHEIMKEFIDYN 200 >gb|EBN63893.1| hypothetical protein GOS_8213048 [marine metagenome] Length=325 Score = 44.3 bits (103), Expect = 0.019, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 9/66 (13%) Query 192 DPM---VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 DP+ V+ +L+++KG CE CG +++ L+V H++P S GG++ N +LC Sbjct 124 DPIPGSVRYEVLKKAKGKCELCG------ISNKEKSLDVDHILPRSKGGSNDISNLQSLC 177 Query 249 PNCHRE 254 C+R+ Sbjct 178 YTCNRQ 183 >ref|ZP_08558482.1| hypothetical protein HLRTI_01252 [Halorhabdus tiamatea SARL4B] gb|EGM36666.1| hypothetical protein HLRTI_01252 [Halorhabdus tiamatea SARL4B] Length=90 Score = 44.3 bits (103), Expect = 0.020, Method: Compositional matrix adjust. Identities = 20/44 (45%), Positives = 28/44 (63%), Gaps = 2/44 (4%) Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELH--YSKNAKELIE 266 LE HH+IP G D+ +N V +CPNCH+ L Y ++ EL+E Sbjct 18 LEEHHLIPARRNGPDSDENLVTVCPNCHKALENIYDRSFWELVE 61 >ref|ZP_07959296.1| HNH endonuclease domain-containing protein [Lachnospiraceae bacterium 8_1_57FAA] ref|ZP_08618834.1| hypothetical protein HMPREF0990_01228 [Lachnospiraceae bacterium 1_1_57FAA] gb|EFV19542.1| HNH endonuclease domain-containing protein [Lachnospiraceae bacterium 8_1_57FAA] gb|EGN46492.1| hypothetical protein HMPREF0990_01228 [Lachnospiraceae bacterium 1_1_57FAA] Length=86 Score = 44.3 bits (103), Expect = 0.020, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 33/57 (57%), Gaps = 5/57 (8%) Query 206 ICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAK 262 +CE C K + + EVHH++PL+ GG++ N ++LC +CH ++H + + Sbjct 35 LCEQCLKEGRYVAVE-----EVHHIVPLAEGGSNDESNLMSLCRSCHEKIHRERGDR 86 >ref|YP_692355.1| reverse transcriptase/maturase-like protein [Alcanivorax borkumensis SK2] emb|CAL16083.1| reverse transcriptase/maturase homolog [Alcanivorax borkumensis SK2] Length=552 Score = 44.3 bits (103), Expect = 0.020, Method: Compositional matrix adjust. Identities = 18/30 (60%), Positives = 20/30 (66%), Gaps = 0/30 (0%) Query 227 VHHVIPLSSGGADTTDNCVALCPNCHRELH 256 +HHVI GG D DN V L PNCHR+LH Sbjct 518 IHHVIEQHKGGTDKLDNLVLLHPNCHRQLH 547 >ref|ZP_00516851.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM50073.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=596 Score = 44.3 bits (103), Expect = 0.020, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 12/93 (12%) Query 165 LIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +++ T +PE S P + + + Y P A +L++ KGIC C + F Sbjct 480 ILRHTWVKPEAS--PYDGNWTYWSKRRGTYSGTPTRVAKLLKKQKGICPQCKQY--FTPE 535 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 D +EV H+IP S GG DT +N AL +CH Sbjct 536 D---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 565 >ref|ZP_03104429.1| gp45 [Bacillus cereus W] gb|EDX54271.1| gp45 [Bacillus cereus W] Length=375 Score = 44.3 bits (103), Expect = 0.021, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 11/79 (13%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPL 233 +G K E RL+K R+ K ++L G C CG A + H+IP Sbjct 108 DGLEKIREQNRLRKQKQREKE-KQYLLGNDMGTCAYCGDQAN----------TLDHLIPK 156 Query 234 SSGGADTTDNCVALCPNCH 252 S GG DT +NCV+ C C+ Sbjct 157 SHGGLDTQENCVSCCKQCN 175 >ref|YP_001038057.1| HNH endonuclease [Clostridium thermocellum ATCC 27405] gb|ABN52864.1| HNH endonuclease [Clostridium thermocellum ATCC 27405] Length=119 Score = 44.3 bits (103), Expect = 0.021, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 15/74 (20%) Query 189 YVRDPMVKAWILQQSKGI----------CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGA 238 Y RDP + ++ K I CE C K P EVHH+IPLS GG Sbjct 37 YERDPQTRKRYDRRWKRIRDRYISEHPLCEECQKYGRL-----TPAEEVHHIIPLSKGGT 91 Query 239 DTTDNCVALCPNCH 252 + N ++LC CH Sbjct 92 NADSNLMSLCKQCH 105 >ref|ZP_00516498.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM50417.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=596 Score = 44.3 bits (103), Expect = 0.021, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 12/93 (12%) Query 165 LIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +++ T +PE S P + + + Y P A +L++ KGIC C + F Sbjct 480 ILRHTWVKPEAS--PYDGNWTYWSKRRGTYSGTPTRVAKLLKKQKGICPQCKQY--FTPE 535 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 D +EV H+IP S GG DT +N AL +CH Sbjct 536 D---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 565 >gb|EBG33586.1| hypothetical protein GOS_9450142 [marine metagenome] Length=104 Score = 44.3 bits (103), Expect = 0.021, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 10/72 (13%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 V+ + ++ C CG AP N L V HV+P+S GG D DN V C C Sbjct 33 VRFSVFKRDSFACRYCGATAP------NVQLHVDHVVPVSEGGQDDLDNLVTACAAC--- 83 Query 255 LHYSKNAKELIE 266 ++ K A+ L E Sbjct 84 -NFGKGARNLGE 94 >ref|ZP_04632181.1| HNH nuclease [Yersinia frederiksenii ATCC 33641] gb|EEQ15279.1| HNH nuclease [Yersinia frederiksenii ATCC 33641] Length=298 Score = 44.3 bits (103), Expect = 0.021, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 2/66 (3%) Query 192 DPMVKAWILQQSKGICENCGKNAPFYL-NDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 DP V+ +L++ C NCG +D LE+HH+ GG +T +N + LC Sbjct 215 DP-VRVKVLERDHHSCRNCGWQYQLKKPSDPRSLLELHHIEHHVDGGENTVENLITLCNV 273 Query 251 CHRELH 256 CH E+H Sbjct 274 CHDEVH 279 >ref|ZP_00517863.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM49059.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=596 Score = 44.3 bits (103), Expect = 0.022, Method: Compositional matrix adjust. Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 12/93 (12%) Query 165 LIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +++ T +PE S P + + + Y P A +L++ KGIC C + F Sbjct 480 ILRHTWVKPEAS--PYDGNWTYWSKRRGTYSGTPTRVAKLLKKQKGICPQCKQY--FTPE 535 Query 220 DGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 D +EV H+IP S GG DT +N AL +CH Sbjct 536 D---LIEVDHIIPKSKGGKDTYNNLQALHRHCH 565 >ref|ZP_08432327.1| RNA-directed DNA polymerase [Lyngbya majuscula 3L] gb|EGJ28487.1| RNA-directed DNA polymerase [Lyngbya majuscula 3L] Length=570 Score = 44.3 bits (103), Expect = 0.024, Method: Compositional matrix adjust. Identities = 35/119 (29%), Positives = 60/119 (50%), Gaps = 13/119 (10%) Query 152 TDDESLLNMRVSKLIKKTLSQPEGSRKPVE---VERLQKVYVRDPMV--KAWILQQSKGI 206 ++D+ L +K+I+ + G R P + V L++V M K +L++ +G Sbjct 454 SEDQFLPKHAKTKIIRH--KKVAGVRSPYDGNLVYWLERVRKHPEMTSQKGKLLKRQEGK 511 Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK-NAKEL 264 C +CG DG+ +E HH++P + GG D N L +CH ++H + N+KEL Sbjct 512 CTHCG----LTFRDGD-LMETHHILPRALGGKDNIGNLELLHLHCHDKIHGKQINSKEL 565 >ref|ZP_03841307.1| hypothetical protein HMPREF0693_2198 [Proteus mirabilis ATCC 29906] gb|EEI47860.1| hypothetical protein HMPREF0693_2198 [Proteus mirabilis ATCC 29906] Length=98 Score = 44.3 bits (103), Expect = 0.024, Method: Compositional matrix adjust. Identities = 22/48 (45%), Positives = 26/48 (54%), Gaps = 5/48 (10%) Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 C CG F DG E+ H+IPL GG DT +NC LC CHR+ Sbjct 48 CAACGSLLAF--PDG---FELDHIIPLFKGGKDTIENCQVLCIECHRK 90 >ref|ZP_00514784.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM52622.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=148 Score = 44.3 bits (103), Expect = 0.024, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 12/115 (10%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKA 197 G+ + + T++ L +++ + L +P+ S P + + + Y P + Sbjct 27 GKYGKWTFQTEEAVLYYHAETEIKRHQLVKPDAS--PYDGNWTYWSKRRGTYTGTPARVS 84 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL +CH Sbjct 85 RLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGLDTYNNLQALHRHCH 134 >gb|ECA33447.1| hypothetical protein GOS_5260325 [marine metagenome] Length=161 Score = 44.3 bits (103), Expect = 0.024, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 50/113 (44%), Gaps = 9/113 (7%) Query 149 SQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICE 208 S+PT +S N ++ + + S EG K +R Y R ++ + C Sbjct 24 SRPTPKKSAKNEDLNDISQGLESNEEGGSK----KRYVTQYERSNHNRSLAIAIHGESCA 79 Query 209 NCGKN-APFYLNDGNPYLEVHHVIPLSSGGA----DTTDNCVALCPNCHRELH 256 CG N FY + Y++VHHV+P+S D + + LC NCH +H Sbjct 80 ACGFNFGAFYGDYAEGYIQVHHVVPVSELDGPIKPDPETDLIPLCANCHAVVH 132 >ref|ZP_06968411.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] gb|EFH85951.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] Length=432 Score = 43.9 bits (102), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 8/63 (12%) Query 195 VKAWILQQSKGICENC-GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 KA++L + +C++C GK+ LEVHH+I S G+D N + LC CH Sbjct 189 TKAYVLTRDGYLCQHCKGKSK-------ETRLEVHHIIFRSQNGSDEEANLLTLCKTCHD 241 Query 254 ELH 256 LH Sbjct 242 GLH 244 >ref|YP_002462285.1| HNH endonuclease [Chloroflexus aggregans DSM 9485] gb|ACL23849.1| HNH endonuclease [Chloroflexus aggregans DSM 9485] Length=174 Score = 43.9 bits (102), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 +R P + + + + C+ CGK G YL + HVIP S GG T +N V C Sbjct 73 LRLPCSRRGVFARDRETCQYCGKQ------PGRAYLTMDHVIPRSQGGQTTWENVVTACR 126 Query 250 NC-HRE 254 +C HR+ Sbjct 127 DCNHRK 132 >ref|YP_117808.1| hypothetical protein nfa15980 [Nocardia farcinica IFM 10152] dbj|BAD56444.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=760 Score = 43.9 bits (102), Expect = 0.025, Method: Compositional matrix adjust. Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 9/59 (15%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 +KA + Q+ G C CG YLE H+IPLS GGA + N LC C+R Sbjct 705 IKAEVWQRDGGRCVECGSGH---------YLEFDHIIPLSRGGATSAANLQILCRACNR 754 >gb|EGL98736.1| paclitaxel/taxanoid biosynthesis susceptibility protein TS1 [Lactobacillus salivarius NIAS840] Length=434 Score = 43.9 bits (102), Expect = 0.026, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 8/58 (13%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 VK ++L + C+ C K + ++HH+I S GG +T DN + +C NCH Sbjct 186 VKQFVLARDNYTCQVCKKKGGKF--------KIHHIIYRSLGGTNTVDNLITVCSNCH 235 >ref|YP_001100121.1| putative restriction endonuclease [Herminiimonas arsenicoxydans] emb|CAL61996.1| Putative restriction endonuclease [Herminiimonas arsenicoxydans] Length=269 Score = 43.9 bits (102), Expect = 0.026, Method: Compositional matrix adjust. Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPLSSGGAD---TTDNCVALCPNCHRELH 256 C+ C KN F G Y+E HH IP+SS + + + LCPNCH+ +H Sbjct 194 CDVCQKN--FEKEYGVKYIEAHHKIPISSFSSKHPVKSSDFALLCPNCHKAIH 244 >ref|YP_001285917.1| hypothetical protein [Lactobacillus phage LL-H] gb|AAL77545.1| hypothetical protein [Lactobacillus phage LL-H] Length=112 Score = 43.9 bits (102), Expect = 0.026, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 15/84 (17%) Query 173 PEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIP 232 P+G R + + +++YVRD KGIC CGK+ F N + H+ P Sbjct 26 PKGQRPKISKAKRKRIYVRD-----------KGICAYCGKHLEFKPNG----FHIDHIKP 70 Query 233 LSSGGADTTDNCVALCPNCHRELH 256 L+ GG + N C C+ H Sbjct 71 LAKGGNNEDSNLTVSCRECNLSKH 94 >gb|ECT47599.1| hypothetical protein GOS_5822885 [marine metagenome] Length=195 Score = 43.9 bits (102), Expect = 0.026, Method: Compositional matrix adjust. Identities = 23/54 (42%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query 207 CENCGKNA-PFYLNDGNPYLEVHHVIPLSSGGADT---TDNCVALCPNCHRELH 256 CE C N FY G ++E HH IPLS T T + +C NCHR LH Sbjct 132 CEVCDFNFHDFYGQRGKEFIECHHKIPLSKLNPKTITFTKDLAVVCSNCHRMLH 185 >gb|EBJ67529.1| hypothetical protein GOS_8858845 [marine metagenome] Length=197 Score = 43.9 bits (102), Expect = 0.027, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 9/66 (13%) Query 192 DPM---VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALC 248 DP+ ++ +L+++KG CE CG +++ L+V H+IP S GG++ N +LC Sbjct 53 DPIPGSIRYEVLKRAKGKCELCG------ISNKEKSLDVDHIIPRSKGGSNDISNLQSLC 106 Query 249 PNCHRE 254 C+R+ Sbjct 107 YTCNRQ 112 >ref|ZP_04161902.1| Hnh endonuclease [Bacillus mycoides Rock1-4] gb|EEM06206.1| Hnh endonuclease [Bacillus mycoides Rock1-4] Length=206 Score = 43.9 bits (102), Expect = 0.027, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 7/75 (9%) Query 204 KGICENCGKN-APFYLNDGNPYLEVHHVIPLSS---GGADTTDNCVALCPNCHRELHYSK 259 K CE C + Y G Y+E HHVIP+S G ++ + +C NCHR LH K Sbjct 132 KLFCEICKFDYKEKYGELGEDYIEGHHVIPVSELEEGSKTKVEDIILVCANCHRMLHRKK 191 Query 260 ---NAKELIEMLYVN 271 + ++L E+L+ N Sbjct 192 PWLSKEQLKEILHSN 206 >gb|EGL98264.1| paclitaxel/taxanoid biosynthesis susceptibility protein TS1 [Lactobacillus salivarius NIAS840] Length=318 Score = 43.9 bits (102), Expect = 0.027, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 8/58 (13%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 VK ++L + C+ C K L++HH+I S GG +T DN + +C NCH Sbjct 186 VKQFVLARDNYTCQVCKKKGG--------KLKIHHIIYRSLGGTNTVDNLITVCSNCH 235 >ref|YP_001520477.1| RNA-directed DNA polymerase [Acaryochloris marina MBIC11017] ref|YP_001520907.1| RNA-directed DNA polymerase [Acaryochloris marina MBIC11017] ref|YP_001521367.1| RNA-directed DNA polymerase [Acaryochloris marina MBIC11017] 9 more sequence titles Length=576 Score = 43.9 bits (102), Expect = 0.028, Method: Compositional matrix adjust. Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 9/65 (13%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYS 258 +L++ KG C CG F+ + LEV H++P S GG D N L HR HY Sbjct 512 LLKKQKGKCAQCGM---FFREED--LLEVDHILPTSMGGLDVYKNLQLL----HRHCHYV 562 Query 259 KNAKE 263 K AKE Sbjct 563 KTAKE 567 >ref|ZP_00517871.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM49041.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=175 Score = 43.9 bits (102), Expect = 0.028, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 12/115 (10%) Query 143 GELSELSQPTDDESLLNMRVSKLIKKTLSQPEGSRKPVE-----VERLQKVYVRDPMVKA 197 G+ + + T++ L +++ + L +P+ S P + + + Y P + Sbjct 54 GKYGKWTFQTEEAVLYYHAETEIKRHQLVKPDAS--PYDGNWTYWSKRRGTYTGTPARVS 111 Query 198 WILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL +CH Sbjct 112 RLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGLDTYNNLQALHRHCH 161 >ref|ZP_00516633.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM50256.1| RNA-directed DNA polymerase (Reverse transcriptase):HNH endonuclease [Crocosphaera watsonii WH 8501] Length=441 Score = 43.9 bits (102), Expect = 0.028, Method: Compositional matrix adjust. Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 5/60 (8%) Query 193 PMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 P A +L++ KGIC C ++ F D +EV H+IP S GG DT +N AL +CH Sbjct 373 PTRVAKLLKKQKGICPQCKQH--FTPED---LIEVDHIIPKSKGGLDTYNNLQALHRHCH 427 >ref|ZP_08305237.1| HNH endonuclease domain protein [Klebsiella sp. MS 92-3] gb|EGF62622.1| HNH endonuclease domain protein [Klebsiella sp. MS 92-3] Length=212 Score = 43.9 bits (102), Expect = 0.029, Method: Compositional matrix adjust. Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYL 225 + T+ EG+ V V R Y RD + L+ C+ CG + A Y G ++ Sbjct 103 QTTMEFVEGAAMQVVVNR----YERDRQARQAALRLHGCRCQVCGLDMASRYGEIGQGFI 158 Query 226 EVHHVIPLSSGGADTTDN----CVALCPNCHRELH 256 +HH+IPLS D N + +CPNCH LH Sbjct 159 HIHHLIPLSGIKQDYRLNPETDLIPVCPNCHAMLH 193 >ref|ZP_01675841.1| HNH endonuclease domain protein [Vibrio cholerae 2740-80] gb|EAX59737.1| HNH endonuclease domain protein [Vibrio cholerae 2740-80] Length=210 Score = 43.9 bits (102), Expect = 0.029, Method: Compositional matrix adjust. Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 20/134 (14%) Query 137 WASIIRGELSELSQPTD---DESLLNMRVSKL-------------IKKTLSQPEGSRKPV 180 W ++IR + +LS +D + L V+ L K P G+++P Sbjct 39 WKAVIRRRIQDLSSDSDGFKNGQDLFYSVNGLGGGMWGLRNKLAYTPKAADLPTGTKEPE 98 Query 181 EVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSS--GGA 238 +RD + + C+ CG L +G Y E HH+IPL + G+ Sbjct 99 REYTTTYRVLRDTNLARKLKLLYNNSCQICG--LQIQLPNGKLYSEAHHIIPLGNPHHGS 156 Query 239 DTTDNCVALCPNCH 252 DT +N + LCPN H Sbjct 157 DTPENIIVLCPNHH 170 >ref|YP_002917583.1| hypothetical protein KP1_0666 [Klebsiella pneumoniae NTUH-K2044] dbj|BAH61516.1| hypothetical protein KP1_0666 [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Length=212 Score = 43.9 bits (102), Expect = 0.030, Method: Compositional matrix adjust. Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYL 225 + T+ EG+ V V R Y RD + L+ C+ CG + A Y G ++ Sbjct 103 QTTMEFVEGAAMQVVVNR----YERDRQARQAALRLHGCRCQVCGLDMASRYGEIGQGFI 158 Query 226 EVHHVIPLSSGGADTTDN----CVALCPNCHRELH 256 +HH+IPLS D N + +CPNCH LH Sbjct 159 HIHHLIPLSGIKQDYRLNPETDLIPVCPNCHAMLH 193 >ref|YP_002472815.1| hypothetical protein CKR_2350 [Clostridium kluyveri NBRC 12016] dbj|BAH07401.1| hypothetical protein [Clostridium kluyveri NBRC 12016] Length=126 Score = 43.9 bits (102), Expect = 0.030, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 16/82 (19%) Query 181 EVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHV 230 E R +K Y RDP + AW + + I CE C + P EVHH+ Sbjct 37 EAARYEK-YDRDPATRKRYGRAWKRIRDRYIAAHPLCEECKRQGKL-----TPATEVHHI 90 Query 231 IPLSSGGADTTDNCVALCPNCH 252 +PL+ GG N ++LC +CH Sbjct 91 LPLARGGTHDRSNLMSLCTSCH 112 >ref|NP_301904.1| hypothetical protein ML1254 [Mycobacterium leprae TN] ref|YP_002503534.1| hypothetical protein MLBr_01254 [Mycobacterium leprae Br4923] emb|CAB43161.1| hypothetical protein MLCB1610.15 [Mycobacterium leprae] emb|CAC31635.1| conserved hypothetical protein [Mycobacterium leprae] emb|CAR71349.1| conserved hypothetical protein [Mycobacterium leprae Br4923] Length=215 Score = 43.9 bits (102), Expect = 0.030, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 14/81 (17%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R PM +A ++ + + C CG A V HV+P S GG + +NCVA C Sbjct 114 ARVPMTRAALMHRDRFCCAYCGAKAD----------TVDHVVPRSRGGDHSWENCVACCS 163 Query 250 NCHRELHYSKNAKELIEMLYV 270 C ++ K K L E+ +V Sbjct 164 TC----NHRKGDKLLTELGWV 180 >ref|ZP_06973729.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] gb|EFH81796.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] Length=432 Score = 43.9 bits (102), Expect = 0.030, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 8/63 (12%) Query 195 VKAWILQQSKGICENC-GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 KA++L + +C+ C GK+ + LEVHH+I S G+D N + LC CH Sbjct 189 TKAYVLTRDGYLCQQCKGKSK-------DRRLEVHHIIFRSRNGSDEEANLLTLCKTCHD 241 Query 254 ELH 256 LH Sbjct 242 GLH 244 >ref|YP_001396035.1| hypothetical protein CKL_2652 [Clostridium kluyveri DSM 555] gb|EDK34664.1| Phage-related protein [Clostridium kluyveri DSM 555] Length=119 Score = 43.9 bits (102), Expect = 0.030, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 16/82 (19%) Query 181 EVERLQKVYVRDPMVK-----AWILQQSKGI-----CENCGKNAPFYLNDGNPYLEVHHV 230 E R +K Y RDP + AW + + I CE C + P EVHH+ Sbjct 30 EAARYEK-YDRDPATRKRYGRAWKRIRDRYIAAHPLCEECKRQGKL-----TPATEVHHI 83 Query 231 IPLSSGGADTTDNCVALCPNCH 252 +PL+ GG N ++LC +CH Sbjct 84 LPLARGGTHDRSNLMSLCTSCH 105 >ref|YP_002017592.1| HNH nuclease [Pelodictyon phaeoclathratiforme BU-1] gb|ACF42975.1| HNH nuclease [Pelodictyon phaeoclathratiforme BU-1] Length=309 Score = 43.9 bits (102), Expect = 0.031, Method: Compositional matrix adjust. Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 0/58 (0%) Query 199 ILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 +LQ+ C+ CG + + +LE HH+ GG +T +N V LC CH + H Sbjct 250 VLQRDDYRCQQCGWHQEMWNQSDPRHLEAHHIKQHVEGGENTKENLVTLCNICHDKEH 307 >ref|YP_001338337.1| hypothetical protein KPN_04720 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] gb|ABR80070.1| hypothetical protein KPN_04720 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] Length=212 Score = 43.9 bits (102), Expect = 0.031, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 9/95 (9%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYL 225 + T+ EG+ V + R Y RD + L+ C+ CG + A Y G ++ Sbjct 103 QTTMEYVEGAAMQVVINR----YERDRQARQAALRLHGCRCQVCGLDMASRYGEIGQGFI 158 Query 226 EVHHVIPLSSGGADTTDN----CVALCPNCHRELH 256 +HH+IPLS D N + +CPNCH LH Sbjct 159 HIHHLIPLSGIKQDYRLNPETDLIPVCPNCHAMLH 193 >ref|YP_004516156.1| HNH endonuclease [Desulfotomaculum kuznetsovii DSM 6115] gb|AEG14355.1| HNH endonuclease [Desulfotomaculum kuznetsovii DSM 6115] Length=388 Score = 43.9 bits (102), Expect = 0.032, Method: Compositional matrix adjust. Identities = 17/32 (53%), Positives = 23/32 (71%), Gaps = 0/32 (0%) Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 L+ HH++P S GG+DT N V LC CHR++H Sbjct 196 LQRHHLVPRSKGGSDTPMNQVVLCEKCHRKIH 227 >ref|YP_002545821.1| hypothetical protein Arad_4103 [Agrobacterium radiobacter K84] gb|ACM27888.1| conserved hypothetical protein [Agrobacterium radiobacter K84] Length=219 Score = 43.9 bits (102), Expect = 0.032, Method: Compositional matrix adjust. Identities = 34/89 (38%), Positives = 44/89 (49%), Gaps = 10/89 (11%) Query 171 SQPEGS--RKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVH 228 S+ EG+ K V R+ + V VKA L SK C+ CG + L DG Y E H Sbjct 97 SEIEGAVLAKEVTTNRIIRDTVMTCKVKA--LHHSK--CQICGTS--ISLPDGRAYSEAH 150 Query 229 HVIPLSSG--GADTTDNCVALCPNCHREL 255 H+IPL + G D N + +CPN H L Sbjct 151 HIIPLGAPHRGPDIPSNIIIVCPNHHAML 179 >ref|ZP_08431996.1| group II catalytic intron [Lyngbya majuscula 3L] gb|EGJ29004.1| group II catalytic intron [Lyngbya majuscula 3L] Length=327 Score = 43.9 bits (102), Expect = 0.032, Method: Compositional matrix adjust. Identities = 17/39 (43%), Positives = 24/39 (61%), Gaps = 0/39 (0%) Query 225 LEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSKNAKE 263 +E HH+IP+ GG++ DN V L CH+ LH K K+ Sbjct 287 IETHHIIPIKEGGSNLADNLVHLHKACHKLLHGKKKTKQ 325 >ref|ZP_01222701.1| hypothetical protein P3TCK_08708 [Photobacterium profundum 3TCK] gb|EAS40754.1| hypothetical protein P3TCK_08708 [Photobacterium profundum 3TCK] Length=244 Score = 43.9 bits (102), Expect = 0.032, Method: Compositional matrix adjust. Identities = 33/102 (32%), Positives = 50/102 (49%), Gaps = 9/102 (8%) Query 171 SQPEGSRKPVEVERLQK-VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHH 229 S PEG K V + ++ R+ ++ + L S +CE + A Y G ++ VHH Sbjct 138 SFPEGMAKKVVINSFERNKTARNSCIEEYGLSCS--VCEFNFEKA--YGELGTGFIHVHH 193 Query 230 VIPLSSGG----ADTTDNCVALCPNCHRELHYSKNAKELIEM 267 V+ +SS G D + V +CPNCH LH K A + E+ Sbjct 194 VVDISSIGYAYQVDPKKDLVPVCPNCHAMLHKRKPAFTVQEL 235 >ref|YP_961686.1| HNH nuclease [Shewanella sp. W3-18-1] gb|ABM23132.1| HNH nuclease [Shewanella sp. W3-18-1] Length=387 Score = 43.5 bits (101), Expect = 0.033, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 12/90 (13%) Query 183 ERLQKVYVRDPMVKAWILQQSKGICENC---GKNAPFYLNDGNPYLEVHHVIPLSSGGAD 239 ++L K + ++A ++ + C C G+ P LE+ + P + GG+ Sbjct 4 QKLNKRRIPSVAMRAKLIAKHNNQCAMCTISGEEIP---------LELASITPFNEGGSM 54 Query 240 TTDNCVALCPNCHRELHYSKNAKELIEMLY 269 T +N + LCPNCHR + E + LY Sbjct 55 TEENFLLLCPNCHRYMTMGPKEIEFVNFLY 84 >ref|YP_358357.1| HNH endonuclease family protein [Pelobacter carbinolicus DSM 2380] gb|ABA90187.1| HNH endonuclease family protein [Pelobacter carbinolicus DSM 2380] Length=96 Score = 43.5 bits (101), Expect = 0.033, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 31/69 (44%), Gaps = 7/69 (10%) Query 184 RLQKVYVRDPMVKAWILQQ-SKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTD 242 R ++ RD W + + GIC CGK G L + H++PL GG T Sbjct 12 RRERQKARDLRRSQWWKNRIATGICHYCGKQV------GARALTLDHIVPLVRGGRSTKG 65 Query 243 NCVALCPNC 251 NCVA C C Sbjct 66 NCVAACKEC 74 >gb|EFZ52303.1| HNH endonuclease family protein [Shigella sonnei 53G] Length=247 Score = 43.5 bits (101), Expect = 0.034, Method: Compositional matrix adjust. Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 12/110 (10%) Query 174 EGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYLEVHHVIP 232 EG++K V V Y RDP + + C C N Y ++ VHH+ P Sbjct 142 EGAKKQVTVNS----YERDPKARQACIDHHGTSCGCCEFNFEKVYGEHAKGFIHVHHIKP 197 Query 233 LSSGGADTTDN----CVALCPNCHRELHYSK---NAKELIEMLYVNINRL 275 L + G D N V LCPNCH +H + + L +L+ + N++ Sbjct 198 LHTVGEDYEVNPITDMVPLCPNCHAMVHRGNEVLSVESLKALLFKDSNKI 247 >ref|ZP_06974220.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] gb|EFH82287.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] Length=432 Score = 43.5 bits (101), Expect = 0.034, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 8/63 (12%) Query 195 VKAWILQQSKGICENC-GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 KA++L + +C+ C GK+ + LEVHH+I S G+D N + LC CH Sbjct 189 TKAYVLTRDGYLCQQCKGKSK-------DRRLEVHHIIFRSRNGSDEEANLLTLCKTCHD 241 Query 254 ELH 256 LH Sbjct 242 GLH 244 >gb|EBO44951.1| hypothetical protein GOS_8078522 [marine metagenome] Length=222 Score = 43.5 bits (101), Expect = 0.034, Method: Compositional matrix adjust. Identities = 21/60 (35%), Positives = 33/60 (55%), Gaps = 6/60 (10%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 ++ +L ++K CE+CG +++ LEV H+IP S GG D N ALC C+ + Sbjct 99 IRYKVLLRAKSKCESCG------ISNKEKALEVDHIIPRSKGGKDVLSNFQALCYTCNAQ 152 >ref|ZP_03130774.1| HNH endonuclease [Chthoniobacter flavus Ellin428] gb|EDY18554.1| HNH endonuclease [Chthoniobacter flavus Ellin428] Length=212 Score = 43.5 bits (101), Expect = 0.035, Method: Compositional matrix adjust. Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query 160 MRVSKLIKKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKNAPFYLN 219 +R +SQP S+ ++R+ ++ +RD + + + IC+ CG + Sbjct 80 VRCDARAANDISQP--SQPDRVLQRISRI-IRDTAISSELKLLYDHICQLCGTQ--LVVC 134 Query 220 DGNPYLEVHHVIPLS--SGGADTTDNCVALCPNCHRELHYS 258 D Y E HH+ PL G+DT DN + +CPNCH L Y+ Sbjct 135 D-RLYSEAHHIRPLGRPHDGSDTRDNLLCVCPNCHVLLDYA 174 >ref|ZP_06973478.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] gb|EFH81545.1| HNH endonuclease [Ktedonobacter racemifer DSM 44963] Length=392 Score = 43.5 bits (101), Expect = 0.035, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 8/63 (12%) Query 195 VKAWILQQSKGICENC-GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 KA++L + C++C GK+ + LEVHH+I S G+D N + LC CH Sbjct 187 TKAYVLTRDGYTCQHCQGKSK-------DQRLEVHHIIFRSQHGSDEESNLLTLCKTCHD 239 Query 254 ELH 256 LH Sbjct 240 ALH 242 >ref|YP_001702306.1| HNH endonuclease precursor [Mycobacterium abscessus ATCC 19977] emb|CAM61652.1| Probable HNH endonuclease precursor [Mycobacterium abscessus] Length=183 Score = 43.5 bits (101), Expect = 0.035, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 11/66 (16%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R PM +A ++ + + C CG A + HVIP S GGA + +NCVA C Sbjct 82 ARVPMTRAALMHRDRFRCAYCGGRAD----------TIDHVIPRSKGGAHSWENCVACCS 131 Query 250 NC-HRE 254 +C HR+ Sbjct 132 SCNHRK 137 >ref|ZP_01903583.1| HNH nuclease [Roseobacter sp. AzwK-3b] gb|EDM71079.1| HNH nuclease [Roseobacter sp. AzwK-3b] Length=115 Score = 43.5 bits (101), Expect = 0.035, Method: Compositional matrix adjust. Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 7/57 (12%) Query 196 KAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 +AW ++++G CE CG LN G+ E H IP GG ++ +NCV LC CH Sbjct 13 QAW--ERARGKCEECG----VKLNVGD-RREFDHRIPCGLGGDNSLENCVVLCAACH 62 >ref|ZP_06018175.1| conserved hypothetical protein [Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884] gb|EEW38751.1| conserved hypothetical protein [Klebsiella pneumoniae subsp. rhinoscleromatis ATCC 13884] Length=212 Score = 43.5 bits (101), Expect = 0.036, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 45/95 (47%), Gaps = 9/95 (9%) Query 167 KKTLSQPEGSRKPVEVERLQKVYVRDPMVKAWILQQSKGICENCGKN-APFYLNDGNPYL 225 + T+ EG+ V V R Y RD + L+ C+ CG + A Y + G ++ Sbjct 103 QTTMEFVEGAAMQVVVNR----YERDRQARQAALRLHGCRCQVCGLDMASRYGDIGQGFI 158 Query 226 EVHHVIPLSSGGADTTDN----CVALCPNCHRELH 256 +HH+IPL+ D N + +CPNCH LH Sbjct 159 HIHHLIPLAGIKQDYRLNPETDLIPVCPNCHAMLH 193 >ref|YP_001813876.1| HNH endonuclease [Exiguobacterium sibiricum 255-15] gb|ACB60859.1| HNH endonuclease [Exiguobacterium sibiricum 255-15] Length=418 Score = 43.5 bits (101), Expect = 0.037, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 14/81 (17%) Query 195 VKAWILQQSKGICENC-GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHR 253 V+ ++ + K +C++C GK+ LN VHH+ +GG D DN + LC CH+ Sbjct 182 VREYVFFRDKHMCQHCKGKSKDKILN-------VHHIESRRTGG-DAPDNLITLCETCHK 233 Query 254 ELHYSKNAKELIEMLYVNINR 274 ++H KE +E L+ +R Sbjct 234 KIH-----KENLEHLFQRKSR 249 >ref|YP_004451260.1| RNA-directed DNA polymerase [Haliscomenobacter hydrossis DSM 1100] gb|AEE54387.1| RNA-directed DNA polymerase (Reverse transcriptase) [Haliscomenobacter hydrossis DSM 1100] Length=576 Score = 43.5 bits (101), Expect = 0.037, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query 191 RDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPN 250 R ++ W + KGIC C + N HH++ GG DT+DN + L P+ Sbjct 499 RKQLIYLW--NEQKGICPICQQRITTETGWHN-----HHIVWRVHGGKDTSDNRILLHPD 551 Query 251 CHRELH 256 CHR++H Sbjct 552 CHRKVH 557 >ref|ZP_00516558.1| HNH endonuclease [Crocosphaera watsonii WH 8501] gb|EAM50346.1| HNH endonuclease [Crocosphaera watsonii WH 8501] Length=165 Score = 43.5 bits (101), Expect = 0.037, Method: Compositional matrix adjust. Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 5/65 (7%) Query 188 VYVRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVAL 247 +Y PM + +L++ K IC C ++ F +D +EV H+IP S GG D DN AL Sbjct 75 IYTGTPMRVSKLLKKQKDICPICKQH--FTPDD---LIEVDHIIPKSKGGKDRYDNLQAL 129 Query 248 CPNCH 252 +CH Sbjct 130 HRHCH 134 >ref|YP_001741912.1| Putative ATP dependant helicase yprA [Candidatus Cloacamonas acidaminovorans] emb|CAO81706.1| Putative ATP dependant helicase yprA [Candidatus Cloacamonas acidaminovorans] Length=863 Score = 43.5 bits (101), Expect = 0.038, Method: Compositional matrix adjust. Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 13/51 (25%) Query 207 CENCGKNAPFYLNDGNPYLEVHHVIPL----SSGGADTTDNCVALCPNCHR 253 C NCG LEVHH+IP A+ DN VALCP CHR Sbjct 698 CRNCGATGD---------LEVHHIIPFRRFEDPAEANEPDNLVALCPRCHR 739 >ref|ZP_02418181.1| hypothetical protein ANACAC_00749 [Anaerostipes caccae DSM 14662] gb|EDR98698.1| hypothetical protein ANACAC_00749 [Anaerostipes caccae DSM 14662] Length=99 Score = 43.5 bits (101), Expect = 0.038, Method: Compositional matrix adjust. Identities = 17/34 (50%), Positives = 23/34 (67%), Gaps = 0/34 (0%) Query 223 PYLEVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 P EVHH +PLS GG DN ++LC +CH ++H Sbjct 47 PVDEVHHKLPLSEGGNHNKDNLISLCKSCHAKIH 80 >ref|YP_181809.1| HNH endonuclease domain-containing protein [Dehalococcoides ethenogenes 195] gb|AAW40608.1| HNH endonuclease domain protein [Dehalococcoides ethenogenes 195] Length=115 Score = 43.5 bits (101), Expect = 0.038, Method: Compositional matrix adjust. Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 5/54 (9%) Query 206 ICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRELHYSK 259 +CE C K + + EVHH+IPL+ GG + N ++LC +CH ++H+ + Sbjct 64 LCEQCLKAGRYVAVE-----EVHHIIPLADGGTNEESNLMSLCRSCHEKIHHER 112 >gb|EDH61950.1| hypothetical protein GOS_572715 [marine metagenome] Length=270 Score = 43.5 bits (101), Expect = 0.039, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query 179 PVEVERLQKVYVRDP-MVKAWILQQSKGICENCGKNAPFYLNDGNP---YLEVHHVIPLS 234 P +R YV +P +VK + +K C+ C Y+N N Y E H+ P S Sbjct 136 PAVTDRKIFSYVTNPELVKQIKSKYTK--CQFCNYVFESYINSNNEIKQYSEAAHIKPKS 193 Query 235 SGGADTTDNCVALCPNCH 252 GG D +N + LC NCH Sbjct 194 EGGLDNLNNILCLCANCH 211 >ref|YP_001629663.1| reverse transcriptase [Bordetella petrii DSM 12804] ref|YP_001632906.1| reverse transcriptase [Bordetella petrii DSM 12804] emb|CAP41392.1| reverse transcriptase [Bordetella petrii] emb|CAP44639.1| reverse transcriptase [Bordetella petrii] Length=571 Score = 43.5 bits (101), Expect = 0.040, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 9/73 (12%) Query 185 LQKVYVRDPMVKAWILQQSKG-ICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDN 243 +Q ++ R +VK W+ Q K ICE P G HH+ GG +T +N Sbjct 492 VQSLHERRKLVKLWLAQDGKCLICEQ-----PITKETG---WHAHHIQRRVDGGKNTLEN 543 Query 244 CVALCPNCHRELH 256 V L PNCH +LH Sbjct 544 LVLLHPNCHNQLH 556 >gb|ECV22780.1| hypothetical protein GOS_2939756 [marine metagenome] Length=585 Score = 43.5 bits (101), Expect = 0.040, Method: Compositional matrix adjust. Identities = 16/31 (51%), Positives = 23/31 (74%), Gaps = 0/31 (0%) Query 226 EVHHVIPLSSGGADTTDNCVALCPNCHRELH 256 +VHH++ +GG+D +N V L PNCHR+LH Sbjct 547 DVHHIVERVNGGSDELNNLVMLHPNCHRQLH 577 >ref|ZP_07415077.2| hypothetical protein TMAG_03028 [Mycobacterium tuberculosis SUMu001] ref|ZP_07494266.2| hypothetical protein TMLG_02225 [Mycobacterium tuberculosis SUMu012] gb|EFO74299.1| hypothetical protein TMAG_03028 [Mycobacterium tuberculosis SUMu001] gb|EFP54183.1| hypothetical protein TMLG_02225 [Mycobacterium tuberculosis SUMu012] Length=243 Score = 43.5 bits (101), Expect = 0.041, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 11/66 (16%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R PM +A ++ + + C CG A V HV+P S GGA + +NCVA C Sbjct 142 ARVPMTRAALMHRDRFCCAYCGGKAD----------TVDHVVPRSRGGAHSWENCVACCS 191 Query 250 NC-HRE 254 C HR+ Sbjct 192 PCNHRK 197 >gb|ECW12781.1| hypothetical protein GOS_2775814 [marine metagenome] Length=202 Score = 43.5 bits (101), Expect = 0.041, Method: Compositional matrix adjust. Identities = 25/66 (37%), Positives = 36/66 (54%), Gaps = 8/66 (12%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNP--YLEVHHVIPL----SSGGADTTDNCVALC 248 V+ +L++ C +CG A N G P L VHHV+P ++ A+ DN V LC Sbjct 23 VRRAVLERDAFTCRHCG--AKREANAGRPGTLLHVHHVVPFRAFSTAREANRKDNLVTLC 80 Query 249 PNCHRE 254 P+CHR+ Sbjct 81 PSCHRK 86 >ref|YP_001859320.1| hypothetical protein Bphy_3106 [Burkholderia phymatum STM815] gb|ACC72274.1| conserved hypothetical protein [Burkholderia phymatum STM815] Length=106 Score = 43.5 bits (101), Expect = 0.042, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 11/81 (13%) Query 195 VKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCHRE 254 V++W +C CG+ P D HH++P + GG +T VAL CHR+ Sbjct 6 VQSWYRPPQDEVCPLCGRTIPPEQRDE------HHMVPKAEGGRET----VALHRICHRQ 55 Query 255 LHYSKNAKELIEMLYVNINRL 275 LH + +EL Y +++RL Sbjct 56 LHALFSERELA-TTYASVDRL 75 >ref|NP_489471.1| hypothetical protein alr8560 [Nostoc sp. PCC 7120] dbj|BAB77479.1| alr8560 [Nostoc sp. PCC 7120] Length=600 Score = 43.5 bits (101), Expect = 0.042, Method: Compositional matrix adjust. Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 14/102 (13%) Query 157 LLNMRVSKLIKKTLSQPEGSRKPVEVE------RLQKVYVRDPMVKAWILQQSKGICENC 210 LL R +++++ Q +GSR P + + R+ K + P+ A +L+ KG C +C Sbjct 481 LLKHRETRIVRHI--QVKGSRSPFDGDWVYWSSRMGK-HPEAPIRVATLLKMQKGKCTHC 537 Query 211 GKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCPNCH 252 G F+ D +E+ H IP S GG D+ DN L +CH Sbjct 538 G--LFFHHED---LMEIDHKIPRSQGGKDSYDNLQLLHGHCH 574 >ref|NP_856143.1| hypothetical protein Mb2496c [Mycobacterium bovis AF2122/97] ref|YP_978576.1| hypothetical protein BCG_2489c [Mycobacterium bovis BCG str. Pasteur 1173P2] ref|YP_002645533.1| hypothetical protein JTY_2483 [Mycobacterium bovis BCG str. Tokyo 172] 6 more sequence titles Length=222 Score = 43.1 bits (100), Expect = 0.043, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 11/66 (16%) Query 190 VRDPMVKAWILQQSKGICENCGKNAPFYLNDGNPYLEVHHVIPLSSGGADTTDNCVALCP 249 R PM +A ++ + + C CG A V HV+P S GGA + +NCVA C Sbjct 121 ARVPMTRAALMHRDRFCCAYCGGKAD----------TVDHVVPRSRGGAHSWENCVACCS 170 Query 250 NC-HRE 254 C HR+ Sbjct 171 PCNHRK 176 >ref|NP_216985.1| hypothetical protein Rv2469c [Mycobacterium tuberculosis H37Rv] ref|NP_337031.1| hypothetical protein MT2545 [Mycobacterium tuberculosis CDC1551] ref|YP_001283827.1| hypothetical protein MRA_2495 [Mycobacterium tuberculosis H37Ra] 69 more sequence titles